Glycoproteomic studies of IgE from a novel hyper IgE syndrome linked to PGM3 mutation

Glycoconjugate Journal

Volumn 33, Issue 3, 2016, Pages 447-456

  Wu, Gang ^a,b   Hitchen, Paul G ^a   Panico, Maria ^a   North, Simon J ^a   Barbouche, Mohamed Ridha ^c   Binet, Daniel ^d   Morris, Howard R ^a,d   Dell, Anne ^a   Haslam, Stuart M ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c UNIVERSITY OF TUNIS EL MANAR   (Tunisia)

^d MS RTC (Mass Spectrometry Research and Training Centre)   (United Kingdom)

Author keywords

Glycoproteomics; Hyper IgE Syndrome; IgE; Phosphoglucomutase 3

Indexed keywords

GLYCAN; IMMUNOGLOBULIN E; MANNOSE; PHOSPHOGLUCOMUTASE; GLYCOPROTEIN; PGM3 PROTEIN, HUMAN; PROTEOME;

AMINO ACID SEQUENCE; ARTICLE; ATOPIC DERMATITIS; CARBOHYDRATE ANALYSIS; CASE REPORT; CONTROLLED STUDY; GENE; GENE MUTATION; GLYCOPROTEOMIC STUDY; HUMAN; HYPER IGE SYNDROME; IMMUNOPRECIPITATION; MOLECULAR WEIGHT; PGM3 GENE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEOMICS; BINDING SITE; CHEMISTRY; GENETICS; GLYCOSYLATION; MASS SPECTROMETRY; METABOLISM; MOLECULAR DIAGNOSIS; MUTATION; PROCEDURES; PROTEIN PROCESSING;

BINDING SITES; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; IMMUNOGLOBULIN E; JOB SYNDROME; MASS SPECTROMETRY; MOLECULAR DIAGNOSTIC TECHNIQUES; MUTATION; PHOSPHOGLUCOMUTASE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOME;

EID: 84950253163     PISSN: 02820080     EISSN: 15734986     Source Type: Journal    
DOI: 10.1007/s10719-015-9638-y     Document Type: Article

References (26)

1. Arnold, J.N., Wormald, M.R., Sim, R.B., Rudd, P.M., Dwek, R.A.: The impact of glycosylation on the biological function and structure of human immunoglobulins. Annu. Rev. Immunol. 25, 21–50 (2007)
2. Parekh, R.B., Dwek, R.A., Sutton, B.J., Fernandes, D.L., Leung, A., Stanworth, D., Rademacher, T.W., Mizuochi, T., Taniguchi, T., Matsuta, K., et al.: Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG. Nature 316(6027), 452–457 (1985)
3. Anthony, R.M., Wermeling, F., Ravetch, J.V.: Novel roles for the IgG Fc glycan. Ann. N. Y. Acad. Sci. 1253, 170–180 (2012)
4. Scallon, B.J., Tam, S.H., McCarthy, S.G., Cal, A.N., Raju, T.S.: Higher levels of sialylated Fc glycans in immunoglobulin G molecules can adversely impact functionality. Mol. Immunol. 44(7), 1524–1534 (2007)
5. Anthony, R.M., Wermeling, F., Karlsson, M.C., Ravetch, J.V.: Identification of a receptor required for the anti-inflammatory activity of IVIG. Proc. Natl. Acad. Sci. U. S. A. 105(50), 19571–19578 (2008)
6. Royle, L., Roos, A., Harvey, D.J., Wormald, M.R., van Gijlswijk-Janssen, D., Redwan, E.M., Wilson, I.A., Daha, M.R., Dwek, R.A., Rudd, P.M.: Secretory IgA N- and O-glycans provide a link between the innate and adaptive immune systems. J. Biol. Chem. 278(22), 20140–20153 (2003)
7. Basset, C., Devauchelle, V., Durand, V., Jamin, C., Pennec, Y.L., Youinou, P., Dueymes, M.: Glycosylation of immunoglobulin A influences its receptor binding. Scand. J. Immunol. 50(6), 572–579 (1999)
8. Goetze, A.M., Liu, Y.D., Zhang, Z., Shah, B., Lee, E., Bondarenko, P.V., Flynn, G.C.: High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans. Glycobiology 21(7), 949–959 (2011)
9. Gould, H.J., Sutton, B.J.: IgE in allergy and asthma today. Nat. Rev. Immunol. 8(3), 205–217 (2008)
10. Dorrington, K.J., Bennich, H.H.: Structure-function relationships in human immunoglobulin E. Immunol. Rev. 41, 3–25 (1978)
11. Baenziger, J., Kornfeld, S., Kochwa, S.: Structure of the carbohydrate units of IgE immunoglobulin. II. Sequence of the sialic acid-containing glycopeptides. J. Biol. Chem. 249(6), 1897–1903 (1974)
12. Baenziger, J., Kornfeld, S., Kochwa, S.: Structure of the carbohydrate units of IgE immunoglobulin. I. Over-all composition, glycopeptide isolation, and structure of the high mannose oligosaccharide unit. J. Biol. Chem. 249(6), 1889–1896 (1974)
13. Arnold, J.N., Radcliffe, C.M., Wormald, M.R., Royle, L., Harvey, D.J., Crispin, M., Dwek, R.A., Sim, R.B., Rudd, P.M.: The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan-binding lectin. J. Immunol. 173(11), 6831–6840 (2004)
14. Plomp, R., Hensbergen, P.J., Rombouts, Y., Zauner, G., Dragan, I., Koeleman, C.A., Deelder, A.M., Wuhrer, M.: Site-specific N-glycosylation analysis of human immunoglobulin e. J. Proteome Res. 13(2), 536–546 (2014)
15. Yong, P.F.K., Freeman, A.F., Engelhardt, K.R., Holland, S., Puck, J.M., Grimbacher, B.: An update on the hyper-IgE syndromes. Arthritis Res. Ther. 14(6), 228 (2012)
16. Davis, S.D., Schaller, J., Wedgwood, R.J.: Job’s Syndrome. Recurrent, “cold”, staphylococcal abscesses. Lancet 1, 1013–1015 (1966)
17. Grimbacher, B., Holland, S.M., Gallin, J.I., Greenberg, F., Hill, S.C., Malech, H.L., Miller, J.A., O’Connell, A.C., Puck, J.M.: Hyper-IgE syndrome with recurrent infections—an autosomal dominant multisystem disorder. N. Engl. J. Med. 340(9), 692–702 (1999)
18. Holland, S.M., DeLeo, F.R., Elloumi, H.Z., Hsu, A.P., Uzel, G., Brodsky, N., Freeman, A.F., Demidowich, A., Davis, J., Turner, M.L., Anderson, V.L., Darnell, D.N., Welch, P.A., Kuhns, D.B., Frucht, D.M., Malech, H.L., Gallin, J.I., Kobayashi, S.D., Whitney, A.R., Voyich, J.M., Musser, J.M., Woellner, C., Schaffer, A.A., Puck, J.M., Grimbacher, B.: STAT3 mutations in the hyper-IgE syndrome. N. Engl. J. Med. 357(16), 1608–1619 (2007)
19. Minegishi, Y., Saito, M., Tsuchiya, S., Tsuge, I., Takada, H., Hara, T., Kawamura, N., Ariga, T., Pasic, S., Stojkovic, O., Metin, A., Karasuyama, H.: Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome. Nature 448(7157), 1058–1062 (2007)
20. Zhang, Q.A., Davis, J.C., Dove, C.G., Su, H.C.: Genetic, clinical, and laboratory markers for DOCK8 immunodeficiency syndrome. Dis. Markers 29(3–4), 131–139 (2010)
21. Engelhardt, K.R., McGhee, S., Winkler, S., Sassi, A., Woellner, C., Lopez-Herrera, G., Chen, A., Kim, H.S., Lloret, M.G., Schulze, I., Ehl, S., Thiel, J., Pfeifer, D., Veelken, H., Niehues, T., Siepermann, K., Weinspach, S., Reisli, I., Keles, S., Genel, F., Kutuculer, N., Camcioglu, Y., Somer, A., Karakoc-Aydiner, E., Barlan, I., Gennery, A., Metin, A., Degerliyurt, A., Pietrogrande, M.C., Yeganeh, M., Baz, Z., Al-Tamemi, S., Klein, C., Puck, J.M., Holland, S.M., McCabe, E.R.B., Grimbacher, B., Chatila, T.A.: Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome. J. Allergy Clin. Immunol. 124(6), 1289–1302 (2009)
22. Zhang, Y., Yu, X., Ichikawa, M., Lyons, J.J., Datta, S., Lamborn, I.T., Jing, H., Kim, E.S., Biancalana, M., Wolfe, L.A., DiMaggio, T., Matthews, H.F., Kranick, S.M., Stone, K.D., Holland, S.M., Reich, D.S., Hughes, J.D., Mehmet, H., McElwee, J., Freeman, A.F., Freeze, H.H., Su, H.C., Milner, J.D.: Autosomal recessive phosphoglucomutase 3 (PGM3) mutations link glycosylation defects to atopy, immune deficiency, autoimmunity, and neurocognitive impairment. J. Allergy Clin. Immunol. 133(5), 1400–1409 (2014). 1409 e1401–1405
23. Sassi, A., Lazaroski, S., Wu, G., Haslam, S.M., Fliegauf, M., Mellouli, F., Patiroglu, T., Unal, E., Ozdemir, M.A., Jouhadi, Z., Khadir, K., Ben-Khemis, L., Ben-Ali, M., Ben-Mustapha, I., Borchani, L., Pfeifer, D., Jakob, T., Khemiri, M., Asplund, A.C., Gustafsson, M.O., Lundin, K.E., Falk-Sorqvist, E., Moens, L.N., Gungor, H.E., Engelhardt, K.R., Dziadzio, M., Stauss, H., Fleckenstein, B., Meier, R., Prayitno, K., Maul-Pavicic, A., Schaffer, S., Rakhmanov, M., Henneke, P., Kraus, H., Eibel, H., Kolsch, U., Nadifi, S., Nilsson, M., Bejaoui, M., Schaffer, A.A., Smith, C.I., Dell, A., Barbouche, M.R., Grimbacher, B.: Hypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levels. J. Allergy Clin. Immunol. 133(5), 1410–1419 (2014). 1419 e1411–1413
24. Harrison, R., Hitchen, P.G., Panico, M., Morris, H.R., Mekhaiel, D., Pleass, R.J., Dell, A., Hewitt, J.E., Haslam, S.M.: Glycoproteomic characterization of recombinant mouse alpha-dystroglycan. Glycobiology 22(5), 662–675 (2012)
25. Hart, G.W., Slawson, C., Ramirez-Correa, G., Lagerlof, O.: Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease. Annu. Rev. Biochem. 80(80), 825–858 (2011)
26. Greig, K.T., Antonchuk, J., Metcalf, D., Morgan, P.O., Krebs, D.L., Zhang, J.G., Hacking, D.F., Bode, L., Robb, L., Kranz, C., de Graaf, C., Bahlo, M., Nicola, N.A., Nutt, S.L., Freeze, H.H., Alexander, W.S., Hilton, D.J., Kile, B.T.: Agm1/Pgm-3-mediated sugar nucleotide synthesis is essential for hematopoiesis and development. Mol. Cell. Biol. 27(16), 5849–5859 (2007)