Pivotal role for the visceral fat compartment in the release of persistent organic pollutants during weight loss

Journal of Clinical Endocrinology and Metabolism

Volumn 100, Issue 12, 2015, Pages 4463-4471

  Dirinck, E ^a   Dirtu, A C ^a   Jorens, P G ^a   Malarvannan, G ^a   Covaci, A ^a   Van Gaal, L F ^a  

^a ANTWERP UNIVERSITY HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

POLYCHLORINATED BIPHENYL; POLLUTANT;

ABDOMINAL FAT; ABDOMINAL OBESITY; ADULT; ANTHROPOMETRY; ARTICLE; BARIATRIC SURGERY; BLOOD LEVEL; BLOOD SAMPLING; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORRELATION ANALYSIS; COUNSELING; FEMALE; FOLLOW UP; HUMAN; INTRAABDOMINAL FAT; PERSISTENT ORGANIC POLLUTANT; PRIORITY JOURNAL; WEIGHT REDUCTION; BLOOD; BODY MASS; DIET THERAPY; METABOLISM; MIDDLE AGED; OBESITY; POLLUTANT; PROSPECTIVE STUDY; SUBCUTANEOUS FAT;

ABDOMINAL FAT; ADIPOSITY; ADULT; ANTHROPOMETRY; BARIATRIC SURGERY; BODY MASS INDEX; ENVIRONMENTAL POLLUTANTS; FEMALE; HUMANS; INTRA-ABDOMINAL FAT; MIDDLE AGED; OBESITY; OVERWEIGHT; POLYCHLORINATED BIPHENYLS; PROSPECTIVE STUDIES; SUBCUTANEOUS FAT; TOMOGRAPHY, X-RAY COMPUTED; WEIGHT LOSS;

EID: 84951110611     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2015-2571     Document Type: Article

References (36)

1. Prentice AM. Overeating: The health risks. Obesity Res. 2001; 9(Suppl 4):234S-238S.
2. Dirinck E, Jorens PG, Covaci A, et al. Obesity and persistent organic pollutants: Possible obesogenic effect of organochlorine pesticides and polychlorinated biphenyls. Obesity (Silver Spring). 2011;19: 709-714.
3. Kelishadi R, Poursafa P, Jamshidi F. Role of environmental chemicals in obesity: A systematic review on the current evidence. J Environ Public Health. 2013;2013:896789.
4. Thayer KA, Heindel JJ, Bucher JR, Gallo MA. Role of environmental chemicals in diabetes and obesity: A National Toxicology Program workshop review. Environ Health Perspect. 2012;120:779-789.
5. Grün F, Blumberg B. Endocrine disrupters as obesogens. Mol Cell Endocrinol. 2009;304:19-29.
6. Aoki Y. Polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins, and polychlorinated dibenzofurans as endocrine disrupters- What we have learned from Yusho disease. Environ Res. 2001;86: 2-11.
7. Baillie-Hamilton PF. Chemical toxins: A hypothesis to explain the global obesity epidemic. J Altern Complement Med. 2002;8:185-192.
8. Vandenberg LN, Colborn T, Hayes TB, et al. Hormones and endocrine- disrupting chemicals: Low-dose effects and nonmonotonic dose responses. Endocr Rev. 2012;33:378-455.
9. Kong D, MacLeod M, Hung H, Cousins IT. Statistical analysis of long-term monitoring data for persistent organic pollutants in the atmosphere at 20 monitoring stations broadly indicates declining concentrations. Environ Sci Technol. 2014;48:12492-12499.
10. Elobeid MA, Padilla MA, Brock DW, Ruden DM, Allison DB. Endocrine disruptors and obesity: An examination of selected persistent organic pollutants in the NHANES 1999-2002 data. Int J Environ Res Public Health. 2010;7:2988-3005.
11. Tang-Pèronard JL, Andersen HR, Jensen TK, Heitmann BL. Endocrine- disrupting chemicals and obesity development in humans: A review. Obes Rev. 2011;12:622-636.
12. Van Gaal LF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature. 2006;444:875-880.
13. Wronska A, Kmiec Z. Structural and biochemical characteristics of various white adipose tissue depots. Acta Physiol (Oxf). 2012;205: 194-208.
14. Kuk JL, Katzmarzyk PT, NichamanMZ,Church TS, Blair SN, Ross R. Visceral fat is an independent predictor of all-cause mortality in men. Obesity (Silver Spring). 2006;14:336-341.
15. Lukaski HC, Bolonchuk WW. Estimation of body fluid volumes using tetrapolar bioelectrical impedance measurements. Aviat Space Environ Med. 1988;59:1163-1169.
16. Deurenberg P, Weststrate JA, Hautvast JG. Changes in fat-free mass during weight loss measured by bioelectrical impedance and by densitometry. Am J Clin Nutr. 1989;49:33-36.
17. van der Kooy K, Seidell JC. Techniques for the measurement of visceral fat: A practical guide. Int J Obes Relat Metab Disord. 1993; 17:187-196.
18. Phillips DL, Pirkle JL, Burse VW, Bernert JT Jr, Henderson LO, Needham LL. Chlorinated hydrocarbon levels in human serum: Effects of fasting and feeding. Arch Environ Contam Toxicol. 1989; 18:495-500.
19. Dirtu AC, Dirinck E, Malarvannan G, et al. Dynamics of organohalogenated contaminants in human serum from obese individuals during one year of weight loss treatment. Environ Sci Technol. 2013; 47(21):12441-12449.
20. Chevrier J, Dewailly E, Ayotte P, Mauriège P, Desprès JP, Tremblay A. Body weight loss increases plasma and adipose tissue concentrations of potentially toxic pollutants in obese individuals. Int J Obes Relat Metab Disord. 2000;24:1272-1278.
21. Imbeault P, Chevrier J, Dewailly E, et al. Increase in plasma pollutant levels in response to weight loss in humans is related to in vitro subcutaneous adipocyte basal lipolysis. Int J Obes Relat Metab Disord. 2001;25:1585-1591.
22. Pelletier C, Doucet E, Imbeault P, Tremblay A. Associations between weight loss-induced changes in plasma organochlorine concentrations, serum T(3) concentration, and resting metabolic rate. Toxicol Sci. 2002;67:46-51.
23. Mullerova D, Kopecky J, Matejkova D, et al. Negative association between plasma levels of adiponectin and polychlorinated biphenyl 153 in obese women under non-energy-restrictive regime. Int J Obes (Lond). 2008;32:1875-1878.
24. Charlier C, Desaive Cl, Plomteux G. Human exposure to endocrine disrupters: Consequences of gastroplasty on plasma concentration of toxic pollutants. Int J Obes Relat Metab Disord. 2002;26:1465-1468.
25. Hue O, Marcotte J, Berrigan F, et al. Increased plasma levels of toxic pollutants accompanying weight loss induced by hypocaloric diet or by bariatric surgery. Obes Surg. 2006;16:1145-1154.
26. Kim MJ, Marchand P, Henegar C, et al. Fate and complex pathogenic effects of dioxins and polychlorinated biphenyls in obese subjects before and after drastic weight loss. Environ Health Perspect. 2011;119:377-383.
27. Dirinck EL, Dirtu AC, Govindan M, Covaci A, Van Gaal LF, Jorens PG. Exposure to persistent organic pollutants: Relationship with abnormal glucose metabolism and visceral adiposity. Diabetes Care. 2014;37:1951-1958.
28. Louis C, Dirtu AC, Stas M, et al. Mobilisation of lipophilic pollutants from blubber in northern elephant seal pups (Mirounga angustirostris) during the post-weaning fast. Environ Res. 2014;132: 438-448.
29. De Roos AJ, Ulrich CM, Sjodin A, McTiernan A. Adiposity, body composition, and weight change in relation to organochlorine pollutant plasma concentrations. J Expo Sci Environ Epidemiol. 2012; 22:617-624.
30. Roos V, Ronn M, Salihovic S, et al. Circulating levels of persistent organic pollutants in relation to visceral and subcutaneous adipose tissue by abdominal MRI. Obesity (Silver Spring). 2013;21:413-418.
31. Li G, Zhang P, Wang J, et al. Cardiovascular mortality, all-cause mortality, and diabetes incidence after lifestyle intervention for people with impaired glucose tolerance in the Da Qing Diabetes Prevention Study: A 23-year follow-up study. Lancet Diabetes Endocrinol. 2014;2:474-480.
32. Van Gaal LF, Wauters MA, De Leeuw IH. The beneficial effects of modest weight loss on cardiovascular risk factors. Int J Obes Relat Metab Disord. 1997;21(Suppl 1):S5-S9.
33. Malarvannan G, Dirinck E, Dirtu AC, et al. Distribution of persistent organic pollutants in two different fat compartments from obese individuals. Environ Int. 2013;55:33-42.
34. Chaston TB, Dixon JB. Factors associated with percent change in visceral versus subcutaneous abdominal fat during weight loss: Findings from a systematic review. Int J Obes (Lond). 2008;32: 619-628.
35. Lavie CJ, De Schutter A, Milani RV. Healthy obese versus unhealthy lean: The obesity paradox. Nat Rev Endocrinol. 2015;11:55-62.
36. HongNS,KimKS, Lee IK, et al. The association between obesity and mortality in the elderly differs by serum concentrations of persistent organic pollutants: A possible explanation for the obesity paradox. Int J Obes (Lond). 2012;36:1170-1175.