Replication of epigenetic postpartum depression biomarkers and variation with hormone levels

Neuropsychopharmacology

Volumn 41, Issue 6, 2016, Pages 1648-1658

  Osborne, Lauren ^a   Clive, Makena ^a   Kimmel, Mary ^a   Gispen, Fiona ^a   Guintivano, Jerry ^a   Brown, Tori ^a   Cox, Olivia ^a   Judy, Jennifer ^a   Meilman, Samantha ^a   Braier, Aviva ^a   Beckmann, Matthias W ^b   Kornhuber, Johannes ^b   Fasching, Peter A ^b   Goes, Fernando ^a   Payne, Jennifer L ^a   Binder, Elisabeth B ^c   Kaminsky, Zachary ^a,d  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^c MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^d JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; ESTRADIOL; ELTANOLONE; GENETIC MARKER; HP1BP3 PROTEIN, HUMAN; NERVE PROTEIN; NUCLEAR PROTEIN; PROGESTERONE; TTC9 PROTEIN, HUMAN;

ADULT; ARTICLE; DNA METHYLATION; EPIGENETICS; FEMALE; FIRST TRIMESTER PREGNANCY; GENE; GENE EXPRESSION; HORMONE DETERMINATION; HORMONE SENSITIVITY; HP1BP3 GENE; HUMAN; MAJOR CLINICAL STUDY; MOOD DISORDER; PRIORITY JOURNAL; PROSPECTIVE STUDY; PSYCHIATRIC DIAGNOSIS; PUERPERAL DEPRESSION; SECOND TRIMESTER PREGNANCY; THIRD TRIMESTER PREGNANCY; TTC9B GENE; BLOOD; DNA MICROARRAY; GENETIC EPIGENESIS; GENETIC MARKER; GENETICS; PATHOPHYSIOLOGY; PHYSIOLOGY; PREGNANCY;

ADULT; DEPRESSION, POSTPARTUM; DNA METHYLATION; EPIGENESIS, GENETIC; ESTRADIOL; FEMALE; GENETIC MARKERS; HUMANS; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREGNANCY; PREGNANOLONE; PROGESTERONE;

EID: 84949575684     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2015.333     Document Type: Article

References (56)

1. Abbas AR, Wolslegel K, Seshasayee D, Modrusan Z, Clark HF. (2009). Deconvolution of blood microarray data identifies cellular activation patterns in systemic lupus erythematosus. PloS One 4: e6098
2. Backstrom T, Bixo M, Johansson M, Nyberg S, Ossewaarde L, Ragagnin G, et al. (2014). Allopregnanolone and mood disorders. Prog Neurobiol 113: 88-94
3. Bali A, Jaggi AS. (2014). Multifunctional aspects of allopregnanolone in stress and related disorders. Prog Neuropsychopharmacol Biol Psychiatry 48: 64-78
4. Bell AF, Carter CS, Steer CD, Golding J, Davis JM, Steffen AD, et al. (2015). Interaction between oxytocin receptor DNA methylation and genotype is associated with risk of postpartum depression in women without depression in pregnancy. Front Genet 6: 243
5. Bloch M, Schmidt PJ, Danaceau M, Murphy J, Nieman L, Rubinow DR. (2000). Effects of gonadal steroids in women with a history of postpartum depression. Am J Psychiatry 157: 924-930
6. Breese McCoy SJ. (2011). Postpartum depression: an essential overview for the practitioner. South Med J 104: 128-132
7. Bristot G, Ascoli B, Gubert C, Panizzutti B, Kapczinski F, Rosa AR. (2014). Progesterone and its metabolites as therapeutic targets in psychiatric disorders. Expert Opin Ther Target 18: 679-690
8. Cao S, Iyer JK, Lin V. (2006). Identification of tetratricopeptide repeat domain 9, a hormonally regulated protein. Biochem Biophys Res Commun 345: 310-317
9. Cuijpers P, Brannmark JG, van Straten A. (2008). Psychological treatment of postpartum depression: a meta-analysis. J Clin Psychol 64: 103-118
10. Deligiannidis KM, Sikoglu EM, Shaffer SA, Frederick B, Svenson AE, Kopoyan A, et al. (2013). GABAergic neuroactive steroids and resting-state functional connectivity in postpartum depression: a preliminary study. J Psychiatr Res 47: 816-828
11. Dutta B, Ren Y, Hao P, Sim KH, Cheow E, Adav S, et al. (2014). Profiling of the chromatin-associated proteome identifies HP1BP3 as a novel regulator of cell cycle progression. Mol Cell Proteom 13: 2183-2197
12. Eser D, Romeo E, Baghai TC, di Michele F, Schule C, Pasini A, et al. (2006). Neuroactive steroids as modulators of depression and anxiety. Neuroscience 138: 1041-1048
13. Field T. (2011). Prenatal depression effects on early development: a review. Infant Behav Dev 34: 1-14
14. Garfinkel BP, Melamed-Book N, Anuka E, Bustin M, Orly J. (2015). HP1BP3 is a novel histone H1 related protein with essential roles in viability and growth. Nucleic Acids Res 43: 2074-2090
15. Gaujoux R, Seoighe C. (2013). CellMix: a comprehensive toolbox for gene expression deconvolution. Bioinformatics 29: 2211-2212
16. Girdler SS, Lindgren M, Porcu P, Rubinow DR, Johnson JL, Morrow AL. (2012). A history of depression in women is associated with an altered GABAergic neuroactive steroid profile. Psychoneuroendocrinology 37: 543-553
17. Green AD, Galea LA. (2008). Adult hippocampal cell proliferation is suppressed with estrogen withdrawal after a hormone-simulated pregnancy. Horm Behav 54: 203-211
18. Guintivano J, Arad M, Gould TD, Payne JL, Kaminsky ZA. (2013a). Antenatal prediction of postpartum depression with blood DNA methylation biomarkers. Mol Psychiatry 19: 633
19. Guintivano J, Aryee MJ, Kaminsky ZA. (2013b). A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression. Epigenetics 8: 290-302
20. Harris B, Lovett L, Newcombe RG, Read GF, Walker R, Riad-Fahmy D. (1994). Maternity blues and major endocrine changes: Cardiff puerperal mood and hormone study II. BMJ 308: 949-953
21. Hellgren C, Akerud H, Skalkidou A, Backstrom T, Sundstrom-Poromaa I. (2014). Low serum allopregnanolone is associated with symptoms of depression in late pregnancy. Neuropsychobiology 69: 147-153
22. Hirst KP, Moutier CY. (2010). Postpartum major depression. Am Fam Physician 82: 926-933
23. Houseman EA, Accomando WP, Koestler DC, Christensen BC, Marsit CJ, Nelson HH, et al. (2012). DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics 13: 86
24. Huber W, von Heydebreck A, Sultmann H, Poustka A, Vingron M. (2002). Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics 18(Suppl 1): S96-104
25. Jernigan CS, Goswami DB, Austin MC, Iyo AH, Chandran A, Stockmeier CA, et al. (2011). The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry 35: 1774-1779
26. Ji S, Long Q, Newport DJ, Na H, Knight B, Zach EB, et al. (2011). Validity of depression rating scales during pregnancy and the postpartum period: impact of trimester and parity. J Psychiatr Res 45: 213-219
27. Josefsson A, Berg G, Nordin C, Sydsjo G. (2001). Prevalence of depressive symptoms in late pregnancy and postpartum. Acta Obstet Gynecol Scand 80: 251-255
28. Karpova NN, Lindholm JS, Kulesskaya N, Onishchenko N, Vahter M, Popova D, et al. (2014). TrkB overexpression in mice buffers against memory deficits and depression-like behavior but not all anxiety-and stress-related symptoms induced by developmental exposure to methylmercury. Front Behav Neurosci 8: 315
29. Le Melledo JM, Baker G. (2004). Role of progesterone and other neuroactive steroids in anxiety disorders. Expert Rev Neurother 4: 851-860
30. Mehta D, Newport DJ, Frishman G, Kraus L, Rex-Haffner M, Ritchie JC, et al. (2014). Early predictive biomarkers for postpartum depression point to a role for estrogen receptor signaling. Psychol Med 44: 1-14
31. Mehta D, Quast C, Fasching PA, Seifert A, Voigt F, Beckmann MW, et al. (2012). The 5-HTTLPR polymorphism modulates the influence on environmental stressors on peripartum depression symptoms. J Affect Disord 136: 1192-1197
32. Miller LJ. (2002). Postpartum depression. JAMA 287: 762-765
33. Nassa G, Tarallo R, Ambrosino C, Bamundo A, Ferraro L, Paris O, et al. (2011). A large set of estrogen receptor beta-interacting proteins identified by tandem affinity purification in hormoneresponsive human breast cancer cell nuclei. Proteomics 11: 159-165
34. O?Hara MW. (2009). Postpartum depression: what we know. J Clin Psychol 65: 1258-1269
35. Orsetti M, Di Brisco F, Canonico PL, Genazzani AA, Ghi P. (2008). Gene regulation in the frontal cortex of rats exposed to the chronic mild stress paradigm, an animal model of human depression. Eur J Neurosci 27: 2156-2164
36. Osterlund MK, Witt MR, Gustafsson JA. (2005). Estrogen action in mood and neurodegenerative disorders: estrogenic compounds with selective properties-the next generation of therapeutics. Endocrine 28: 235-242
37. Padberg F, di Michele F, Zwanzger P, Romeo E, Bernardi G, Schule C, et al. (2002). Plasma concentrations of neuroactive steroids before and after repetitive transcranial magnetic stimulation (rTMS) in major depression. Neuropsychopharmacology 27: 874-878
38. Payne JL, Palmer JT, Joffe H. (2009). A reproductive subtype of depression: conceptualizing models and moving toward etiology. Harv Rev Psychiatry 17: 72-86
39. Pearlstein T, Howard M, Salisbury A, Zlotnick C. (2009). Postpartum depression. Am J Obstet Gynecol 200: 357-364
40. Pinna G, Costa E, Guidotti A. (2006). Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptake. Psychopharmacology 186: 362-372
41. Schiller CE, Schmidt PJ, Rubinow DR. (2014). Allopregnanolone as a mediator of affective switching in reproductive mood disorders. Psychopharmacology 231: 3557-3567
42. Schule C, Nothdurfter C, Rupprecht R. (2014). The role of allopregnanolone in depression and anxiety. Prog Neurobiol 113: 79-87
43. Schumacher M, Mattern C, Ghoumari A, Oudinet JP, Liere P, Labombarda F, et al. (2014). Revisiting the roles of progesterone and allopregnanolone in the nervous system: resurgence of the progesterone receptors. Prog Neurobiol 113: 6-39
44. Shrestha S, Cao S, Lin VC. (2012). The local microenvironment instigates the regulation of mammary tetratricopeptide repeat domain 9A during lactation and involution through local regulation of the activity of estrogen receptor alpha. Biochem Biophys Rese Commun 426: 65-70
45. Shrestha S, Sun Y, Lufkin T, Kraus P, Or Y, Garcia YA, et al. (2015). Tetratricopeptide repeat domain 9A negatively regulates estrogen receptor alpha activity. Int J Biol Sci 11: 434-447
46. Soufia M, Aoun J, Gorsane MA, Krebs MO. (2010). SSRIs and pregnancy: a review of the literature. Encephale 36: 513-516
47. Strohle A, Romeo E, Hermann B, Pasini A, Spalletta G, di Michele F, et al. (1999). Concentrations of 3 alpha-reduced neuroactive steroids and their precursors in plasma of patients with major depression and after clinical recovery. Biol Psychiatry 45: 274-277
48. Suda S, Segi-Nishida E, Newton SS, Duman RS. (2008). A postpartum model in rat: behavioral and gene expression changes induced by ovarian steroid deprivation. Biol Psychiatry 64: 311-319
49. Tanaka M, Sokabe M. (2013). Bidirectional modulatory effect of 17beta-estradiol on NMDA receptors via ERalpha and ERbeta in the dentate gyrus of juvenile male rats. Neuropharmacology 75C: 262-273
50. ter Horst GJ. (2010). Estrogen in the limbic system. Vitam Horm 82: 319-338
51. Uzunova V, Sampson L, Uzunov DP. (2006). Relevance of endogenous 3alpha-reduced neurosteroids to depression and antidepressant action. Psychopharmacology 186: 351-361
52. Viguera AC, Tondo L, Koukopoulos AE, Reginaldi D, Lepri B, Baldessarini RJ. (2011). Episodes of mood disorders in 2, 252 pregnancies and postpartum periods. Am J Psychiatry 168: 1179-1185
53. Walf AA. (2010). Oestrogen receptor beta is involved in the actions of oestrogens in the brain for affective behaviour, but not trophic effects in peripheral tissues. J Neuroendocrinol 22: 141-151
54. Walf AA, Frye CA. (2005). ERbeta-selective estrogen receptor modulators produce antianxiety behavior when administered systemically to ovariectomized rats. Neuropsychopharmacology 30: 1598-1609
55. Walf AA, Koonce CJ, Frye CA. (2008). Estradiol or diarylpropionitrile decrease anxiety-like behavior of wildtype, but not estrogen receptor beta knockout, mice. Behav Neurosci 122: 974-981
56. Yoo JY, Kim TH, Lee JH, Dunwoodie SL, Ku BJ, Jeong JW. (2015). Mig-6 regulates endometrial genes involved in cell cycle and progesterone signaling. Biochem Biophys Res Commun 462: 409-414