Somatic variation of T-cell receptor genes strongly associate with HLA class restriction

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Klarenbeek, Paul L ^a,b,c   Doorenspleet, Marieke E ^c   Esveldt, Rebecca E E ^c   Van Schaik, Barbera D C ^c   Lardy, Neubury ^d   Van Kampen, Antoine H C ^c   Tak, Paul P ^c,f,g   Plenge, Robert M ^a,b,h   Baas, Frank ^c   De Bakker, Paul I W ^a,b,e   De Vries, Niek ^c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d Sanquin Diagnostiek   (Netherlands)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^f GLAXOSMITHKLINE   (United Kingdom)

^g UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^h MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CHAIN; AMINO ACID COMPOSITION; ARTICLE; BETA CHAIN; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; COMPLEMENTARITY DETERMINING REGION; GENE REARRANGEMENT; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; NORMAL HUMAN; T LYMPHOCYTE RECEPTOR GENE; T LYMPHOCYTE SUBPOPULATION; VDJ RECOMBINATION; CELL DIFFERENTIATION; CELL LINEAGE; GENETIC VARIATION; GENETICS; METABOLISM;

HLA ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR;

CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINEAGE; GENES, T-CELL RECEPTOR; GENES, T-CELL RECEPTOR ALPHA; GENES, T-CELL RECEPTOR BETA; GENETIC VARIATION; HLA ANTIGENS; HUMANS; RECEPTORS, ANTIGEN, T-CELL;

EID: 84950336015     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0140815     Document Type: Article

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