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Volumn 7, Issue 28, 2015, Pages 2829-2833

Update on hepatitis C: Direct-acting antivirals

Author keywords

Direct acting antivirals; Hepatitis C virus; Management; Sustained virologic response; Treatment

Indexed keywords


EID: 84949561087     PISSN: None     EISSN: 19485182     Source Type: Journal    
DOI: 10.4254/wjh.v7.i28.2829     Document Type: Review
Times cited : (29)

References (44)
  • 1
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
    • [PMID: 2523562]
    • Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 1989; 244: 359-362 [PMID: 2523562 DOI: 10.1126/science.2523562]
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.L.1    Kuo, G.2    Weiner, A.J.3    Overby, L.R.4    Bradley, D.W.5    Houghton, M.6
  • 2
    • 84876149257 scopus 로고    scopus 로고
    • Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence
    • [PMID: 23172780]
    • Mohd Hanafiah K, Groeger J, Flaxman AD, Wiersma ST. Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence. Hepatology 2013; 57: 1333-1342 [PMID: 23172780 DOI: 10.1002/hep.26141]
    • (2013) Hepatology , vol.57 , pp. 1333-1342
    • Mohd Hanafiah, K.1    Groeger, J.2    Flaxman, A.D.3    Wiersma, S.T.4
  • 3
    • 79957622306 scopus 로고    scopus 로고
    • Vaccination for hepatitis C virus: closing in on an evasive target
    • [PMID: 21604986]
    • Halliday J, Klenerman P, Barnes E. Vaccination for hepatitis C virus: closing in on an evasive target. Expert Rev Vaccines 2011; 10: 659-672 [PMID: 21604986 DOI: 10.1586/erv.11.55]
    • (2011) Expert Rev Vaccines , vol.10 , pp. 659-672
    • Halliday, J.1    Klenerman, P.2    Barnes, E.3
  • 5
    • 0033406372 scopus 로고    scopus 로고
    • Hepatitis C: the clinical spectrum of the disease
    • [PMID: 10622554]
    • Marcellin P. Hepatitis C: the clinical spectrum of the disease. J Hepatol 1999; 31 Suppl 1: 9-16 [PMID: 10622554 DOI: 10.1016/S 0168-8278(99)80368-7]
    • (1999) J Hepatol , vol.31 , pp. 9-16
    • Marcellin, P.1
  • 6
    • 0035811625 scopus 로고    scopus 로고
    • Hepatitis C virus infection
    • [PMID: 11439948]
    • Lauer GM, Walker BD. Hepatitis C virus infection. N Engl J Med 2001; 345: 41-52 [PMID: 11439948 DOI: 10.1056/NEJM200107053450107]
    • (2001) N Engl J Med , vol.345 , pp. 41-52
    • Lauer, G.M.1    Walker, B.D.2
  • 7
    • 0037242882 scopus 로고    scopus 로고
    • Clinical consequences of hepatitis C virus infection
    • [PMID: 12516062]
    • Zoulim F, Chevallier M, Maynard M, Trepo C. Clinical consequences of hepatitis C virus infection. Rev Med Virol 2003; 13: 57-68 [PMID: 12516062 DOI: 10.1002/rmv.371]
    • (2003) Rev Med Virol , vol.13 , pp. 57-68
    • Zoulim, F.1    Chevallier, M.2    Maynard, M.3    Trepo, C.4
  • 10
    • 84885695869 scopus 로고    scopus 로고
    • Flaviviridae: the viruses and their replication
    • In DM Knipe and PM Howley (editors), 6th ed. Lippincott Williams&Wilkins: New York, NY
    • Lindenbach BD, Murray CL, Thiel HJ, Rice CM. Flaviviridae: the viruses and their replication. In DM Knipe and PM Howley (editors). Fields virology, 6th ed. Lippincott Williams&Wilkins: New York, NY, 2013
    • (2013) Fields virology
    • Lindenbach, B.D.1    Murray, C.L.2    Thiel, H.J.3    Rice, C.M.4
  • 11
    • 34249024924 scopus 로고    scopus 로고
    • Replication of hepatitis C virus
    • [PMID: 17487147]
    • Moradpour D, Penin F, Rice CM. Replication of hepatitis C virus. Nat Rev Microbiol 2007; 5: 453-463 [PMID: 17487147 DOI: 10.1038/nrmicro1645]
    • (2007) Nat Rev Microbiol , vol.5 , pp. 453-463
    • Moradpour, D.1    Penin, F.2    Rice, C.M.3
  • 12
    • 34548183744 scopus 로고    scopus 로고
    • Studying hepatitis C virus: making the best of a bad virus
    • [PMID: 17522203]
    • Tellinghuisen TL, Evans MJ, von Hahn T, You S, Rice CM. Studying hepatitis C virus: making the best of a bad virus. J Virol 2007; 81: 8853-8867 [PMID: 17522203 DOI: 10.1128/JVI.00753-07]
    • (2007) J Virol , vol.81 , pp. 8853-8867
    • Tellinghuisen, T.L.1    Evans, M.J.2    von Hahn, T.3    You, S.4    Rice, C.M.5
  • 13
    • 0034623816 scopus 로고    scopus 로고
    • Efficient initiation of HCV RNA replication in cell culture
    • [PMID: 11110665]
    • Blight KJ, Kolykhalov AA, Rice CM. Efficient initiation of HCV RNA replication in cell culture. Science 2000; 290: 1972-1974 [PMID: 11110665 DOI: 10.1126/science.290.5498.1972]
    • (2000) Science , vol.290 , pp. 1972-1974
    • Blight, K.J.1    Kolykhalov, A.A.2    Rice, C.M.3
  • 14
    • 0345188811 scopus 로고    scopus 로고
    • Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
    • [PMID: 10390360]
    • Lohmann V, Körner F, Koch J, Herian U, Theilmann L, Bartenschlager R. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 1999; 285: 110-113 [PMID: 10390360 DOI: 10.1126/science.285.5424.110]
    • (1999) Science , vol.285 , pp. 110-113
    • Lohmann, V.1    Körner, F.2    Koch, J.3    Herian, U.4    Theilmann, L.5    Bartenschlager, R.6
  • 15
    • 55249090938 scopus 로고    scopus 로고
    • A dynamic view of hepatitis C virus replication complexes
    • [PMID: 18715913]
    • Wölk B, Büchele B, Moradpour D, Rice CM. A dynamic view of hepatitis C virus replication complexes. J Virol 2008; 82: 10519-10531 [PMID: 18715913 DOI: 10.1128/JVI.00640-08]
    • (2008) J Virol , vol.82 , pp. 10519-10531
    • Wölk, B.1    Büchele, B.2    Moradpour, D.3    Rice, C.M.4
  • 16
    • 34247895578 scopus 로고    scopus 로고
    • The hepatitis C virus life cycle as a target for new antiviral therapies
    • [PMID: 17484890]
    • Pawlotsky JM, Chevaliez S, McHutchison JG. The hepatitis C virus life cycle as a target for new antiviral therapies. Gastroenterology 2007; 132: 1979-1998 [PMID: 17484890 DOI: 10.1053/j.gastro.2007.03.116]
    • (2007) Gastroenterology , vol.132 , pp. 1979-1998
    • Pawlotsky, J.M.1    Chevaliez, S.2    McHutchison, J.G.3
  • 18
    • 84880579978 scopus 로고    scopus 로고
    • Nucleotide prodrugs for the treatment of HCV infection
    • [PMID: 23885998]
    • Sofia MJ. Nucleotide prodrugs for the treatment of HCV infection. Adv Pharmacol 2013; 67: 39-73 [PMID: 23885998 DOI: 10.1016/B978-0-12-405880-4.00002-0]
    • (2013) Adv Pharmacol , vol.67 , pp. 39-73
    • Sofia, M.J.1
  • 19
    • 44449142885 scopus 로고    scopus 로고
    • Existence of hepatitis C virus NS5B variants naturally resistant to nonnucleoside, but not to nucleoside, polymerase inhibitors among untreated patients
    • [PMID: 18343801]
    • Le Pogam S, Seshaadri A, Kosaka A, Chiu S, Kang H, Hu S, Rajyaguru S, Symons J, Cammack N, Nájera I. Existence of hepatitis C virus NS5B variants naturally resistant to nonnucleoside, but not to nucleoside, polymerase inhibitors among untreated patients. J Antimicrob Chemother 2008; 61: 1205-1216 [PMID: 18343801 DOI: 10.1093/jac/dkn085]
    • (2008) J Antimicrob Chemother , vol.61 , pp. 1205-1216
    • Le Pogam, S.1    Seshaadri, A.2    Kosaka, A.3    Chiu, S.4    Kang, H.5    Hu, S.6    Rajyaguru, S.7    Symons, J.8    Cammack, N.9    Nájera, I.10
  • 20
  • 21
    • 84893735770 scopus 로고    scopus 로고
    • Review article: the efficacy and safety of sofosbuvir, a novel, oral nucleotide NS5B polymerase inhibitor, in the treatment of chronic hepatitis C virus infection
    • [PMID: 24387618]
    • Koff RS. Review article: the efficacy and safety of sofosbuvir, a novel, oral nucleotide NS5B polymerase inhibitor, in the treatment of chronic hepatitis C virus infection. Aliment Pharmacol Ther 2014; 39: 478-487 [PMID: 24387618 DOI: 10.1111/apt.12601]
    • (2014) Aliment Pharmacol Ther , vol.39 , pp. 478-487
    • Koff, R.S.1
  • 22
    • 33744507185 scopus 로고    scopus 로고
    • From structure to function: new insights into hepatitis C virus RNA replication
    • [PMID: 16407182]
    • Appel N, Schaller T, Penin F, Bartenschlager R. From structure to function: new insights into hepatitis C virus RNA replication. J Biol Chem 2006; 281: 9833-9836 [PMID: 16407182 DOI: 10.1074/jbc.R500026200]
    • (2006) J Biol Chem , vol.281 , pp. 9833-9836
    • Appel, N.1    Schaller, T.2    Penin, F.3    Bartenschlager, R.4
  • 23
    • 84455204716 scopus 로고    scopus 로고
    • HCV NS5A: a multifunctional regulator of cellular pathway and virus replication. In Hepatitis C Viruses
    • In: Tan SL, editor, Norfolk (UK): Horizon Bioscience, 2006: Chapter 9, [PMID: 21250384]
    • He Y, Staschke KA, Tan SL. HCV NS5A: a multifunctional regulator of cellular pathway and virus replication. In Hepatitis C Viruses. In: Tan SL, editor. SourceHepatitis C Viruses: Genomes and Molecular Biology. Norfolk (UK): Horizon Bioscience, 2006: Chapter 9 [PMID: 21250384]
    • SourceHepatitis C Viruses: Genomes and Molecular Biology
    • He, Y.1    Staschke, K.A.2    Tan, S.L.3
  • 24
    • 33644869316 scopus 로고    scopus 로고
    • Hepatitis C virus NS5A protein--a master regulator?
    • [PMID: 16530536]
    • Szabo G. Hepatitis C virus NS5A protein--a master regulator? Gastroenterology 2006; 130: 995-999 [PMID: 16530536 DOI: 10.1053/j.gastro.2006.01.072]
    • (2006) Gastroenterology , vol.130 , pp. 995-999
    • Szabo, G.1
  • 25
    • 34249664478 scopus 로고    scopus 로고
    • Phosphorylation of hepatitis C virus NS5A nonstructural protein: a new paradigm for phosphorylation-dependent viral RNA replication?
    • [PMID: 17400273]
    • Huang Y, Staschke K, De Francesco R, Tan SL. Phosphorylation of hepatitis C virus NS5A nonstructural protein: a new paradigm for phosphorylation-dependent viral RNA replication? Virology 2007; 364: 1-9 [PMID: 17400273 DOI: 10.1016/j.virol.2007.01.042]
    • (2007) Virology , vol.364 , pp. 1-9
    • Huang, Y.1    Staschke, K.2    De Francesco, R.3    Tan, S.L.4
  • 26
    • 84938552800 scopus 로고    scopus 로고
    • Effectiveness of sofosbuvir-based regimens in genotype 1 and 2 hepatitis C virus infection in 4026 U.S. Veterans
    • [PMID: 26113432]
    • Backus LI, Belperio PS, Shahoumian TA, Loomis TP, Mole LA. Effectiveness of sofosbuvir-based regimens in genotype 1 and 2 hepatitis C virus infection in 4026 U.S. Veterans. Aliment Pharmacol Ther 2015; 42: 559-573 [PMID: 26113432 DOI: 10.1111/apt.13300]
    • (2015) Aliment Pharmacol Ther , vol.42 , pp. 559-573
    • Backus, L.I.1    Belperio, P.S.2    Shahoumian, T.A.3    Loomis, T.P.4    Mole, L.A.5
  • 32
    • 84929607189 scopus 로고    scopus 로고
    • Treatment with ledipasvir and sofosbuvir improves patient-reported outcomes: Results from the ION-1, -2, and -3 clinical trials
    • [PMID: 25627448]
    • Younossi ZM, Stepanova M, Marcellin P, Afdhal N, Kowdley KV, Zeuzem S, Hunt SL. Treatment with ledipasvir and sofosbuvir improves patient-reported outcomes: Results from the ION-1, -2, and -3 clinical trials. Hepatology 2015; 61: 1798-1808 [PMID: 25627448 DOI: 10.1002/hep.27724]
    • (2015) Hepatology , vol.61 , pp. 1798-1808
    • Younossi, Z.M.1    Stepanova, M.2    Marcellin, P.3    Afdhal, N.4    Kowdley, K.V.5    Zeuzem, S.6    Hunt, S.L.7
  • 41
    • 84907525692 scopus 로고    scopus 로고
    • Sofosbuvir/ledipasvir fixed dose combination is safe and effective in difficult-to-treat populations including genotype-3 patients, decompensated genotype-1 patients, and genotype-1 patients with prior sofosbuvir treatment experience
    • Gane EJ, Hyland RH, An D, Pang PS, Symonds WT, McHutchison JG, Stedman CA. Sofosbuvir/ledipasvir fixed dose combination is safe and effective in difficult-to-treat populations including genotype-3 patients, decompensated genotype-1 patients, and genotype-1 patients with prior sofosbuvir treatment experience. J Hepatol 2014; 60: S1-S22 [DOI: 10.1016/S0168-8278(14)60008-8]
    • (2014) J Hepatol , vol.60 , pp. S1-S22
    • Gane, E.J.1    Hyland, R.H.2    An, D.3    Pang, P.S.4    Symonds, W.T.5    McHutchison, J.G.6    Stedman, C.A.7
  • 42
    • 84908086002 scopus 로고    scopus 로고
    • Sofosbuvir plus ribavirin, an interferon-free regimen, in the treatment of treatment-naive and treatment-experienced patients with chronic genotype 4 HCV infection
    • Ruane PJ, Ain D, Meshrekey R, Riad J, Stryker R, Soliman M, Mikhail S, Wolfe PR, Kersey K, Doehle B, Deyuan J, Symonds WT. Sofosbuvir plus ribavirin, an interferon-free regimen, in the treatment of treatment-naive and treatment-experienced patients with chronic genotype 4 HCV infection. J Hepatol 2014; 60: S503-S504 [DOI: 10.1016/S0168-8278(14)61403-3]
    • (2014) J Hepatol , vol.60 , pp. S503-S504
    • Ruane, P.J.1    Ain, D.2    Meshrekey, R.3    Riad, J.4    Stryker, R.5    Soliman, M.6    Mikhail, S.7    Wolfe, P.R.8    Kersey, K.9    Doehle, B.10    Deyuan, J.11    Symonds, W.T.12
  • 43
    • 84939653819 scopus 로고    scopus 로고
    • Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus
    • [PMID: 26111063]
    • AASLD/IDSA HCV Guidance Panel. Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Hepatology 2015; 62: 932-954 [PMID: 26111063 DOI: 10.1002/hep.27950]
    • (2015) Hepatology , vol.62 , pp. 932-954
  • 44
    • 84931560807 scopus 로고    scopus 로고
    • EASL Recommendations on Treatment of Hepatitis C 2015
    • [PMID: 25911336]
    • European Association for Study of Liver. EASL Recommendations on Treatment of Hepatitis C 2015. J Hepatol 2015; 63: 199-236 [PMID: 25911336 DOI: 10.1016/j.jhep.2015.03.025]
    • (2015) J Hepatol , vol.63 , pp. 199-236


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.