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Volumn 6, Issue OCT, 2015, Pages

Syntenin controls migration, growth, proliferation, and cell cycle progression in cancer cells

Author keywords

Cancer cell growth; Cancer cell migration; Cancer cell proliferation; Cell cycle; PDZ proteins; Syndecan; Syntenin

Indexed keywords

CYCLIN D2; CYCLIN DEPENDENT KINASE 4; RETINOBLASTOMA PROTEIN; SYNTENIN;

EID: 84949664047     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2015.00241     Document Type: Article
Times cited : (31)

References (31)
  • 2
    • 46649120323 scopus 로고    scopus 로고
    • The ins and outs of syntenin, a multifunctional intracellular adaptor protein
    • Beekman, J. M., and Coffer, P. J. (2008). The ins and outs of syntenin, a multifunctional intracellular adaptor protein. J. Cell Sci. 121, 1349-1355. doi: 10.1242/jcs.026401
    • (2008) J. Cell Sci. , vol.121 , pp. 1349-1355
    • Beekman, J.M.1    Coffer, P.J.2
  • 3
    • 77952953786 scopus 로고    scopus 로고
    • Src kinase activation is mandatory for MDA-9/syntenin-mediated activation of nuclear factor-kappaB
    • Boukerche, H., Aissaoui, H., Prévost, C., Hirbec, H., Das, S. K., Su, Z.-Z., et al. (2010). Src kinase activation is mandatory for MDA-9/syntenin-mediated activation of nuclear factor-kappaB. Oncogene 29, 3054-3066. doi: 10.1038/onc.2010.65
    • (2010) Oncogene , vol.29 , pp. 3054-3066
    • Boukerche, H.1    Aissaoui, H.2    Prévost, C.3    Hirbec, H.4    Das, S.K.5    Su, Z.-Z.6
  • 4
    • 33847748493 scopus 로고    scopus 로고
    • mda-9/Syntenin regulates the metastatic phenotype in human melanoma cells by activating nuclear factor-kappaB
    • Boukerche, H., Su, Z., Emdad, L., Sarkar, D., and Fisher, P. B. (2007). mda-9/Syntenin regulates the metastatic phenotype in human melanoma cells by activating nuclear factor-kappaB. Cancer Res. 67, 1812-1822. doi: 10.1158/0008-5472.CAN-06-3875
    • (2007) Cancer Res. , vol.67 , pp. 1812-1822
    • Boukerche, H.1    Su, Z.2    Emdad, L.3    Sarkar, D.4    Fisher, P.B.5
  • 5
    • 57349141863 scopus 로고    scopus 로고
    • mda-9/Syntenin promotes metastasis in human melanoma cells by activating c-Src
    • Boukerche, H., Su, Z., Prévot, C., Sarkar, D., and Fisher, P. B. (2008). mda-9/Syntenin promotes metastasis in human melanoma cells by activating c-Src. Proc. Natl. Acad. Sci. U.S.A. 105, 15914-15919. doi: 10.1073/pnas.0808171105
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 15914-15919
    • Boukerche, H.1    Su, Z.2    Prévot, C.3    Sarkar, D.4    Fisher, P.B.5
  • 6
    • 28244435950 scopus 로고    scopus 로고
    • mda-9/Syntenin: a positive regulator of melanoma metastasis
    • Boukerche, H., Su, Z.-Z., Emdad, L., Baril, P., Balme, B., Thomas, L., et al. (2005). mda-9/Syntenin: a positive regulator of melanoma metastasis. Cancer Res. 65, 10901-10911. doi: 10.1158/0008-5472.CAN-05-1614
    • (2005) Cancer Res. , vol.65 , pp. 10901-10911
    • Boukerche, H.1    Su, Z.-Z.2    Emdad, L.3    Baril, P.4    Balme, B.5    Thomas, L.6
  • 7
    • 84872531704 scopus 로고    scopus 로고
    • MDA-9/Syntenin and IGFBP-2 Promote angiogenesis in human melanoma
    • Das, S. K., Bhutia, S. K., Azab, B., Kegelman, T. P., Peachy, L., Santhekadur, P. K., et al. (2013). MDA-9/Syntenin and IGFBP-2 Promote angiogenesis in human melanoma. Cancer Res. 73, 844-854. doi: 10.1158/0008-5472.CAN-12-1681
    • (2013) Cancer Res. , vol.73 , pp. 844-854
    • Das, S.K.1    Bhutia, S.K.2    Azab, B.3    Kegelman, T.P.4    Peachy, L.5    Santhekadur, P.K.6
  • 8
    • 84883317387 scopus 로고    scopus 로고
    • Novel role of MDA-9/syntenin in regulating urothelial cell proliferation by modulating egfr signaling
    • Dasgupta, S., Menezes, M., Das, S. K., Emdad, L., Janjic, A., Bhatia, S., et al. (2013). Novel role of MDA-9/syntenin in regulating urothelial cell proliferation by modulating egfr signaling. Clin. Cancer Res. 19, 4621-4633. doi: 10.1158/1078-0432.CCR-13-0585
    • (2013) Clin. Cancer Res. , vol.19 , pp. 4621-4633
    • Dasgupta, S.1    Menezes, M.2    Das, S.K.3    Emdad, L.4    Janjic, A.5    Bhatia, S.6
  • 9
    • 34147094240 scopus 로고    scopus 로고
    • The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge
    • Dow, L. E., Kauffman, J. S., Caddy, J., Zarbalis, K., Peterson, A. S., Jane, S. M., et al. (2007). The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge. Oncogene 26, 2272-2282. doi: 10.1038/sj.onc.1210016
    • (2007) Oncogene , vol.26 , pp. 2272-2282
    • Dow, L.E.1    Kauffman, J.S.2    Caddy, J.3    Zarbalis, K.4    Peterson, A.S.5    Jane, S.M.6
  • 10
    • 84942828853 scopus 로고    scopus 로고
    • Syntenin and syndecan in the biogenesis of exosomes
    • Friand, V., David, G., and Zimmermann, P. (2015). Syntenin and syndecan in the biogenesis of exosomes. Biol. Cell 107, 331-341. doi: 10.1111/boc.201500010
    • (2015) Biol. Cell , vol.107 , pp. 331-341
    • Friand, V.1    David, G.2    Zimmermann, P.3
  • 11
    • 21744431575 scopus 로고    scopus 로고
    • The sweet and sour of cancer: glycans as novel therapeutic targets
    • Fuster, M. M., and Esko, J. D. (2005). The sweet and sour of cancer: glycans as novel therapeutic targets. Nat. Rev. Cancer 5, 526-542. doi: 10.1038/nrc1649
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 526-542
    • Fuster, M.M.1    Esko, J.D.2
  • 12
    • 84897865127 scopus 로고    scopus 로고
    • Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2.
    • Ghossoub, R., Lembo, F., Rubio, A., Gaillard, C. B., Bouchet, J., Vitale, N., et al. (2014). Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2. Nat. Commun. 5:3477. doi: 10.1038/ncomms4477
    • (2014) Nat. Commun. , vol.5 , pp. 3477
    • Ghossoub, R.1    Lembo, F.2    Rubio, A.3    Gaillard, C.B.4    Bouchet, J.5    Vitale, N.6
  • 13
    • 0034733733 scopus 로고    scopus 로고
    • Syntenin-syndecan binding requires syndecan-synteny and the co-operation of both PDZ domains of syntenin
    • Grootjans, J. J., Reekmans, G., Ceulemans, H., and David, G. (2000). Syntenin-syndecan binding requires syndecan-synteny and the co-operation of both PDZ domains of syntenin. J. Biol. Chem. 275, 19933-19941. doi: 10.1074/jbc. M002459200
    • (2000) J. Biol. Chem. , vol.275 , pp. 19933-19941
    • Grootjans, J.J.1    Reekmans, G.2    Ceulemans, H.3    David, G.4
  • 15
  • 16
    • 84941254807 scopus 로고    scopus 로고
    • Utilization of the soft agar colony formation assay to identify inhibitors of tumorigenicity in breast cancer cells.
    • Horibata, S., Vo, T. V., Subramanian, V., Thompson, P. R., and Coonrod, S. A. (2015). Utilization of the soft agar colony formation assay to identify inhibitors of tumorigenicity in breast cancer cells. J. Vis. Exp. 20:e52727. doi: 10.3791/52727
    • (2015) J. Vis. Exp. , vol.20
    • Horibata, S.1    Vo, T.V.2    Subramanian, V.3    Thompson, P.R.4    Coonrod, S.A.5
  • 17
    • 84937631806 scopus 로고    scopus 로고
    • Emerging properties of adhesion complexes: what are they and what do they do
    • Humphries, J. D., Paul, N. R., Humphries, M. J., and Morgan, M. R. (2015). Emerging properties of adhesion complexes: what are they and what do they do? Trends Cell Biol. 25, 388-397. doi: 10.1016/j.tcb.2015.02.008
    • (2015) Trends Cell Biol. , vol.25 , pp. 388-397
    • Humphries, J.D.1    Paul, N.R.2    Humphries, M.J.3    Morgan, M.R.4
  • 19
    • 0037071898 scopus 로고    scopus 로고
    • Syntenin is overexpressed and promotes cell migration in metastatic human breast and gastric cancer cell lines
    • Koo, T. H., Lee, J.-J., Kim, E.-M., Kim, K.-W., Kim, H. D., and Lee, J.-H. (2002). Syntenin is overexpressed and promotes cell migration in metastatic human breast and gastric cancer cell lines. Oncogene 21, 4080-4088. doi: 10.1038/sj.onc.1205514
    • (2002) Oncogene , vol.21 , pp. 4080-4088
    • Koo, T.H.1    Lee, J.-J.2    Kim, E.-M.3    Kim, K.-W.4    Kim, H.D.5    Lee, J.-H.6
  • 20
    • 84861182034 scopus 로고    scopus 로고
    • Syntenin, a syndecan adaptor and an Arf6 phosphatidylinositol 4,5-bisphosphate effector, is essential for epiboly and gastrulation cell movements in zebrafish
    • Lambaerts, K., Van Dyck, S., Mortier, E., Ivarsson, Y., Degeest, G., Luyten, A., et al. (2012). Syntenin, a syndecan adaptor and an Arf6 phosphatidylinositol 4,5-bisphosphate effector, is essential for epiboly and gastrulation cell movements in zebrafish. J. Cell Sci. 125, 1129-1140. doi: 10.1242/jcs.089987
    • (2012) J. Cell Sci. , vol.125 , pp. 1129-1140
    • Lambaerts, K.1    Van Dyck, S.2    Mortier, E.3    Ivarsson, Y.4    Degeest, G.5    Luyten, A.6
  • 21
    • 79956194358 scopus 로고    scopus 로고
    • Syndecan-2 cytoplasmic domain regulates colon cancer cell migration via interaction with syntenin-1
    • Lee, H., Kim, Y., Choi, Y., Choi, S., Hong, E., and Oh, E.-S. (2011). Syndecan-2 cytoplasmic domain regulates colon cancer cell migration via interaction with syntenin-1. Biochem. Biophys. Res. Commun. 409, 148-153. doi: 10.1016/j.bbrc.2011.04.135
    • (2011) Biochem. Biophys. Res. Commun. , vol.409 , pp. 148-153
    • Lee, H.1    Kim, Y.2    Choi, Y.3    Choi, S.4    Hong, E.5    Oh, E.-S.6
  • 22
    • 84914677725 scopus 로고    scopus 로고
    • Overexpression of syntenin enhances hepatoma cell proliferation and invasion: potential roles in human hepatoma
    • Liu, X., Zhang, X., Lv, Y., Xiang, J., and Shi, J. (2014). Overexpression of syntenin enhances hepatoma cell proliferation and invasion: potential roles in human hepatoma. Oncol. Rep. 32, 2810-2816. doi: 10.3892/or.2014.3498
    • (2014) Oncol. Rep. , vol.32 , pp. 2810-2816
    • Liu, X.1    Zhang, X.2    Lv, Y.3    Xiang, J.4    Shi, J.5
  • 23
    • 44949220276 scopus 로고    scopus 로고
    • The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling
    • Luyten, A., Mortier, E., Van Campenhout, C., Taelman, V., Degeest, G., Wuytens, G., et al. (2008). The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling. Mol. Biol. Cell 19, 1594-1604. doi: 10.1091/mbc. E07-08-0832
    • (2008) Mol. Biol. Cell , vol.19 , pp. 1594-1604
    • Luyten, A.1    Mortier, E.2    Van Campenhout, C.3    Taelman, V.4    Degeest, G.5    Wuytens, G.6
  • 24
    • 84949660806 scopus 로고    scopus 로고
    • MDA-9/Syntenin regulates differentiation and angiogenesis programs in head and neck squamous cell carcinoma
    • Oyesanya, R. A., Bhatia, S., Menezes, M. E., Dumur, C. I., Singh, K. P., Bae, S., et al. (2014). MDA-9/Syntenin regulates differentiation and angiogenesis programs in head and neck squamous cell carcinoma. Oncoscience 1, 725-737. doi: 10.18632/oncoscience.99
    • (2014) Oncoscience , vol.1 , pp. 725-737
    • Oyesanya, R.A.1    Bhatia, S.2    Menezes, M.E.3    Dumur, C.I.4    Singh, K.P.5    Bae, S.6
  • 25
    • 84875300594 scopus 로고    scopus 로고
    • Syndecan binding protein (SDCBP) is overexpressed in estrogen receptor negative breast cancers, and is a potential promoter for tumor proliferation.
    • Qian, X.-L., Li, Y.-Q., Yu, B., Gu, F., Liu, F.-F., Li, W.-D., et al. (2013). Syndecan binding protein (SDCBP) is overexpressed in estrogen receptor negative breast cancers, and is a potential promoter for tumor proliferation. PLoS ONE 8:e60046. doi: 10.1371/journal.pone.0060046
    • (2013) PLoS ONE , vol.8
    • Qian, X.-L.1    Li, Y.-Q.2    Yu, B.3    Gu, F.4    Liu, F.-F.5    Li, W.-D.6
  • 26
    • 84926524813 scopus 로고    scopus 로고
    • Heparanase activates the syndecan-syntenin-ALIX exosome pathway
    • Roucourt, B., Meeussen, S., Bao, J., Zimmermann, P., and David, G. (2015). Heparanase activates the syndecan-syntenin-ALIX exosome pathway. Cell Res. 25, 412-428. doi: 10.1038/cr.2015.29
    • (2015) Cell Res. , vol.25 , pp. 412-428
    • Roucourt, B.1    Meeussen, S.2    Bao, J.3    Zimmermann, P.4    David, G.5
  • 27
    • 0028171292 scopus 로고
    • G1 phase progression: cycling on cue
    • Sherr, C. J. (1994). G1 phase progression: cycling on cue. Cell 79, 551-555. doi: 10.1016/0092-8674(94)90540-1
    • (1994) Cell , vol.79 , pp. 551-555
    • Sherr, C.J.1
  • 28
    • 84926407723 scopus 로고    scopus 로고
    • Increased production of intestinal immunoglobulins in Syntenin-1-deficient mice
    • Tamura, K., Ikutani, M., Yoshida, T., Tanaka-Hayashi, A., Yanagibashi, T., Inoue, R., et al. (2015). Increased production of intestinal immunoglobulins in Syntenin-1-deficient mice. Immunobiology 220, 597-604. doi: 10.1016/j.imbio.2014.12.003
    • (2015) Immunobiology , vol.220 , pp. 597-604
    • Tamura, K.1    Ikutani, M.2    Yoshida, T.3    Tanaka-Hayashi, A.4    Yanagibashi, T.5    Inoue, R.6
  • 29
    • 84879075309 scopus 로고    scopus 로고
    • Elevated expression of syntenin in breast cancer is correlated with lymph node metastasis and poor patient survival.
    • Yang, Y., Hong, Q., Shi, P., Liu, Z., Luo, J., and Shao, Z. (2013). Elevated expression of syntenin in breast cancer is correlated with lymph node metastasis and poor patient survival. Breast Cancer Res. 15:R50. doi: 10.1186/bcr3442
    • (2013) Breast Cancer Res , vol.15 , pp. R50
    • Yang, Y.1    Hong, Q.2    Shi, P.3    Liu, Z.4    Luo, J.5    Shao, Z.6
  • 30
    • 0035157574 scopus 로고    scopus 로고
    • Characterization of syntenin, a syndecan-binding PDZ protein, as a component of cell adhesion sites and microfilaments
    • Zimmermann, P., Tomatis, D., Rosas, M., Grootjans, J., Leenaerts, I., Degeest, G., et al. (2001). Characterization of syntenin, a syndecan-binding PDZ protein, as a component of cell adhesion sites and microfilaments. Mol. Biol. Cell 12, 339-350. doi: 10.1091/mbc.12.2.339
    • (2001) Mol. Biol. Cell , vol.12 , pp. 339-350
    • Zimmermann, P.1    Tomatis, D.2    Rosas, M.3    Grootjans, J.4    Leenaerts, I.5    Degeest, G.6
  • 31
    • 24144482654 scopus 로고    scopus 로고
    • Syndecan recycling [corrected] is controlled by syntenin-PIP2 interaction and Arf6
    • Zimmermann, P., Zhang, Z., Degeest, G., Mortier, E., Leenaerts, I., Coomans, C., et al. (2005). Syndecan recycling [corrected] is controlled by syntenin-PIP2 interaction and Arf6. Dev. Cell 9, 377-388. doi: 10.1016/j.devcel.2005.07.011
    • (2005) Dev. Cell , vol.9 , pp. 377-388
    • Zimmermann, P.1    Zhang, Z.2    Degeest, G.3    Mortier, E.4    Leenaerts, I.5    Coomans, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.