Evidence for a Prognostic Role of Orthostatic Hypertension on Survival in a Very Old Institutionalized Population

Hypertension

Volumn 67, Issue 1, 2016, Pages 191-196

  Agnoletti, Davide ^a,b   Valbusa, Filippo ^a   Labat, Carlos ^c,d   Gautier, Sylvie ^c   Mourad, Jean Jacques ^b   Benetos, Athanase ^c,d  

^a SACRO CUORE DON CALABRIA HOSPITAL   (Italy)

^b UNIVERSITÉ PARIS 13   (France)

^c UNIVERSITY HOSPITAL OF NANCY   (France)

^d INSERM UMR S 1116 University of Lorraine   (France)

Author keywords

cardiovascular; elderly; mortality; nursing homes; orthostatic hypertension; orthostatic hypotension

Indexed keywords

AGED; ARTICLE; AUGMENTATION INDEX; BLOOD PRESSURE MEASUREMENT; CARDIOVASCULAR MORTALITY; COHORT ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; FRAIL ELDERLY; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; MORBIDITY; MULTICENTER STUDY (TOPIC); OBESITY; ORTHOSTATIC HYPERTENSION; ORTHOSTATIC HYPOTENSION; PATIENT AUTONOMY; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PREVALENCE; PRIORITY JOURNAL; PROGNOSTIC ASSESSMENT; PULSE PRESSURE; PULSE WAVE; RISK ASSESSMENT; SCORING SYSTEM; SEX DIFFERENCE; SITTING; STANDING; SURVIVAL RATE; SYSTOLIC BLOOD PRESSURE; TONOMETRY; VERY ELDERLY; AGE; BLOOD PRESSURE; BODY POSTURE; CLINICAL TRIAL; EPIDEMIOLOGY; FRANCE; HYPERTENSION; INSTITUTIONALIZATION; MORTALITY; MULTICENTER STUDY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROGNOSIS; PROSPECTIVE STUDY; RISK FACTOR; TRENDS;

AGE FACTORS; AGED, 80 AND OVER; BLOOD PRESSURE; FEMALE; FOLLOW-UP STUDIES; FRANCE; HUMANS; HYPERTENSION; INSTITUTIONALIZATION; MALE; POSTURE; PROGNOSIS; PROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL RATE;

EID: 84950326946     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.115.06386     Document Type: Article

References (27)

1. Rose KM, Tyroler HA, Nardo CJ, Arnett DK, Light KC, Rosamond W, Sharrett AR, Szklo M. Orthostatic hypotension and the incidence of coronary heart disease: the Atherosclerosis Risk in Communities study. Am J Hypertens. 2000;13(6 Pt 1):571-578.
2. Masaki KH, Schatz IJ, Burchfiel CM, Sharp DS, Chiu D, Foley D, Curb JD. Orthostatic hypotension predicts mortality in elderly men: the Honolulu Heart Program. Circulation. 1998;98:2290-2295.
3. Ooi WL, Hossain M, Lipsitz LA. The association between orthostatic hypotension and recurrent falls in nursing home residents. Am J Med. 2000;108:106-111.
4. Fedorowski A, Stavenow L, Hedblad B, Berglund G, Nilsson PM, Melander O. Orthostatic hypotension predicts all-cause mortality and coronary events in middle-aged individuals (The Malmo Preventive Project). Eur Heart J. 2010;31:85-91. doi: 10.1093/eurheartj/ehp329.
5. Kario K, Eguchi K, Hoshide S, Hoshide Y, Umeda Y, Mitsuhashi T, Shimada K. U-curve relationship between orthostatic blood pressure change and silent cerebrovascular disease in elderly hypertensives: orthostatic hypertension as a new cardiovascular risk factor. J Am Coll Cardiol. 2002;40:133-141.
6. Fan XH, Wang Y, Sun K, Zhang W, Wang H, Wu H, Zhang H, Zhou X, Hui R. Disorders of orthostatic blood pressure response are associated with cardiovascular disease and target organ damage in hypertensive patients. Am J Hypertens. 2010;23:829-837. doi: 10.1038/ajh.2010.76.
7. Yatsuya H, Folsom AR, Alonso A, Gottesman RF, Rose KM; ARIC Study Investigators. Postural changes in blood pressure and incidence of ischemic stroke subtypes: the ARIC study. Hypertension. 2011;57:167-173. doi: 10.1161/HYPERTENSIONAHA.110.161844.
8. Benetos A, Buatois S, Salvi P, et al. Blood pressure and pulse wave velocity values in the institutionalized elderly aged 80 and over: baseline of the PARTAGE study. J Hypertens. 2010;28:41-50. doi: 10.1097/HJH.0b013e328332b879.
9. Charlson M, Szatrowski TP, Peterson J, Gold J. Validation of a combined comorbidity index. J Clin Epidemiol. 1994;47:1245-1251.
10. Katz S, Ford AB, Moskowitz RW, Jackson BA, Jaffe MW. Studies of illness in the aged. the index of ADL: a standardized measure of biological and psychosocial function. JAMA. 1963;185:914-919.
11. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12:189-198.
12. Valbusa F, Labat C, Salvi P, Vivian ME, Hanon O, Benetos A; PARTAGE investigators. Orthostatic hypotension in very old individuals living in nursing homes: the PARTAGE study. J Hypertens. 2012;30:53-60. doi: 10.1097/HJH.0b013e32834d3d73.
13. The Consensus Committee of the American Autonomic Society and the American Academy of Neurology. Consensus statement on the definition of orthostatic hypotension, pure autonomic failure, and multiple system atrophy. Neurology. 1996;46:1470.
14. Kario K. Orthostatic hypertension-a new haemodynamic cardiovascular risk factor. Nat Rev Nephrol. 2013;9:726-738. doi: 10.1038/nrneph.2013.224.
15. Fessel J, Robertson D. Orthostatic hypertension: when pressor reflexes overcompensate. Nat Clin Pract Nephrol. 2006;2:424-431. doi: 10.1038/ncpneph0228.
16. Zhang Y, Agnoletti D, Iaria P, Protogerou AD, Safar ME, Xu Y, Blacher J. Gender difference in cardiovascular risk factors in the elderly with cardiovascular disease in the last stage of lifespan: the PROTEGER study. Int J Cardiol. 2012;155:144-148. doi: 10.1016/j.ijcard.2011.09.073.
17. Wenner MM, Stachenfeld NS. Blood pressure and water regulation: understanding sex hormone effects within and between men and women. J Physiol. 2012;590(pt 23):5949-5961. doi: 10.1113/jphysiol.2012.236752.
18. Bouhanick B, Meliani S, Doucet J, Bauduceau B, Verny C, Chamontin B, Le Floch JP; Gerodiab Study Group. Orthostatic hypotension is associated with more severe hypertension in elderly autonomous diabetic patients from the French Gerodiab study at inclusion. Ann Cardiol Angeiol (Paris). 2014;63:176-182. doi: 10.1016/j.ancard.2014.05.013.
19. Eguchi K, Kario K, Hoshide S, Hoshide Y, Ishikawa J, Morinari M, Hashimoto T, Shimada K. Greater change of orthostatic blood pressure is related to silent cerebral infarct and cardiac overload in hypertensive subjects. Hypertens Res. 2004;27:235-241.
20. Hoshide S, Matsui Y, Shibasaki S, Eguchi K, Ishikawa J, Ishikawa S, Kabutoya T, Schwartz JE, Pickering TG, Shimada K, Kario K; Japan Morning Surge-1 Study Group. Orthostatic hypertension detected by self-measured home blood pressure monitoring: a new cardiovascular risk factor for elderly hypertensives. Hypertens Res. 2008;31:1509-1516. doi: 10.1291/hypres.31.1509.
21. Thomas RJ, Liu K, Jacobs DR, Jr, Bild DE, Kiefe CI, Hulley SB. Positional change in blood pressure and 8-year risk of hypertension: the CARDIA Study. Mayo Clin Proc. 2003;78:951-958. doi: 10.4065/78.8.951.
22. Veronese N, De Rui M, Bolzetta F, Zambon S, Corti MC, Baggio G, Toffanello ED, Maggi S, Crepaldi G, Perissinotto E, Manzato E, Sergi G. Orthostatic changes in blood pressure and mortality in the elderly: the pro.V.A study. Am J Hypertens. 2015;10:1-9.
23. Benetos A, Gautier S, Labat C, et al. Mortality and cardiovascular events are best predicted by low central/peripheral pulse pressure amplification but not by high blood pressure levels in elderly nursing home subjects: the PARTAGE (Predictive Values of Blood Pressure and Arterial Stiffness in Institutionalized Very Aged Population) study. J Am Coll Cardiol. 2012;60:1503-1511. doi: 10.1016/j.jacc.2012.04.055.
24. Benetos A, Labat C, Rossignol P, Fay R, Rolland Y, Valbusa F, Salvi P, Zamboni M, Manckoundia P, Hanon O, Gautier S. Treatment with multiple blood pressure medications, achieved blood pressure, and mortality in older nursing home residents: the PARTAGE study. JAMA Intern Med. 2015;175:989-995. doi: 10.1001/jamainternmed.2014.8012.
25. Smith JJ, Porth CM, Erickson M. Hemodynamic response to the upright posture. J Clin Pharmacol. 1994;34:375-386.
26. Barantke M, Krauss T, Ortak J, Lieb W, Reppel M, Burgdorf C, Pramstaller PP, Schunkert H, Bonnemeier H. Effects of gender and aging on differential autonomic responses to orthostatic maneuvers. J Cardiovasc Electrophysiol. 2008;19:1296-1303. doi: 10.1111/j.1540-8167.2008.01257.x.
27. Weiss A, Grossman E, Beloosesky Y, Grinblat J. Orthostatic hypotension in acute geriatric ward: is it a consistent finding? Arch Intern Med. 2002;162:2369-2374.