Erythropoietin protects the tubular basement membrane by promoting the bone marrow to release extracellular vesicles containing tPA-targeting miR-144

American Journal of Physiology - Renal Physiology

Volumn 310, Issue 1, 2015, Pages F27-F40

  Zhou, Yang ^a   Fang, Li ^a   Yu, Yanting ^a   Niu, Jing ^a   Jiang, Lei ^a   Cao, Hongdi ^a   Sun, Qi ^a   Zen, Ke ^a,b   Dai, Chunsun ^a   Yang, Junwei ^a  

^a THE SECOND AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

EPO; Extracellular vesicle; MiRNA; Renal fibrosis; Tubular basement membrane

Indexed keywords

CD11B ANTIGEN; CD19 ANTIGEN; GELATINASE B; HERMES ANTIGEN; KIDNEY PROTECTIVE AGENT; LAMININ; MICRORNA; MICRORNA 144; PROTECTIVE AGENT; RECOMBINANT ERYTHROPOIETIN; STEM CELL ANTIGEN 1; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; EPO PROTEIN, HUMAN; ERYTHROPOIETIN; MIRN144 MICRORNA, HUMAN; MIRN144 MICRORNA, MOUSE; MIRN144 MICRORNA, RAT; MMP9 PROTEIN, MOUSE; RECOMBINANT PROTEIN;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATROPHY; BINDING SITE; BONE MARROW CELL; CELL DAMAGE; CELL STIMULATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REPRESSION; EXOSOME; EXPERIMENTAL RENAL FIBROSIS; FIBROBLAST; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; KIDNEY STRUCTURE; KIDNEY TUBULE BASEMENT MEMBRANE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; RENAL PROTECTION; RNA SYNTHESIS; UPREGULATION; ANIMAL; BLOOD; CELL LINE; CELL PROTECTION; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; FIBROSIS; GENETICS; GLOMERULUS BASEMENT MEMBRANE; KIDNEY DISEASES; KIDNEY TUBULE; METABOLISM; PATHOLOGY; RAT; SIGNAL TRANSDUCTION; URETERAL OBSTRUCTION;

3' UNTRANSLATED REGIONS; ANIMALS; BINDING SITES; BONE MARROW CELLS; CELL LINE; CYTOPROTECTION; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; ENZYME REPRESSION; ERYTHROPOIETIN; EXTRACELLULAR VESICLES; FIBROBLASTS; FIBROSIS; GLOMERULAR BASEMENT MEMBRANE; KIDNEY DISEASES; KIDNEY TUBULES; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICRORNAS; RATS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TISSUE PLASMINOGEN ACTIVATOR; URETERAL OBSTRUCTION;

EID: 84949558595     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00303.2015     Document Type: Article

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