Impaired aquaporins expression in the gastrointestinal tract of rat after mercury exposure

Journal of Applied Toxicology

Volumn 36, Issue 1, 2016, Pages 113-120

  Bottino, Cinzia ^a   Vázquez, Marta ^b   Devesa, Vicenta ^b   Laforenza, Umberto ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b INSTITUTO DE AGROQUÍMICA Y TECNOLOGÍA DE ALIMENTOS CSIC   (Spain)

Author keywords

Aquaporins; Colon; Inorganic mercury; Methylmercury; Small intestine; Stomach; Water channels

Indexed keywords

AQUAPORIN; AQUAPORIN 3; AQUAPORIN 4; AQUAPORIN 6; AQUAPORIN 7; AQUAPORIN 8; MERCURY; MESSENGER RNA; METHYLMERCURY; MERCURIC CHLORIDE; METHYLMERCURIC CHLORIDE; METHYLMERCURY DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DOWN REGULATION; GASTROINTESTINAL TRACT; JEJUNUM; LARGE INTESTINE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMALL INTESTINE; STOMACH; WATER FLOW; ANIMAL; DRUG EFFECTS; GENETICS; METABOLISM; PHYSIOLOGY; WISTAR RAT;

ANIMALS; AQUAPORINS; GASTROINTESTINAL TRACT; MALE; MERCURIC CHLORIDE; METHYLMERCURY COMPOUNDS; RATS; RATS, WISTAR;

EID: 84952639492     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.3151     Document Type: Article

References (54)

1. Arena JM. 1971. Treatment of mercury poisoning. Mod. Treat. 8: 619-625.
2. Banerjee S, Bhattacharya S. 1995. Histopathological changes induced by chronic nonlethal levels of elsan, mercury, and ammonia in the small intestine of Channa punctatus (Bloch). Ecotoxicol. Environ. Saf. 31: 62-68.
3. Benga G. 2012. On the definition, nomenclature and classification of water channel proteins (aquaporins and relatives). Mol. Aspects Med. 33: 514-517.
4. Böhme M, Diener M, Mestres P, Rummel W. 1992. Direct and indirect actions of HgCl2 and methyl mercury chloride on permeability and chloride secretion across the rat colonic mucosa. Toxicol. Appl. Pharmacol. 114: 285-294.
5. 0, + and the transport of thiol-S-conjugates of methylmercury. J. Pharmacol. Exp. Ther. 319: 948-956.
6. Bridges CC, Zalups RK. 2010. Transport of inorganic mercury and methylmercury in target tissues and organs. J. Toxicol. Environ. Health B Crit. Rev. 13: 385-410.
7. Calamita G, Mazzone A, Bizzoca A, Cavalier A, Cassano G, Thomas D, Svelto M. 2001. Expression and immunolocalization of the aquaporin-8 water channel in rat gastrointestinal tract. Eur. J. Cell Biol. 80: 711-719.
8. Cheng TF, Choudhuri S, Muldoon-Jacobs K. 2012. Epigenetic targets of some toxicologically relevant metals: a review of the literature. J. Appl. Toxicol. 32: 643-653.
9. Clarkson TW, Magos L. 2006. The toxicology of mercury and its chemical compounds. Crit. Rev. Toxicol. 36: 609-662.
10. Durbin RP. 1979. Osmotic flow of water in isolated frog gastric mucosa. Am. J. Physiol. 236: E63-E69.
11. Elkjaer M, Nejsum LN, Gresz V, Kwon T, Jensen U, Frøkiaer J, Nielsen S. 2001. Immunolocalization of aquaporin-8 in rat kidney, gastrointestinal tract, testis, and airways. Am. J. Physiol. Renal Physiol. 281: F1047-F1057.
12. Frigeri A, Gropper MA, Umenishi F, Kawashima M, Brown D, Verkman AS. 1995. Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues. J. Cell Sci. 108: 2993-3002.
13. Häggqvist B, Havarinasab S, Björn E, Hultman P. 2005. The immunosuppressive effect of methylmercury does not preclude development of autoimmunity in genetically susceptible mice. Toxicology 208: 149-164.
14. Havarinasab S, Hultman P. 2005. Organic mercury compounds and autoimmunity. Autoimmun. Rev. 4: 270-275.
15. Hong YS, Kim YM, Lee KE. 2012. Methylmercury exposure and health effects. J. Prev. Med. Public Health 45: 353-363.
16. IARC (International Agency for Cancer Research). 1993. Monographs on the Evaluation of Carcinogenic Risks to Humans. Beryllium, cadmium, mercury, and exposures in the glass manufacturing industry, Vol. 58.
17. Ikarashi N, Kon R, Iizasa T, Suzuki N, Hiruma R, Suenaga K, Toda T, Ishii M, Hoshino M, Ochiai W, Sugiyama K. 2012. Inhibition of aquaporin-3 water channel in the colon induces diarrhea. Biol. Pharm. Bull. 35: 957-962.
18. Ishibashi K, Hara S, Kondo S. 2009. Aquaporin water channels in mammals. Clin. Exp. Nephrol. 13: 107-117.
19. JEFCA (Joint FAO/WHO Expert Committee on Food Additives). 2004. Safety evaluation of certain food additives and contaminants. WHO Food Additives Series No. 52.
20. JEFCA (Joint FAO/WHO Expert Committee on Food Additives). 2011. Safety evaluation of certain contaminants in food. WHO Food Additives Series No. 63.
21. Jung JS, Preston GM, Smith BL, Guggino WB, Agre P. 1994. Molecular structure of the water channel through aquaporin CHIP. The hourglass model. J. Biol. Chem. 269: 14648-14654.
22. Kamijo Y, Hayashi I, Yoshimura K, Soma K. 2004. Effect of milk on intestinal fluid accumulation and renal injury following mercuric chloride ingestion in rats. J. Appl. Toxicol. 24: 129-134.
23. Koyama Y, Yamamoto T, Tani T, Nihei K, Kondo D, Funaki H, Yaoita E, Kawasaki K, Sato N, Hatakeyama K, Kihara I. 1999. Expression and localization of aquaporins in rat gastrointestinal tract. Am. J. Physiol. 276: C621-C627.
24. Laforenza U. 2012. Water channel proteins in the gastrointestinal tract. Mol. Aspects Med. 33: 642-650.
25. Laforenza U, Cova E, Gastaldi G, Tritto S, Grazioli M, LaRusso NF, Splinter PL, D'Adamo P, Tosco M, Ventura U. 2005a. Aquaporin-8 is involved in water transport in isolated superficial colonocytes from rat proximal colon. J. Nutr. 135: 2329-2336.
26. Laforenza U, Gastaldi G, Grazioli M, Cova E, Tritto S, Faelli A, Calamita G, Ventura U. 2005b. Expression and immunolocalization of aquaporin-7 in rat gastrointestinal tract. Biol. Cell 97: 605-613.
27. Laforenza U, Gastaldi G, Polimeni M, Tritto S, Tosco M, Ventura U, Scaffino MF, Yasui M. 2009. Aquaporin-6 is expressed along the rat gastrointestinal tract and upregulated by feeding in the small intestine. BMC Physiol. 9: 18.
28. Ma T, Verkman A. 1999. Aquaporin water channels in gastrointestinal physiology. J. Physiol. 517: 317-326.
29. Masyuk A, Marinelli R, LaRusso N. 2002. Water transport by epithelia of the digestive tract. Gastroenterology 122: 545-562.
30. McGinnis WR. 2001. Mercury and autistic gut disease. Environ. Health Perspect. 109: A303-A304.
31. Mitsumori K, Hirano M, Ueda H, Maita K, Shirasu Y. 1990. Chronic toxicity and carcinogenicity of methylmercury chloride in B6C3F1 mice. Fundam. Appl. Toxicol. 14: 179-190.
32. Murota K, Yoshida M, Ishibashi N, Yamazaki H, Minami T. 2012. Direct absorption of methyl mercury by lymph. Biol. Trace Elem. Res. 145: 349-354.
33. Nagashima K. 1997. A review of experimental methylmercury toxicity in rats: neuropathology and evidence for apoptosis. Toxicol. Pathol. 25: 624-631.
34. Norseth T, Clarkson TW. 1971. Intestinal transport of 203Hg-labeled methyl mercury chloride. Role of biotransformation in rats. Arch. Environ. Health. 22: 568-577.
35. NTP (National Toxicology Program). 1993. Toxicology and carcinogenesis studies of mercuric chloride (CAS No. 7487-94-7) in F344 rats and B3C3F1 mice (gavage studies). Research Triangle Park, NC: National Toxicology Program, U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, Technical Report Series No. 408.
36. Oehme FW. 1972. Mechanisms of heavy metal toxicities. Clin. Toxicol. 5: 151-167.
37. Onishchenko N, Karpova N, Sabri F, Castren E, Ceccatelli S. 2008. Long-lasting depression-like behavior and epigenetic changes of BDNF gene expression induced by perinatal exposure to methylmercury. J. Neurochem. 106: 1378-1387.
38. Pheng SR, Auger C, Chakrabarti S, Massicotte E, Lamontagne L. 2003. Sensitivity to methylmercury-induced autoimmune disease in mice correlates with resistance to apoptosis of activated CD4+ lymphocytes. J. Autoimmun. 20: 147-160.
39. Pilsner JR, Lazarus AL, Nam DH, Letcher RJ, Sonne C, Dietz R, Basu N. 2010. Mercury-associated DNA hypomethylation in polar bear brains via the LUminometric Methylation Assay: a sensitive method to study epigenetics in wildlife. Mol. Ecol. 19: 307-314.
40. Preston GM, Jung JS, Guggino WB, Agre P. 1993. The mercury-sensitive residue at cysteine 189 in the CHIP28 water channel. J. Biol. Chem. 268: 17-20.
41. Ramírez-Lorca R, Vizuete ML, Venero JL, Revuelta M, Cano J, Ilundáin AA, Echevarría M. 1999. Localization of aquaporin-3 mRNA and protein along the gastrointestinal tract of Wistar rats. Pflugers Arch. 438: 94-100.
42. Sasser LB, Jarboe GE, Walter BK, Kelman BJ. 1978. Absorption of mercury from ligated segments of the rat gastrointestinal tract. Proc. Soc. Exp. Biol. Med. 157: 57-60.
43. Seko Y, Takahashi M, Hasegawa T, Miura T. 2001. Intestinal absorption of mercury in vitro from intestinal contents of methylmercury administered mice. J. Health Sci. 47: 508-511.
44. Thiagarajah J, Zhao D, Verkman A. 2007. Impaired enterocyte proliferation in aquaporin-3 deficiency in mouse models of colitis. Gut 56: 1529-1535.
45. Tritto S, Gastaldi G, Zelenin S, Grazioli M, Orsenigo MN, Ventura U, Laforenza U, Zelenina M. 2007. Osmotic water permeability of rat intestinal brush border membrane vesicles: involvement of aquaporin-7 and aquaporin-8 and effect of metal ions. Biochem. Cell Biol. 85: 675-684.
46. Verkman AS. 2008. Mammalian aquaporins: diverse physiological roles and potential clinical significance. Expert Rev. Mol. Med. 10: e13.
47. Wagner C, Sudati JH, Nogueira CW, Rocha JB. 2010. In vivo and in vitro inhibition of mice thioredoxin reductase by methylmercury. Biometals 23: 1171-1177.
48. Wang KS, Komar AR, Ma T, Filiz F, McLeroy J, Hoda K, Verkman AS, Bastidas JA. 2000. Gastric acid secretion in aquaporin-4 knockout mice. Am. J. Physiol. Gastrointest. Liver Physiol. 279: G448-G453.
49. Yaginuma-Sakurai K, Murata K, Shimada M, Nakai K, Kurokawa N, Kameo S, Satoh H. 2010. Intervention study on cardiac autonomic nervous effects of methylmercury from seafood. Neurotoxicol. Teratol. 32: 240-245.
50. Yasui M. 2009. pH regulated anion permeability of aquaporin-6. Handb. Exp. Pharmacol. 190: 299-308.
51. Yasui M, Hazama A, Kwon TH, Nielsen S, Guggino WB, Agre P. 1999. Rapid gating and anion permeability of an intracellular aquaporin. Nature 402: 184-187.
52. Yoshida M, Satoh H, Igarashi M, Akashi K, Yamamura Y, Yoshida K. 1997. Acute mercury poisoning by intentional ingestion of mercuric chloride. Tohoku J. Exp. Med. 182: 347-352.
53. Zahir F, Rizwi SJ, Haq SK, Khan RH. 2005. Low dose mercury toxicity and human health. Environ. Toxicol. Pharmacol. 20: 351-360.
54. Zhang R, van Hoek AN, Biwersi J, Verkman AS. 1993. A point mutation at cysteine 189 blocks the water permeability of rat kidney water channel CHIP28k. Biochemistry 32: 2938-2941.