Allergy immunotherapy for allergic rhinitis effectively prevents asthma: Results from a large retrospective cohort study

Journal of Allergy and Clinical Immunology

Volumn 136, Issue 6, 2015, Pages 1511-1516

  Schmitt, Jochen ^a   Schwarz, Kristin ^a   Stadler, Erich ^a   Wüstenberg, Eike Gunther ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Allergic rhinitis; allergy immunotherapy; asthma; cohort study; effectiveness; epidemiology; prevention

Indexed keywords

ADULT; ALLERGIC RHINITIS; ARTICLE; ASTHMA; COHORT ANALYSIS; FEMALE; HUMAN; IMMUNOTHERAPY; INCIDENCE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK ASSESSMENT; TREATMENT OUTCOME; ADOLESCENT; CHILD; DESENSITIZATION; GERMANY; MIDDLE AGED; RHINITIS, ALLERGIC; RISK; YOUNG ADULT;

ADOLESCENT; ADULT; ASTHMA; CHILD; DESENSITIZATION, IMMUNOLOGIC; FEMALE; GERMANY; HUMANS; INCIDENCE; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; RHINITIS, ALLERGIC; RISK; YOUNG ADULT;

EID: 84952636766     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.07.038     Document Type: Article

References (30)

1. B. Bjorksten, T. Clayton, P. Ellwood, A. Stewart, and D. Strachan Worldwide time trends for symptoms of rhinitis and conjunctivitis: phase III of the International Study of Asthma and Allergies in Childhood Pediatr Allergy Immunol 19 2008 110 124
2. W. Maziak, T. Behrens, T.M. Brasky, H. Duhme, P. Rzehak, S.K. Weiland, and et al. Are asthma and allergies in children and adolescents increasing? Results from ISAAC phase I and phase III surveys in Munster, Germany Allergy 58 2003 572 579
3. L.M. Wheatley, and A. Togias Clinical practice. Allergic rhinitis N Engl J Med 372 2015 456 463
4. S. Yonekura, Y. Okamoto, S. Horiguchi, D. Sakurai, H. Chazono, T. Hanazawa, and et al. Effects of aging on the natural history of seasonal allergic rhinitis in middle-aged subjects in South Chiba, Japan Int Arch Allergy Immunol 157 2012 73 80
5. E.O. Meltzer, and D.A. Bukstein The economic impact of allergic rhinitis and current guidelines for treatment Ann Allergy Asthma Immunol 106 suppl 2011 S12 S16
6. G.M. Miraglia Del, A. Marseglia, S. Leonardi, R.M. La, C. Salpietro, F.P. Brunese, and et al. Allergic rhinitis and quality of life in children Int J Immunopathol Pharmacol 24 suppl 2011 25 28
7. K. Trikojat, A. Buske-Kirschbaum, J. Schmitt, and F. Plessow Altered performance in attention tasks in patients with seasonal allergic rhinitis: seasonal dependency and association with disease characteristics Psychol Med 45 2015 1289 1299
8. A.N. Greiner, P.W. Hellings, G. Rotiroti, and G.K. Scadding Allergic rhinitis Lancet 378 2011 2112 2122
9. A.S. Ismaila, A.P. Sayani, M. Marin, and Z. Su Clinical, economic, and humanistic burden of asthma in Canada: a systematic review BMC Pulm Med 13 2013 70
10. S. Croisant Epidemiology of asthma: prevalence and burden of disease Adv Exp Med Biol 795 2014 17 29
11. G. Passalacqua, and S.R. Durham Allergic rhinitis and its impact on asthma update: allergen immunotherapy J Allergy Clin Immunol 119 2007 881 891
12. J. Bousquet, H.J. Schunemann, B. Samolinski, P. Demoly, C.E. Baena-Cagnani, C. Bachert, and et al. Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs J Allergy Clin Immunol 130 2012 1049 1062
13. J. Bousquet, N. Khaltaev, A.A. Cruz, J. Denburg, W.J. Fokkens, A. Togias, and et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen) Allergy 63 suppl 86 2008 8 160
14. C. Moller, S. Dreborg, H.A. Ferdousi, S. Halken, A. Host, L. Jacobsen, and et al. Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study) J Allergy Clin Immunol 109 2002 251 256
15. E. Novembre, E. Galli, F. Landi, C. Caffarelli, M. Pifferi, E. De Marco, and et al. Coseasonal sublingual immunotherapy reduces the development of asthma in children with allergic rhinoconjunctivitis J Allergy Clin Immunol 114 2004 851 857
16. European Medicines Agency. Committee for Medicinal Products for Human Use (CHMP) and Efficacy Working Party (EWP): guideline on the clinical development of products for specific immunotherapy for the treatment of allergic diseases. Available at: http://www.ema.europa.eu/docs/en-GB/document-library/Scientific-guideline/2009/09/WC500003605.pdf. Accessed April 2015.
17. J. Schmitt, M. Romanos, N.M. Schmitt, M. Meurer, and W. Kirch Atopic eczema and attention-deficit/hyperactivity disorder in a population-based sample of children and adolescents JAMA 301 2009 724 726
18. J. Schmitt, M. Romanos, A. Pfennig, K. Leopold, and M. Meurer Psychiatric comorbidity in adult eczema Br J Dermatol 161 2009 878 883
19. J. Schmitt, U. Maywald, N.M. Schmitt, M. Meurer, and W. Kirch Cardiovascular comorbidity in patients with chronic inflammatory skin diseases: a case-control study utilising a population-based administrative database Ital J Public Health 5 2008 187 193
20. [Good practice of secondary data analysis, first revision] Gesundheitswesen 70 2008 54 60
21. Global Initiative for Asthma. From the Global Strategy for Asthma Management and Prevention, Global Initiative for Asthma (GINA). Available at: http://www.ginasthma.org/. Accessed April 2015.
22. B. Rosner Fundamentals of Biostatistics 5th ed. 2000 Duxbury Pacific Grove (CA)
23. B. Niggemann, L. Jacobsen, S. Dreborg, H.A. Ferdousi, S. Halken, A. Host, and et al. Five-year follow-up on the PAT study: specific immunotherapy and long-term prevention of asthma in children Allergy 61 2006 855 859
24. E. Valovirta, A.K. Berstad, B.J. de, A. Bufe, P. Eng, S. Halken, and et al. Design and recruitment for the GAP trial, investigating the preventive effect on asthma development of an SQ-standardized grass allergy immunotherapy tablet in children with grass pollen-induced allergic rhinoconjunctivitis Clin Ther 33 2011 1537 1546
25. H. Henmar, G. Lund, L. Lund, A. Petersen, and P.A. Wurtzen Allergenicity, immunogenicity and dose-relationship of three intact allergen vaccines and four allergoid vaccines for subcutaneous grass pollen immunotherapy Clin Exp Immunol 153 2008 316 323
26. B. Heydenreich, I. Bellinghausen, S. Lorenz, H. Henmar, D. Strand, P.A. Wurtzen, and et al. Reduced in vitro T-cell responses induced by glutaraldehyde-modified allergen extracts are caused mainly by retarded internalization of dendritic cells Immunology 136 2012 208 217
27. S.R. Durham, S.M. Walker, E.M. Varga, M.R. Jacobson, F. O'Brien, W. Noble, and et al. Long-term clinical efficacy of grass-pollen immunotherapy N Engl J Med 341 1999 468 475
28. L. Jacobsen, B. Niggemann, S. Dreborg, H.A. Ferdousi, S. Halken, A. Host, and et al. Specific immunotherapy has long-term preventive effect of seasonal and perennial asthma: 10-year follow-up on the PAT study Allergy 62 2007 943 948
29. S.R. Durham, W. Emminger, A. Kapp, J.G. De Monchy, S. Rak, G.K. Scadding, and et al. SQ-standardized sublingual grass immunotherapy: confirmation of disease modification 2 years after 3 years of treatment in a randomized trial J Allergy Clin Immunol 129 2012 717 725
30. J. Biermann, H. Merk, and W. Wehrmann Allergic disorders of the respiratory tract - findings from a large patient sample in the German statutory health insurance system Allergo J 22 2013 366 373