Citrem modulates internal nanostructure of glyceryl monooleate dispersions and bypasses complement activation: Towards development of safe tunable intravenous lipid nanocarriers

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 11, Issue 8, 2015, Pages 1909-1914

  Wibroe, Peter P ^a   Mat Azmi, Intan D ^a   Nilsson, Christa ^a   Yaghmur, Anan ^a   Moghimi, S Moein ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Citrem; Complement system; Hexosomes; Hierarchical materials; Synchrotron small angle X ray scattering (SAXS)

Indexed keywords

BLOOD; DISPERSIONS; NANOSTRUCTURES; NANOSYSTEMS; X RAY SCATTERING;

CITREM; COMPLEMENT SYSTEMS; HEXOSOMES; HIERARCHICAL MATERIALS; SYNCHROTRON SMALL-ANGLE X-RAY SCATTERINGS;

CHEMICAL ACTIVATION;

CITREM; CITRIC ACID; GLYCEROL OLEATE; LIPID NANOCARRIER; MEDIUM CHAIN TRIACYLGLYCEROL; NANOCARRIER; POLOXAMER; STABILIZING AGENT; UNCLASSIFIED DRUG; ACYLGLYCEROL; DRUG CARRIER; EXCIPIENT; NANOMATERIAL; TRIACYLGLYCEROL;

ARTICLE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; DISPERSION; ERYTHROCYTE; HEMOLYSIS; HUMAN; HUMAN CELL; LIQUID CRYSTAL; LYOTROPIC NON LAMELLAR LIQUID CRYSTALLINE AQUEOUS NANODISPERSION; MICELLE; MOLECULAR STABILITY; NANOENGINEERING; SAFETY; TRANSMISSION ELECTRON MICROSCOPY; X RAY CRYSTALLOGRAPHY; ADVERSE EFFECTS; ANALOGS AND DERIVATIVES; CHEMISTRY; DRUG EFFECTS; ESTERIFICATION; SMALL ANGLE SCATTERING; X RAY DIFFRACTION;

CITRIC ACID; COMPLEMENT ACTIVATION; DRUG CARRIERS; ESTERIFICATION; EXCIPIENTS; GLYCERIDES; HUMANS; LIQUID CRYSTALS; NANOSTRUCTURES; SCATTERING, SMALL ANGLE; TRIGLYCERIDES; X-RAY DIFFRACTION;

EID: 84949960716     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2015.08.003     Document Type: Article

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