Physiologic responsiveness should guide entry into randomized controlled trials

American Journal of Respiratory and Critical Care Medicine

Volumn 192, Issue 12, 2015, Pages 1416-1419

  Goligher, Ewan C ^a,b   Kavanagh, Brian P ^a,b,c   Rubenfeld, Gordon D ^a,b,d,e   Ferguson, Niall D ^a,b,e  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c Department of Anesthesia ^*  (Canada)

^d SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT RESPIRATORY DISTRESS SYNDROME; ATELECTASIS; EFFECT SIZE; HUMAN; INTENSIVE CARE; MORTALITY; OUTCOME ASSESSMENT; PATIENT SELECTION; PERSONALIZED MEDICINE; PHYSIOLOGY; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SAMPLE SIZE; STUDY DESIGN; SURVIVAL; TIDAL VOLUME; TISSUE OXYGENATION; VENTILATOR INDUCED LUNG INJURY; LUNG FUNCTION TEST; PATHOPHYSIOLOGY; RESPIRATORY DISTRESS SYNDROME, ADULT; STATISTICS AND NUMERICAL DATA;

CRITICAL CARE; HUMANS; PATIENT SELECTION; POSITIVE-PRESSURE RESPIRATION; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESPIRATORY DISTRESS SYNDROME, ADULT; RESPIRATORY FUNCTION TESTS; TIDAL VOLUME;

EID: 84951924668     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201410-1832CP     Document Type: Review

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