-
1
-
-
65649115060
-
Hypoxia helps glioma to fight therapy
-
Amberger-Murphy V. Hypoxia helps glioma to fight therapy. Curr. Cancer Drug Targets 2009, 9(3):381-390.
-
(2009)
Curr. Cancer Drug Targets
, vol.9
, Issue.3
, pp. 381-390
-
-
Amberger-Murphy, V.1
-
2
-
-
79957873952
-
Stromal-derived factor 1 alpha secreted by human CD133-derived multipotent stromal cells promotes neural progenitor cell survival through CXCR7
-
Bakondi B., Shimada I.S., Peterson B.M., Spees J.L. Stromal-derived factor 1 alpha secreted by human CD133-derived multipotent stromal cells promotes neural progenitor cell survival through CXCR7. Stem Cells Dev. 2011, 20(6):1021-1029.
-
(2011)
Stem Cells Dev.
, vol.20
, Issue.6
, pp. 1021-1029
-
-
Bakondi, B.1
Shimada, I.S.2
Peterson, B.M.3
Spees, J.L.4
-
3
-
-
33846149645
-
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
-
Batchelor T.T., Sorensen A.G., di Tomaso E., Zhang W.T., Duda D.G., Cohen K.S., Kozak K.R., Cahill D.P., Chen P.J., Zhu M., Ancukiewicz M., Mrugala M.M., Plotkin S., Drappatz J., Louis D.N., Ivy P., Scadden D.T., Benner T., Loeffler J.S., Wen P.Y., Jain R.K. AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell 2007, 11(1):83-95.
-
(2007)
Cancer Cell
, vol.11
, Issue.1
, pp. 83-95
-
-
Batchelor, T.T.1
Sorensen, A.G.2
di Tomaso, E.3
Zhang, W.T.4
Duda, D.G.5
Cohen, K.S.6
Kozak, K.R.7
Cahill, D.P.8
Chen, P.J.9
Zhu, M.10
Ancukiewicz, M.11
Mrugala, M.M.12
Plotkin, S.13
Drappatz, J.14
Louis, D.N.15
Ivy, P.16
Scadden, D.T.17
Benner, T.18
Loeffler, J.S.19
Wen, P.Y.20
Jain, R.K.21
more..
-
4
-
-
77951754737
-
Lipid metabolism impairment in human gliomas: expression of peroxisomal proteins in human gliomas at different grades of malignancy
-
Benedetti E., Galzio R., Laurenti G., D'Angelo B., Melchiorre E., Cifone M.G., Fanelli F., Muzi P., Coletti G., Alecci M., Sotgiu A., Ceru M.P., Cimini A. Lipid metabolism impairment in human gliomas: expression of peroxisomal proteins in human gliomas at different grades of malignancy. Int. J. Immunopathol. Pharmacol. 2010, 23(1):235-246.
-
(2010)
Int. J. Immunopathol. Pharmacol.
, vol.23
, Issue.1
, pp. 235-246
-
-
Benedetti, E.1
Galzio, R.2
Laurenti, G.3
D'Angelo, B.4
Melchiorre, E.5
Cifone, M.G.6
Fanelli, F.7
Muzi, P.8
Coletti, G.9
Alecci, M.10
Sotgiu, A.11
Ceru, M.P.12
Cimini, A.13
-
5
-
-
84862777272
-
Contribution of CXCL12 secretion to invasion of breast cancer cells
-
Boimel P.J., Smirnova T., Zhou Z.N., Wyckoff J., Park H., Coniglio S.J., Qian B.Z., Stanley E.R., Cox D., Pollard J.W., Muller W.J., Condeelis J., Segall J.E. Contribution of CXCL12 secretion to invasion of breast cancer cells. Breast Cancer Res. 2012, 14(1):R23.
-
(2012)
Breast Cancer Res.
, vol.14
, Issue.1
, pp. R23
-
-
Boimel, P.J.1
Smirnova, T.2
Zhou, Z.N.3
Wyckoff, J.4
Park, H.5
Coniglio, S.J.6
Qian, B.Z.7
Stanley, E.R.8
Cox, D.9
Pollard, J.W.10
Muller, W.J.11
Condeelis, J.12
Segall, J.E.13
-
6
-
-
0842325802
-
Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population
-
Brat D.J., Castellano-Sanchez A.A., Hunter S.B., Pecot M., Cohen C., Hammond E.H., Devi S.N., Kaur B., Van Meir E.G. Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population. Cancer Res. 2004, 64(3):920-927.
-
(2004)
Cancer Res.
, vol.64
, Issue.3
, pp. 920-927
-
-
Brat, D.J.1
Castellano-Sanchez, A.A.2
Hunter, S.B.3
Pecot, M.4
Cohen, C.5
Hammond, E.H.6
Devi, S.N.7
Kaur, B.8
Van Meir, E.G.9
-
7
-
-
85017739332
-
Phase 1/2 study of TH-302, investigational hypoxia-activated prodrug, and bevacizumab in patients with bevacizumab-refractory recurrent glioblastoma
-
Brenner A.J., Floyd J., Eng C., Kroll S., Fichtel L., Gruslova A., Lodi A., Tiziani S. Phase 1/2 study of TH-302, investigational hypoxia-activated prodrug, and bevacizumab in patients with bevacizumab-refractory recurrent glioblastoma. Neuro Oncol. 2014, 16(S5).
-
(2014)
Neuro Oncol.
, vol.16
-
-
Brenner, A.J.1
Floyd, J.2
Eng, C.3
Kroll, S.4
Fichtel, L.5
Gruslova, A.6
Lodi, A.7
Tiziani, S.8
-
8
-
-
0023201753
-
Patient age, histologic features, and length of survival in patients with glioblastoma multiforme
-
Burger P.C., Green S.B. Patient age, histologic features, and length of survival in patients with glioblastoma multiforme. Cancer 1987, 59(9):1617-1625.
-
(1987)
Cancer
, vol.59
, Issue.9
, pp. 1617-1625
-
-
Burger, P.C.1
Green, S.B.2
-
9
-
-
13444278829
-
Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases
-
Cartier L., Hartley O., Dubois-Dauphin M., Krause K.H. Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases. Brain Res. Brain Res. Rev. 2005, 48(1):16-42.
-
(2005)
Brain Res. Brain Res. Rev.
, vol.48
, Issue.1
, pp. 16-42
-
-
Cartier, L.1
Hartley, O.2
Dubois-Dauphin, M.3
Krause, K.H.4
-
10
-
-
4043184065
-
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
-
Ceradini D.J., Kulkarni A.R., Callaghan M.J., Tepper O.M., Bastidas N., Kleinman M.E., Capla J.M., Galiano R.D., Levine J.P., Gurtner G.C. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat. Med. 2004, 10(8):858-864.
-
(2004)
Nat. Med.
, vol.10
, Issue.8
, pp. 858-864
-
-
Ceradini, D.J.1
Kulkarni, A.R.2
Callaghan, M.J.3
Tepper, O.M.4
Bastidas, N.5
Kleinman, M.E.6
Capla, J.M.7
Galiano, R.D.8
Levine, J.P.9
Gurtner, G.C.10
-
11
-
-
0035937715
-
Regulation of glut1 mRNA by hypoxia-inducible factor-1. Interaction between H-ras and hypoxia
-
Chen C., Pore N., Behrooz A., Ismail-Beigi F., Maity A. Regulation of glut1 mRNA by hypoxia-inducible factor-1. Interaction between H-ras and hypoxia. J. Biol. Chem. 2001, 276(12):9519-9525.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.12
, pp. 9519-9525
-
-
Chen, C.1
Pore, N.2
Behrooz, A.3
Ismail-Beigi, F.4
Maity, A.5
-
12
-
-
0036283219
-
The radiotherapeutic injury-a complex 'wound'
-
Denham J.W., Hauer-Jensen M. The radiotherapeutic injury-a complex 'wound'. Radiother. Oncol. 2002, 63(2):129-145.
-
(2002)
Radiother. Oncol.
, vol.63
, Issue.2
, pp. 129-145
-
-
Denham, J.W.1
Hauer-Jensen, M.2
-
13
-
-
39849102836
-
HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion
-
Du R., Lu K.V., Petritsch C., Liu P., Ganss R., Passegue E., Song H., Vandenberg S., Johnson R.S., Werb Z., Bergers G. HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. Cancer Cell 2008, 13(3):206-220.
-
(2008)
Cancer Cell
, vol.13
, Issue.3
, pp. 206-220
-
-
Du, R.1
Lu, K.V.2
Petritsch, C.3
Liu, P.4
Ganss, R.5
Passegue, E.6
Song, H.7
Vandenberg, S.8
Johnson, R.S.9
Werb, Z.10
Bergers, G.11
-
14
-
-
36749052895
-
Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy
-
Ebos J.M., Lee C.R., Christensen J.G., Mutsaers A.J., Kerbel R.S. Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy. Proc. Natl. Acad. Sci. U. S. A. 2007, 104(43):17069-17074.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, Issue.43
, pp. 17069-17074
-
-
Ebos, J.M.1
Lee, C.R.2
Christensen, J.G.3
Mutsaers, A.J.4
Kerbel, R.S.5
-
15
-
-
70350461699
-
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
-
Friedman H.S., Prados M.D., Wen P.Y., Mikkelsen T., Schiff D., Abrey L.E., Yung W.K., Paleologos N., Nicholas M.K., Jensen R., Vredenburgh J., Huang J., Zheng M., Cloughesy T. Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J. Clin. Oncol. 2009, 27(28):4733-4740.
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.28
, pp. 4733-4740
-
-
Friedman, H.S.1
Prados, M.D.2
Wen, P.Y.3
Mikkelsen, T.4
Schiff, D.5
Abrey, L.E.6
Yung, W.K.7
Paleologos, N.8
Nicholas, M.K.9
Jensen, R.10
Vredenburgh, J.11
Huang, J.12
Zheng, M.13
Cloughesy, T.14
-
16
-
-
79957544947
-
A phase I study of the safety and pharmacokinetics of the hypoxia-activated prodrug TH-302 in combination with doxorubicin in patients with advanced soft tissue sarcoma
-
Ganjoo K.N., Cranmer L.D., Butrynski J.E., Rushing D., Adkins D., Okuno S.H., Lorente G., Kroll S., Langmuir V.K., Chawla S.P. A phase I study of the safety and pharmacokinetics of the hypoxia-activated prodrug TH-302 in combination with doxorubicin in patients with advanced soft tissue sarcoma. Oncology 2011, 80(1-2):50-56.
-
(2011)
Oncology
, vol.80
, Issue.1-2
, pp. 50-56
-
-
Ganjoo, K.N.1
Cranmer, L.D.2
Butrynski, J.E.3
Rushing, D.4
Adkins, D.5
Okuno, S.H.6
Lorente, G.7
Kroll, S.8
Langmuir, V.K.9
Chawla, S.P.10
-
17
-
-
84858235813
-
CXCL12 mediates apoptosis resistance in rat C6 glioma cells
-
Hattermann K., Mentlein R., Held-Feindt J. CXCL12 mediates apoptosis resistance in rat C6 glioma cells. Oncol. Rep. 2012, 27(5):1348-1352.
-
(2012)
Oncol. Rep.
, vol.27
, Issue.5
, pp. 1348-1352
-
-
Hattermann, K.1
Mentlein, R.2
Held-Feindt, J.3
-
18
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi M.E., Diserens A.C., Gorlia T., Hamou M.F., de Tribolet N., Weller M., Kros J.M., Hainfellner J.A., Mason W., Mariani L., Bromberg J.E., Hau P., Mirimanoff R.O., Cairncross J.G., Janzer R.C., Stupp R. MGMT gene silencing and benefit from temozolomide in glioblastoma. N. Engl. J. Med. 2005, 352(10):997-1003.
-
(2005)
N. Engl. J. Med.
, vol.352
, Issue.10
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
Hamou, M.F.4
de Tribolet, N.5
Weller, M.6
Kros, J.M.7
Hainfellner, J.A.8
Mason, W.9
Mariani, L.10
Bromberg, J.E.11
Hau, P.12
Mirimanoff, R.O.13
Cairncross, J.G.14
Janzer, R.C.15
Stupp, R.16
-
19
-
-
77449131347
-
Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth
-
ra73
-
Hitosugi T., Kang S., Vander Heiden M.G., Chung T.W., Elf S., Lythgoe K., Dong S., Lonial S., Wang X., Chen G.Z., Xie J., Gu T.L., Polakiewicz R.D., Roesel J.L., Boggon T.J., Khuri F.R., Gilliland D.G., Cantley L.C., Kaufman J., Chen J. Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth. Sci. Signal. 2009, 2(97):ra73.
-
(2009)
Sci. Signal.
, vol.2
, Issue.97
-
-
Hitosugi, T.1
Kang, S.2
Vander Heiden, M.G.3
Chung, T.W.4
Elf, S.5
Lythgoe, K.6
Dong, S.7
Lonial, S.8
Wang, X.9
Chen, G.Z.10
Xie, J.11
Gu, T.L.12
Polakiewicz, R.D.13
Roesel, J.L.14
Boggon, T.J.15
Khuri, F.R.16
Gilliland, D.G.17
Cantley, L.C.18
Kaufman, J.19
Chen, J.20
more..
-
20
-
-
33747163982
-
Recurrent glioblastoma multiforme: a review of natural history and management options
-
Hou L.C., Veeravagu A., Hsu A.R., Tse V.C. Recurrent glioblastoma multiforme: a review of natural history and management options. Neurosurg. Focus. 2006, 20(4):E5.
-
(2006)
Neurosurg. Focus.
, vol.20
, Issue.4
, pp. E5
-
-
Hou, L.C.1
Veeravagu, A.2
Hsu, A.R.3
Tse, V.C.4
-
21
-
-
84863035912
-
-
Howlader N., Noone A., Krapcho M., Garshel l.J., Miller D., Altekruse S., Kosary C., Yu M., Ruhl J., Tatalovich Z., Mariotto A., Lewis D., Chen H., Feuer E., Cronin K. SEER Cancer Statistics Review 2014, 1975-2011.
-
(2014)
SEER Cancer Statistics Review
, pp. 1975-2011
-
-
Howlader, N.1
Noone, A.2
Krapcho, M.3
Garshel, L.4
Miller, D.5
Altekruse, S.6
Kosary, C.7
Yu, M.8
Ruhl, J.9
Tatalovich, Z.10
Mariotto, A.11
Lewis, D.12
Chen, H.13
Feuer, E.14
Cronin, K.15
-
22
-
-
70350142397
-
Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma
-
Iwamoto F.M., Abrey L.E., Beal K., Gutin P.H., Rosenblum M.K., Reuter V.E., DeAngelis L.M., Lassman A.B. Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma. Neurology 2009, 73(15):1200-1206.
-
(2009)
Neurology
, vol.73
, Issue.15
, pp. 1200-1206
-
-
Iwamoto, F.M.1
Abrey, L.E.2
Beal, K.3
Gutin, P.H.4
Rosenblum, M.K.5
Reuter, V.E.6
DeAngelis, L.M.7
Lassman, A.B.8
-
23
-
-
84876993950
-
Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers
-
Jain R.K. Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers. J. Clin. Oncol. 2013, 31(17):2205-2218.
-
(2013)
J. Clin. Oncol.
, vol.31
, Issue.17
, pp. 2205-2218
-
-
Jain, R.K.1
-
24
-
-
84875755814
-
Influence of metabolism on epigenetics and disease
-
Kaelin W.G., McKnight S.L. Influence of metabolism on epigenetics and disease. Cell 2013, 153(1):56-69.
-
(2013)
Cell
, vol.153
, Issue.1
, pp. 56-69
-
-
Kaelin, W.G.1
McKnight, S.L.2
-
25
-
-
79952740612
-
Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma
-
Keunen O., Johansson M., Oudin A., Sanzey M., Rahim S.A., Fack F., Thorsen F., Taxt T., Bartos M., Jirik R., Miletic H., Wang J., Stieber D., Stuhr L., Moen I., Rygh C.B., Bjerkvig R., Niclou S.P. Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proc. Natl. Acad. Sci. U. S. A. 2011, 108(9):3749-3754.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, Issue.9
, pp. 3749-3754
-
-
Keunen, O.1
Johansson, M.2
Oudin, A.3
Sanzey, M.4
Rahim, S.A.5
Fack, F.6
Thorsen, F.7
Taxt, T.8
Bartos, M.9
Jirik, R.10
Miletic, H.11
Wang, J.12
Stieber, D.13
Stuhr, L.14
Moen, I.15
Rygh, C.B.16
Bjerkvig, R.17
Niclou, S.P.18
-
26
-
-
0035884609
-
Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2
-
Kunkel P., Ulbricht U., Bohlen P., Brockmann M.A., Fillbrandt R., Stavrou D., Westphal M., Lamszus K. Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2. Cancer Res. 2001, 61(18):6624-6628.
-
(2001)
Cancer Res.
, vol.61
, Issue.18
, pp. 6624-6628
-
-
Kunkel, P.1
Ulbricht, U.2
Bohlen, P.3
Brockmann, M.A.4
Fillbrandt, R.5
Stavrou, D.6
Westphal, M.7
Lamszus, K.8
-
27
-
-
80054972501
-
Hypoxia induces peroxisome proliferator-activated receptor alpha (PPARalpha) and lipid metabolism peroxisomal enzymes in human glioblastoma cells
-
Laurenti G., Benedetti E., D'Angelo B., Cristiano L., Cinque B., Raysi S., Alecci M., Ceru M.P., Cifone M.G., Galzio R., Giordano A., Cimini A. Hypoxia induces peroxisome proliferator-activated receptor alpha (PPARalpha) and lipid metabolism peroxisomal enzymes in human glioblastoma cells. J. Cell. Biochem. 2011, 112(12):3891-3901.
-
(2011)
J. Cell. Biochem.
, vol.112
, Issue.12
, pp. 3891-3901
-
-
Laurenti, G.1
Benedetti, E.2
D'Angelo, B.3
Cristiano, L.4
Cinque, B.5
Raysi, S.6
Alecci, M.7
Ceru, M.P.8
Cifone, M.G.9
Galzio, R.10
Giordano, A.11
Cimini, A.12
-
28
-
-
84928382633
-
Acetate supplementation as a means of inducing glioblastoma stem-like cell growth arrest
-
Long P.M., Tighe S.W., Driscoll H.E., Fortner K.A., Viapiano M.S., Jaworski D.M. Acetate supplementation as a means of inducing glioblastoma stem-like cell growth arrest. J. Cell. Physiol. 2015, 230(8):1929-1943.
-
(2015)
J. Cell. Physiol.
, vol.230
, Issue.8
, pp. 1929-1943
-
-
Long, P.M.1
Tighe, S.W.2
Driscoll, H.E.3
Fortner, K.A.4
Viapiano, M.S.5
Jaworski, D.M.6
-
29
-
-
68049093213
-
Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy
-
Lucio-Eterovic A.K., Piao Y., de Groot J.F. Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy. Clin. Cancer Res. 2009, 15(14):4589-4599.
-
(2009)
Clin. Cancer Res.
, vol.15
, Issue.14
, pp. 4589-4599
-
-
Lucio-Eterovic, A.K.1
Piao, Y.2
de Groot, J.F.3
-
30
-
-
84919905682
-
Acetate fuels the cancer engine
-
Lyssiotis C.A., Cantley L.C. Acetate fuels the cancer engine. Cell 2014, 159(7):1492-1494.
-
(2014)
Cell
, vol.159
, Issue.7
, pp. 1492-1494
-
-
Lyssiotis, C.A.1
Cantley, L.C.2
-
31
-
-
80052182327
-
Radioresistance of glioma stem cells: intrinsic characteristic or property of the 'microenvironment-stem cell unit'?
-
Mannino M., Chalmers A.J. Radioresistance of glioma stem cells: intrinsic characteristic or property of the 'microenvironment-stem cell unit'?. Mol. Oncol. 2011, 5(4):374-386.
-
(2011)
Mol. Oncol.
, vol.5
, Issue.4
, pp. 374-386
-
-
Mannino, M.1
Chalmers, A.J.2
-
32
-
-
84919903877
-
Acetate is a bioenergetic substrate for human glioblastoma and brain metastases
-
Mashimo T., Pichumani K., Vemireddy V., Hatanpaa K.J., Singh D.K., Sirasanagandla S., Nannepaga S., Piccirillo S.G., Kovacs Z., Foong C., Huang Z., Barnett S., Mickey B.E., DeBerardinis R.J., Tu B.P., Maher E.A., Bachoo R.M. Acetate is a bioenergetic substrate for human glioblastoma and brain metastases. Cell 2014, 159(7):1603-1614.
-
(2014)
Cell
, vol.159
, Issue.7
, pp. 1603-1614
-
-
Mashimo, T.1
Pichumani, K.2
Vemireddy, V.3
Hatanpaa, K.J.4
Singh, D.K.5
Sirasanagandla, S.6
Nannepaga, S.7
Piccirillo, S.G.8
Kovacs, Z.9
Foong, C.10
Huang, Z.11
Barnett, S.12
Mickey, B.E.13
DeBerardinis, R.J.14
Tu, B.P.15
Maher, E.A.16
Bachoo, R.M.17
-
33
-
-
0031742365
-
Regional tumor oxygen tension: fluorine echo planar imaging of hexafluorobenzene reveals heterogeneity of dynamics
-
Mason R.P., Hunjan S., Le D., Constantinescu A., Barker B.R., Wong P.S., Peschke P., Hahn E.W., Antich P.P. Regional tumor oxygen tension: fluorine echo planar imaging of hexafluorobenzene reveals heterogeneity of dynamics. Int. J. Radiat. Oncol. Biol. Phys. 1998, 42(4):747-750.
-
(1998)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.42
, Issue.4
, pp. 747-750
-
-
Mason, R.P.1
Hunjan, S.2
Le, D.3
Constantinescu, A.4
Barker, B.R.5
Wong, P.S.6
Peschke, P.7
Hahn, E.W.8
Antich, P.P.9
-
34
-
-
77952863838
-
Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres
-
Mendez O., Zavadil J., Esencay M., Lukyanov Y., Santovasi D., Wang S.C., Newcomb E.W., Zagzag D. Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres. Mol. Cancer 2010, 9:133.
-
(2010)
Mol. Cancer
, vol.9
, pp. 133
-
-
Mendez, O.1
Zavadil, J.2
Esencay, M.3
Lukyanov, Y.4
Santovasi, D.5
Wang, S.C.6
Newcomb, E.W.7
Zagzag, D.8
-
35
-
-
85017745736
-
Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302
-
Meng F., Evans J.W., Bhupathi D., Banica M., Lan L., Lorente G., Duan J.X., Cai X., Mowday A.M., Guise C.P., Maroz A., Anderson R.F., Patterson A.V., Stachelek G.C., Glazer P.M., Matteucci M.D., Hart C.P. Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302 2015, Mol. Cancer Ther.
-
(2015)
Mol. Cancer Ther
-
-
Meng, F.1
Evans, J.W.2
Bhupathi, D.3
Banica, M.4
Lan, L.5
Lorente, G.6
Duan, J.X.7
Cai, X.8
Mowday, A.M.9
Guise, C.P.10
Maroz, A.11
Anderson, R.F.12
Patterson, A.V.13
Stachelek, G.C.14
Glazer, P.M.15
Matteucci, M.D.16
Hart, C.P.17
-
36
-
-
35648945337
-
CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature
-
Miao Z., Luker K.E., Summers B.C., Berahovich R., Bhojani M.S., Rehemtulla A., Kleer C.G., Essner J.J., Nasevicius A., Luker G.D., Howard M.C., Schall T.J. CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature. Proc. Natl. Acad. Sci. U. S. A. 2007, 104(40):15735-15740.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, Issue.40
, pp. 15735-15740
-
-
Miao, Z.1
Luker, K.E.2
Summers, B.C.3
Berahovich, R.4
Bhojani, M.S.5
Rehemtulla, A.6
Kleer, C.G.7
Essner, J.J.8
Nasevicius, A.9
Luker, G.D.10
Howard, M.C.11
Schall, T.J.12
-
37
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
Muller A., Homey B., Soto H., Ge N., Catron D., Buchanan M.E., McClanahan T., Murphy E., Yuan W., Wagner S.N., Barrera J.L., Mohar A., Verastegui E., Zlotnik A. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001, 410(6824):50-56.
-
(2001)
Nature
, vol.410
, Issue.6824
, pp. 50-56
-
-
Muller, A.1
Homey, B.2
Soto, H.3
Ge, N.4
Catron, D.5
Buchanan, M.E.6
McClanahan, T.7
Murphy, E.8
Yuan, W.9
Wagner, S.N.10
Barrera, J.L.11
Mohar, A.12
Verastegui, E.13
Zlotnik, A.14
-
38
-
-
0033646431
-
CXCR4: chemokine receptor extraordinaire
-
Murdoch C. CXCR4: chemokine receptor extraordinaire. Immunol. Rev. 2000, 177:175-184.
-
(2000)
Immunol. Rev.
, vol.177
, pp. 175-184
-
-
Murdoch, C.1
-
39
-
-
72849115544
-
Development of HIF-1 inhibitors for cancer therapy
-
Onnis B., Rapisarda A., Melillo G. Development of HIF-1 inhibitors for cancer therapy. J. Cell. Mol. Med. 2009, 13(9A):2780-2786.
-
(2009)
J. Cell. Mol. Med.
, vol.13
, Issue.9 A
, pp. 2780-2786
-
-
Onnis, B.1
Rapisarda, A.2
Melillo, G.3
-
40
-
-
84929620816
-
CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011
-
Ostrom Q.T., Gittleman H., Liao P., Rouse C., Chen Y., Dowling J., Wolinsky Y., Kruchko C., Barnholtz-Sloan J. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. Neuro Oncol. 2014, 16(4).
-
(2014)
Neuro Oncol.
, vol.16
, Issue.4
-
-
Ostrom, Q.T.1
Gittleman, H.2
Liao, P.3
Rouse, C.4
Chen, Y.5
Dowling, J.6
Wolinsky, Y.7
Kruchko, C.8
Barnholtz-Sloan, J.9
-
41
-
-
84929620816
-
CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011
-
iv1-iv63
-
Ostrom Q.T., Gittleman H., Liao P., Rouse C., Chen Y., Dowling J., Wolinsky Y., Kruchko C., Barnholtz-Sloan J. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. Neuro Oncol. 2014, 16(Suppl. 4):iv1-iv63.
-
(2014)
Neuro Oncol.
, vol.16
-
-
Ostrom, Q.T.1
Gittleman, H.2
Liao, P.3
Rouse, C.4
Chen, Y.5
Dowling, J.6
Wolinsky, Y.7
Kruchko, C.8
Barnholtz-Sloan, J.9
-
42
-
-
0026683004
-
Very long-chain fatty acids in peroxisomal disease
-
Poulos A., Beckman K., Johnson D.W., Paton B.C., Robinson B.S., Sharp P., Usher S., Singh H. Very long-chain fatty acids in peroxisomal disease. Adv. Exp. Med. Biol. 1992, 318:331-340.
-
(1992)
Adv. Exp. Med. Biol.
, vol.318
, pp. 331-340
-
-
Poulos, A.1
Beckman, K.2
Johnson, D.W.3
Paton, B.C.4
Robinson, B.S.5
Sharp, P.6
Usher, S.7
Singh, H.8
-
43
-
-
0025650261
-
Importance of thiols in the reductive binding of 2-nitroimidazoles to macromolecules
-
Raleigh J.A., Koch C.J. Importance of thiols in the reductive binding of 2-nitroimidazoles to macromolecules. Biochem. Pharmacol. 1990, 40(11):2457-2464.
-
(1990)
Biochem. Pharmacol.
, vol.40
, Issue.11
, pp. 2457-2464
-
-
Raleigh, J.A.1
Koch, C.J.2
-
44
-
-
0035253549
-
Semiquantitative immunohistochemical analysis for hypoxia in human tumors
-
Raleigh J.A., Chou S.C., Bono E.L., Thrall D.E., Varia M.A. Semiquantitative immunohistochemical analysis for hypoxia in human tumors. Int. J. Radiat. Oncol. Biol. Phys. 2001, 49(2):569-574.
-
(2001)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.49
, Issue.2
, pp. 569-574
-
-
Raleigh, J.A.1
Chou, S.C.2
Bono, E.L.3
Thrall, D.E.4
Varia, M.A.5
-
45
-
-
33746696738
-
'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis
-
Rong Y., Durden D.L., Van Meir E.G., Brat D.J. 'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis. J. Neuropathol. Exp. Neurol. 2006, 65(6):529-539.
-
(2006)
J. Neuropathol. Exp. Neurol.
, vol.65
, Issue.6
, pp. 529-539
-
-
Rong, Y.1
Durden, D.L.2
Van Meir, E.G.3
Brat, D.J.4
-
46
-
-
84949728981
-
Phase I/II study of TH-302 in combination with docetaxel in patients with solid tumors including NSCLC and castrate-resistant prostate cancer (CRPC). 2010 ASCO Annual Meeting
-
(abstr e13527)
-
Sankhala K.K., Chiorean E.G., Armstrong A.J., Borad M.J., Traynor A.M., Gadgeel S.M., Langmuir V.K., Eng C., Kroll S., Burris H. Phase I/II study of TH-302 in combination with docetaxel in patients with solid tumors including NSCLC and castrate-resistant prostate cancer (CRPC). 2010 ASCO Annual Meeting. J. Clin. Oncol. 2010, 28. (suppl; abstr e13527).
-
(2010)
J. Clin. Oncol.
, vol.28
-
-
Sankhala, K.K.1
Chiorean, E.G.2
Armstrong, A.J.3
Borad, M.J.4
Traynor, A.M.5
Gadgeel, S.M.6
Langmuir, V.K.7
Eng, C.8
Kroll, S.9
Burris, H.10
-
47
-
-
38349155463
-
Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan
-
Sathornsumetee S., Cao Y., Marcello J.E., Herndon J.E., McLendon R.E., Desjardins A., Friedman H.S., Dewhirst M.W., Vredenburgh J.J., Rich J.N. Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan. J. Clin. Oncol. 2008, 26(2):271-278.
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.2
, pp. 271-278
-
-
Sathornsumetee, S.1
Cao, Y.2
Marcello, J.E.3
Herndon, J.E.4
McLendon, R.E.5
Desjardins, A.6
Friedman, H.S.7
Dewhirst, M.W.8
Vredenburgh, J.J.9
Rich, J.N.10
-
48
-
-
84949728245
-
Phase I/II study of TH-302 in combination with gemcitabine in patients with solid tumors including advanced pancreatic cancer. 2010 ASCO Annual Meeting
-
(abstr e13519)
-
Schelman W.R. Phase I/II study of TH-302 in combination with gemcitabine in patients with solid tumors including advanced pancreatic cancer. 2010 ASCO Annual Meeting. J. Clin. Oncol. 2010, (suppl; abstr e13519).
-
(2010)
J. Clin. Oncol.
-
-
Schelman, W.R.1
-
49
-
-
0030477745
-
Mammalian peroxisomes: metabolism of oxygen and reactive oxygen species
-
Singh I. Mammalian peroxisomes: metabolism of oxygen and reactive oxygen species. Ann. N. Y. Acad. Sci. 1996, 804:612-627.
-
(1996)
Ann. N. Y. Acad. Sci.
, vol.804
, pp. 612-627
-
-
Singh, I.1
-
50
-
-
52049120148
-
Regional hypoxia in glioblastoma multiforme quantified with [18F]fluoromisonidazole positron emission tomography before radiotherapy: correlation with time to progression and survival
-
Spence A.M., Muzi M., Swanson K.R., O'Sullivan F., Rockhill J.K., Rajendran J.G., Adamsen T.C., Link J.M., Swanson P.E., Yagle K.J., Rostomily R.C., Silbergeld D.L., Krohn K.A. Regional hypoxia in glioblastoma multiforme quantified with [18F]fluoromisonidazole positron emission tomography before radiotherapy: correlation with time to progression and survival. Clin. Cancer Res. 2008, 14(9):2623-2630.
-
(2008)
Clin. Cancer Res.
, vol.14
, Issue.9
, pp. 2623-2630
-
-
Spence, A.M.1
Muzi, M.2
Swanson, K.R.3
O'Sullivan, F.4
Rockhill, J.K.5
Rajendran, J.G.6
Adamsen, T.C.7
Link, J.M.8
Swanson, P.E.9
Yagle, K.J.10
Rostomily, R.C.11
Silbergeld, D.L.12
Krohn, K.A.13
-
51
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R., Mason W.P., van den Bent M.J., Weller M., Fisher B., Taphoorn M.J., Belanger K., Brandes A.A., Marosi C., Bogdahn U., Curschmann J., Janzer R.C., Ludwin S.K., Gorlia T., Allgeier A., Lacombe D., Cairncross J.G., Eisenhauer E., Mirimanoff R.O. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 2005, 352(10):987-996.
-
(2005)
N. Engl. J. Med.
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
Gorlia, T.14
Allgeier, A.15
Lacombe, D.16
Cairncross, J.G.17
Eisenhauer, E.18
Mirimanoff, R.O.19
-
52
-
-
84904913239
-
Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): a randomised controlled phase 2 trial
-
Taal W., Oosterkamp H.M., Walenkamp A.M., Dubbink H.J., Beerepoot L.V., Hanse M.C., Buter J., Honkoop A.H., Boerman D., de Vos F.Y., Dinjens W.N., Enting R.H., Taphoorn M.J., van den Berkmortel F.W., Jansen R.L., Brandsma D., Bromberg J.E., van Heuvel I., Vernhout R.M., van der Holt B., van den Bent M.J. Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): a randomised controlled phase 2 trial. Lancet Oncol. 2014, 15(9):943-953.
-
(2014)
Lancet Oncol.
, vol.15
, Issue.9
, pp. 943-953
-
-
Taal, W.1
Oosterkamp, H.M.2
Walenkamp, A.M.3
Dubbink, H.J.4
Beerepoot, L.V.5
Hanse, M.C.6
Buter, J.7
Honkoop, A.H.8
Boerman, D.9
de Vos, F.Y.10
Dinjens, W.N.11
Enting, R.H.12
Taphoorn, M.J.13
van den Berkmortel, F.W.14
Jansen, R.L.15
Brandsma, D.16
Bromberg, J.E.17
van Heuvel, I.18
Vernhout, R.M.19
van der Holt, B.20
van den Bent, M.J.21
more..
-
53
-
-
33846261158
-
Chemokine receptor expression by neural progenitor cells in neurogenic regions of mouse brain
-
Tran P.B., Banisadr G., Ren D., Chenn A., Miller R.J. Chemokine receptor expression by neural progenitor cells in neurogenic regions of mouse brain. J. Comp. Neurol. 2007, 500(6):1007-1033.
-
(2007)
J. Comp. Neurol.
, vol.500
, Issue.6
, pp. 1007-1033
-
-
Tran, P.B.1
Banisadr, G.2
Ren, D.3
Chenn, A.4
Miller, R.J.5
-
54
-
-
84865169609
-
Metabolic pathway alterations that support cell proliferation
-
Vander Heiden M.G., Lunt S.Y., Dayton T.L., Fiske B.P., Israelsen W.J., Mattaini K.R., Vokes N.I., Stephanopoulos G., Cantley L.C., Metallo C.M., Locasale J.W. Metabolic pathway alterations that support cell proliferation. Cold Spring Harb. Symp. Quant. Biol. 2011, 76:325-334.
-
(2011)
Cold Spring Harb. Symp. Quant. Biol.
, vol.76
, pp. 325-334
-
-
Vander Heiden, M.G.1
Lunt, S.Y.2
Dayton, T.L.3
Fiske, B.P.4
Israelsen, W.J.5
Mattaini, K.R.6
Vokes, N.I.7
Stephanopoulos, G.8
Cantley, L.C.9
Metallo, C.M.10
Locasale, J.W.11
-
55
-
-
85017728093
-
Phase I/II study of TH-302 in combination with pemetrexed in patients with solid tumors including NSCLC
-
Vlahovic G., Infante J.R., Mita A.C., Traynor A.M., Molina J.R., Lacouture M.E., Langmuir V.K., Eng C., Kroll S., Borad M.J. Phase I/II study of TH-302 in combination with pemetrexed in patients with solid tumors including NSCLC. 2010 ASCO Annual Meeting 2010.
-
(2010)
2010 ASCO Annual Meeting
-
-
Vlahovic, G.1
Infante, J.R.2
Mita, A.C.3
Traynor, A.M.4
Molina, J.R.5
Lacouture, M.E.6
Langmuir, V.K.7
Eng, C.8
Kroll, S.9
Borad, M.J.10
-
56
-
-
84895803183
-
Inhibition of CXCR7 extends survival following irradiation of brain tumours in mice and rats
-
Walters M.J., Ebsworth K., Berahovich R.D., Penfold M.E., Liu S.C., Al Omran R., Kioi M., Chernikova S.B., Tseng D., Mulkearns-Hubert E.E., Sinyuk M., Ransohoff R.M., Lathia J.D., Karamchandani J., Kohrt H.E., Zhang P., Powers J.P., Jaen J.C., Schall T.J., Merchant M., Recht L., Brown J.M. Inhibition of CXCR7 extends survival following irradiation of brain tumours in mice and rats. Br. J. Cancer 2014, 110(5):1179-1188.
-
(2014)
Br. J. Cancer
, vol.110
, Issue.5
, pp. 1179-1188
-
-
Walters, M.J.1
Ebsworth, K.2
Berahovich, R.D.3
Penfold, M.E.4
Liu, S.C.5
Al Omran, R.6
Kioi, M.7
Chernikova, S.B.8
Tseng, D.9
Mulkearns-Hubert, E.E.10
Sinyuk, M.11
Ransohoff, R.M.12
Lathia, J.D.13
Karamchandani, J.14
Kohrt, H.E.15
Zhang, P.16
Powers, J.P.17
Jaen, J.C.18
Schall, T.J.19
Merchant, M.20
Recht, L.21
Brown, J.M.22
more..
-
57
-
-
42949133032
-
The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer
-
Wang J., Shiozawa Y., Wang J., Wang Y., Jung Y., Pienta K.J., Mehra R., Loberg R., Taichman R.S. The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer. J. Biol. Chem. 2008, 283(7):4283-4294.
-
(2008)
J. Biol. Chem.
, vol.283
, Issue.7
, pp. 4283-4294
-
-
Wang, J.1
Shiozawa, Y.2
Wang, J.3
Wang, Y.4
Jung, Y.5
Pienta, K.J.6
Mehra, R.7
Loberg, R.8
Taichman, R.S.9
-
58
-
-
0024195429
-
DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability
-
Ward J.F. DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability. Prog. Nucleic Acid Res. Mol. Biol. 1988, 35:95-125.
-
(1988)
Prog. Nucleic Acid Res. Mol. Biol.
, vol.35
, pp. 95-125
-
-
Ward, J.F.1
-
59
-
-
79955490434
-
Phase 1 study of the safety, tolerability, and pharmacokinetics of TH-302, a hypoxia-activated prodrug, in patients with advanced solid malignancies
-
Weiss G.J., Infante J.R., Chiorean E.G., Borad M.J., Bendell J.C., Molina J.R., Tibes R., Ramanathan R.K., Lewandowski K., Jones S.F., Lacouture M.E., Langmuir V.K., Lee H., Kroll S., Burris H.A. Phase 1 study of the safety, tolerability, and pharmacokinetics of TH-302, a hypoxia-activated prodrug, in patients with advanced solid malignancies. Clin. Cancer Res. 2011, 17(9):2997-3004.
-
(2011)
Clin. Cancer Res.
, vol.17
, Issue.9
, pp. 2997-3004
-
-
Weiss, G.J.1
Infante, J.R.2
Chiorean, E.G.3
Borad, M.J.4
Bendell, J.C.5
Molina, J.R.6
Tibes, R.7
Ramanathan, R.K.8
Lewandowski, K.9
Jones, S.F.10
Lacouture, M.E.11
Langmuir, V.K.12
Lee, H.13
Kroll, S.14
Burris, H.A.15
-
60
-
-
70350225520
-
Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer
-
Xu L., Duda D.G., di Tomaso E., Ancukiewicz M., Chung D.C., Lauwers G.Y., Samuel R., Shellito P., Czito B.G., Lin P.C., Poleski M., Bentley R., Clark J.W., Willett C.G., Jain R.K. Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer. Cancer Res. 2009, 69(20):7905-7910.
-
(2009)
Cancer Res.
, vol.69
, Issue.20
, pp. 7905-7910
-
-
Xu, L.1
Duda, D.G.2
di Tomaso, E.3
Ancukiewicz, M.4
Chung, D.C.5
Lauwers, G.Y.6
Samuel, R.7
Shellito, P.8
Czito, B.G.9
Lin, P.C.10
Poleski, M.11
Bentley, R.12
Clark, J.W.13
Willett, C.G.14
Jain, R.K.15
-
61
-
-
48749124404
-
Hypoxia- and vascular endothelial growth factor-induced stromal cell-derived factor-1alpha/CXCR4 expression in glioblastomas: one plausible explanation of Scherer's structures
-
Zagzag D., Esencay M., Mendez O., Yee H., Smirnova I., Huang Y., Chiriboga L., Lukyanov E., Liu M., Newcomb E.W. Hypoxia- and vascular endothelial growth factor-induced stromal cell-derived factor-1alpha/CXCR4 expression in glioblastomas: one plausible explanation of Scherer's structures. Am. J. Pathol. 2008, 173(2):545-560.
-
(2008)
Am. J. Pathol.
, vol.173
, Issue.2
, pp. 545-560
-
-
Zagzag, D.1
Esencay, M.2
Mendez, O.3
Yee, H.4
Smirnova, I.5
Huang, Y.6
Chiriboga, L.7
Lukyanov, E.8
Liu, M.9
Newcomb, E.W.10
-
62
-
-
67649946279
-
Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study
-
Zhu A.X., Sahani D.V., Duda D.G., di Tomaso E., Ancukiewicz M., Catalano O.A., Sindhwani V., Blaszkowsky L.S., Yoon S.S., Lahdenranta J., Bhargava P., Meyerhardt J., Clark J.W., Kwak E.L., Hezel A.F., Miksad R., Abrams T.A., Enzinger P.C., Fuchs C.S., Ryan D.P., Jain R.K. Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study. J. Clin. Oncol. 2009, 27(18):3027-3035.
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.18
, pp. 3027-3035
-
-
Zhu, A.X.1
Sahani, D.V.2
Duda, D.G.3
di Tomaso, E.4
Ancukiewicz, M.5
Catalano, O.A.6
Sindhwani, V.7
Blaszkowsky, L.S.8
Yoon, S.S.9
Lahdenranta, J.10
Bhargava, P.11
Meyerhardt, J.12
Clark, J.W.13
Kwak, E.L.14
Hezel, A.F.15
Miksad, R.16
Abrams, T.A.17
Enzinger, P.C.18
Fuchs, C.S.19
Ryan, D.P.20
Jain, R.K.21
more..
|