Efficacy of duloxetine in chronic low back pain with a neuropathic component: A randomized, double-blind, placebo-controlled crossover trial

Anesthesiology

Volumn 124, Issue 1, 2016, Pages 150-158

  Schukro, Regina P ^a   Oehmke, Matthias J ^b   Geroldinger, Angelika ^a   Heinze, Georg ^a   Kress, Hans Georg ^a   Pramhas, Sibylle ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b Chirurgische Abteilung   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DIPYRONE; DULOXETINE; PLACEBO; TRAMADOL; ANALGESIC AGENT;

ADULT; ANALGESIA; ARTICLE; CLINICAL ASSESSMENT; CONSTIPATION; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIARRHEA; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG DOSE TITRATION; DRUG EFFICACY; FATIGUE; FEMALE; HUMAN; INSOMNIA; INTENTION TO TREAT ANALYSIS; LEG PAIN; LOSS OF APPETITE; LOW BACK PAIN; MAJOR CLINICAL STUDY; MALE; NAUSEA; NEUROPATHIC PAIN; OUTCOME ASSESSMENT; PAIN; PAIN ASSESSMENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SWEATING; TREATMENT DURATION; VISUAL ANALOG SCALE; XEROSTOMIA; CHRONIC DISEASE; COMPLICATION; MIDDLE AGED; NEURALGIA; TREATMENT OUTCOME;

ANALGESICS; CHRONIC DISEASE; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; DULOXETINE HYDROCHLORIDE; FEMALE; HUMANS; LOW BACK PAIN; MALE; MIDDLE AGED; NEURALGIA; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84951906285     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0000000000000902     Document Type: Article

References (39)

1. Andersson GB, Epidemiological features of chronic low-back pain. Lancet 1999 354 581 5
2. Balagué F, Mannion AF, Pellisé F, Cedraschi C, Non-specific low back pain. Lancet 2012 379 482 91
3. Deyo RA, Weinstein JN, Low back pain. N Engl J Med 2001 344 363 70
4. Freynhagen R, Baron R, Gockel U, Tölle TR, painDETECT: A new screening questionnaire to identify neuropathic components in patients with back pain. Curr Med Res Opin 2006 22 1911 20
5. Schmidt CO, Schweikert B, Wenig CM, Schmidt U, Gockel U, Freynhagen R, Tölle TR, Baron R, Kohlmann T, Modelling the prevalence and cost of back pain with neuropathic components in the general population. Eur J Pain 2009 13 1030 5
6. Tarulli AW, Raynor EM, Lumbosacral radiculopathy. Neurol Clin 2007 25 387 405
7. Bruegger A, On vertebral, radicular and pseudoradicular syndromes. On the differential diagnosis of rheumatological and neurological diseases. I. Vertebral syndromes. Doc Geigy Acta Rheumatol 1960 18 1 139
8. Sutter M, An attempt to define radicular and pseudoradicular syndromes (author's transl). Schweiz Rundsch Med Prax 1974 63 842 5
9. Freynhagen R, Rolke R, Baron R, Tölle TR, Rutjes AK, Schu S, Treede RD, Pseudoradicular and radicular low-back pain-A disease continuum rather than different entities? Answers from quantitative sensory testing. Pain 2008 135 65 74
10. Kaki AM, El-Yaski AZ, Youseif E, Identifying neuropathic pain among patients with chronic low-back pain: Use of the Leeds Assessment of Neuropathic Symptoms and Signs pain scale. Reg Anesth Pain Med 2005 30 422 8
11. Bennett MI, Attal N, Backonja MM, Baron R, Bouhassira D, Freynhagen R, Scholz J, Tölle TR, Wittchen HU, Jensen TS, Using screening tools to identify neuropathic pain. Pain 2007 127 199 203
12. Freynhagen R, Baron R, The evaluation of neuropathic components in low back pain. Curr Pain Headache Rep 2009 13 185 90
13. Baron R, Martin-Mola E, Müller M, Dubois C, Falke D, Steigerwald I, Effectiveness and safety of tapentadol prolonged release (PR) versus a combination of tapentadol PR and pregabalin for the management of severe, chronic low back pain with a neuropathic component: A randomized, double-blind, phase 3b study. Pain Pract 2015 15 455 70
14. Cohen SP, Argoff CE, Carragee EJ, Management of low back pain. BMJ 2008 337 a2718
15. Chou R, Qaseem A, Snow V, Casey D, Cross JT Jr, Shekelle P, Owens DK, Clinical Efficacy Assessment Subcommittee of the American College of Physicians; American College of Physicians; American Pain Society Low Back Pain Guidelines Panel Diagnosis and treatment of low back pain: A joint clinical practice guideline from the American College of Physicians and the American Pain Society. Ann Intern Med 2007 147 478 91
16. Dworkin RH, O'Connor AB, Backonja M, Farrar JT, Finnerup NB, Jensen TS, Kalso EA, Loeser JD, Miaskowski C, Nurmikko TJ, Portenoy RK, Rice AS, Stacey BR, Treede RD, Turk DC, Wallace MS, Pharmacologic management of neuropathic pain: Evidence-based recommendations. Pain 2007 132 237 51
17. Nemeroff CB, Schatzberg AF, Goldstein DJ, Detke MJ, Mallinckrodt C, Lu Y, Tran PV, Duloxetine for the treatment of major depressive disorder. Psychopharmacol Bull 2002 36 106 32
18. Detke MJ, Lu Y, Goldstein DJ, Hayes JR, Demitrack MA, Duloxetine, 60 mg once daily, for major depressive disorder: A randomized double-blind placebo-controlled trial. J Clin Psychiatry 2002 63 308 15
19. Detke MJ, Lu Y, Goldstein DJ, McNamara RK, Demitrack MA, Duloxetine 60 mg once daily dosing versus placebo in the acute treatment of major depression. J Psychiatr Res 2002 36 383 90
20. Allgulander C, Hartford J, Russell J, Ball S, Erickson J, Raskin J, Rynn M, Pharmacotherapy of generalized anxiety disorder: Results of duloxetine treatment from a pooled analysis of three clinical trials. Curr Med Res Opin 2007 23 1245 52
21. Sultan A, Gaskell H, Derry S, Moore RA, Duloxetine for painful diabetic neuropathy and fibromyalgia pain: Systematic review of randomised trials. BMC Neurol 2008 8 29
22. Goldstein DJ, Lu Y, Detke MJ, Lee TC, Iyengar S, Duloxetine vs. placebo in patients with painful diabetic neuropathy. Pain 2005 116 109 18
23. Raskin J, Pritchett YL, Wang F, D'Souza DN, Waninger AL, Iyengar S, Wernicke JF, A double-blind, randomized multicenter trial comparing duloxetine with placebo in the management of diabetic peripheral neuropathic pain. Pain Med 2005 6 346 56
24. Wernicke JF, Pritchett YL, D'Souza DN, Waninger A, Tran P, Iyengar S, Raskin J, A randomized controlled trial of duloxetine in diabetic peripheral neuropathic pain. Neurology 2006 67 1411 20
25. Skljarevski V, Desaiah D, Liu-Seifert H, Zhang Q, Chappell AS, Detke MJ, Iyengar S, Atkinson JH, Backonja M, Efficacy and safety of duloxetine in patients with chronic low back pain. Spine (Phila Pa 1976) 2010 35 E578 85
26. Skljarevski V, Ossanna M, Liu-Seifert H, Zhang Q, Chappell A, Iyengar S, Detke M, Backonja M, A double-blind, randomized trial of duloxetine versus placebo in the management of chronic low back pain. Eur J Neurol 2009 16 1041 8
27. Skljarevski V, Zhang S, Chappell AS, Walker DJ, Murray I, Backonja M, Maintenance of effect of duloxetine in patients with chronic low back pain: A 41-week uncontrolled, dose-blinded study. Pain Med 2010 11 648 57
28. Skljarevski V, Zhang S, Desaiah D, Alaka KJ, Palacios S, Miazgowski T, Patrick K, Duloxetine versus placebo in patients with chronic low back pain: A 12-week, fixed-dose, randomized, double-blind trial. J Pain 2010 11 1282 90
29. Khoromi S, Cui L, Nackers L, Max MB, Morphine, nortriptyline and their combination vs. placebo in patients with chronic lumbar root pain. Pain 2007 130 66 75
30. McHorney CA, Ware JE Jr, Raczek AE, The MOS 36-Item Short-Form Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. Med Care 1993 31 247 63
31. Farrar JT, Young JP Jr, LaMoreaux L, Werth JL, Poole RM, Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale. Pain 2001 94 149 58
32. Dworkin RH, Turk DC, McDermott MP, Peirce-Sandner S, Burke LB, Cowan P, Farrar JT, Hertz S, Raja SN, Rappaport BA, Rauschkolb C, Sampaio C, Interpreting the clinical importance of group differences in chronic pain clinical trials: IMMPACT recommendations. Pain 2009 146 238 44
33. O'Connor AB, Neuropathic pain: Quality-of-life impact, costs and cost effectiveness of therapy. Pharmacoeconomics 2009 27 95 112
34. Morlion B, Pharmacotherapy of low back pain: Targeting nociceptive and neuropathic pain components. Curr Med Res Opin 2011 27 11 33
35. Atkinson JH, Slater MA, Wahlgren DR, Williams RA, Zisook S, Pruitt SD, Epping-Jordan JE, Patterson TL, Grant I, Abramson I, Garfin SR, Effects of noradrenergic and serotonergic antidepressants on chronic low back pain intensity. Pain 1999 83 137 45
36. Khoromi S, Patsalides A, Parada S, Salehi V, Meegan JM, Max MB, Topiramate in chronic lumbar radicular pain. J Pain 2005 6 829 36
37. Cohen SP, Hanling S, Bicket MC, White RL, Veizi E, Kurihara C, Zhao Z, Hayek S, Guthmiller KB, Griffith SR, Gordin V, White MA, Vorobeychik Y, Pasquina PF, Epidural steroid injections compared with gabapentin for lumbosacral radicular pain: Multicenter randomized double blind comparative efficacy study. BMJ 2015 350 h1748
38. Vanelderen P, Van Zundert J, Kozicz T, Puylaert M, De Vooght P, Mestrum R, Heylen R, Roubos E, Vissers K, Effect of minocycline on lumbar radicular neuropathic pain: A randomized, placebo-controlled, double-blind clinical trial with amitriptyline as a comparator. A nesthesiology 2015 122 399 406
39. Steigerwald I, Müller M, Davies A, Samper D, Sabatowski R, Baron R, Rozenberg S, Szczepanska-Szerej A, Gatti A, Kress HG, Effectiveness and safety of tapentadol prolonged release for severe, chronic low back pain with or without a neuropathic pain component: Results of an open-label, phase 3b study. Curr Med Res Opin 2012 28 911 36