Orthostatic changes in blood pressure and mortality in the elderly: The Pro.V.A study

American Journal of Hypertension

Volumn 28, Issue 10, 2015, Pages 1248-1256

  Veronese, Nicola ^a   De Rui, Marina ^a   Bolzetta, Francesco ^a   Zambon, Sabina ^a,b   Corti, Maria Chiara ^c   Baggio, Giovanella ^d   Toffanello, Elena Debora ^a   Maggi, Stefania ^b   Crepaldi, Gaetano ^b   Perissinotto, Egle ^a   Manzato, Enzo ^a,b   Sergi, Giuseppe ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b CNR   (Italy)

^c Division of Health Care Planning and Evaluation of the Regione Veneto   (Italy)

^d UNIVERSITY HOSPITAL OF PADOVA   (Italy)

Author keywords

blood pressure; cardiovascular disease; elderly; hypertension; mortality; orthostatic hypertension; orthostatic hypotension

Indexed keywords

ACETYLSALICYLIC ACID; ANTIHYPERTENSIVE AGENT; ANTIPARKINSON AGENT; BENZODIAZEPINE DERIVATIVE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NITRIC ACID DERIVATIVE; VASODILATOR AGENT;

AGED; AGING; ANTIHYPERTENSIVE THERAPY; ARTICLE; ATRIAL FIBRILLATION; BLOOD PRESSURE; BLOOD PRESSURE MEASUREMENT; BODY MASS; BODY WEIGHT; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; COMMUNITY; CONFIDENCE INTERVAL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; DIURETIC THERAPY; FEMALE; FOLLOW UP; HAZARD RATIO; HEART FAILURE; HUMAN; MAJOR CLINICAL STUDY; MALE; ORTHOSTATIC HYPERTENSION; ORTHOSTATIC HYPOTENSION; PARKINSON DISEASE; PREDICTOR VARIABLE; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; RISK FACTOR; STANDING; SYSTOLIC BLOOD PRESSURE; COHORT ANALYSIS; EPIDEMIOLOGY; HYPERTENSION; ITALY; MORTALITY; VERY ELDERLY;

AGED; AGED, 80 AND OVER; BLOOD PRESSURE; COHORT STUDIES; FEMALE; HUMANS; HYPERTENSION; HYPOTENSION, ORTHOSTATIC; ITALY; MALE;

EID: 84931289211     PISSN: 08957061     EISSN: 19417225     Source Type: Journal    
DOI: 10.1093/ajh/hpv022     Document Type: Article

References (29)

1. Gupta V, Lipsitz LA. Orthostatic hypotension in the elderly: diagnosis and treatment. Am J Med 2007; 120:841-847.
2. Veronese N, Bolzetta F, De Rui M, Zambon S, Corti MC, Musacchio E, Baggio G, Crepaldi G, Perissinotto E, Manzato E, Sergi G. Serum 25-hydroxyvitamin D and orthostatic hypotension in old people: the Pro.V.A. study. Hypertension 2014; 64:481-486.
3. Xin W, Lin Z, Mi S. Orthostatic hypotension and mortality risk: a metaanalysis of cohort studies. Heart 2014; 100:406-413.
4. Rose KM, Tyroler HA, Nardo CJ, Arnett DK, Light KC, Rosamond W, Sharrett AR, Szklo M. Orthostatic hypotension and the incidence of coronary heart disease: the Atherosclerosis Risk in Communities study. Am J Hypertens 2000; 13:571-578.
5. Eigenbrodt ML, Rose KM, Couper DJ, Arnett DK, Smith R, Jones D. Orthostatic hypotension as a risk factor for stroke: the atherosclerosis risk in communities (ARIC) study, 1987-1996. Stroke 2000; 31:2307-2313.
6. Jones CD, Loehr L, Franceschini N, Rosamond WD, Chang PP, Shahar E, Couper DJ, Rose KM. Orthostatic hypotension as a risk factor for incident heart failure: the atherosclerosis risk in communities study. Hypertension 2012; 59:913-918.
7. Casiglia E, Tikhonoff V, Caffi S, Boschetti G, Giordano N, Guidotti F, Segato F, Mazza A, Grasselli C, Saugo M, Rigoni G, Guglielmi F, Martini B, Palatini P. Orthostatic hypotension does not increase cardiovascular risk in the elderly at a population level. Am J Hypertens 2014; 27:81-88.
8. Fedorowski A, Engström G, Hedblad B, Melander O. Orthostatic hypotension predicts incidence of heart failure: the Malmö preventive project. Am J Hypertens 2010; 23:1209-1215.
9. Sung SH, Chen ZY, Tseng TW, Lu DY, Yu WC, Cheng HM, Chen CH. Wave reflections, arterial stiffness, and orthostatic hypotension. Am J Hypertens 2014; 27:1446-1455.
10. Robertson D. Orthostatic hypertension: the last hemodynamic frontier. Hypertension 2011; 57:158-159.
11. Kario K. Orthostatic hypertension-A new haemodynamic cardiovascular risk factor. Nat Rev Nephrol 2013; 9:726-738.
12. Eguchi K, Kario K, Hoshide S, Hoshide Y, Ishikawa J, Morinari M, Hashimoto T, Shimada K. Greater change of orthostatic blood pressure is related to silent cerebral infarct and cardiac overload in hypertensive subjects. Hypertens Res 2004; 27:235-241.
13. Corti MC, Guralnik JM, Sartori L, Baggio G, Manzato E, Pezzotti P, Barbato G, Zambon S, Ferrucci L, Minervini S, Musacchio E, Crepaldi G. The effect of cardiovascular and osteoarticular diseases on disability in older Italian men and women: rationale, design, and sample characteristics of the Progetto Veneto Anziani (PRO.V.A.) study. J Am Geriatr Soc 2002; 50:1535-1540.
14. Folstein MF, Robins LN, Helzer JE. The mini-mental state examination. Arch Gen Psychiatry 1983; 40:812.
15. Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, Leirer VO. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 1982; 17:37-49.
16. Katz S, Downs TD, Cash HR, Grotz RC. Progress in development of the index of ADL. Gerontologist 1970; 10:20-30.
17. Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, Scherr PA, Wallace RB. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 1994; 49:M85-M94.
18. Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves J, Hill MN, Jones DW, Kurtz T, Sheps SG, Roccella EJ; Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Recommendations for blood pressure measurement in humans and experimental animals: Part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Hypertension 2005; 45:142-161.
19. The Consensus Committee of the American Autonomic Society and the American Academy of Neurology. Consensus statement on the definition of orthostatic hypotension, pure autonomic failure, and multiple system atrophy. Neurology 1996; 46:1470.
20. Yatsuya H, Folsom AR, Alonso A, Gottesman RF, Rose KM; ARIC Study Investigators. Postural changes in blood pressure and incidence of ischemic stroke subtypes: the ARIC study. Hypertension 2011; 57:167-173.
21. Fan XH, Wang Y, Sun K, Zhang W, Wang H, Wu H, Zhang H, Zhou X, Hui R. Disorders of orthostatic blood pressure response are associated with cardiovascular disease and target organ damage in hypertensive patients. Am J Hypertens 2010; 23:829-837.
22. Kario K. Orthostatic hypertension: a measure of blood pressure variation for predicting cardiovascular risk. Circ J 2009; 73:1002-1007.
23. Ketch T, Biaggioni I, Robertson R, Robertson D. Four faces of baroreflex failure: hypertensive crisis, volatile hypertension, orthostatic tachycardia, and malignant vagotonia. Circulation 2002; 105:2518-2523.
24. Barochiner J, Cuffaro PE, Aparicio LS, Alfie J, Rada MA, Morales MS, Galarza CR, Waisman GD. Predictors of masked hypertension among treated hypertensive patients: an interesting association with orthostatic hypertension. Am J Hypertens 2013; 26:872-878.
25. Verwoert GC, Mattace-Raso FU, Hofman A, Heeringa J, Stricker BH, Breteler MM, Witteman JC. Orthostatic hypotension and risk of cardiovascular disease in elderly people: the Rotterdam study. J Am Geriatr Soc 2008; 56:1816-1820.
26. Benvenuto LJ, Krakoff LR. Morbidity and mortality of orthostatic hypotension: implications for management of cardiovascular disease. Am J Hypertens 2011; 24:135-144.
27. Masaki KH, Schatz IJ, Burchfiel CM, Sharp DS, Chiu D, Foley D, Curb JD. Orthostatic hypotension predicts mortality in elderly men: the Honolulu Heart Program. Circulation 1998; 98:2290-2295.
28. Weiss A, Grossman E, Beloosesky Y, Grinblat J. Orthostatic hypotension in acute geriatric ward: is it a consistent finding?. Arch Intern Med 2002; 162:2369-2374.
29. Low PA, Singer W. Management of neurogenic orthostatic hypotension: an update. Lancet Neurol 2008; 7:451-458.