Chemopreventive effect of oleuropein in colitis-associated colorectal cancer in c57bl/6 mice

Molecular Nutrition and Food Research

Volumn 60, Issue 2, 2016, Pages 242-255

  Giner, Elisa ^a   Recio, M Carmen ^a   Ríos, José Luis ^a   Cerdá Nicolás, José Miguel ^a   Giner, Rosa María ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Azoxymethane dextran sulphate sodium; Chemoprevention; Colitis associated colorectal cancer; Oleuropein; Th17 response

Indexed keywords

ANTINEOPLASTIC AGENT; AZOXYMETHANE; CYTOKINE; DEXTRAN SULFATE; IRIDOID; OLEUROPEIN;

ANIMAL; C57BL MOUSE; CELL PROLIFERATION; CHEMICALLY INDUCED; COLITIS; COLON; COLORECTAL NEOPLASMS; COMPLICATION; DRUG EFFECTS; FEMALE; METABOLISM; NEOPLASMS, EXPERIMENTAL; PATHOLOGY; TH17 CELL;

ANIMALS; ANTICARCINOGENIC AGENTS; AZOXYMETHANE; CELL PROLIFERATION; COLITIS; COLON; COLORECTAL NEOPLASMS; CYTOKINES; DEXTRAN SULFATE; FEMALE; IRIDOIDS; MICE, INBRED C57BL; NEOPLASMS, EXPERIMENTAL; TH17 CELLS;

EID: 84949670206     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201500605     Document Type: Article

References (39)

1. Shimizu, M., Kochi, T., Shirakami, Y., Genovese, S. et al., A newly synthesized compound, 4'-geranyloxyferulic acid-N (omega)-nitro-L-arginine methyl ester suppresses inflammation-associated colorectal carcinogenesis in male mice. Int. J. Cancer 2014, 135, 774-784.
2. Siegel, R., Desantis, C., Jemal, A., Colorectal cancer statistics, 2014. C.A. Cancer J. Clin. 2014, 64, 104-117.
3. Dyson, J.-K., Matthew, D.-R., Colorectal cancer in inflammatory bowel disease: what is the real magnitude of the risk? World J. Gastroenterol. 2012, 18, 3839-3848.
4. Lavi, I., Nimri, L., Levinson, D., Peri, I. et al., Glucans from the edible mushroom Pleurotus pulmonarius inhibit colitis-associated colon carcinogenesis in mice. Gastroenterology 2012, 47, 504-518.
5. Grivennikov, S.-I., Inflammation and colorectal cancer: colitis-associated neoplasia. Semin. Immunopathol. 2013, 35, 229-244.
6. Marion, J.-F., Colorectal cancer in colitis: a relic of the past? Inflamm. Bowel Dis. 2015, 21, 699-702.
7. Clapper, M.-L., Cooper, H.-S., Chang, W.-C., Dextran sulfate sodium-induced colitis-associated neoplasia: a promising model for the development of chemopreventive interventions. Acta Pharmacol. Sin. 2007, 28, 1450-1459.
8. Biasi, F., Astegiano, M., Maina, M., Leonarduzzi, G. et al., Polyphenol supplementation as a complementary medicinal approach to treating inflammatory bowel disease. Curr. Med. Chem. 2011, 18, 4851-4865.
9. Rudolf, E., Andelová, H., Cervinka, M., Polyphenolic compounds in chemoprevention of colon cancer-targets and signaling pathways. Anticancer Agents Med. Chem. 2007, 7, 559-575.
10. Impellizzeri, D., Esposito, E., Mazzon, E., Paterniti, I. et al., The effects of oleuropein aglycone, an olive oil compound, in a mouse model of carrageenan-induced pleurisy. Clin. Nutr. 2011, 30, 533-540.
11. Impellizzeri, D., Esposito, E., Mazzon, E., Paterniti, I. et al., Oleuropein aglycone, an olive oil compound, ameliorates development of arthritis caused by injection of collagen type II in mice. J. Pharmacol. Exp. Ther. 2011, 339, 859-869.
12. Impellizzeri, D., Esposito, E., Mazzon, E., Paterniti, I. et al., The effects of a polyphenol present in olive oil, oleuropein aglycone, in an experimental model of spinal cord injury in mice. Biochem. Pharmacol. 2012, 83, 1413-1426.
13. Giner, E., Recio, M.-C., Ríos, J.-L., Giner, R.-M., Oleuropein protects against dextran sodium sulfate-induced chronic colitis in mice. J. Nat. Prod. 2013, 76, 1113-1120.
14. Giner, E., Andújar, I., Recio, M.-C., Ríos, J.-L. et al., Oleuropein ameliorates acute colitis in mice. J. Agric. Food Chem. 2011, 59, 12882-12892.
15. Acquaviva, R., Di Giacomo, C., Sorrenti, V., Galvano, F. et al., Antiproliferative effect of oleuropein in prostate cell lines. Int. J. Oncol. 2012, 41, 31-38.
16. Elamin, M.-H., Daghestani, M.-H., Omer, S.-A., Elobeid, M.-A. et al., Olive oil oleuropein has anti-breast cancer properties with higher efficiency on ER-negative cells. Food Chem. Toxicol. 2013, 53, 310-316.
17. Yao, J., Wu, J., Yang, X., Yang, J. et al., Oleuropein induced apoptosis in HeLa cells via a mitochondrial apoptotic cascade associated with activation of the c-Jun NH2-terminal kinase. J. Pharmacol. Sci. 2014, 125, 300-311.
18. Cárdeno, A., Sánchez-Hidalgo, M., Rosillo, M.-A., Alarcón de la Lastra, C., Oleuropein, a secoiridoid derived from olive tree, inhibits the proliferation of human colorectal cancer cell through downregulation of HIF-1α;. Nutr. Cancer 2013, 65, 147-156.
19. Omrane, I., Benammar-Elgaaied, A., The immune microenvironment of the colorectal tumor: involvement of immunity genes and microRNAs belonging to the TH17 pathway. Biochim. Biophys. Acta 2015, 1856, 28-38.
20. Yashiro, M., Ulcerative colitis-associated colorectal cancer. World J. Gastroenterol. 2014, 20, 16389-16397.
21. Clapper, M.-L., Gary, M.-A., Coudry, R.-A., Litwin, S. et al., 5-aminosalicylic acid inhibits colitis-associated colorectal dysplasias in the mouse model of azoxymethane/dextran sulfate sodium-induced colitis. Inflamm. Bowel Dis. 2008, 14, 1341-1347.
22. Bernini, R., Merendinob, N., Romanic, A., Velotti, F., Naturally occurring hydroxytyrosol: synthesis and anticancer potential. Cur. Med. Chem. 2013, 20, 655-670.
23. Sánchez-Fidalgo, S., Cárdeno, A., Sánchez-Hidalgo, M., Aparicio-Soto, M., Alarcón de la Lastra, C., Dietary extra virgin olive oil polyphenols supplementation modulates DSS-induced chronic colitis in mice. J. Nutr. Biochem. 2013, 24, 1401-1413.
24. Sánchez-Fidalgo, S., Villegasa, I., Cárdeno, A., Talero, E. et al., Extra-virgin olive oil-enriched diet modulates DSS-colitis-associated colon carcinogenesis in mice. Clin. Nutr. 2010, 29, 663-673.
25. Hauso, Ø., Martinsen, T.-C., Waldum, H., 5-Aminosalicylic acid, a specific drug for ulcerative colitis. Scand. J. Gastroenterol. 2015, 50, 933-941.
26. Feagan, B.-G., Macdonald, J.-K., Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis. Cochrane Database Syst. Rev. 2012, 10, Article ID CD000543.
27. D'Argenio, G., Cosenza, V., Sorrentini, I., De Ritis, F. et al., Butyrate, mesalamine, and factor XIII in experimental colitis in the rat: effects on transglutaminase activity. Gastroenterology 1994, 106, 399-404.
28. Fedorak, R.-N., Empey, L.-R., MacArthur, C., Jewell, L.-D., Misoprostol provides a colonic mucosal protective effect during acetic acid-induced colitis in rats. Gastroenterology 1990, 98, 615-625.
29. Ramírez-Alcántara, V., Montrose, M.-H., Acute murine colitis reduces colonic 5-aminosalicylic acid metabolism by regulation of N-acetyltransferase-2. Am. J. Physiol. Gastrointest. Liver Physiol. 2014, 306, G1002-G1010.
30. Takahashi, M., Fukuda, K., Sugimura, T., Wakabayashi, K., Beta-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors. Cancer Res. 1998, 58, 42-46.
31. Aust, D.-E., Terdiman, J.-P., Willenbucher, R.-F., Chew, K. et al., Altered distribution of beta-catenin, and its binding proteins E-cadherin and APC, in ulcerative colitis-related colorectal cancers. Mod. Pathol. 2001, 14, 29-39.
32. Pandurangan, A.-K., Potential targets for prevention of colorectal cancer: a focus on PI3K/Akt/mTOR and Wnt pathways. Asian Pac. J. Cancer Prev. 2013, 14, 2201-2205.
33. Li, W., Hua, B., Saud, S.-M., Lin, H. et al., Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice. Mol. Carcinog. 2014, 54, 1096-1109.
34. Greten, F.-R., Eckmann, L., Greten, T.-F., Park, J.-M. et al., IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 2004, 118, 285-296.
35. Balkwill, F., Tumour necrosis factor and cancer. Nat. Rev. Cancer 2009, 9, 361-371.
36. Atreya, R., Neurath, M.-F., Involvement of IL-6 in the pathogenesis of inflammatory bowel disease and colon cancer. Clin. Rev. Allergy Immunol. 2005, 28, 187-196.
37. Kim, S.-Y., Kang, J.-W., Song, X., Kim, B.-K. et al., Role of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells. Cell Signal. 2013, 25, 961-969.
38. Watson A.-J., An overview of apoptosis and the prevention of colorectal cancer. Crit. Rev. Oncol. Hematol. 2006, 57, 107-121.
39. Hyun, Y.-S., Han, D.-S., Lee, A.-R., Eun, C.-S. et al., Role of IL-17A in the development of colitis associated cancer. Carcinogenesis 2012, 33, 931-936.