Transient transforming growth factor β1 modulation in monocytes and natural killer cells following plasma or plasma-platelet apheresis donation procedures

Blood Transfusion

Volumn 13, Issue 4, 2015, Pages 684-686

  Ghio, Massimo ^a   Contini, Paola ^a   Ubezio, Gianluca ^a   Ansaldi, Filippo ^a   Setti, Maurizio ^a   Tripodi, Gino ^b  

^a UNIVERSITY OF GENOA   (Italy)

^b G GASLINI INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; HLA A1 ANTIGEN; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1; HLA ANTIGEN CLASS 1; POLYMER; PROTEIN BINDING;

APHERESIS; BLOOD DONOR; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNOFLUORESCENCE TEST; IMMUNOMODULATION; LETTER; LEUKOCYTE ACTIVATION; MALE; MONOCYTE; NATURAL KILLER CELL; POLYMERASE CHAIN REACTION; ADSORPTION; BIOSYNTHESIS; BLOOD; CENTRIFUGATION; CHEMISTRY; DEVICES; EQUIPMENT DESIGN; GENETICS; IMMUNOLOGY; PLASMA; PLASMAPHERESIS; PROCEDURES; THROMBOCYTOPHERESIS; TIME FACTOR; UPREGULATION;

ADSORPTION; BLOOD DONORS; CENTRIFUGATION; EQUIPMENT DESIGN; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNOMODULATION; KILLER CELLS, NATURAL; MALE; MONOCYTES; PLASMA; PLASMAPHERESIS; PLATELETPHERESIS; POLYMERS; PROTEIN BINDING; RNA, MESSENGER; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 84949682671     PISSN: 17232007     EISSN: None     Source Type: Journal    
DOI: 10.2450/2015.0258-14     Document Type: Letter

References (5)

1. Ghio M, Contini P, Ansaldi F, et al. Immunomodulation due to plasma or plasma-platelet apheresis donation: Events occurring during donation procedures. J Clin Apher 2015; 30; 204-11.
2. Ghio M, Contini P, Ansaldi F, et al. A possible role of soluble HLA-I molecule in the immunomodulatory effects of therapeutic apheresis. Blood Transfus 2014; 12 (Suppl 1): s167-9.
3. Ghio M, Contini P, Ansaldi F, et al. Donor neutrophil activation and transforming growth factor-ß1 modulation induced by donor apheresis procedures. Blood Transfusion 2014; 12: 615-7.
4. Ghio M, Contini P, Negrini S, et al. Down regulation of human natural killer cell-mediated cytolysis induced by blood transfusion: role of transforming growth factor-β(1), soluble Fas ligand, and soluble class I human leukocyte antigen. Transfusion 2011; 51: 1567-73.
5. Ghio M, Contini P, Negrini S, et al. Soluble HLA-I-mediated secretion of TGF-beta1 by human NK cells and consequent down-regulation of anti-tumor cytolytic activity. Eur J Immunol 2009; 39: 3459-68.