Predictors for stroke and death in non-anticoagulated Asian patients with atrial fibrillation: The Fushimi AF Registry

PLoS ONE

Volumn 10, Issue 11, 2015, Pages

  Hamatani, Yasuhiro ^a   Yamashita, Yugo ^a   Esato, Masahiro ^b   Chun, Yeong Hwa ^b   Tsuji, Hikari ^c   Wada, Hiromichi ^a   Hasegawa, Koji ^a   Abe, Mitsuru ^a   Lip, Gregory Y H ^d,e   Masaharu, Akao ^a  

^a NATIONAL HOSPITAL ORGANIZATION KYOTO MEDICAL CENTER   (Japan)

^b Ijinkai Takeda General Hospital   (Japan)

^c Tsuji Clinic   (Japan)

^d UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^e AALBORG UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT;

AGE; AGED; ANEMIA; ARTICLE; ATRIAL FIBRILLATION; CARDIOVASCULAR DISEASE ASSESSMENT; CEREBROVASCULAR ACCIDENT; CHA2DS2 VASC SCORE; CHADS2 SCORE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DEATH; DISEASE REGISTRY; EMBOLISM; FEMALE; FOLLOW UP; HEART FAILURE; HUMAN; JAPANESE (PEOPLE); MAJOR CLINICAL STUDY; MALE; TRANSIENT ISCHEMIC ATTACK; UNDERWEIGHT; ASIAN CONTINENTAL ANCESTRY GROUP; COMPLICATION; INCIDENCE; ISCHEMIC ATTACK, TRANSIENT; JAPAN; MORTALITY; PROSPECTIVE STUDY; REGISTER; RENAL INSUFFICIENCY, CHRONIC; RISK ASSESSMENT; RISK FACTOR; STROKE;

AGED; ANTICOAGULANTS; ASIAN CONTINENTAL ANCESTRY GROUP; ATRIAL FIBRILLATION; DEATH; FEMALE; HEART FAILURE; HUMANS; INCIDENCE; ISCHEMIC ATTACK, TRANSIENT; JAPAN; MALE; PROSPECTIVE STUDIES; REGISTRIES; RENAL INSUFFICIENCY, CHRONIC; RISK ASSESSMENT; RISK FACTORS; STROKE;

EID: 84951310581     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0142394     Document Type: Article

References (38)

1. Inoue H, Fujiki A, Origasa H, Ogawa S, Okumura K, Kubota I, et al. Prevalence of atrial fibrillation in the general population of Japan: an analysis based on periodic health examination. Int J Cardiol. 2009 Oct 2; 137(2):102-7. doi: 10.1016/j.ijcard.2008.06.029 PMID: 18691774
2. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke. 1991 Aug; 22(8):983-8. PMID: 1866765
3. Benjamin EJ, Wolf PA, D'Agostino RB, Silbershatz H, Kannel WB, Levy D. Impact of atrial fibrillation on the risk of death: the Framingham Heart Study. Circulation. 1998 Sep 8; 98(10):946-52. PMID: 9737513
4. Lip GY. Stroke and bleeding risk assessment in atrial fibrillation: when, how, and why? Eur Heart J. 2013 Apr; 34(14):1041-9. doi: 10.1093/eurheartj/ehs435 PMID: 23257951
5. Gage BF, Waterman AD, Shannon W, Boechler M, Rich MW, Radford MJ. Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA. 2001 Jun 13; 285(22):2864-70. PMID: 11401607
6. Lip GY, Nieuwlaat R, Pisters R, Lane DA, Crijns HJ. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the euro heart survey on atrial fibrillation. Chest. 2010 Feb; 137(2):263-72. doi: 10.1378/chest.09-1584 PMID: 19762550
7. Akao M, Chun YH, Wada H, Esato M, Hashimoto T, Abe M, et al. Current status of clinical background of patients with atrial fibrillation in a community-based survey: the Fushimi AF Registry. J Cardiol. 2013 Apr; 61(4):260-6. doi: 10.1016/j.jjcc.2012.12.002 PMID: 23403369
8. Akao M, Chun YH, Esato M, Abe M, Tsuji H, Wada H, et al. Inappropriate Use of Oral Anticoagulants for Patients With Atrial Fibrillation. Circ J. 2014; 78(9):2166-2172. PMID: 24976391
9. Executive summary of the clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults. Arch Intern Med. 1998 Sep 28; 158(17):1855-67. PMID: 9759681
10. Nutritional anaemias. Report of a WHO scientific group. World Health Organ Tech Rep Ser. 1968; 405:5-37. PMID: 4975372
11. Marijon E, Le Heuzey JY, Connolly S, Yang S, Pogue J, Brueckmann M, et al. Causes of death and influencing factors in patients with atrial fibrillation: a competing-risk analysis from the randomized evaluation of long-term anticoagulant therapy study. Circulation. 2013 Nov 12; 128(20):2192-201. doi: 10.1161/CIRCULATIONAHA.112.000491 PMID: 24016454
12. Lip GY, Laroche C, Ioachim PM, Rasmussen LH, Vitali-Serdoz L, Petrescu L, et al. Prognosis and treatment of atrial fibrillation patients by European cardiologists: one year follow-up of the EURObservational Research Programme-Atrial Fibrillation General Registry Pilot Phase (EORP-AF Pilot registry). Eur Heart J. 2014 Dec 14; 35(47):3365-76. doi: 10.1093/eurheartj/ehu374 PMID: 25176940
13. Hart RG, Pearce LA, Aguilar MI. Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med. 2007 Jun 19; 146(12):857-67. PMID: 17577005
14. Patients with nonvalvular atrial fibrillation at low risk of stroke during treatment with aspirin: Stroke Prevention in Atrial Fibrillation III Study. The SPAF III Writing Committee for the Stroke Prevention in Atrial Fibrillation Investigators. JAMA. 1998 Apr 22-29; 279(16):1273-7. PMID: 9565007
15. Petersen P, Kastrup J, Helweg-Larsen S, Boysen G, Godtfredsen J. Risk factors for thromboembolic complications in chronic atrial fibrillation. The Copenhagen AFASAK study. Arch Intern Med. 1990 Apr; 150(4):819-21. PMID: 2183733
16. Lip GY, Frison L, Grind M. Effect of hypertension on anticoagulated patients with atrial fibrillation. Eur Heart J. 2007 Mar; 28(6):752-9. PMID: 17289744
17. Yang YM, Shao XH, Zhu J, Zhang H, Liu Y, Gao X, et al. Risk factors and incidence of stroke and MACE in Chinese atrial fibrillation patients presenting to emergency departments: a national wide database analysis. Int J Cardiol. 2014 May 1; 173(2):242-7. doi: 10.1016/j.ijcard.2014.02.040 PMID: 24630382
18. Inoue H, Atarashi H, Okumura K, Yamashita T, Origasa H, Kumagai N, et al. Impact of gender on the prognosis of patients with nonvalvular atrial fibrillation. Am J Cardiol. 2014 Mar 15; 113(6):957-62. doi: 10.1016/j.amjcard.2013.11.057 PMID: 24461771
19. Horwich TB, Fonarow GC, Hamilton MA, MacLellan WR, Borenstein J. Anemia is associated with worse symptoms, greater impairment in functional capacity and a significant increase in mortality in patients with advanced heart failure. J Am Coll Cardiol. 2002 Jun 5; 39(11):1780-6. PMID: 12039491
20. Muzzarelli S, Pfisterer M. Anemia as independent predictor of major events in elderly patients with chronic angina. Am Heart J. 2006 Nov; 152(5):991-6. PMID: 17070178
21. Vaglio J, Safley DM, Rahman M, Kosiborod M, Jones P, Thompson R, et al. Relation of anemia at discharge to survival after acute coronary syndromes. Am J Cardiol. 2005 Aug 15; 96(4):496-9. PMID: 16098299
22. Sharma S, Gage BF, Deych E, Rich MW. Anemia: an independent predictor of death and hospitalizations among elderly patients with atrial fibrillation. Am Heart J. 2009 Jun; 157(6):1057-63. doi: 10.1016/ j.ahj.2009.03.009 PMID: 19464417
23. Puurunen M, Kiviniemi T, Nammas W, Schlitt A, Rubboli A, Nyman K, et al. Impact of anaemia on clinical outcome in patients with atrial fibrillation undergoing percutaneous coronary intervention: insights from the AFCAS registry. BMJ Open. 2014; 4(5):e004700. doi: 10.1136/bmjopen-2013-004700 PMID: 24823675
24. Zeng WT, Sun XT, Tang K, Mei WY, Liu LJ, Xu Q, et al. Risk of thromboembolic events in atrial fibrillation with chronic kidney disease. Stroke. 2015 Jan; 46(1):157-63. doi: 10.1161/STROKEAHA.114. 006881 PMID: 25424480
25. Piccini JP, Stevens SR, Chang Y, Singer DE, Lokhnygina Y, Go AS, et al. Renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R (2)CHADS(2) index in the ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation) and ATRIA (AnTicoagulation and Risk factors In Atrial fibrillation) study cohorts. Circulation. 2013 Jan 15; 127(2):224-32. doi: 10.1161/CIRCULATIONAHA.112.107128 PMID: 23212720
26. Go AS, Fang MC, Udaltsova N, Chang Y, Pomernacki NK, Borowsky L, et al. Impact of proteinuria and glomerular filtration rate on risk of thromboembolism in atrial fibrillation: the anticoagulation and risk factors in atrial fibrillation (ATRIA) study. Circulation. 2009 Mar 17; 119(10):1363-9. doi: 10.1161/CIRCULATIONAHA.108.816082 PMID: 19255343
27. Banerjee A, Fauchier L, Vourc'h P, Andres CR, Taillandier S, Halimi JM, et al. Renal impairment and ischemic stroke risk assessment in patients with atrial fibrillation: the Loire Valley Atrial Fibrillation Project. J Am Coll Cardiol. 2013 May 21; 61(20):2079-87. doi: 10.1016/j.jacc.2013.02.035 PMID: 23524209
28. Nakagawa K, Hirai T, Takashima S, Fukuda N, Ohara K, Sasahara E, et al. Chronic kidney disease and CHADS(2) score independently predict cardiovascular events and mortality in patients with nonvalvular atrial fibrillation. Am J Cardiol. 2011 Mar 15; 107(6):912-6. doi: 10.1016/j.amjcard.2010.10.074 PMID: 21247518
29. Guo Y, Wang H, Zhao X, Zhang Y, Zhang D, Ma J, et al. Relation of renal dysfunction to the increased risk of stroke and death in female patients with atrial fibrillation. Int J Cardiol. 2013 Sep 30; 168 (2):1502-8. doi: 10.1016/j.ijcard.2012.12.099 PMID: 23375056
30. Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004 Sep 23; 351(13):1296-305. PMID: 15385656
31. Badheka AO, Rathod A, Kizilbash MA, Garg N, Mohamad T, Afonso L, et al. Influence of obesity on outcomes in atrial fibrillation: yet another obesity paradox. Am J Med. 2010 Jul; 123(7):646-51. doi: 10.1016/j.amjmed.2009.11.026 PMID: 20609687
32. Ardestani A, Hoffman HJ, Cooper HA. Obesity and outcomes among patients with established atrial fibrillation. Am J Cardiol. 2010 Aug 1; 106(3):369-73. doi: 10.1016/j.amjcard.2010.03.036 PMID: 20643247
33. Wang J, Yang YM, Zhu J, Zhang H, Shao XH, Tian L, et al. Overweight is associated with improved survival and outcomes in patients with atrial fibrillation. Clin Res Cardiol. 2014 Jul; 103(7):533-42. doi: 10.1007/s00392-014-0681-7 PMID: 24535378
34. Overvad TF, Rasmussen LH, Skjoth F, Overvad K, Lip GY, Larsen TB. Body mass index and adverse events in patients with incident atrial fibrillation. Am J Med. 2013 Jul; 126(7):640.e9-17.
35. Hamatani Y, Ogawa H, Uozumi R, Iguchi M, Yamashita Y, Esato M, et al. Low Body Weight Is Associated With the Incidence of Stroke in Atrial Fibrillation Patients- Insight From the Fushimi AF Registry. Circ J. 2015 Apr 24; 79(5):1009-17. doi: 10.1253/circj.CJ-14-1245 PMID: 25740669
36. Pathak RK, Middeldorp ME, Meredith M, Mehta AB, Mahajan R, Wong CX, et al. Long-Term Effect of Goal Directed Weight Management in an Atrial Fibrillation Cohort: A Long-term Follow-Up StudY (LEGACY Study). J Am Coll Cardiol. 2015 Mar 26; 65(20):2159-69. doi: 10.1016/j.jacc.2015.03.002 PMID: 25792361
37. Kakkar AK, Mueller I, Bassand JP, Fitzmaurice DA, Goldhaber SZ, Goto S, et al. Risk profiles and antithrombotic treatment of patients newly diagnosed with atrial fibrillation at risk of stroke: perspectives from the international, observational, prospective GARFIELD registry. PLoS One. 2013; 8(5):e63479. doi: 10.1371/journal.pone.0063479 PMID: 23704912
38. Ogilvie IM, Newton N, Welner SA, Cowell W, Lip GY. Underuse of oral anticoagulants in atrial fibrillation: a systematic review. Am J Med. 2010 Jul; 123(7):638-45 e4. doi: 10.1016/j.amjmed.2009.11.025 PMID: 20609686