Interleukin-1B signalling leads to increased survival of gastric carcinoma cells through a CREB-C/EBPβ-associated mechanism

Gastric Cancer

Volumn 19, Issue 1, 2016, Pages 74-84

  Resende, Carlos ^a,b   Regalo, Gonçalo ^b   Durães, Cecília ^a,b   Pinto, Marta Teixeira ^a,b   Wen, Xiaogang ^c   Figueiredo, Ceu ^a,b   Carneiro, Fátima ^a,b   Machado, José C ^a,b  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c Centro Hospitalar Vila Nova de Gaia/Espinho   (Portugal)

Author keywords

Gastric cancer; Genetic susceptibility; Helicobacter pylori; IL1B; Inflammation

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; CEBPB PROTEIN, HUMAN; CREB1 PROTEIN, HUMAN;

ARTICLE; CARCINOGENESIS; CARCINOMA CELL; CELL GROWTH; CELL SURVIVAL; CHORIOALLANTOIS; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN TISSUE; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STOMACH CARCINOMA; ANIMAL; CELL PROLIFERATION; CHICK EMBRYO; DRUG EFFECTS; GENETICS; HELICOBACTER INFECTION; METABOLISM; PATHOLOGY; STOMACH MUCOSA; STOMACH TUMOR; TUMOR CELL LINE;

ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHICK EMBRYO; CHORIOALLANTOIC MEMBRANE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GASTRIC MUCOSA; HELICOBACTER INFECTIONS; HUMANS; INTERLEUKIN-1BETA; MAP KINASE SIGNALING SYSTEM; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS;

EID: 84951569926     PISSN: 14363291     EISSN: 14363305     Source Type: Journal    
DOI: 10.1007/s10120-014-0448-x     Document Type: Article

References (34)

1. Parkin DM, Bray F, Ferlay J, et al. Global cancer statistics, 2002. CA Cancer J Clin. 2005;55:74–108.
2. Correa P. Human gastric carcinogenesis: a multistep and multifactorial process—First American Cancer Society Award Lecture on cancer epidemiology and prevention. Cancer Res. 1992;52:6735–40.
3. Crew KD, Neugut AI. Epidemiology of gastric cancer. World J Gastroenterol. 2006;12:354–62.
4. Milne AN, Carneiro F, O’Morain C, et al. Nature meets nurture: molecular genetics of gastric cancer. Hum Genet. 2009;126:615–28.
5. Resende C, Ristimäki A, Machado JC. Genetic and epigenetic alteration in gastric carcinogenesis. Helicobacter. 2010;15:34–9.
6. Amieva MR, El-Omar EM. Host-bacterial interactions in Helicobacter pylori infection. Gastroenterology. 2008;134:306–23.
7. El-Omar EM, Carrington M, Chow W-H, et al. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature. 2000;404:398–402.
8. Machado JC, Pharoah P, Sousa S, et al. Interleukin 1B and interleukin 1RN polymorphisms are associated with increased risk of gastric carcinoma. Gastroenterology. 2001;121:823–9.
9. Figueiredo C, Machado JC, Pharoah P, et al. Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma. J Natl Cancer Inst. 2002;94:1680–7.
10. Machado JC, Figueiredo C, Canedo P, et al. A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma. Gastroenterology. 2003;125:364–71.
11. Canedo P, Corso G, Pereira F, et al. The interferon gamma receptor 1 (IFNGR1) −56C/T gene polymorphism is associated with increased risk of early gastric carcinoma. Gut. 2008;57:1504–8.
12. Hwang I-R, Kodama T, Kikuchi S, et al. Effect of interleukin 1 polymorphisms on gastric mucosal interleukin 1β production in Helicobacter pylori infection. Gastroenterology. 2002;123:1793–803.
13. Tu S, Bhagat G, Cui G, et al. Overexpression of interleukin-1β induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. Cancer Cell. 2008;14:408–19.
14. Beales ILP, Calam J. Interleukin 1β and tumour necrosis factor α inhibit acid secretion in cultured rabbit parietal cells by multiple pathways. Gut. 1998;42:227–34.
15. Konturek P, Kania J, Konturek J, et al. H. pylori infection, atrophic gastritis, cytokines, gastrin, COX-2, PPAR gamma and impaired apoptosis in gastric carcinogenesis. Med Sci Monit 2003;9:SR53–66.
16. Beales I. Effect of interleukin-1beta on proliferation of gastric epithelial cells in culture. BMC Gastroenterol. 2002;2:7.
17. Yasunaga Y, Shinomura Y, Kanayama S, et al. Increased production of interleukin 1 beta and hepatocyte growth factor may contribute to foveolar hyperplasia in enlarged fold gastritis. Gut. 1996;39:787–94.
18. El-Omar EM, Rabkin CS, Gammon MD, et al. Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms. Gastroenterology. 2003;124:1193–201.
19. Newton K, Dixit VM. Signaling in innate immunity and inflammation. Cold Spring Harbor Perspect Biol. 2012;4:3.
20. Naumann M, Crabtree JE. Helicobacter pylori-induced epithelial cell signalling in gastric carcinogenesis. Trends Microbiol. 2004;12:29–36.
21. Kudo T, Lu H, Wu JY, et al. Pattern of transcription factor activation in Helicobacter pylori—infected Mongolian gerbils. Gastroenterology. 2007;132:1024–38.
22. Giltiay NV, Karakashian AA, Alimov AP, et al. Ceramide- and ERK-dependent pathway for the activation of CCAAT/enhancer binding protein by interleukin-1β in hepatocytes. J Lipid Res. 2005;46:2497–505.
23. Regalo G, Canedo P, Suriano G, et al. C/EBPbeta is over-expressed in gastric carcinogenesis and is associated with COX-2 expression. J Pathol. 2006;210:398–404.
24. Sankpal NV, Mayo MW, Powell SM. Transcriptional repression of TFF1 in gastric epithelial cells by CCAAT/enhancer binding protein-β. Biochim Biophys Acta 2005;1728:1–10.
25. Sankpal NV, Moskaluk CA, Hampton GM, et al. Overexpression of CEBPbeta correlates with decreased TFF1 in gastric cancer. Oncogene. 2006;25:643–9.
26. Zhao D. Protein kinase Cδ-mediated CREB activation regulates ghrelin-induced cyclooxygenase-2 expression and prostaglandin E2 production in human colonic epithelial cells. J Cell Biochem. 2007;102:1245–55.
27. Sun H, Chung WC, Ryu SH, et al. Cyclic AMP-responsive element binding protein- and nuclear factor-kappaB-regulated CXC chemokine gene expression in lung carcinogenesis. Cancer Prev Res (Phila). 2008;1:316–28.
28. Shankar DB, Cheng JC, Kinjo K, et al. The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia. Cancer Cell. 2005;7:351–62.
29. Seo HS, Liu DD, Bekele BN, et al. Cyclic AMP response element-binding protein overexpression: a feature associated with negative prognosis in never smokers with non-small cell lung cancer. Cancer Res. 2008;68:6065–73.
30. Aggarwal S, Kim SW, Ryu SH, et al. Growth suppression of lung cancer cells by targeting cyclic AMP response element-binding protein. Cancer Res. 2008;68:981–8.
31. Chhabra A, Fernando H, Watkins G, et al. Expression of transcription factor CREB1 in human breast cancer and its correlation with prognosis. Oncol Rep. 2007;18:953–8.
32. Niehof M, Manns MP, Trautwein C. CREB controls LAP/C/EBP beta transcription. Mol Cell Biol. 1997;17:3600–13.
33. Zhang JW, Klemm DJ, Vinson C, et al. Role of CREB in transcriptional regulation of CCAAT/enhancer-binding protein beta gene during adipogenesis. J Biol Chem. 2004;279:4471–8.
34. Chen L, Yang Q, Kong WQ, et al. MicroRNA-181b targets cAMP responsive element binding protein 1 in gastric adenocarcinomas. IUBMB Life. 2012;64:628–35.