Psychotropic drugs for the management of cancer-related fatigue: a systematic review and meta-analysis

European Journal of Cancer Care

Volumn 25, Issue 6, 2016, Pages 970-979

  Qu, D ^a,b   Zhang, Z ^a,c   Yu, X ^a,c   Zhao, J ^a,c   Qiu, F ^a,c   Huang, J ^a,c  

^a THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Nanxing Community Health Service Center   (China)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

cancer related fatigue; methylphenidate; modafinil; psychotropic drugs

Indexed keywords

BENZHYDRYL DERIVATIVE; METHYLPHENIDATE; MODAFINIL; PSYCHOTROPIC AGENT;

COMPLICATION; FATIGUE; HUMAN; META ANALYSIS; NEOPLASM;

BENZHYDRYL COMPOUNDS; FATIGUE; HUMANS; METHYLPHENIDATE; NEOPLASMS; PSYCHOTROPIC DRUGS;

EID: 84952333635     PISSN: 09615423     EISSN: 13652354     Source Type: Journal    
DOI: 10.1111/ecc.12397     Document Type: Article

References (45)

1. Berger A.M., Gerber L.H. & Mayer D.K. (2012) Cancer-related fatigue: implications for breast cancer survivors. Cancer 118, 2261–2269.
2. Bower J.E., Ganz P.A., Desmond K.A., Rowland J.H., Meyerowitz B.E. & Belin T.R. (2000) Fatigue in breast cancer survivors: occurrence, correlates, and impact on quality of life. Journal of Clinical Oncology 18, 743–753.
3. Bower J.E., Bak K., Berger A., Breitbart W., Escalante C.P., Ganz P.A., Schnipper H.H., Lacchetti C., Ligibel J.A., Lyman G.H., Ogaily M.S., Pirl W.F. & Jacobsen P.B. (2014) Screening, assessment, and management of fatigue in adult survivors of cancer: an American Society of Clinical Oncology Clinical Practice Guideline adaptation. Journal of Clinical Oncology 32, 1840–1850.
4. Bruera E. & Yennurajalingam S. (2010) Challenge of managing cancer-related fatigue. Journal of Clinical Oncology 28, 3671–3672.
5. Bruera E., Valero V., Driver L., Shen L., Willey J., Zhang T. & Palmer J.L. (2006) Patient-controlled methylphenidate for cancer fatigue: a double-blind, randomized, placebo-controlled trial. Journal of Clinical Oncology 24, 2073–2078.
6. Bruera E., Yennurajalingam S., Palmer J.L., Perez-Cruz P.E., Frisbee-Hume S., Allo J.A., Williams J.L. & Cohen M.Z. (2013) Methylphenidate and/or a nursing telephone intervention for fatigue in patients with advanced cancer: a randomized, placebo-controlled, phase II trial. Journal of Clinical Oncology 31, 2421–2427.
7. Butler J.M. Jr, Case L.D., Atkins J., Frizzell B., Sanders G., Griffin P., Lesser G., Mcmullen K., Mcquellon R., Naughton M., Rapp S., Stieber V. & Shaw E.G. (2007) A phase III, double-blind, placebo-controlled prospective randomized clinical trial of d-Threo-methylphenidate HCl in brain tumor patients receiving radiation therapy. International Journal of Radiation Oncology, Biology, Physics 69, 1496–1501.
8. Campos M.P., Hassan B.J., Riechelmann R. & Del Giglio A. (2011) Cancer-related fatigue: a practical review. Annals of Oncology 22, 1273–1279.
9. Cella D.D.K., Breitbart W. & Curt G. & Fatigue Coalition (2001) Cancer-related fatigue: prevalence of proposed diagnostic criteria in a United States sample of cancer survivors. Journal of Clinical Oncology 19, 3385–3391.
10. Cramp F. & Byron-Daniel J. (2012) Exercise for the management of cancer-related fatigue. Cochrane Database of Systematic Review 14, CD006145.
11. De Sanctis V., Agolli L., Visco V., Monaco F., Muni R., Spagnoli A., Campanella B., Valeriani M., Minniti G., Osti M.F., Amanti C., Pellegrini P., Brunetti S., Costantini A., Alfo M., Torrisi M.R., Marchetti P. & Enrici R.M. (2014) Cytokines, fatigue, and cutaneous erythema in early stage breast cancer patients receiving adjuvant radiation therapy. BioMed Research International 2014, 523568.
12. Denlinger C.S., Ligibel J.A., Are M., Baker K.S., Demark-Wahnefried W., Friedman D.L., Goldman M., Jones L., King A., Ku G.H., Kvale E., Langbaum T.S., Leonardi-Warren K., Mccabe M.S., Melisko M., Montoya J.G., Mooney K., Morgan M.A., Moslehi J.J., O'Connor T., Overholser L., Paskett E.D., Raza M., Syrjala K.L., Urba S.G., Wakabayashi M.T., Zee P. & Mcmillian N.; Freedman-Cass D (2014) Survivorship: fatigue, version 1.2014. Journal of the National Comprehensive Cancer Network 12, 876–887.
13. Fuhrmann K., Mehnert A., Geue K. & Hinz A. (2014) Fatigue in breast cancer patients: psychometric evaluation of the fatigue questionnaire EORTC QLQ-FA13. Breast Cancer 527, 1–8.
14. Galiano-Castillo N., Ariza-Garcia A., Cantarero-Villanueva I., Fernandez-Lao C., Diaz-Rodriguez L. & Arroyo-Morales M. (2014) Depressed mood in breast cancer survivors: associations with physical activity, cancer-related fatigue, quality of life, and fitness level. European Journal of Oncology Nursing 18, 206–210.
15. Goldstein D., Bennett B.K., Webber K., Boyle F., De Souza P.L., Wilcken N.R., Scott E.M., Toppler R., Murie P., O'Malley L., Mccourt J., Friedlander M., Hickie I.B. & Lloyd A.R. (2012) Cancer-related fatigue in women with breast cancer: outcomes of a 5-year prospective cohort study. Journal of Clinical Oncology 30, 1805–1812.
16. Hovey E., De Souza P., Marx G., Parente P., Rapke T., Hill A., Bonaventura A., Michele A., Craft P., Abdi E., Lloyd A. & Investigators M. (2014) Phase III, randomized, double-blind, placebo-controlled study of modafinil for fatigue in patients treated with docetaxel-based chemotherapy. Supportive Care in Cancer 22, 1233–1242.
17. Huang X., Zhang Q., Kang X., Song Y. & Zhao W. (2010) Factors associated with cancer-related fatigue in breast cancer patients undergoing endocrine therapy in an urban setting: a cross-sectional study. BMC Cancer 10, 453.
18. Hwang S.S., Chang V.T., Rue M. & Kasimis B. (2003) Multidimensional independent predictors of cancer-related fatigue. Journal of Pain and Symptom Management 26, 604–614.
19. Jadad A.R., Moore R.A, Carroll D, Jenkinson C., Reynolds D.J., Gavaghan D.J. & Mcquay H.J. (1996) Assessing the quality of reports of randomized clinical trials: is blinding necessary? Controlled Clinical Trials 17, 1–12.
20. Jean-Pierre P., Morrow G.R., Roscoe J.A., Heckler C., Mohile S., Janelsins M., Peppone L., Hemstad A., Esparaz B.T. & Hopkins J.O. (2010) A phase 3 randomized, placebo-controlled, double-blind, clinical trial of the effect of modafinil on cancer-related fatigue among 631 patients receiving chemotherapy: a University of Rochester Cancer Center Community Clinical Oncology Program Research base study. Cancer 116, 3513–3520.
21. Koornstra R.H., Peters M., Donofrio S., Van Den Borne B. & De Jong F.A. (2014) Management of fatigue in patients with cancer – a practical overview. Cancer Treatment Reviews 40, 791–799.
22. Lee S., Jerng U.M., Liu Y., Kang J.W., Nam D. & Lee J.D. (2014) The effectiveness and safety of moxibustion for treating cancer-related fatigue: a systematic review and meta-analyses. Supportive Care in Cancer 22, 1429–1440.
23. Liberati A., Altman D.G., Tetzlaff J., Mulrow C., Gøtzsche P.C., Ioannidis J.P., Clarke M., Devereaux P.J., Kleijnen J. & Moher D. (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Medicine 6, e1000100.
24. Lower E.E., Fleishman S., Cooper A., Zeldis J., Faleck H., Yu Z. & Manning D. (2009) Efficacy of dexmethylphenidate for the treatment of fatigue after cancer chemotherapy: a randomized clinical trial. Journal of Pain and Symptom Management 38, 650–662.
25. Lundorff L.E., Jonsson B.H. & Sjogren P. (2009) Modafinil for attentional and psychomotor dysfunction in advanced cancer: a double-blind, randomised, cross-over trial. Palliative Medicine 23, 731–738.
26. Minton O., Richardson A., Sharpe M., Hotopf M. & Stone P. (2008) A systematic review and meta-analysis of the pharmacological treatment of cancer-related fatigue. Journal of the National Cancer Institute 100, 1155–1166.
27. Minton O.R.A., Sharpe M., Hotopf M. & Stone P. (2010) Drug therapy for the management of cancer-related fatigue. Cochrane Database of Systematic Review 7, CD006704.
28. Minton O., Richardson A., Sharpe M., Hotopf M. & Stone P.C. (2011) Psychostimulants for the management of cancer-related fatigue: a systematic review and meta-analysis. Journal of Pain and Symptom Management 41, 761–767.
29. Mock V. (2004) Evidence-based treatment for cancer-related fatigue. Journal of the National Cancer Institute Monographs 2004, 112–118.
30. Molassiotis A., Bardy J., Finnegan-John J., Mackereth P., Ryder D.W., Filshie J., Ream E. & Richardson A. (2012) Acupuncture for cancer-related fatigue in patients with breast cancer: a pragmatic randomized controlled trial. Journal of Clinical Oncology 30, 4470–4476.
31. Molassiotis A., Bardy J., Finnegan-John J., Mackereth P., Ryder W.D., Filshie J., Ream E., Eaton D. & Richardson A. (2013) A randomized, controlled trial of acupuncture self-needling as maintenance therapy for cancer-related fatigue after therapist-delivered acupuncture. Annals of Oncology 24, 1645–1652.
32. Moraska A.R., Sood A., Dakhil S.R., Sloan J.A., Barton D., Atherton P.J., Suh J.J., Griffin P.C., Johnson D.B., Ali A., Silberstein P.T., Duane S.F. & Loprinzi C.L. (2010) Phase III, randomized, double-blind, placebo-controlled study of long-acting methylphenidate for cancer-related fatigue: North Central Cancer Treatment Group NCCTG-N05C7 trial. Journal of Clinical Oncology 28, 3673–3679.
33. Neefjes E.C., Van Der Vorst M.J., Blauwhoff-Buskermolen S. & Verheul H.M. (2013) Aiming for a better understanding and management of cancer-related fatigue. The Oncologist 18, 1135–1143.
34. Paulsen O., Klepstad P., Rosland J.H., Aass N., Albert E., Fayers P. & Kaasa S. (2014) Efficacy of methylprednisolone on pain, fatigue, and appetite loss in patients with advanced cancer using opioids: a randomized, placebo-controlled, double-blind trial. Journal of Clinical Oncology 29, 3221–3228.
35. Portenoy R.K. (2000) Cancer-related fatigue: an immense problem. The Oncologist 5, 350–352.
36. Posadzki P., Moon T.W., Choi T.Y., Park T.Y., Lee M.S. & Ernst E. (2013) Acupuncture for cancer-related fatigue: a systematic review of randomized clinical trials. Supportive Care in Cancer 21, 2067–2073.
37. Richard P.O., Fleshner N.E., Bhatt J.R., Hersey K.M., Chahin R. & Alibhai S.M. (2014) A phase II, randomized, double-blind, placebo-controlled trial of methylphenidate for reduction of fatigue in prostate cancer patients receiving LHRH-agonist therapy. BJU International 55, 1–9.
38. Roth A.J., Nelson C., Rosenfeld B., Scher H., Slovin S., Morris M., O'shea N., Arauz G. & Breitbart W. (2010) Methylphenidate for fatigue in ambulatory men with prostate cancer. Cancer 116, 5102–5110.
39. Saligan L.N. & Kim H.S. (2012) A systematic review of the association between immunogenomic markers and cancer-related fatigue. Brain, Behavior, and Immunity 26, 830–848.
40. Spathis A., Fife K., Blackhall F., Dutton S., Bahadori R., Wharton R., O'brien M., Stone P., Benepal T., Bates N. & Wee B. (2014) Modafinil for the treatment of fatigue in lung cancer: results of a placebo-controlled, double-blind, randomized trial. Journal of Clinical Oncology 32, 1882–1888.
41. Stone P.C. & Minton O. (2008) Cancer-related fatigue. European Journal of Cancer Care 44, 1097–1104.
42. Su C.X., Wang L.Q., Grant S.J. & Liu J.P. (2014) Chinese herbal medicine for cancer-related fatigue: a systematic review of randomized clinical trials. Complementary Therapies in Medicine 22, 567–579.
43. Yellen S.B., Cella D.F., Webster K., Blendowski C. & Kaplan E. (1997) Measuring fatigue and other anemia related symptoms with the Functional Assessment of Cancer Therapy (FACT) measurement system. Journal of Pain and Symptom Management 13, 63–74.
44. Yennurajalingam S., Frisbee-Hume S., Palmer J.L., Delgado-Guay M.O., Bull J., Phan A.T., Tannir N.M., Litton J.K., Reddy A., Hui D., Dalal S., Massie L., Reddy S.K. & Bruera E. (2013) Reduction of cancer-related fatigue with dexamethasone: a double-blind, randomized, placebo-controlled trial in patients with advanced cancer. Journal of Clinical Oncology 31, 3076–3082.
45. Zhang S., Zeng D., Peng Y., Yang Y., Zhuang X., Li Z., Wang M., Chen L. & Zhang H. (2014) Cancer-related fatigue and chemotherapy-associated adverse effects: correlation with TNF-alpha, IL-1 and 17-hydroxycorticosteroids. Future Oncology 9, 1619–1626.