Characterization of Somatic Mutations in Air Pollution-Related Lung Cancer

EBioMedicine

Volumn 2, Issue 6, 2015, Pages 583-590

  Yu, Xian Jun ^a,k   Yang, Min Jun ^b   Zhou, Bo ^a   Wang, Gui Zhen ^a   Huang, Yun Chao ^c   Wu, Li Chuan ^a   Cheng, Xin ^a   Wen, Zhe Sheng ^d   Huang, Jin Yan ^e   Zhang, Yun Dong ^f   Gao, Xiao Hong ^a   Li, Gao Feng ^c   He, Shui Wang ^f,k   Gu, Zhao Hui ^e   Ma, Liang ^a   Pan, Chun Ming ^e   Wang, Ping ^g   Chen, Hao Bin ^h   Hong, Zhi Peng ⁱ   Wang, Xiao Lu ^a   Mao, Wen Jing ^a,k   Jin, Xiao Long ^e   Kang, Hui ^b   Chen, Shu Ting ^b   Zhu, Yong Qiang ^b   Gu, Wen Yi ^b   Liu, Zi ^a   Dong, Hui ^b   Tian, Lin Wei ^j   Chen, Sai Juan ^e   Cao, Yi ^f   Wang, Sheng Yue ^b   Zhou, Guang Biao ^a   more..

^a INSTITUTE OF ZOOLOGY   (China)

^b CHINESE NATIONAL HUMAN GENOME CENTER AT SHANGHAI   (China)

^c Cancer Hospital of Yunnan Province   (China)

^d SUN YAT SEN UNIVERSITY   (China)

^e SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^f KUNMING INSTITUTE OF ZOOLOGY   (China)

^g First People's Hospital of Yunnan Province   (China)

^h Department of Dermatology   (China)

ⁱ KUNMING MEDICAL UNIVERSITY   (China)

^j UNIVERSITY OF HONG KONG   (Hong Kong)

^k UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

more..

Author keywords

Air pollution; Exome sequencing; Exposure; Lung cancer; Whole genome sequencing

Indexed keywords

ABELSON TYROSINE PROTEIN KINASE 2; ANK 2 PROTEIN; BENZO[A]PYRENE; BRCA2 PROTEIN; CACNA1E PROTEIN; CACNA1S PROTEIN; CACNA2D1 PROTEIN; CASPASE 3; CSMD3 PROTEIN; CYTOCHROME P450 1A1; EPIDERMAL GROWTH FACTOR RECEPTOR; ERCC5 PROTEIN; FIBROBLAST GROWTH FACTOR 2; HISTONE LYSINE METHYLTRANSFERASE; INTERLEUKIN 6 RECEPTOR; K RAS PROTEIN; MUC 16 PROTEIN; MYH3 PROTEIN; PROTEIN; PROTEIN MCL 1; PROTEIN P53; RETINOBLASTOMA BINDING PROTEIN 1; RYANODINE RECEPTOR 1; RYANODINE RECEPTOR 2; RYANODINE RECEPTOR 3; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TTN PROTEIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; XIRP 2 PROTEIN; ZNF 831 PROTEIN; AIR POLLUTANT; COAL; SMOKE;

ADULT; AGED; AIR POLLUTION; ARTICLE; CALCIUM SIGNALING; CHROMOSOME REARRANGEMENT; CONTROLLED STUDY; COPY NUMBER VARIATION; EXOME; FEMALE; GENE MUTATION; GENE REARRANGEMENT; GENE SEQUENCE; HUMAN; LUNG ADENOCARCINOMA; MAJOR CLINICAL STUDY; MALE; NON SMALL CELL LUNG CANCER; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SOMATIC MUTATION; SQUAMOUS CELL LUNG CARCINOMA; ADVERSE EFFECTS; AIR POLLUTANT; CELL TRANSFORMATION; CHEMICALLY INDUCED; DNA SEQUENCE; ENVIRONMENTAL EXPOSURE; GENE FREQUENCY; GENETICS; GENOME; LUNG TUMOR; MIDDLE AGED; MUTATION; MUTATION RATE; NUCLEOTIDE SEQUENCE; SMOKE;

AGED; AIR POLLUTANTS; AIR POLLUTION; BASE SEQUENCE; BENZO(A)PYRENE; CARCINOMA, NON-SMALL-CELL LUNG; CELL TRANSFORMATION, NEOPLASTIC; COAL; ENVIRONMENTAL EXPOSURE; FEMALE; GENE FREQUENCY; GENOME; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUTATION; MUTATION RATE; SEQUENCE ANALYSIS, DNA; SMOKE;

EID: 84949625152     PISSN: None     EISSN: 23523964     Source Type: Journal    
DOI: 10.1016/j.ebiom.2015.04.003     Document Type: Article

References (37)

1. Anenberg S.C., Horowitz L.W., Tong D.Q., West J.J. An estimate of the global burden of anthropogenic ozone and fine particulate matter on premature human mortality using atmospheric modeling. Environ. Health Perspect. 2010, 118:1189-1195.
2. Aplan P.D. Causes of oncogenic chromosomal translocation. Trends Genet. 2006, 22:46-55.
3. Brambilla E., Travis W.D., Colby T.V., Corrin B., Shimosato Y. The new World Health Organization classification of lung tumours. Eur. Respir. J. 2001, 18:1059-1068.
4. Cao Y., Gao H. Prevalence and causes of air pollution and lung cancer in Xuanwei City and Fuyuan County, Yunnan Province, China. Front. Med. 2012, 6:217-220.
5. Chen Z. The Third Chinese National Retrospective Surveys for the Causes of Death 2008, Peking Union Medical College Press, Beijing.
6. Dearden S., Stevens J., Wu Y.L., Blowers D. Mutation incidence and coincidence in non small-cell lung cancer: meta-analyses by ethnicity and histology (mutMap). Ann. Oncol. 2013, 24:2371-2376.
7. DeMarini D.M., Landi S., Tian D., Hanley N.M., Li X., Hu F., Roop B.C., Mass M.J., Keohavong P., Gao W., Olivier M., Hainaut P., Mumford J.L. Lung tumor KRAS and TP53 mutations in nonsmokers reflect exposure to PAH-rich coal combustion emissions. Cancer Res. 2001, 61:6679-6681.
8. Eisenstadt E., Warren A.J., Porter J., Atkins D., Miller J.H. Carcinogenic epoxides of benzo[a]pyrene and cyclopenta[cd]pyrene induce base substitutions via specific transversions. Proc. Natl. Acad. Sci. 1982, 79:1945-1949.
9. Goldstraw P., Crowley J., Chansky K., Giroux D.J., Groome P.A., Rami-Porta R., Postmus P.E., Rusch V., Sobin L. The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours. J. Thorac. Oncol. 2007, 2:706-714.
10. Govindan R., Ding L., Griffith M., Subramanian J., Dees N.D., Kanchi K.L., Maher C.A., Fulton R., Fulton L., Wallis J., Chen K., Walker J., McDonald S., Bose R., Ornitz D., Xiong D., You M., Dooling D.J., Watson M., Mardis E.R., Wilson R.K. Genomic landscape of non-small cell lung cancer in smokers and never-smokers. Cell 2012, 150:1121-1134.
11. Hecht S.S. Lung carcinogenesis by tobacco smoke. Int. J. Cancer 2012, 131:2724-2732.
12. Ho A.S., Kannan K., Roy D.M., Morris L.G.T., Ganly I., Katabi N., Ramaswami D., Walsh L.A., Eng S., Huse J.T., Zhang J., Dolgalev I., Huberman K., Heguy A., Viale A., Drobnjak M., Leversha M.A., Rice C.E., Singh B., Iyer N.G., Leemans C.R., Bloemena E., Ferris R.L., Seethala R.R., Gross B.E., Liang Y., Sinha R., Peng L., Raphael B.J., Turcan S., Gong Y., Schultz N., Kim S., Chiosea S., Shah J.P., Sander C., Lee W., Chan T.A. The mutational landscape of adenoid cystic carcinoma. Nat. Genet. 2013, 45:791-798.
13. Imielinski M., Berger A.H., Hammerman P.S., Hernandez B., Pugh T.J., Hodis E., Cho J., Suh J., Capelletti M., Sivachenko A., Sougnez C., Auclair D., Lawrence M.S., Stojanov P., Cibulskis K., Choi K., de Waa L., Sharifnia T., Brooks A., Greulich H., Banerji S., Zander T., Seidel D., Leenders F., Ansén S., Ludwig C., Engel-Riedel W., Stoelbenh E., Wolf J., Goparju C., Thompson K., Winckler W., Kwiatkowski D., Johnson B.E., Jänne P.A., Miller V.A., Pao W., Travis W.D., Pass H.I., Gabriel S.B., Lander E.S., Thomas R.K., Garraway L.A., Getz G., Meyerson M. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell 2012, 150:1107-1120.
14. Irigaray P., Belpomme D. Basic properties and molecular mechanisms of exogenous chemical carcinogens. Carcinogenesis 2010, 31:135-148.
15. Kosaka T., Yatabe Y., Endoh H., Kuwano H., Takahashi T., Mitsudomi T. Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications. Cancer Res. 2004, 64:8919-8923.
16. Lan Q., Chapman R.S., Schreinemachers D.M., Tian L., He X. Household stove improvement and risk of lung cancer in Xuanwei, China. J. Natl. Cancer Inst. 2002, 94:826-835.
17. Lanner J.T., Georgiou D.K., Joshi A.D., Hamilton S.L. Ryanodine receptors: structure, expression, molecular details, and function in calcium release. Cold Spring Harb. Perspect. Biol. 2010, 2:a003996.
18. Li J.H., Zhang Y.S., Li Y., Yin G.Q., Li Y.B., Ning B.F., Guo J.M. Descriptive study on the epidemiology of lung cancer in coal-producing area in eastern Yunnan, China. Chin. J. Lung Cancer 2011, 14:107-119.
19. Loomis D., Grosse Y., Lauby-Secretan B., Ghissassi F.E., Bouvard V., Benbrhim-Tallaa L., Guha N., Baan R., Mattock H., Straif K. The carcinogenicity of outdoor air pollution. Lancet Oncol. 2013, 14:1262-1263.
20. Love C., Sun Z., Jima D., Li G., Zhang J., Miles R., Richards K.L., Dunphy C.H., Choi W.W.L., Srivastava G., Lugar P.L., Rizzieri D.A., Lagoo A.S., Bernal-Mizrachi L., Mann K.P., Flowers C.R., Naresh K.N., Evens A.M., Chadburn A., Gordon L.I., Czader M.B., Gill J.I., Hsi E.D., Greenough A., Moffitt A.B., McKinney M., Banerjee A., Grubor V., Levy S., Dunson D.B., Dave S.S. The genetic landscape of mutations in Burkitt lymphoma. Nat. Genet. 2012, 44:1321-1325.
21. Monteith G.R., Davis F.M., Roberts-Thomson S.J. Calcium channels and pumps in cancer: changes and consequences. J. Biol. Chem. 2012, 287:31666-31673.
22. Mumford J.L., He X.Z., Chapman R.S., Cao S.R., Harris D.B., Li X.M., Xian Y.L., Jiang W.Z., Xu C.W., Chuang J.C., et al. Lung cancer and indoor air pollution in Xuan Wei, China. Science 1987, 235:217-220.
23. Natrajan R., Little S.E., Reis-Filho J.S., Hing L., Messahel B., Grundy P.E., Dome J.S., Schneider T., Vujanic G.M., Pritchard-Jones K., Jones C. Amplification and overexpression of CACNA1E correlates with relapse in favorable histology Wilms' tumors. Clin. Cancer Res. 2006, 12:7284-7293.
24. Olivier M., Weninger A., Ardin M., Huskova H., Castells X., Vallee M.P., McKay J., Nedelko T., Muehlbauer K.R., Marusawa H., Alexander J., Hazelwood L., Byrnes G., Hollstein M., Zavadil J. Modelling mutational landscapes of human cancers in vitro. Sci. Rep. 2014, 4:4482.
25. Pallone T., Khurana S., Cao C. Voltage-gated calcium channels: structure and function (CACNA). Encyclopedia of Signaling Molecules 2012, 1984-1992. Springer, New York. S. Choi (Ed.).
26. Raaschou-Nielsen O., Andersen Z.J., Beelen R., Samoli E., Stafoggia M., Weinmayr G., Hoffmann B., Fischer P., Nieuwenhuijsen M., Brunekreef B., Xun W., Katsouyanni K., Dimakopoulou K., Sommar J., Forsberg B., Modig L., Oudin A., Oftedal B., Schwarze P., Per Nafstad P., De Faire F., Pedersen N.L., Ostenson C., Fratiglioni L., Penell J., Korek M., Pershagen G., Eriksen K., Sorensen M., Tjonneland A., Ellermann T., Eeftens M., Peeters P., Meliefste K., Wang M., Bueno-de-Mesquita B., Key T., de Hoogh K., Concin H., Nagel G., Vilier A., Grioni S., Krogh V., Tsai M., Ricceri F., Sacerdote C., Galassi C., Migliore E., Ranzi A., Cesaroni G., Badaloni C., Forastiere F., Tamayo I., Amiano P., Dorronsoro M., Trichopoulou A., Bamia C., Vineis P., Hoek G. Air pollution and lung cancer incidence in 17 European cohorts: prospective analyses from the European Study of Cohorts for Air Pollution Effects (ESCAPE). Lancet Oncol. 2013, 14:813-822.
27. Ruggeri B., DiRado M., Zhang S.Y., Bauer B., Goodrow T., Klein-Szanto A.J. Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene. Proc. Natl. Acad. Sci. 1993, 90:1013-1017.
28. Sinton J.E., Smith K.R., Hu H.S., Liu J.Z. Indoor Air Pollution Database for China 1995, World Health, Organization, Geneva (Switzerland), (WHO/EHG/95.8).
29. Soong T.W., Stea A., Hodson C.D., Dubel S.J., Vincent S.R., Snutch T.P. Structure and functional expression of a member of the low voltage-activated calcium channel family. Science 1993, 260:1133-1136.
30. Sullvivan J.B., Krieger G.R. Clinical Environmental Health and Toxic Exposures 2014, Lippincott Williams & Wilkins, Philadelphia, PA.
31. The Cancer Genome Atlas Research Network Comprehensive genomic characterization of squamous cell lung cancers. Nature 2012, 489:519-525.
32. van D.A., Martin R.V., Brauer M., Kahn R., Levy R., Verduzco C., Villeneuve P.J. Global estimates of ambient fine particulate matter concentrations from satellite-based aerosol optical depth: development and application. Environ. Health Perspect. 2010, 118:847-855.
33. Wang J., Mullighan C.G., Easton J., Roberts S., Heatley S.L., Ma J., Rusch M.C., Chen K., Harris C.C., Ding L., Holmfeldt L., Payne-Turner D., Fan X., Wei L., Zhao D., Obenauer J.C., Naeve C., Mardis E.R., Wilson R.K., Downing J.R., Zhang J. CREST maps somatic structural variation in cancer genomes with base-pair resolution. Nat. Methods 2011, 8:652-654.
34. World Health Organization International Agency for Research on Cancer Household use of solid fuels and high-temperature frying. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans 2010, vol. 95. (http://monographs.iarc.fr/ENG/Monographs/vol95/).
35. Xiao Y., Shao Y., Yu X., Zhou G. The epidemic status and risk factors of lung cancer in Xuanwei City, Yunnan Province, China. Front. Med. 2012, 6:388-394.
36. Zhao W., Wang L., Han H., Jin K., Lin N., Guo T., Chen Y., Cheng H., Lu F., Fang W., Wang Y., Xing B., Zhang Z. 1B50-1, a mAb raised against recurrent tumor cells, targets liver tumor-initiating cells by binding to the calcium channel alpha2delta1 subunit. Cancer Cell 2013, 23:541-556.
37. Zielinska B., Samy S., McDonald J.D., Seagrave J. Atmospheric transformation of diesel emissions. Res. Rep. Health Eff. Inst. 2010, 147:5-60.