-
1
-
-
60749123372
-
Modelling the human immune response: Performance of a 10e11 human antibody repertoire against a broad panel of therapeutically relevant antigens
-
Lloyd C, Lowe D, Edwards B et al (2009) Modelling the human immune response: performance of a 10e11 human antibody repertoire against a broad panel of therapeutically relevant antigens. Protein Eng Des Sel 22 (3):159-168
-
(2009)
Protein Eng Des Sel
, vol.22
, Issue.3
, pp. 159-168
-
-
Lloyd, C.1
Lowe, D.2
Edwards, B.3
-
2
-
-
77957361348
-
Development trends for human monoclonal antibody therapeutics
-
Nelson AL, Dhimolea E, Reichert JM (2010) Development trends for human monoclonal antibody therapeutics. Nat Rev Drug Discov 9(10):767-774
-
(2010)
Nat Rev Drug Discov
, vol.9
, Issue.10
, pp. 767-774
-
-
Nelson, A.L.1
Dhimolea, E.2
Reichert, J.M.3
-
3
-
-
0142257954
-
The remarkable flexibility of the human antibody repertoire; isolation of over one thousand different antibodies to a single protein, BLyS
-
Edwards BM, Barash SC, Main SH et al (2003) The remarkable flexibility of the human antibody repertoire; isolation of over one thousand different antibodies to a single protein, BLyS. J MolBiol 334(1):103-118
-
(2003)
J Molbiol
, vol.334
, Issue.1
, pp. 103-118
-
-
Edwards, B.M.1
Barash, S.C.2
Main, S.H.3
-
4
-
-
38849154606
-
Application of phage display to high throughput antibody generation and characterization
-
Schofield DJ, Pope AR, Clementel V et al (2007) Application of phage display to high throughput antibody generation and characterization. Genome Biol 8(11):R254
-
(2007)
Genome Biol
, vol.8
, Issue.11
, pp. R254
-
-
Schofield, D.J.1
Pope, A.R.2
Clementel, V.3
-
5
-
-
39349106325
-
Differentiation of embryonic stem cells to clinically relevant populations: Lessons from embryonic development
-
Murry CE, Keller G (2008) Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell 132(4):661-680
-
(2008)
Cell
, vol.132
, Issue.4
, pp. 661-680
-
-
Murry, C.E.1
Keller, G.2
-
6
-
-
84887037302
-
Selecting antagonistic antibodies that control differentiation through inducible expression in embryonic stem cells
-
Melidoni AN, Dyson MR, Wormald S, McCafferty J (2013) Selecting antagonistic antibodies that control differentiation through inducible expression in embryonic stem cells. Proc Natl Acad Sci U S A 110(44):17802-17807
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.44
, pp. 17802-17807
-
-
Melidoni, A.N.1
Dyson, M.R.2
Wormald, S.3
McCafferty, J.4
-
7
-
-
0035029433
-
A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent
-
Vooijs M, Jonkers J, Berns A (2001) A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent. EMBO Rep 2(4):292-297
-
(2001)
EMBO Rep
, vol.2
, Issue.4
, pp. 292-297
-
-
Vooijs, M.1
Jonkers, J.2
Berns, A.3
-
8
-
-
0034633526
-
Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells
-
Schuldiner M, Yanuka O, Itskovitz-Eldor J et al (2000) Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A 97(21):11307-11312
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.21
, pp. 11307-11312
-
-
Schuldiner, M.1
Yanuka, O.2
Itskovitz-Eldor, J.3
-
9
-
-
80755187146
-
Acti-vin, BMP and FGF pathways cooperate to promote endoderm and pancreatic lineage cell differentiation from human embryonic stem cells
-
Xu X, Browning VL, Odorico JS (2010) Acti-vin, BMP and FGF pathways cooperate to promote endoderm and pancreatic lineage cell differentiation from human embryonic stem cells. Mech Dev 128(7-10):412-427
-
(2010)
Mech Dev
, vol.128
, Issue.7-1
, pp. 412-427
-
-
Xu, X.1
Browning, V.L.2
Odorico, J.S.3
-
10
-
-
79952399087
-
Recombinant antibodies and in vitro selection technologies
-
Bradbury AR, Sidhu S, Dubel S, McCafferty J (2011) Recombinant antibodies and in vitro selection technologies. Nat Biotechnol 29 (3):245-254
-
(2011)
Nat Biotechnol
, vol.29
, Issue.3
, pp. 245-254
-
-
Bradbury, A.R.1
Sidhu, S.2
Dubel, S.3
McCafferty, J.4
-
11
-
-
77956412152
-
Tracing the derivation of embryonic stem cells from the inner cell mass by single-cell RNA seqanalysis
-
Tang F, Barbacioru C, Bao S et al (2010) Tracing the derivation of embryonic stem cells from the inner cell mass by single-cell RNA seqanalysis. Cell Stem Cell 6(5):468-478
-
(2010)
Cell Stem Cell
, vol.6
, Issue.5
, pp. 468-478
-
-
Tang, F.1
Barbacioru, C.2
Bao, S.3
-
12
-
-
37549002155
-
Nanog safeguards pluripotency and mediates germline development
-
Chambers I, Silva J, Colby D et al (2007) Nanog safeguards pluripotency and mediates germline development. Nature 450 (7173):1230-1234
-
(2007)
Nature
, vol.450
, Issue.7173
, pp. 1230-1234
-
-
Chambers, I.1
Silva, J.2
Colby, D.3
-
13
-
-
79959950773
-
Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotencynetwork and increases embryonic stem cell resistance to differentiation
-
Wray J, Kalkan T, Gomez-Lopez S et al (2011) Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotencynetwork and increases embryonic stem cell resistance to differentiation. Nat Cell Biol 13 (7):838-845
-
(2011)
Nat Cell Biol
, vol.13
, Issue.7
, pp. 838-845
-
-
Wray, J.1
Kalkan, T.2
Gomez-Lopez, S.3
-
14
-
-
0034898556
-
Identification of receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis
-
Bellosta P, Iwahori A, Plotnikov AN et al (2001) Identification of receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis. Mol Cell Biol 21 (17):5946-5957
-
(2001)
Mol Cell Biol
, vol.21
, Issue.17
, pp. 5946-5957
-
-
Bellosta, P.1
Iwahori, A.2
Plotnikov, A.N.3
-
15
-
-
34548587064
-
FGF stimulation of the Erk1/ 2 signalling cascade triggers transition of plu-ripotent embryonic stem cells from self-renewal to lineage commitment
-
Kunath T, Saba-El-Leil MK, Almousailleakh M et al (2007) FGF stimulation of the Erk1/ 2 signalling cascade triggers transition of plu-ripotent embryonic stem cells from self-renewal to lineage commitment. Development 134(16):2895-2902
-
(2007)
Development
, vol.134
, Issue.16
, pp. 2895-2902
-
-
Kunath, T.1
Saba-El-Leil, M.K.2
Almousailleakh, M.3
-
16
-
-
34548596749
-
Adiscrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification
-
Stavridis MP, Simon Lunn J et al (2007) Adiscrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification. Development 134(16):2889-2894
-
(2007)
Development
, vol.134
, Issue.16
, pp. 2889-2894
-
-
Stavridis, M.P.1
Simon Lunn, J.2
-
17
-
-
44349170450
-
The ground state of embryonic stem cell self-renewal
-
Ying QL, Wray J, Nichols J et al (2008) The ground state of embryonic stem cell self-renewal. Nature 453(7194):519-523
-
(2008)
Nature
, vol.453
, Issue.7194
, pp. 519-523
-
-
Ying, Q.L.1
Wray, J.2
Nichols, J.3
-
18
-
-
84868377211
-
Generation of anti-Notch antibodies and their application in blocking Notch signalling in neural stem cells
-
Falk R, Falk A, Dyson MR et al (2012) Generation of anti-Notch antibodies and their application in blocking Notch signalling in neural stem cells. Methods 58(1):69-78
-
(2012)
Methods
, vol.58
, Issue.1
, pp. 69-78
-
-
Falk, R.1
Falk, A.2
Dyson, M.R.3
-
19
-
-
0033676098
-
DNA cloning using in vitro site-specific recombination
-
Hartley JL, Temple GF, Brasch MA (2000) DNA cloning using in vitro site-specific recombination. Genome Res 10(11):1788-1795
-
(2000)
Genome Res
, vol.10
, Issue.11
, pp. 1788-1795
-
-
Hartley, J.L.1
Temple, G.F.2
Brasch, M.A.3
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