메뉴 건너뛰기




Volumn 5, Issue 9-10, 2014, Pages 303-305

Cutting the brakes and flooring the gas: How TMEPAI turns TGF-β into a tumor promoter

Author keywords

Breast cancer; TGF beta; TMEPAI

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

EID: 84949562430     PISSN: 19476019     EISSN: 19476027     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (14)
  • 1
    • 47549090432 scopus 로고    scopus 로고
    • TGFbeta in Cancer
    • Massague J: TGFbeta in Cancer. Cell 2008, 134(2):215-230.
    • (2008) Cell , vol.134 , Issue.2 , pp. 215-230
    • Massague, J.1
  • 2
    • 84894593599 scopus 로고    scopus 로고
    • Molecular mechanisms of epithelial-mesenchymal transition
    • Lamouille S, Xu J, Derynck R: Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol 2014, 15(3):178-196.
    • (2014) Nat Rev Mol Cell Biol , vol.15 , Issue.3 , pp. 178-196
    • Lamouille, S.1    Xu, J.2    Derynck, R.3
  • 5
    • 84864647706 scopus 로고    scopus 로고
    • Tgf-beta induced Erk phosphorylation of smad linker region regulates smad signaling
    • Hough C, Radu M, Dore JJ: Tgf-beta induced Erk phosphorylation of smad linker region regulates smad signaling. PLoS One 2012, 7(8):e42513.
    • (2012) Plos One , vol.7 , Issue.8
    • Hough, C.1    Radu, M.2    Dore, J.J.3
  • 6
    • 73649085521 scopus 로고    scopus 로고
    • TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling
    • Watanabe Y, Itoh S, Goto T, Ohnishi E, Inamitsu M, Itoh F, Satoh K, Wiercinska E, Yang W, Shi L et al: TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling. Mol Cell 2010, 37(1):123-134.
    • (2010) Mol Cell , vol.37 , Issue.1 , pp. 123-134
    • Watanabe, Y.1    Itoh, S.2    Goto, T.3    Ohnishi, E.4    Inamitsu, M.5    Itoh, F.6    Satoh, K.7    Wiercinska, E.8    Yang, W.9    Shi, L.10
  • 7
    • 77955401078 scopus 로고    scopus 로고
    • Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer
    • Singha PK, Yeh IT, Venkatachalam MA, Saikumar P: Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer. Cancer Res 2010, 70(15):6377-6383.
    • (2010) Cancer Res , vol.70 , Issue.15 , pp. 6377-6383
    • Singha, P.K.1    Yeh, I.T.2    Venkatachalam, M.A.3    Saikumar, P.4
  • 8
    • 78649661063 scopus 로고    scopus 로고
    • Requirement of TCF7L2 for TGF-beta-dependent transcriptional activation of the TMEPAI gene
    • Nakano N, Itoh S, Watanabe Y, Maeyama K, Itoh F, Kato M: Requirement of TCF7L2 for TGF-beta-dependent transcriptional activation of the TMEPAI gene. J Biol Chem 2010, 285(49):38023-38033.
    • (2010) J Biol Chem , vol.285 , Issue.49 , pp. 38023-38033
    • Nakano, N.1    Itoh, S.2    Watanabe, Y.3    Maeyama, K.4    Itoh, F.5    Kato, M.6
  • 9
    • 84919880342 scopus 로고    scopus 로고
    • TGF-beta induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes noncanonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer
    • Singha PK, Pandeswara S, Geng H, Lan R, Venkatachalam MA, Saikumar P: TGF-beta induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes noncanonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer. Genes & Cancer 2014.
    • (2014) Genes & Cancer
    • Singha, P.K.1    Pandeswara, S.2    Geng, H.3    Lan, R.4    Venkatachalam, M.A.5    Saikumar, P.6
  • 11
    • 79952819724 scopus 로고    scopus 로고
    • GOBO: Gene expression-based outcome for breast cancer online
    • Ringner M, Fredlund E, Hakkinen J, Borg A, Staaf J: GOBO: gene expression-based outcome for breast cancer online. PLoS One 2011, 6(3):e17911.
    • (2011) Plos One , vol.6 , Issue.3 , pp. e17911
    • Ringner, M.1    Fredlund, E.2    Hakkinen, J.3    Borg, A.4    Staaf, J.5
  • 13
    • 79959510568 scopus 로고    scopus 로고
    • When tumor suppressor TGFbeta meets the HER2 (ERBB2) oncogene
    • Chow A, Arteaga CL, Wang SE: When tumor suppressor TGFbeta meets the HER2 (ERBB2) oncogene. J Mammary Gland Biol Neoplasia 2011, 16(2):81-88.
    • (2011) J Mammary Gland Biol Neoplasia , vol.16 , Issue.2 , pp. 81-88
    • Chow, A.1    Arteaga, C.L.2    Wang, S.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.