Pathogen distribution and drug resistance in a burn ward: A three-year retrospective analysis of a single center in China

International Journal of Clinical and Experimental Medicine

Volumn 8, Issue 10, 2015, Pages 19188-19199

  Cen, Hanghui ^a   Wu, Zhenbo ^b   Wang, Fan ^a   Han, Chunmao ^a  

^a THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Bacterial; Burns; Drug resistance; Fungal; Wound infection

Indexed keywords

AMIKACIN; AMPHOTERICIN B; AMPICILLIN; AZTREONAM; CEFEPIME; CEFOPERAZONE PLUS SULBACTAM; CEFOTAXIME; CEFTAZIDIME; CEFTRIAXONE; CEFUROXIME; CIPROFLOXACIN; CLINDAMYCIN; ERTAPENEM; ERYTHROMYCIN; FLUCONAZOLE; GENTAMICIN; IMIPENEM; ITRACONAZOLE; KETOCONAZOLE; LEVOFLOXACIN; LINEZOLID; MEROPENEM; METICILLIN; OXACILLIN; PIPERACILLIN PLUS TAZOBACTAM; SULTAMICILLIN; TOBRAMYCIN; UNINDEXED DRUG; VANCOMYCIN; VORICONAZOLE;

ACINETOBACTER BAUMANNII; ADOLESCENT; ADULT; AGED; ANTIBIOTIC RESISTANCE; ARTICLE; BURN INFECTION; CANDIDA ALBICANS; CANDIDA GLABRATA; CANDIDA PARAPSILOSIS; CANDIDA TROPICALIS; CHILD; CHINA; DECISION MAKING; DISK DIFFUSION; ENTEROBACTER CLOACAE; ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM; ESCHERICHIA COLI; FEMALE; HOSPITAL INFECTION; HUMAN; INFECTION CONTROL; KLEBSIELLA PNEUMONIAE; MAJOR CLINICAL STUDY; MALE; MICROORGANISM DETECTION; PROTEUS MIRABILIS; PSEUDOMONAS AERUGINOSA; RETROSPECTIVE STUDY; SPECIES IDENTIFICATION; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS HAEMOLYTICUS; STENOTROPHOMONAS MALTOPHILIA;

EID: 84949646358     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Wang Y, Tang HT, Xia ZF, Zhu SH, Ma B, Wei W, Sun Y and Lv KY. Factors affecting survival in adult patients with massive burns. Burns 2010; 36: 57-64.
2. Ansermino M and Hemsley C. Intensive care management and control of infection. BMJ 2004; 329: 220-223.
3. Guggenheim M, Zbinden R, Handschin AE, Gohritz A, Altintas MA and Giovanoli P. Chang-es in bacterial isolates from burn wounds and their antibiograms: a 20-year study (1986-2005). Burns 2009; 35: 553-560.
4. Hodle AE, Richter KP and Thompson RM. Infection control practices in U.S. burn units. J Burn Care Res 2006; 27: 142-151.
5. Santucci SG, Gobara S, Santos CR, Fontana C and Levin AS. Infections in a burn intensive care unit: experience of seven years. J Hosp Infect 2003; 53: 6-13.
6. Giske CG, Monnet DL, Cars O and Carmeli Y. Clinical and economic impact of common multidrug-resistant gram-negative bacilli. Antimi-crob Agents Chemother 2008; 52: 813-821.
7. Manson WL, Pernot PC, Fidler V, Sauer EW and Klasen HJ. Colonization of burns and the duration of hospital stay of severely burned patients. J Hosp Infect 1992; 22: 55-63.
8. Vindenes H and Bjerknes R. Microbial colonization of large wounds. Burns 1995; 21: 575-579.
9. Sharma BR. Infection in patients with severe burns: causes and prevention thereof. Infect Dis Clin North Am 2007; 21: 745-759, ix.
10. Magnotti LJ and Deitch EA. Burns, bacterial translocation, gut barrier function, and failure. J Burn Care Rehabil 2005; 26: 383-391.
11. Soares de Macedo JL and Santos JB. Noso-comial infections in a Brazilian Burn Unit. Burns 2006; 32: 477-481.
12. Ahuja RB, Gupta A and Gur R. A prospective double-blinded comparative analysis of framycetin and silver sulphadiazine as topical agents for burns: a pilot study. Burns 2009; 35: 672-676.
13. Vindenes HA, Ulvestad E and Bjerknes R. Concentrations of cytokines in plasma of patients with large burns: their relation to time after injury, burn size, inflammatory variables, infection, and outcome. Eur J Surg 1998; 164: 647-656.
14. Alexander M, Chaudry IH and Schwacha MG. Relationships between burn size, immunosuppression, and macrophage hyperactivity in a murine model of thermal injury. Cell Immunol 2002; 220: 63-69.
15. Church D, Elsayed S, Reid O, Winston B and Lindsay R. Burn wound infections. Clin Micro-biol Rev 2006; 19: 403-434.
16. Oncul O, Ulkur E, Acar A, Turhan V, Yeniz E, Karacaer Z and Yildiz F. Prospective analysis of nosocomial infections in a burn care unit, Turkey. Indian J Med Res 2009; 130: 758-764.
17. Kumar A, Kashyap B, Mishra S, Agarwal V and Kaur IR. Bacteriological analysis and antibacterial resistance pattern in burn sepsis: An observation at a tertiary care hospital in east Delhi. Infect Dis Clin Pract 2011; 19: 406-412.
18. Mayhall CG. The epidemiology of burn wound infections: then and now. Clin Infect Dis 2003; 37: 543-550.
19. Rastegar Lari AR, Alaghehbandan R and Akhlaghi L. Burn wound infections and antimicrobial resistance in tehran, iran: an increasing problem. Ann Burns Fire Disasters 2005; 18: 68-73.
20. Avni T, Levcovich A, Ad-El DD, Leibovici L and Paul M. Prophylactic antibiotics for burns patients: systematic review and meta-analysis. BMJ 2010; 340: c241.
21. Shelby J and Merrell SW. In vivo monitoring of postburn immune response. J Trauma 1987; 27: 213-216.
22. Singh D, Singh A, Sharma AK and Sodhi L. Burn mortality in Chandigarh zone: 25 years autopsy experience from a tertiary care hospital of India. Burns 1998; 24: 150-156.
23. Sharma BR, Harish D, Singh VP and Bangar S. Septicemia as a cause of death in burns: an autopsy study. Burns 2006; 32: 545-549.
24. Taneja N, Emmanuel R, Chari P and Sharma M. A prospective study of hospital-acquired infections in burn patients at a tertiary care referral centre in North India. Burns 2004; 30: 665-669.
25. Azimi L, Motevallian A, Ebrahimzadeh Namvar A, Asghari B and Lari AR. Nosocomial infections in burned patients in motahari hospital, tehran, iran. Dermatol Res Pract 2011; 2011: 436952.
26. Özkurt Z, Altoparlak Ü, Yilmaz SI, Erol S, Özden K and Akçay MN. Reducing hospital infect-ion rates in the burn unit by adherence to infection control measures: a six-year experience. Turkish Journal of Medical Sciences 2012; 42: 17-24.
27. Bayat A, Shaaban H, Dodgson A and Dunn KW. Implications for Burns Unit design following outbreak of multi-resistant Acinetobacter infection in ICU and Burns Unit. Burns 2003; 29: 303-306.
28. Shi MM, Zhao DM, Wang Q, Cheng J, Ma T, Xu YH, Xu QL and Li JB. [Analysis of drug resistance and risk factors of Enterobacteriaceae in burn units]. Zhonghua Shao Shang Za Zhi 2010; 26: 199-201.
29. Zorgani A, Franka RA, Zaidi MM, Alshweref UM and Elgmati M. Trends in nosocomial bloodstream infections in a burn intensive care unit: an eight-year survey. Ann Burns Fire Disasters 2010; 23: 88-94.
30. Li C, Ren N, Wen X, Zhou P, Huang X, Gong R, Lv Y, Feng L, Wu H, Liu Z, Fu C, Huang X, Li J, Chen Y, Zeng C, Zuo S, Xiong X, Xu X and Wu A. Changes in antimicrobial use prevalence in China: results from five point prevalence studies. PLoS One 2013; 8: e82785.
31. Tao XB, Qian LH, Li Y, Wu Q, Ruan JJ, Cai DZ and Peng H. Hospital-acquired infection rate in a tertiary care teaching hospital in China: a cross-sectional survey involving 2434 inpatients. Int J Infect Dis 2014; 27: 7-9.
32. Peng Y and Yuan Z. Diagnostic Criteria for Infection after Burn Injury. Zhonghua Shao Shang Za Zhi 2007; 23: 404-405.
33. Li M, Zhang GA and Liu Y. [Analysis of predominant bacteria of burn infection and their resistance to antibiotics in recent years]. Zhonghua Shao Shang Za Zhi 2007; 23: 91-93.
34. Karimi H, Montevalian A, Motabar AR, Safari R, Parvas MS and Vasigh M. Epidemiology of paediatric burns in Iran. Ann Burns Fire Disasters 2012; 25: 115-120.
35. Ma JH, Peng ZY, Xu ZJ and Zhang R. Analysis of the activity of 13 antibiotics against Coryne-bacterium striatum in vitro. Laboratory Medi-cine 2007; 22: 383-384.
36. Tarr PE, Stock F, Cooke RH, Fedorko DP and Lucey DR. Multidrug-resistant Corynebacterium striatum pneumonia in a heart transplant recipient. Transpl Infect Dis 2003; 5: 53-58.
37. Sierra JM, Martinez-Martinez L, Vazquez F, Giralt E and Vila J. Relationship between mutations in the gyrA gene and quinolone resistance in clinical isolates of Corynebacterium striatum and Corynebacterium amycolatum. Antimicrob Agents Chemother 2005; 49: 1714-1719.
38. Chim H, Tan BH and Song C. Five-year review of infections in a burn intensive care unit: High incidence of Acinetobacter baumannii in a tropical climate. Burns 2007; 33: 1008-1014.
39. Peng DZ, Liu XL, Liu ZY, Shu WT, Zhou X, Liu J, Huang YS, Wu J and Fu WL. [Analysis of distribution characteristics and drug resistance of 2748 strains of pathogens isolated from burn patients]. Zhonghua Shao Shang Za Zhi 2012; 28: 87-95.
40. Keen EF III, Robinson BJ, Hospenthal DR, Aldous WK, Wolf SE, Chung KK and Murray CK. Incidence and bacteriology of burn infections at a military burn center. Burns 2010; 36: 461-468.
41. Sun FJ, Zhang XB, Fang Y, Chen J, Xing H, Shi H, Feng W and Xia P. Spectrum and drug resistance of pathogens from patients with burns. Burns 2012; 38: 1124-1130.
42. Bayram Y, Parlak M, Aypak C and Bayram I. Three-year review of bacteriological profile and antibiogram of burn wound isolates in Van, Turkey. Int J Med Sci 2013; 10: 19-23.
43. Becker K, Heilmann C and Peters G. Coagulase-negative staphylococci. Clin Microbiol Rev 2014; 27: 870-926.
44. Mirone V and Franco M. Clinical aspects of antimicrobial prophylaxis for invasive urological procedures. J Chemother 2014; 26 Suppl 1: S1-S13.
45. Aloush V, Navon-Venezia S, Seigman-Igra Y, Cabili S and Carmeli Y. Multidrug-resistant Pseudomonas aeruginosa: risk factors and clinical impact. Antimicrob Agents Chemother 2006; 50: 43-48.
46. Armour AD, Shankowsky HA, Swanson T, Lee J and Tredget EE. The impact of nosocomially-acquired resistant Pseudomonas aeruginosa infection in a burn unit. J Trauma 2007; 63: 164-171.
47. Suber F, Carroll MC and Moore FD Jr. Innate response to self-antigen significantly exacerbates burn wound depth. Proc Natl Acad Sci U S A 2007; 104: 3973-3977.
48. Rezaei E, Safari H, Naderinasab M and Aliakbarian H. Common pathogens in burn wound and changes in their drug sensitivity. Burns 2011; 37: 805-807.
49. Leseva M, Arguirova M, Nashev D, Zamfirova E and Hadzhyiski O. Nosocomial infections in burn patients: etiology, antimicrobial re-sistance, means to control. Ann Burns Fire Disasters 2013; 26: 5-11.
50. Timurkaynak F, Arslan H, Azap OK, Senger SS, Basaran O, Karaman SO and Haberal M. In vitro activity of tigecycline against resistant micro-organisms isolated from burn patients. Burns 2008; 34: 1033-1036.
51. Fadeyibi IO, Raji MA, Ibrahim NA, Ugburo AO and Ademiluyi S. Bacteriology of infected burn wounds in the burn wards of a teaching hospital in Southwest Nigeria. Burns 2013; 39: 168-173.
52. Ubbink DT, Santema TB and Stoekenbroek RM. Systemic wound care: a meta-review of cochrane systematic reviews. Surg Technol Int 2014; 24: 99-111.
53. Westh H, Zinn CS and Rosdahl VT. An international multicenter study of antimicrobial consumption and resistance in Staphylococcus aureus isolates from 15 hospitals in 14 countries. Microb Drug Resist 2004; 10: 169-176.