-
1
-
-
84874377202
-
Extracellular vesicles: Exosomes, microvesicles, and friends
-
Raposo G, Stoorvogel W. Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol 2013; 200:373-383.
-
(2013)
J Cell Biol
, vol.200
, pp. 373-383
-
-
Raposo, G.1
Stoorvogel, W.2
-
2
-
-
34249302620
-
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
-
Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol 2007; 9:654-659.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 654-659
-
-
Valadi, H.1
Ekstrom, K.2
Bossios, A.3
Sjostrand, M.4
Lee, J.J.5
Lotvall, J.O.6
-
3
-
-
57049103401
-
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
-
Skog J, Wurdinger T, van Rijn S, et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol 2008; 10:1470-1476.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1470-1476
-
-
Skog, J.1
Wurdinger, T.2
Van Rijn, S.3
-
4
-
-
0029989258
-
B lymphocytes secrete antigen-presenting vesicles
-
Raposo G, Nijman HW, Stoorvogel W, et al. B lymphocytes secrete antigen-presenting vesicles. J Exp Med 1996; 183:1161-1172.
-
(1996)
J Exp Med
, vol.183
, pp. 1161-1172
-
-
Raposo, G.1
Nijman, H.W.2
Stoorvogel, W.3
-
5
-
-
0036906477
-
Indirect activation of naive CD4+ T cells by dendritic cell-derived exosomes
-
Thery C, Duban L, Segura E, Veron P, Lantz O, Amigorena S. Indirect activation of naive CD4+ T cells by dendritic cell-derived exosomes. Nat Immunol 2002; 3:1156-1162.
-
(2002)
Nat Immunol
, vol.3
, pp. 1156-1162
-
-
Thery, C.1
Duban, L.2
Segura, E.3
Veron, P.4
Lantz, O.5
Amigorena, S.6
-
6
-
-
84862007577
-
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
-
Peinado H, Aleckovic M, Lavotshkin S, et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med 2012; 18:883-891.
-
(2012)
Nat Med
, vol.18
, pp. 883-891
-
-
Peinado, H.1
Aleckovic, M.2
Lavotshkin, S.3
-
7
-
-
84871563123
-
Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration
-
Luga V, Zhang L, Viloria-Petit AM, et al. Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration. Cell 2012; 151:1542-1556.
-
(2012)
Cell
, vol.151
, pp. 1542-1556
-
-
Luga, V.1
Zhang, L.2
Viloria-Petit, A.M.3
-
8
-
-
63649086486
-
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
-
Raiborg C, Stenmark H. The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins. Nature 2009; 458:445-452.
-
(2009)
Nature
, vol.458
, pp. 445-452
-
-
Raiborg, C.1
Stenmark, H.2
-
10
-
-
77950863406
-
Molecular mechanism of multivesicular body biogenesis by ESCRT complexes
-
Wollert T, Hurley JH. Molecular mechanism of multivesicular body biogenesis by ESCRT complexes. Nature 2010; 464:864-869.
-
(2010)
Nature
, vol.464
, pp. 864-869
-
-
Wollert, T.1
Hurley, J.H.2
-
11
-
-
77954957013
-
Membrane budding and scission by the ESCRT machinery: It's all in the neck
-
Hurley JH, Hanson PI. Membrane budding and scission by the ESCRT machinery: it's all in the neck. Nat Rev Mol Cell Biol 2010; 11:556-566.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 556-566
-
-
Hurley, J.H.1
Hanson, P.I.2
-
12
-
-
40049112564
-
Ceramide triggers budding of exosome vesicles into multivesicular endosomes
-
Trajkovic K, Hsu C, Chiantia S, et al. Ceramide triggers budding of exosome vesicles into multivesicular endosomes. Science 2008; 319:1244-1247.
-
(2008)
Science
, vol.319
, pp. 1244-1247
-
-
Trajkovic, K.1
Hsu, C.2
Chiantia, S.3
-
13
-
-
84897865127
-
Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2
-
Ghossoub R, Lembo F, Rubio A, et al. Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2. Nat Commun 2014; 5:3477.
-
(2014)
Nat Commun
, vol.5
, pp. 3477
-
-
Ghossoub, R.1
Lembo, F.2
Rubio, A.3
-
14
-
-
84863206297
-
Syndecan-syntenin-ALIX regulates the biogenesis of exosomes
-
Baietti MF, Zhang Z, Mortier E, et al. Syndecan-syntenin-ALIX regulates the biogenesis of exosomes. Nat Cell Biol 2012; 14:677-685.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 677-685
-
-
Baietti, M.F.1
Zhang, Z.2
Mortier, E.3
-
15
-
-
84863199863
-
Get on the exosome bus with ALIX
-
Hurley JH, Odorizzi G. Get on the exosome bus with ALIX. Nat Cell Biol 2012; 14:654-655.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 654-655
-
-
Hurley, J.H.1
Odorizzi, G.2
-
16
-
-
0033057962
-
Mammalian heparanase: Gene cloning, expression and function in tumor progression and metastasis
-
Vlodavsky I, Friedmann Y, Elkin M, et al. Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis. Nat Med 1999; 5:793-802.
-
(1999)
Nat Med
, vol.5
, pp. 793-802
-
-
Vlodavsky, I.1
Friedmann, Y.2
Elkin, M.3
-
17
-
-
9144268931
-
High heparanase activity in multiple myeloma is associated with elevated microvessel density
-
Kelly T, Miao HQ, Yang Y, et al. High heparanase activity in multiple myeloma is associated with elevated microvessel density. Cancer Res 2003; 63:8749-8756.
-
(2003)
Cancer Res
, vol.63
, pp. 8749-8756
-
-
Kelly, T.1
Miao, H.Q.2
Yang, Y.3
-
18
-
-
4344598247
-
Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis
-
Edovitsky E, Elkin M, Zcharia E, Peretz T, Vlodavsky I. Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis. J Natl Cancer Inst 2004; 96:1219-1230.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1219-1230
-
-
Edovitsky, E.1
Elkin, M.2
Zcharia, E.3
Peretz, T.4
Vlodavsky, I.5
-
19
-
-
33748683743
-
Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis
-
Ilan N, Elkin M, Vlodavsky I. Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis. Int J Biochem Cell Biol 2006; 38:2018-2039.
-
(2006)
Int J Biochem Cell Biol
, vol.38
, pp. 2018-2039
-
-
Ilan, N.1
Elkin, M.2
Vlodavsky, I.3
-
20
-
-
25844507098
-
Cellular uptake of mammalian heparanase precursor involves low density lipoprotein receptor-related proteins, mannose 6-phosphate receptors, and heparan sulfate proteoglycans
-
Vreys V, Delande N, Zhang Z, et al. Cellular uptake of mammalian heparanase precursor involves low density lipoprotein receptor-related proteins, mannose 6-phosphate receptors, and heparan sulfate proteoglycans. J Biol Chem 2005; 280:33141-33148.
-
(2005)
J Biol Chem
, vol.280
, pp. 33141-33148
-
-
Vreys, V.1
Delande, N.2
Zhang, Z.3
-
21
-
-
3042637381
-
Processing and activation of latent heparanase occurs in lysosomes
-
Zetser A, Levy-Adam F, Kaplan V, et al. Processing and activation of latent heparanase occurs in lysosomes. J Cell Sci 2004; 117:2249-2258.
-
(2004)
J Cell Sci
, vol.117
, pp. 2249-2258
-
-
Zetser, A.1
Levy-Adam, F.2
Kaplan, V.3
-
22
-
-
2542494203
-
Heparanase induces endothelial cell migration via protein kinase B/Akt activation
-
Gingis-Velitski S, Zetser A, Flugelman MY, Vlodavsky I, Ilan N. Heparanase induces endothelial cell migration via protein kinase B/Akt activation. J Biol Chem 2004; 279:23536-23541.
-
(2004)
J Biol Chem
, vol.279
, pp. 23536-23541
-
-
Gingis-Velitski, S.1
Zetser, A.2
Flugelman, M.Y.3
Vlodavsky, I.4
Ilan, N.5
-
23
-
-
32944479184
-
Heparanase induces vascular endothelial growth factor expression: Correlation with p38 phosphorylation levels and Src activation
-
Zetser A, Bashenko Y, Edovitsky E, Levy-Adam F, Vlodavsky I, Ilan N. Heparanase induces vascular endothelial growth factor expression: correlation with p38 phosphorylation levels and Src activation. Cancer Res 2006; 66:1455-1463.
-
(2006)
Cancer Res
, vol.66
, pp. 1455-1463
-
-
Zetser, A.1
Bashenko, Y.2
Edovitsky, E.3
Levy-Adam, F.4
Vlodavsky, I.5
Ilan, N.6
-
24
-
-
62449097111
-
Structure-function approach identifies a COOH-terminal domain that mediates heparanase signaling
-
Fux L, Feibish N, Cohen-Kaplan V, et al. Structure-function approach identifies a COOH-terminal domain that mediates heparanase signaling. Cancer Res 2009; 69:1758-1767.
-
(2009)
Cancer Res
, vol.69
, pp. 1758-1767
-
-
Fux, L.1
Feibish, N.2
Cohen-Kaplan, V.3
-
25
-
-
84875994843
-
Heparanase regulates secretion, composition, and function of tumor cell-derived exosomes
-
Thompson CA, Purushothaman A, Ramani VC, Vlodavsky I, Sanderson RD. Heparanase regulates secretion, composition, and function of tumor cell-derived exosomes. J Biol Chem 2013; 288:10093-10099.
-
(2013)
J Biol Chem
, vol.288
, pp. 10093-10099
-
-
Thompson, C.A.1
Purushothaman, A.2
Ramani, V.C.3
Vlodavsky, I.4
Sanderson, R.D.5
-
26
-
-
84886387008
-
Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity
-
Christianson HC, Svensson KJ, van Kuppevelt TH, Li JP, Belting M. Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity. Proc Natl Acad Sci USA 2013; 110:17380-17385.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 17380-17385
-
-
Christianson, H.C.1
Svensson, K.J.2
Van Kuppevelt, T.H.3
Li, J.P.4
Belting, M.5
-
28
-
-
66449123730
-
Rab7 regulates late endocytic trafficking downstream of multivesicular body biogenesis and cargo sequestration
-
Vanlandingham PA, Ceresa BP. Rab7 regulates late endocytic trafficking downstream of multivesicular body biogenesis and cargo sequestration. J Biol Chem 2009; 284:12110-12124.
-
(2009)
J Biol Chem
, vol.284
, pp. 12110-12124
-
-
Vanlandingham, P.A.1
Ceresa, B.P.2
-
29
-
-
0034941051
-
FYVE and coiledcoil domains determine the specific localisation of Hrs to early endosomes
-
Raiborg C, Bremnes B, Mehlum A, et al. FYVE and coiledcoil domains determine the specific localisation of Hrs to early endosomes. J Cell Sci 2001; 114:2255-2263.
-
(2001)
J Cell Sci
, vol.114
, pp. 2255-2263
-
-
Raiborg, C.1
Bremnes, B.2
Mehlum, A.3
-
30
-
-
84925286076
-
Processing of heparanase is mediated by syndecan-1 cytoplasmic domain and involves syntenin and alpha-actinin
-
Shteingauz A, Ilan N, Vlodavsky I. Processing of heparanase is mediated by syndecan-1 cytoplasmic domain and involves syntenin and alpha-actinin. Cell Mol Life Sci 2014; 71:4457-4470.
-
(2014)
Cell Mol Life Sci
, vol.71
, pp. 4457-4470
-
-
Shteingauz, A.1
Ilan, N.2
Vlodavsky, I.3
-
31
-
-
0035157574
-
Characterization of syntenin, a syndecan-binding PDZ protein, as a component of cell adhesion sites and microfilaments
-
Zimmermann P, Tomatis D, Rosas M, et al. Characterization of syntenin, a syndecan-binding PDZ protein, as a component of cell adhesion sites and microfilaments. Mol Biol Cell 2001; 12:339-350.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 339-350
-
-
Zimmermann, P.1
Tomatis, D.2
Rosas, M.3
-
32
-
-
0037154175
-
Tumor cell surface heparan sulfate as cryptic promoters or inhibitors of tumor growth and metastasis
-
Liu D, Shriver Z, Venkataraman G, El Shabrawi Y, Sasisekharan R. Tumor cell surface heparan sulfate as cryptic promoters or inhibitors of tumor growth and metastasis. Proc Natl Acad Sci USA 2002; 99:568-573.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 568-573
-
-
Liu, D.1
Shriver, Z.2
Venkataraman, G.3
El Shabrawi, Y.4
Sasisekharan, R.5
-
33
-
-
84879605819
-
Multi-faceted substrate specificity of heparanase
-
Peterson SB, Liu J. Multi-faceted substrate specificity of heparanase. Matrix Biol 2013; 32:223-227.
-
(2013)
Matrix Biol
, vol.32
, pp. 223-227
-
-
Peterson, S.B.1
Liu, J.2
-
34
-
-
0028070639
-
An assembly domain of the Rous sarcoma virus Gag protein required late in budding
-
Wills JW, Cameron CE, Wilson CB, Xiang Y, Bennett RP, Leis J. An assembly domain of the Rous sarcoma virus Gag protein required late in budding. J Virol 1994; 68:6605-6618.
-
(1994)
J Virol
, vol.68
, pp. 6605-6618
-
-
Wills, J.W.1
Cameron, C.E.2
Wilson, C.B.3
Xiang, Y.4
Bennett, R.P.5
Leis, J.6
-
35
-
-
0025602972
-
Molecular cloning of a phosphatidylinositol-anchored membrane heparan sulfate proteoglycan from human lung fibroblasts
-
David G, Lories V, Decock B, Marynen P, Cassiman JJ, Van den Berghe H. Molecular cloning of a phosphatidylinositol-anchored membrane heparan sulfate proteoglycan from human lung fibroblasts. J Cell Biol 1990; 111:3165-3176.
-
(1990)
J Cell Biol
, vol.111
, pp. 3165-3176
-
-
David, G.1
Lories, V.2
Decock, B.3
Marynen, P.4
Cassiman, J.J.5
Van Den Berghe, H.6
-
36
-
-
0031457554
-
Syntenin, a PDZ protein that binds syndecan cytoplasmic domains
-
Grootjans JJ, Zimmermann P, Reekmans G, et al. Syntenin, a PDZ protein that binds syndecan cytoplasmic domains. Proc Natl Acad Sci USA 1997; 94:13683-13688.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13683-13688
-
-
Grootjans, J.J.1
Zimmermann, P.2
Reekmans, G.3
-
37
-
-
0026675026
-
Molecular cloning of amphiglycan, a novel integral membrane heparan sulfate proteoglycan expressed by epithelial and fibroblastic cells
-
David G, van der Schueren B, Marynen P, Cassiman JJ, van den Berghe H. Molecular cloning of amphiglycan, a novel integral membrane heparan sulfate proteoglycan expressed by epithelial and fibroblastic cells. J Cell Biol 1992; 118:961-969.
-
(1992)
J Cell Biol
, vol.118
, pp. 961-969
-
-
David, G.1
Van Der Schueren, B.2
Marynen, P.3
Cassiman, J.J.4
Van Den Berghe, H.5
-
38
-
-
0023281245
-
Identification of a 64 kDa heparan sulphate proteoglycan core protein from human lung fibroblast plasma membranes with a monoclonal antibody
-
de Boeck H, Lories V, David G, Cassiman JJ, van den Berghe H. Identification of a 64 kDa heparan sulphate proteoglycan core protein from human lung fibroblast plasma membranes with a monoclonal antibody. Biochem J 1987; 247:765-771.
-
(1987)
Biochem J
, vol.247
, pp. 765-771
-
-
De Boeck, H.1
Lories, V.2
David, G.3
Cassiman, J.J.4
Van Den Berghe, H.5
-
39
-
-
0024580166
-
Multiple distinct membrane heparan sulfate proteoglycans in human lung fibroblasts
-
Lories V, Cassiman JJ, Van den Berghe H, David G. Multiple distinct membrane heparan sulfate proteoglycans in human lung fibroblasts. J Biol Chem 1989; 264:7009-7016.
-
(1989)
J Biol Chem
, vol.264
, pp. 7009-7016
-
-
Lories, V.1
Cassiman, J.J.2
Van Den Berghe, H.3
David, G.4
-
40
-
-
0036289460
-
PIP(2)-PDZ domain binding controls the association of syntenin with the plasma membrane
-
Zimmermann P, Meerschaert K, Reekmans G, et al. PIP(2)-PDZ domain binding controls the association of syntenin with the plasma membrane. Mol Cell 2002; 9:1215-1225.
-
(2002)
Mol Cell
, vol.9
, pp. 1215-1225
-
-
Zimmermann, P.1
Meerschaert, K.2
Reekmans, G.3
|