Internet-delivered acceptance-based behaviour therapy for generalized anxiety disorder: A randomized controlled trial

Behaviour Research and Therapy

Volumn 77, Issue , 2016, Pages 86-95

  Dahlin, Mats ^a   Andersson, Gerhard ^b,c   Magnusson, Kristoffer ^c   Johansson, Tomas ^e   Sjögren, Johan ^e   Håkansson, Andreas ^e   Pettersson, Magnus ^e   Kadowaki, Åsa ^f   Cuijpers, Pim ^g,h   Carlbring, Per ^d  

^a Linköping University ^*  (Sweden)

^b LINKÖPING UNIVERSITY   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

^d STOCKHOLM UNIVERSITY   (Sweden)

^e UMEÅ UNIVERSITY   (Sweden)

^f Operations and Specialty Surgery Center   (Sweden)

^g VU UNIVERSITY AMSTERDAM   (Netherlands)

^h UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Acceptance; Generalized anxiety disorder; Internet based behaviour therapy; Mindfulness; Randomized controlled trial

Indexed keywords

ADULT; ARTICLE; BEHAVIOR THERAPY; CONTROLLED STUDY; DEPRESSION; FEMALE; FOLLOW UP; GENERALIZED ANXIETY DISORDER; HUMAN; INTERNET; MAJOR CLINICAL STUDY; MALE; PATIENT DROPOUTS; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; ANXIETY DISORDERS; BEHAVIOR; CASE CONTROL STUDY; COGNITIVE THERAPY; COMPUTER ASSISTED THERAPY; MINDFULNESS; PROCEDURES; PSYCHOLOGY; SWEDEN;

ADULT; ANXIETY DISORDERS; BEHAVIOR; BEHAVIOR THERAPY; CASE-CONTROL STUDIES; COGNITIVE THERAPY; DEPRESSION; FEMALE; HUMANS; INTERNET; MALE; MINDFULNESS; QUALITY OF LIFE; SWEDEN; THERAPY, COMPUTER-ASSISTED;

EID: 84951821455     PISSN: 00057967     EISSN: 1873622X     Source Type: Journal    
DOI: 10.1016/j.brat.2015.12.007     Document Type: Article

References (58)

1. Algina J., Keselman H.J., Penfield R.D. Confidence interval coverage for Cohen's effect size statistic. Educational and Psychological Measurement 2006, 66:945-960. 10.1177/0013164406288161.
2. American Psychiatric Association Desk reference to the diagnostic criteria from DSM-5 2013, American Psychiatric Press, Washington.
3. Andersson G. Using the internet to provide cognitive behaviour therapy. Behaviour Research and Therapy 2009, 47:175-180. 10.1016/j.brat.2009.01.010.
4. Andersson G. The internet and CBT: A clinical guide 2014, CRC Press, Boca Raton.
5. Andersson G., Cuijpers P., Carlbring P., Riper H., Hedman E. Internet-based vs. face-to-face cognitive behaviour therapy for psychiatric and somatic disorders: a systematic review and meta-analysis. World Psychiatry 2014, 13:288-295. 10.1002/wps.20151.
6. Andersson G., Paxling B., Roch-Norlund P., Östman G., Norgren A., Almlöv J., et al. Internet-based psychodynamic vs. cognitive behavioural guided self-help for generalized anxiety disorder: a randomised controlled trial. Psychotherapy and Psychosomatics 2012, 81:344-355. 10.1159/000339371.
7. Bates D., Maechler M., Bolker B., Walker S. Linear mixed-effects models using Eigen and S4 lme4, R package version 1.1-7. http://CRAN.R-project.org/package=lme4.
8. Beck A.T., Epstein N., Brown G., Steer R. An inventory for measuring clinical anxiety. Psychometric properties. Journal of Consulting and Clinical Psychology 1988, 56:893-897. 10.1037/0022-006X.56.6.893.
9. Behar E., Alcaine O., Zuellig A.R., Borkovec T.D. Screening for generalized anxiety disorder using the Penn State Worry Questionnaire: a receiver operating characteristic analysis. Journal of Behavior Therapy and Experimental Psychiatry 2003, 34:25-43. 10.1016/S0005-7916(03)00004-1.
10. Buhrman M., Skoglund A., Husell J., Bergström K., Gordh T., Hursti T., et al. Guided internet-delivered acceptance and commitment therapy for chronic pain patients: a randomized controlled trial. Behaviour Research and Therapy 2013, 51:307-315. 10.1016/j.brat.2013.02.010.
11. Carlbring P., Brunt S., Bohman S., Austin D., Richards J.C., Öst L.-G., et al. Internet vs. paper and pencil administration of questionnaires commonly used in panic/agoraphobia research. Computers in Human Behavior 2007, 23:1421-1434. 10.1016/j.chb.2005.05.002.
12. Carlbring P., Hägglund M., Luthström A., Dahlin M., Kadowaki Å., Vernmark K., et al. Internet-based behavioral activation and acceptance-based treatment for depression: a randomized controlled trial. Journal of Affective Disorders 2013, 148:331-337. 10.1016/j.jad.2012.12.020.
13. Christensen H., Mackinnon A.J., Batterham P.J., O'Dea B., Guastella A.J., Griffiths K.M., et al. The effectiveness of an online e-health application compared to attention placebo or sertraline in the treatment of generalised anxiety disorder. Internet Interventions 2014, 1:169-174. http://dx.doi.org/10.1016/j.invent.2014.08.002.
14. Cuijpers P., Sijbrandij M., Koole S., Huibers M., Berking M., Andersson G. Psychological treatment of generalized anxiety disorder: a meta-analysis. Clinical Psychology Review 2014, 34:130-140.
15. Cumming G. Understanding the new statistics: Effect sizes, confidence intervals, and meta-analysis 2012, Routledge, New York.
16. First M.B., Gibbon M., Spitzer R.L., Williams J.B.W. Structured clinical interview for DSM-IV Axis I Disorders (SCID-I) 1997, American Psychiatric Press, Washington, D.C.
17. Fledderus M., Bohlmeijer E.T., Pieterse M.E., Schreurs K.M. Acceptance and commitment therapy as guided self-help for psychological distress and positive mental health: a randomized controlled trial. Psychological Medicine 2012, 42:485-495.
18. Frisch M.B., Cornell J., Villanueva M., Retzlaff P.J. Clinical validation of the quality of life inventory: a measure of life satisfaction for use in treatment planning and outcome assessment. Psychological Assessment 1992, 4:92-101. 10.1037/1040-3590.4.1.92.
19. Gillis M.M., Haaga D.A.F., Ford G.T. Normative values for the beck anxiety inventory, fear questionnaire, penn state worry questionnaire, and social Phobia and anxiety inventory. Psychological Assessment 1995, 7:450-455. 10.1037/1040-3590.7.4.450.
20. Goldstein H. Multilevel statistical models 2011, Wiley, Chichester. 4 ed.
21. Hayes-Skelton S.A., Roemer L., Orsillo S.M. A randomized clinical trial comparing an acceptance-based behavior therapy to applied relaxation for generalized anxiety disorder. Journal of Consulting and Clinical Psychology 2013, 81(5):761-773. 10.1037/a0032871.
22. Hayes S.C., Luoma J.B., Bond F.W., Masuda A., Lillis J. Acceptance and commitment therapy: model, processes and outcomes. Behaviour Research and Therapy 2006, 44:1-25. 10.1016/j.brat.2005.06.006.
23. Hayes S.C., Wilson K.G., Strosahl K., Gifford E.V., Follette V.M. Experiential avoidance and behavioral disorders: a functional dimensional approach to diagnosis and treatment. Journal of Consulting and Clinical Psychology 1996, 64:1152-1168. 10.1037/0022-006X.64.6.1152.
24. Hedeker D., Gibbons R.D. Application of random-effects pattern-mixture models for missing data in longitudinal studies. Psychological Methods 1997, 2(1):64-78. 10.1037/1082-989X.2.1.64.
25. Hedeker D., Gibbons R.D. Longitudinal data analysis 2006, John Wiley, Chichester.
26. Heimberg R.G., Turk C.L., Mennin D.S. Generalized anxiety disorder. Advances in research and practice 2004, The Guilford Press, New York.
27. Hesser H., Gustafsson T., Lundén C., Henriksson O., Fattahi K., Zetterqvist Westin E.,J., et al. A randomized controlled trial of Internet-delivered cognitive behavior therapy and acceptance and commitment therapy in the treatment of tinnitus. Journal of Consulting and Clinical Psychology 2012, 80:649-661. 10.1037/a0027021.
28. Hoffman D.L., Dukes E.M., Wittchen H.-U. Human and economic burden of generalized anxiety disorder. Depression and Anxiety 2008, 25:72-90. 10.1002/da.20257.
29. Hofmann S.G., Asmundson G.J.G. Acceptance and mindfulness-based therapy: new wave or old hat?. Clinical Psychology Review 2008, 28:1-16. 10.1016/j.cpr.2007.09.003.
30. Hofmann S.G., Wu J.Q., Boettcher H. Effect of cognitive-behavioral therapy for anxiety disorders on quality of life: a meta-analysis. Journal of Consulting and Clinical Psychology 2014, 82:375-391. 10.1037/a0035491.
31. Jacobson N.S., Truax P. Clinical significance: a statistical approach to defining meaningful change in psychotherapy research. Journal of Consulting and Clinical Psychology 1991, 59:12-19. 10.1037/0022-006X.59.1.12.
32. Klein B., Meyer D., Austin D.W., Kyrios M. Anxiety online: a virtual clinic: preliminary outcomes following completion of five fully automated treatment programs for anxiety disorders and symptoms. Journal of Medical Internet Research 2011, 13:e89. 10.2196/jmir.1918.
33. Kroenke K., Spitzer R.L., Williams J.B. The PHQ-9: validity of a brief depression severity measure. Journal of General Internal Medicine 2001, 16:606-613. doi: jgi01114 [pii].
34. Lappalainen P., Granlund A., Siltanen S., Ahonen S., Vitikainen M., Tolvanen A., et al. act internet-based vs face-to-face? a randomized controlled trial of two ways to deliver acceptance and commitment therapy for depressive symptoms: an 18-month follow-up. Behaviour Research and Therapy 2014, 61:43-54. 10.1016/j.brat.2014.07.006.
35. Lindner P., Andersson G., Öst L.-G., Carlbring P. Validation of the Internet-administered Quality of Life Inventory (QOLI) in different psychiatric conditions. Cognitive Behaviour Therapy 2013, 42:315-327. 10.1080/16506073.2013.806584.
36. Mewton L., Wong N., Andrews G. The effectiveness of internet cognitive behavioural therapy for generalized anxiety disorder in clinical practice. Depression and Anxiety 2012, 29(10):843-849. 10.1002/da.21995.
37. Meyer T.J., Miller M.L., Metzger R.L., Borkovec T.D. Development and validation of the penn state worry questionnaire. Behaviour Research and Therapy 1990, 28:487-495. 10.1016/0005-7967(90)90135-6.
38. Molenberghs G., Thijs H., Jansen I., Beunckens C., Kenward M.G., Mallinckrodt C., et al. Analyzing incomplete longitudinal clinical trial data. Biostatistics 2004, 5:445-464. 10.1093/biostatistics/kxh001.
39. Newman M.G., Zuellig A.R., Kachin K.E., Constantino M.J., Przeworski A., Erickson T., et al. Preliminary reliability and validity of the GAD-Q-IV: a revised self-report diagnostic measure of generalized anxiety disorder. Behavior Therapy 2002, 33:215-233. 10.1016/S0005-7894(02)80026-0.
40. Öst L.-G. The efficacy of Acceptance and Commitment Therapy: an updated systematic review and meta-analysis. Behaviour Research and Therapy 2014, 61:105-121. 10.1016/j.brat.2014.07.018.
41. Paxling B., Almlöv J., Dahlin M., Carlbring P., Breitholtz E., Eriksson T., et al. Guided internet-delivered cognitive behavior therapy for generalized anxiety disorder: a randomized controlled trial. Cognitive Behaviour Therapy 2011, 40:159-173. 10.1080/16506073.2011.576699.
42. Paxling B., Lundgren S., Norman A., Almlöv J., Carlbring P., Cuijpers P., et al. Therapist behaviours in Internet-delivered cognitive behaviour therapy: analyses of e-mail correspondence in the treatment of generalized anxiety disorder. Behavioural and Cognitive Psychotherapy 2013, 41:280-289. 10.1017/S1352465812000240.
43. Posternak M.A., Zimmerman M. Therapeutic effect of follow-up assessments on antidepressant and placebo response rates in antidepressant efficacy trials: meta-analysis. British Journal of Psychiatry 2007, 190:287-292. 10.1192/bjp.bp.106.028555.
44. R Core Team R: A Language and Environment for statistical computing 2013, R Foundation for Statistical Computing, Vienna. http://www.R-project.org/.
45. Raudenbush S.W., Bryk A.S. Hierarchical linear models: Applications and data analysis methods 2002, Sage, Newbury Park, CA.
46. Revicki D.A., Travers K., Wyrwich K.W., Svedsater H., Locklear J., Mattera M.S., et al. Humanistic and economic burden of generalized anxiety disorder in North America and Europe. Journal of Affective Disorders 2012, 140(2):103-112. 10.1016/j.jad.2011.11.014.
47. Robinson E., Titov N., Andrews G., McIntyre K., Schwencke G., Solley K. Internet treatment for generalized anxiety disorder: a randomized controlled trial comparing clinician vs. technician assistance. PloS One 2010, 5:e10942. 10.1371/journal.pone.0010942.
48. Roemer L., Orsillo S.M. Expanding our conceptualization of and treatment for generalized anxiety disorder: Integrating mindfulness/acceptance-based approaches with existing cognitive-behavioral models. Clinical Psychology: Science and Practice 2002, 9:54-68. 10.1093/clipsy.9.1.54.
49. Roemer L., Orsillo S.M. An open trial of an acceptance-based behavior therapy for generalized anxiety disorder. Behavior Therapy 2007, 38:72-85. 10.1016/j.beth.2006.04.004.
50. Roemer L., Orsillo S.M., Salters-Pedneault K. Efficacy of an acceptance-based behavior therapy for generalized anxiety disorder: evaluation in a randomized controlled trial. Journal of Consulting and Clinical Psychology 2008, 76:1083-1089. 10.1037/a0012720.
51. Rozental A., Andersson G., Boettcher J., Ebert D., Cuijpers P., Knaevelsrud C., et al. Consensus statement on defining and measuring negative effects of Internet interventions. Internet Interventions 2014, 1:12-19. 10.1016/j.invent.2014.02.001.
52. Spitzer R.L., Kroenke K., Williams J.B., Lowe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Archives of Internal Medicine 2006, 166:1092-1097. 10.1001/archinte.166.10.1092.
53. Svanborg P., Åsberg M. A comparison between the Beck Depression Inventory (BDI) and the self-rating version of the Montgomery Asberg Depression Rating Scale (MADRS). Journal of Affective Disorders 2001, 64:203-216. 10.1016/S0165-0327(00)00242-1.
54. Titov N., Andrews G., Robinson E., Schwencke G., Johnston L., Solley K., et al. Clinician-assisted Internet-based treatment is effective for generalized anxiety disorder: randomized controlled trial. Australian and New Zealand Journal of Psychiatry 2009, 43:905-912. 10.1080/00048670903179269.
55. Titov N., Dear B.F., Andersson G. Internet-delivered psychotherapy for anxiety disorders and depression. Focus 2014, 12:299-308. 10.1176/appi.focus.12.3.299.
56. Tyrer P., Baldwin D. Generalised anxiety disorder. Lancet 2006, 368:2156-2166. 10.1016/S0140-6736(06)69865-6.
57. Waller G. Evidence-based treatment and therapist drift. Behaviour Research and Therapy 2009, 47:119-127. 10.1016/j.brat.2008.10.018.
58. Wolitzky-Taylor K.B., Arch J.J., Rosenfield D., Craske M.G. Moderators and non-specific predictors of treatment outcome for anxiety disorders: a comparison of cognitive behavioral therapy to acceptance and commitment therapy. Journal of Consulting and Clinical Psychology 2012, 80(5):786-799. 10.1037/a0029418.