Genome-Edited Human Pluripotent Stem Cell-Derived Macrophages as a Model of Reverse Cholesterol Transport-Brief Report

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 36, Issue 1, 2016, Pages 15-18

  Gupta, Rajat M ^a,b   Meissner, Torsten B ^a   Cowan, Chad A ^a   Musunuru, Kiran ^a,b  

^a HARVARD UNIVERSITY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

cell differentiation; cholesterol; genetics; macrophages; stem cells

Indexed keywords

ABC TRANSPORTER A1; APOLIPOPROTEIN A1; CD14 ANTIGEN; CD68 ANTIGEN; INTERLEUKIN 1BETA; INTERLEUKIN 8; RANTES; UNCLASSIFIED DRUG; ABCA1 PROTEIN, HUMAN; APOA1 PROTEIN, HUMAN; AUTACOID; CHOLESTEROL; CRISPR ASSOCIATED PROTEIN; CYTOKINE;

ARTICLE; CELL CLONE; CHOLESTEROL TRANSPORT; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; FRAMESHIFT MUTATION; GENE SEQUENCE; GENETIC PROCEDURES; HOMOZYGOTE; HUMAN; HUMAN CELL; MACROPHAGE; PLURIPOTENT STEM CELL; PLURIPOTENT STEM CELL DERIVED MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE; CELL DIFFERENTIATION; CELL LINE; CRISPR CAS SYSTEM; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; HUMAN GENOME; INDEL MUTATION; METABOLISM; PHENOTYPE; TRANSPORT AT THE CELLULAR LEVEL;

APOLIPOPROTEIN A-I; ATP BINDING CASSETTE TRANSPORTER 1; BIOLOGICAL TRANSPORT; CELL DIFFERENTIATION; CELL LINE; CHOLESTEROL; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; CYTOKINES; FRAMESHIFT MUTATION; GENE EXPRESSION REGULATION; GENOME, HUMAN; GENOTYPE; HUMANS; INDEL MUTATION; INFLAMMATION MEDIATORS; MACROPHAGES; PHENOTYPE; PLURIPOTENT STEM CELLS;

EID: 84951296027     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.115.305956     Document Type: Article

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