메뉴 건너뛰기




Volumn 102, Issue 12, 2015, Pages 1053-1057

Modalities of use of ceritinib (Zykadia™), a 2nd generation ALK inhibitor, in advanced stage non-small cell lung cancer;Modalités d'utilisation du ceritinib (Zykadia™), inhibiteur de ALK de 2e génération, dans le cancer bronchique non à petites cellules de stade avancé

Author keywords

ALK rearrangement; Ceritinib; Non small cell lung cancer

Indexed keywords

CERITINIB; CRIZOTINIB; ANAPLASTIC LYMPHOMA KINASE; ANTINEOPLASTIC AGENT; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; SULFONE;

EID: 84949570924     PISSN: 00074551     EISSN: 17696917     Source Type: Journal    
DOI: 10.1016/j.bulcan.2015.09.007     Document Type: Review
Times cited : (5)

References (25)
  • 1
    • 84881230220 scopus 로고    scopus 로고
    • Biomarkers (BM) France: Results of routine EGFR, HER2, KRAS, BRAF, PI3KCA mutations detection and EML4-ALK gene fusion assessment on the first 10,000 non-small cell lung cancer (NSCLC) patients (pts)
    • abstr 8000
    • F. Barlesi, H. Blons, M. Beau-Faller, and et al. Biomarkers (BM) France: results of routine EGFR, HER2, KRAS, BRAF, PI3KCA mutations detection and EML4-ALK gene fusion assessment on the first 10,000 non-small cell lung cancer (NSCLC) patients (pts) J Clin Oncol 31 2013 abstr 8000
    • (2013) J Clin Oncol , vol.31
    • Barlesi, F.1    Blons, H.2    Beau-Faller, M.3
  • 2
    • 34547638047 scopus 로고    scopus 로고
    • Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
    • M. Soda, Y.L. Choi, M. Enomoto, and et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer Nature 448 2007 561 566
    • (2007) Nature , vol.448 , pp. 561-566
    • Soda, M.1    Choi, Y.L.2    Enomoto, M.3
  • 3
    • 70349336416 scopus 로고    scopus 로고
    • Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
    • A.T. Shaw, B.Y. Yeap, M. Mino-Kenudson, and et al. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK J Clin Oncol 27 2009 4247 4253
    • (2009) J Clin Oncol , vol.27 , pp. 4247-4253
    • Shaw, A.T.1    Yeap, B.Y.2    Mino-Kenudson, M.3
  • 4
    • 78049425319 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase inhibition in non-small cell lung cancer
    • E.L. Kwak, Y.J. Bang, D.R. Camidge, and et al. Anaplastic lymphoma kinase inhibition in non-small cell lung cancer N Engl J Med 363 2010 1693 1703
    • (2010) N Engl J Med , vol.363 , pp. 1693-1703
    • Kwak, E.L.1    Bang, Y.J.2    Camidge, D.R.3
  • 5
    • 84918804764 scopus 로고    scopus 로고
    • First-line crizotinib versus chemotherapy in ALK-positive lung cancer
    • B.J. Solomon, T. Mok, D.W. Kim, and et al. First-line crizotinib versus chemotherapy in ALK-positive lung cancer N Engl J Med 371 2014 2167 2177
    • (2014) N Engl J Med , vol.371 , pp. 2167-2177
    • Solomon, B.J.1    Mok, T.2    Kim, D.W.3
  • 6
    • 84925299472 scopus 로고    scopus 로고
    • Concomitant ALK translocation and EGFR mutation in lung cancer: A comparison of direct sequencing and sensitive assays and the impact on responsiveness to tyrosine kinase inhibitor
    • J.K. Won, B. Keam, J. Koh, and et al. Concomitant ALK translocation and EGFR mutation in lung cancer: a comparison of direct sequencing and sensitive assays and the impact on responsiveness to tyrosine kinase inhibitor Ann Oncol 26 2015 348 354
    • (2015) Ann Oncol , vol.26 , pp. 348-354
    • Won, J.K.1    Keam, B.2    Koh, J.3
  • 7
    • 84930579394 scopus 로고    scopus 로고
    • A case of crizotinib-resistant lung adenocarcinoma harboring a KRAS mutation and an EML4-ALK fusion gene
    • S. Anai, K. Suzuki, K. Ijichi, and et al. A case of crizotinib-resistant lung adenocarcinoma harboring a KRAS mutation and an EML4-ALK fusion gene J Med Cases 5 2014 631 633
    • (2014) J Med Cases , vol.5 , pp. 631-633
    • Anai, S.1    Suzuki, K.2    Ijichi, K.3
  • 8
    • 84857781304 scopus 로고    scopus 로고
    • Dual IHC and FISH testing for ALK gene rearrangement in lung adenocarcinomas in a routine practice: A French study
    • A. McLeer-Florin, D. Moro-Sibilot, A. Melis, and et al. Dual IHC and FISH testing for ALK gene rearrangement in lung adenocarcinomas in a routine practice: a French study J Thorac Oncol 7 2012 348 354
    • (2012) J Thorac Oncol , vol.7 , pp. 348-354
    • McLeer-Florin, A.1    Moro-Sibilot, D.2    Melis, A.3
  • 9
    • 84863950585 scopus 로고    scopus 로고
    • Crizotinib, modalités pratiques d'un traitement personnalisé
    • V. Fallet, C. Toper, M. Antoine, and et al. Crizotinib, modalités pratiques d'un traitement personnalisé Bull Cancer 99 2012 787 791
    • (2012) Bull Cancer , vol.99 , pp. 787-791
    • Fallet, V.1    Toper, C.2    Antoine, M.3
  • 10
    • 84856990335 scopus 로고    scopus 로고
    • Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer
    • R.C. Doebele, A.B. Pilling, D.L. Aisner, and et al. Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer Clin Cancer Res 18 2012 1472 1482
    • (2012) Clin Cancer Res , vol.18 , pp. 1472-1482
    • Doebele, R.C.1    Pilling, A.B.2    Aisner, D.L.3
  • 11
    • 84881256393 scopus 로고    scopus 로고
    • ALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: An analysis of 1,683 patients with non-small cell lung cancer
    • J.F. Gainor, A.M. Varghese, S.H. Ou, and et al. ALK rearrangements are mutually exclusive with mutations in EGFR or KRAS: an analysis of 1,683 patients with non-small cell lung cancer Clin Cancer Res 19 2013 4273 4281
    • (2013) Clin Cancer Res , vol.19 , pp. 4273-4281
    • Gainor, J.F.1    Varghese, A.M.2    Ou, S.H.3
  • 12
    • 84856999699 scopus 로고    scopus 로고
    • Mechanisms of acquired crizotinib resistance in ALK-rearranged lung cancers
    • R. Katayama, A.T. Shaw, T.M. Khan, and et al. Mechanisms of acquired crizotinib resistance in ALK-rearranged lung cancers Sci Transl Med 4 2012 120ra17
    • (2012) Sci Transl Med , vol.4 , pp. 120ra17
    • Katayama, R.1    Shaw, A.T.2    Khan, T.M.3
  • 13
    • 80052793410 scopus 로고    scopus 로고
    • A novel ALK secondary mutation and EGFR signaling cause resistance to ALK kinase inhibitors
    • T. Sasaki, J. Koivunen, A. Ogino, and et al. A novel ALK secondary mutation and EGFR signaling cause resistance to ALK kinase inhibitors Cancer Res 71 2011 6051 6060
    • (2011) Cancer Res , vol.71 , pp. 6051-6060
    • Sasaki, T.1    Koivunen, J.2    Ogino, A.3
  • 14
    • 84908363886 scopus 로고    scopus 로고
    • Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer
    • C.M. Lovly, N.T. McDonald, H. Chen, and et al. Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer Nat Med 20 2014 1027 1034
    • (2014) Nat Med , vol.20 , pp. 1027-1034
    • Lovly, C.M.1    McDonald, N.T.2    Chen, H.3
  • 15
    • 84907462932 scopus 로고    scopus 로고
    • Hypoxia induces resistance to ALK inhibitors in the H3122 non-small cell lung cancer cell line with an ALK rearrangement via epithelial-mesenchymal transition
    • A. Kogita, Y. Togashi, H. Hayashi, and et al. Hypoxia induces resistance to ALK inhibitors in the H3122 non-small cell lung cancer cell line with an ALK rearrangement via epithelial-mesenchymal transition Int J Oncol 45 2014 1430 1436
    • (2014) Int J Oncol , vol.45 , pp. 1430-1436
    • Kogita, A.1    Togashi, Y.2    Hayashi, H.3
  • 16
    • 84899887245 scopus 로고    scopus 로고
    • Induction of autophagy contributes to crizotinib resistance in ALK-positive lung cancer
    • C. Ji, L. Zhang, Y. Cheng, and et al. Induction of autophagy contributes to crizotinib resistance in ALK-positive lung cancer Cancer Biol Ther 15 2014 570 577
    • (2014) Cancer Biol Ther , vol.15 , pp. 570-577
    • Ji, C.1    Zhang, L.2    Cheng, Y.3
  • 17
    • 84880877176 scopus 로고    scopus 로고
    • Synthesis, structure-activity relationships, and in vivo efficacy of the novel potent and selective anaplastic lymphoma kinase (ALK) inhibitor 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) currently in phase 1 and phase 2 clinical trials
    • T.H. Marsilje, W. Pei, B. Chen, and et al. Synthesis, structure-activity relationships, and in vivo efficacy of the novel potent and selective anaplastic lymphoma kinase (ALK) inhibitor 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) currently in phase 1 and phase 2 clinical trials J Med Chem 56 2013 5675 5690
    • (2013) J Med Chem , vol.56 , pp. 5675-5690
    • Marsilje, T.H.1    Pei, W.2    Chen, B.3
  • 18
    • 84903466222 scopus 로고    scopus 로고
    • The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small cell lung cancer
    • L. Friboulet, N. Li, R. Katayama, and et al. The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small cell lung cancer Cancer Discov 4 2014 662 673
    • (2014) Cancer Discov , vol.4 , pp. 662-673
    • Friboulet, L.1    Li, N.2    Katayama, R.3
  • 19
    • 84896957081 scopus 로고    scopus 로고
    • Ceritinib in ALK-rearranged non-small-cell lung cancer
    • A.T. Shaw, D.W. Kim, R. Mehra, and et al. Ceritinib in ALK-rearranged non-small-cell lung cancer N Engl J Med 370 2014 1189 1197
    • (2014) N Engl J Med , vol.370 , pp. 1189-1197
    • Shaw, A.T.1    Kim, D.W.2    Mehra, R.3
  • 20
    • 84906936412 scopus 로고    scopus 로고
    • Ceritinib in advanced anaplastic lymphoma kinase (ALK+) non-small cell lung cancer (NSCLC): Results of the ASCEND-1 trial
    • abstr 8003
    • D.W. Kim, R. Mehra, D.S.W. Tan, and et al. Ceritinib in advanced anaplastic lymphoma kinase (ALK+) non-small cell lung cancer (NSCLC): results of the ASCEND-1 trial J Clin Oncol 32 2014 abstr 8003
    • (2014) J Clin Oncol , vol.32
    • Kim, D.W.1    Mehra, R.2    Tan, D.S.W.3
  • 21
    • 84941674243 scopus 로고    scopus 로고
    • ASCEND-2: A single-arm, open-label, multicenter phase II study of ceritinib in adult patients (pts) with ALK-rearranged (ALK+) non-small cell lung cancer (NSCLC) previously treated with chemotherapy and crizotinib (CRZ)
    • abstr 8059
    • T. Mok, D. Spigel, E. Felip, and et al. ASCEND-2: a single-arm, open-label, multicenter phase II study of ceritinib in adult patients (pts) with ALK-rearranged (ALK+) non-small cell lung cancer (NSCLC) previously treated with chemotherapy and crizotinib (CRZ) J Clin Oncol 33 2015 abstr 8059
    • (2015) J Clin Oncol , vol.33
    • Mok, T.1    Spigel, D.2    Felip, E.3
  • 22
    • 84938266539 scopus 로고    scopus 로고
    • Progression-free and overall survival in ALK-positive NSCLC patients treated with sequential crizotinib and ceritinib
    • J.F. Gainor, D.S. Tan, T. De Pas, and et al. Progression-free and overall survival in ALK-positive NSCLC patients treated with sequential crizotinib and ceritinib Clin Cancer Res 21 2015 2745 2752
    • (2015) Clin Cancer Res , vol.21 , pp. 2745-2752
    • Gainor, J.F.1    Tan, D.S.2    De Pas, T.3
  • 23
    • 84930609398 scopus 로고    scopus 로고
    • Identification of a novel ALK G1123S mutation in a patient with ALK-rearranged non-small-cell lung cancer exhibiting resistance to ceritinib
    • G. Toyokawa, E. Inamasu, S. Shimamatsu, and et al. Identification of a novel ALK G1123S mutation in a patient with ALK-rearranged non-small-cell lung cancer exhibiting resistance to ceritinib J Thorac Oncol 10 2015 e55 e57
    • (2015) J Thorac Oncol , vol.10 , pp. e55-e57
    • Toyokawa, G.1    Inamasu, E.2    Shimamatsu, S.3
  • 24
    • 84941413820 scopus 로고    scopus 로고
    • Survival benefit of pemetrexed in lung adenocarcinoma patients with anaplastic lymphoma kinase gene rearrangements
    • S. Park, T.S. Park, C.M. Choi, and et al. Survival benefit of pemetrexed in lung adenocarcinoma patients with anaplastic lymphoma kinase gene rearrangements Clin Lung Cancer 16 2015 e83 e89
    • (2015) Clin Lung Cancer , vol.16 , pp. e83-e89
    • Park, S.1    Park, T.S.2    Choi, C.M.3
  • 25
    • 84941637021 scopus 로고    scopus 로고
    • Efficacy and safety of the ALK inhibitor alectinib in ALK+ non-small-cell lung cancer (NSCLC) patients who have failed prior crizotinib: An open-label, single-arm, global phase 2 study (NP28673)
    • abstr 8008
    • S.H.I. Ou, J.S. Ahn, L. De Petris, and et al. Efficacy and safety of the ALK inhibitor alectinib in ALK+ non-small-cell lung cancer (NSCLC) patients who have failed prior crizotinib: an open-label, single-arm, global phase 2 study (NP28673) J Clin Oncol 33 2015 abstr 8008
    • (2015) J Clin Oncol , vol.33
    • Ou, S.H.I.1    Ahn, J.S.2    De Petris, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.