Effect of opioids vs NSAIDs and larger vs smaller chest tube size on pain control and pleurodesis efficacy among patients with malignant pleural effusion: The TIME1 Randomized Clinical Trial

JAMA - Journal of the American Medical Association

Volumn 314, Issue 24, 2015, Pages 2641-2653

  Rahman, Najib M ^a,b   Pepperell, Justin ^c   Rehal, Sunita ^d   Saba, Tarek ^e   Tang, Augustine ^e   Ali, Nabeel ^f   West, Alex ^g   Hettiarachchi, Gihan ^g   Mukherjee, Dipak ^h   Samuel, Johnson ^f   Bentley, Andrew ⁱ   Dowson, Lee ^j   Miles, Jonathan ^k   Frank Ryan, C ^l   Yoneda, Ken Y ^m   Chauhan, Anoop ⁿ   Corcoran, John P ^a   Psallidas, Ioannis ^a   Wrightson, John M ^a,b   Hallifax, Rob ^a   Davies, Helen E ^o   Gary Lee, Y C ^p   Dobson, Melissa ^a   Hedley, Emma L ^a   Seaton, Douglas ^q   Russell, Nicky ^a   Chapman, Margaret ^a   McFadyen, Bethan M ^a   Shaw, Rachel A ^a   Davies, Robert J O ^a   Maskell, Nick A ^r   Nunn, Andrew J ^d   Miller, Robert F ^d   more..

^a CHURCHILL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c MUSGROVE PARK HOSPITAL   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e BLACKPOOL TEACHING HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^f KING S MILL HOSPITAL   (United Kingdom)

^g MEDWAY MARITIME HOSPITAL   (United Kingdom)

^h BASILDON HOSPITAL   (United Kingdom)

ⁱ MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^j ROYAL WOLVERHAMPTON HOSPITALS NHS TRUST   (United Kingdom)

^k ROTHERHAM GENERAL HOSPITAL   (United Kingdom)

^l VANCOUVER COASTAL HEALTH   (Canada)

^m UNIVERSITY OF CALIFORNIA   (United States)

ⁿ QUEEN ALEXANDRA HOSPITAL   (United Kingdom)

^o CARDIFF AND VALE UNIVERSITY HEALTH BOARD   (United Kingdom)

^p UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^q IPSWICH HOSPITAL   (United Kingdom)

^r SOUTHMEAD HOSPITAL   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

IBUPROFEN; MORPHINE; NARCOTIC ANALGESIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT;

ADULT; AGED; ANALGESIA; ARTICLE; CHEST TUBE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE CONTROL; DOSE RESPONSE; DRUG DOSE ESCALATION; DRUG EFFICACY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MALIGNANT PLEURA EFFUSION; MULTICENTER STUDY; PATIENT COMPLIANCE; PHASE 3 CLINICAL TRIAL; PLEURODESIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; THORACOSCOPY; THORAX PAIN; TREATMENT FAILURE; TREATMENT OUTCOME; TREATMENT PLANNING; ADVERSE EFFECTS; ALGORITHM; CLINICAL TRIAL; COMPLICATION; CONFIDENCE INTERVAL; DEVICES; EQUIPMENT DESIGN; PAIN MEASUREMENT; PLEURAL EFFUSION, MALIGNANT; PROCEDURES; SALVAGE THERAPY; STATISTICS AND NUMERICAL DATA;

AGED; ALGORITHMS; ANALGESIA; ANALGESICS, OPIOID; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHEST TUBES; CONFIDENCE INTERVALS; EQUIPMENT DESIGN; FEMALE; HUMANS; MALE; PAIN MANAGEMENT; PAIN MEASUREMENT; PLEURAL EFFUSION, MALIGNANT; PLEURODESIS; SALVAGE THERAPY; THORACOSCOPY; TREATMENT FAILURE;

EID: 84951990352     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2015.16840     Document Type: Article

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