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Volumn 32, Issue 12, 2015, Pages 944-957

INFLUENCE of STUDY DESIGN on TREATMENT RESPONSE in ANXIETY DISORDER CLINICAL TRIALS

Author keywords

antidepressants; anxiety anxiety disorder; clinical trials; pharmacotherapy; treatment

Indexed keywords

ATENOLOL; BUSPIRONE; CITALOPRAM; CLOMIPRAMINE; DESIPRAMINE; DULOXETINE; ESCITALOPRAM; FLUOXETINE; FLUVOXAMINE; HYDROXYZINE; IMIPRAMINE; MAPROTILINE; MIRTAZAPINE; MONOAMINE OXIDASE INHIBITOR; NEFAZODONE; PAROXETINE; PLACEBO; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRICYCLIC ANTIDEPRESSANT AGENT; VENLAFAXINE; VORTIOXETINE; ZIMELDINE;

EID: 84949556541     PISSN: 10914269     EISSN: 15206394     Source Type: Journal    
DOI: 10.1002/da.22433     Document Type: Article
Times cited : (16)

References (99)
  • 1
    • 0037051872 scopus 로고    scopus 로고
    • Placebo response in studies of major depression: Variable, substantial, and growing
    • Walsh BT, Seidman SN, Sysko R, Gould M,. Placebo response in studies of major depression: variable, substantial, and growing. J Am Med Assoc 2002; 287: 1840-1847.
    • (2002) J Am Med Assoc , vol.287 , pp. 1840-1847
    • Walsh, B.T.1    Seidman, S.N.2    Sysko, R.3    Gould, M.4
  • 2
    • 84915775143 scopus 로고    scopus 로고
    • Placebo response in antipsychotic clinical trials: A meta-analysis
    • Rutherford BR, Pott E, Tandler JM, et al., Placebo response in antipsychotic clinical trials: a meta-analysis. J Am Med Assoc Psychiatry 2014; 71: 1409-1421.
    • (2014) J Am Med Assoc Psychiatry , vol.71 , pp. 1409-1421
    • Rutherford, B.R.1    Pott, E.2    Tandler, J.M.3
  • 3
    • 0037266035 scopus 로고    scopus 로고
    • The problem of the placebo response in clinical trials for psychiatric disorders: Culprits, possible remedies, and a novel study design approach
    • Fava M, Evins AE, Dorer DJ, Schoenfeld DA,. The problem of the placebo response in clinical trials for psychiatric disorders: culprits, possible remedies, and a novel study design approach. Psychother Psychosom 2003; 72: 115-127.
    • (2003) Psychother Psychosom , vol.72 , pp. 115-127
    • Fava, M.1    Evins, A.E.2    Dorer, D.J.3    Schoenfeld, D.A.4
  • 4
    • 0035118638 scopus 로고    scopus 로고
    • Placebo response in depression: Bane of research, boon to therapy
    • Andrews G., Placebo response in depression: bane of research, boon to therapy. Br J Psychiatry 2001; 178: 192-194.
    • (2001) Br J Psychiatry , vol.178 , pp. 192-194
    • Andrews, G.1
  • 5
    • 84883203780 scopus 로고    scopus 로고
    • A model of placebo effects in antidepressant clinical trials
    • Rutherford BR, Roose SP,. A model of placebo effects in antidepressant clinical trials. Am J Psychiatry 2013; 170: 723-733.
    • (2013) Am J Psychiatry , vol.170 , pp. 723-733
    • Rutherford, B.R.1    Roose, S.P.2
  • 6
    • 0036237860 scopus 로고    scopus 로고
    • The functional neuroanatomy of the placebo effect
    • Mayberg HS, Silva JA, Brannan SK, et al., The functional neuroanatomy of the placebo effect. Am J Psychiatry 2002; 159: 728-737.
    • (2002) Am J Psychiatry , vol.159 , pp. 728-737
    • Mayberg, H.S.1    Silva, J.A.2    Brannan, S.K.3
  • 7
    • 0030670551 scopus 로고    scopus 로고
    • Placebo response in generalized anxiety: Its effect on the outcome of clinical trials
    • Schweizer E, Rickels K,. Placebo response in generalized anxiety: its effect on the outcome of clinical trials. J Clin Psychiatry 1997; 58 (Suppl 11): 30-38.
    • (1997) J Clin Psychiatry , vol.58 , pp. 30-38
    • Schweizer, E.1    Rickels, K.2
  • 8
    • 33845619513 scopus 로고    scopus 로고
    • Which factors predict placebo response in anxiety disorders and major depression? An analysis of placebo-controlled studies of Escitalopram
    • Stein DJ, Baldwin DS, Dolberg OT, Despiegel N, Bandelow B,. Which factors predict placebo response in anxiety disorders and major depression? An analysis of placebo-controlled studies of Escitalopram. J Clin Psychiatry 2006; 67: 1741-1746.
    • (2006) J Clin Psychiatry , vol.67 , pp. 1741-1746
    • Stein, D.J.1    Baldwin, D.S.2    Dolberg, O.T.3    Despiegel, N.4    Bandelow, B.5
  • 10
    • 19144366837 scopus 로고    scopus 로고
    • Magnitude of placebo response and drug-placebo differences across psychiatric disorders
    • Khan A, Kolts RL, Rapaport MH, et al., Magnitude of placebo response and drug-placebo differences across psychiatric disorders. Psychol Med 2005; 35: 743-749.
    • (2005) Psychol Med , vol.35 , pp. 743-749
    • Khan, A.1    Kolts, R.L.2    Rapaport, M.H.3
  • 11
    • 70349770836 scopus 로고    scopus 로고
    • Development of a patient-reported assessment to identify placebo responders in a generalized anxiety disorder trial
    • Feltner D, Hill C, Lenderking W, Williams V, Morlock R,. Development of a patient-reported assessment to identify placebo responders in a generalized anxiety disorder trial. J Psychiatr Res 2009; 43: 1224-1230.
    • (2009) J Psychiatr Res , vol.43 , pp. 1224-1230
    • Feltner, D.1    Hill, C.2    Lenderking, W.3    Williams, V.4    Morlock, R.5
  • 13
    • 77249109450 scopus 로고    scopus 로고
    • Predictors of placebo response in randomized controlled trials of psychotropic drugs for children and adolescents with internalizing disorders
    • Cohen D, Consoli A, Bodeau N, et al., Predictors of placebo response in randomized controlled trials of psychotropic drugs for children and adolescents with internalizing disorders. J Child Adolesc Psychopharmacol 2010; 20: 39-47.
    • (2010) J Child Adolesc Psychopharmacol , vol.20 , pp. 39-47
    • Cohen, D.1    Consoli, A.2    Bodeau, N.3
  • 14
    • 62849102660 scopus 로고    scopus 로고
    • Does study design affect outcome? the effects of placebo control and treatment duration in antidepressant trials
    • Rutherford BR, Sneed JR, Roose SP,. Does study design affect outcome? The effects of placebo control and treatment duration in antidepressant trials. Psychother Psychosom 2009; 78: 172-181.
    • (2009) Psychother Psychosom , vol.78 , pp. 172-181
    • Rutherford, B.R.1    Sneed, J.R.2    Roose, S.P.3
  • 18
    • 0032333396 scopus 로고    scopus 로고
    • Using odds ratios as effect sizes for meta-analysis of dichotomous data: A primer on methods and issues
    • Haddock CK, Rindskopf D, Shadish WR., Using odds ratios as effect sizes for meta-analysis of dichotomous data: a primer on methods and issues. Psychol Methods 1998; 3: 339-353.
    • (1998) Psychol Methods , vol.3 , pp. 339-353
    • Haddock, C.K.1    Rindskopf, D.2    Shadish, W.R.3
  • 20
    • 84928203132 scopus 로고    scopus 로고
    • Clinic visits in late life depression trials: Effects on signal detection and therapeutic outcome
    • Rutherford BR, Tandler J, Brown P, Sneed JR, Roose SP,. Clinic visits in late life depression trials: effects on signal detection and therapeutic outcome. Am J Geriatr Psychiatry 2014; 22: 1452-1461.
    • (2014) Am J Geriatr Psychiatry , vol.22 , pp. 1452-1461
    • Rutherford, B.R.1    Tandler, J.2    Brown, P.3    Sneed, J.R.4    Roose, S.P.5
  • 21
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins JPT, Thompson SG,. Quantifying heterogeneity in a meta-analysis. Stat Med 2002; 21: 1539-1558.
    • (2002) Stat Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.T.1    Thompson, S.G.2
  • 22
    • 0344223296 scopus 로고    scopus 로고
    • Evaluation of old and new tests of heterogeneity in epidemiologic meta-analysis
    • Takkouche B, Cadarso Surez C, Spiegelman D,. Evaluation of old and new tests of heterogeneity in epidemiologic meta-analysis. Am J Epidemiol 1999; 150: 206-215.
    • (1999) Am J Epidemiol , vol.150 , pp. 206-215
    • Takkouche, B.1    Cadarso Surez, C.2    Spiegelman, D.3
  • 23
    • 0032867886 scopus 로고    scopus 로고
    • Paroxetine in social anxiety disorder: A randomized placebo-controlled study
    • Allgulander C., Paroxetine in social anxiety disorder: a randomized placebo-controlled study. Acta Psychiatr Scand 1999; 100: 193-198.
    • (1999) Acta Psychiatr Scand , vol.100 , pp. 193-198
    • Allgulander, C.1
  • 24
    • 4444345940 scopus 로고    scopus 로고
    • Efficacy of sertraline in a 12-week trial for generalized anxiety disorder
    • Allgulander C, Dahl AA, Austin C, et al., Efficacy of sertraline in a 12-week trial for generalized anxiety disorder. Am J Psychiatry 2004; 161: 1642-1649.
    • (2004) Am J Psychiatry , vol.161 , pp. 1642-1649
    • Allgulander, C.1    Dahl, A.A.2    Austin, C.3
  • 25
    • 34347264464 scopus 로고    scopus 로고
    • Pharmacotherapy of generalized anxiety disorder: Results of duloxetine treatment from a pooled analysis of three clinical trials
    • Allgulander C, Hartford J, Russell J, et al., Pharmacotherapy of generalized anxiety disorder: results of duloxetine treatment from a pooled analysis of three clinical trials. Curr Med Res Opin 2007; 23: 1245-1252.
    • (2007) Curr Med Res Opin , vol.23 , pp. 1245-1252
    • Allgulander, C.1    Hartford, J.2    Russell, J.3
  • 26
    • 4444333450 scopus 로고    scopus 로고
    • Efficacy of venlafaxine ER in patients with social anxiety disorder: A double-blind, placebo-controlled, parallel-group comparison with paroxetine
    • Allgulander C, Mangano R, Zhang J, et al., Efficacy of venlafaxine ER in patients with social anxiety disorder: a double-blind, placebo-controlled, parallel-group comparison with paroxetine. Hum Psychopharmacol 2004; 19: 387-396.
    • (2004) Hum Psychopharmacol , vol.19 , pp. 387-396
    • Allgulander, C.1    Mangano, R.2    Zhang, J.3
  • 27
    • 33847038810 scopus 로고    scopus 로고
    • Flovoxamine treatment of generalized social anxiety disorder in Japan: A randomized double-blind, placebo-controlled study
    • Asakura S, Tajima O, Koyama T,. Flovoxamine treatment of generalized social anxiety disorder in Japan: a randomized double-blind, placebo-controlled study. Int J Neuropsychopharmacol 2007; 10: 263-274.
    • (2007) Int J Neuropsychopharmacol , vol.10 , pp. 263-274
    • Asakura, S.1    Tajima, O.2    Koyama, T.3
  • 28
    • 0035812174 scopus 로고    scopus 로고
    • Fluvoxamine in the treatment of panic disorder: A multi-center, double-blind, placebo-controlled study in outpatients
    • Asnis GM, Hameedi FA, Goddard AW, et al., Fluvoxamine in the treatment of panic disorder: a multi-center, double-blind, placebo-controlled study in outpatients. Psychiatry Res 2001; 103: 1-14.
    • (2001) Psychiatry Res , vol.103 , pp. 1-14
    • Asnis, G.M.1    Hameedi, F.A.2    Goddard, A.W.3
  • 29
    • 0032773913 scopus 로고    scopus 로고
    • Paroxetine in social phobia/social anxiety disorder. Randomised, double-blind, placebo-controlled study. Paroxetine study group
    • Baldwin D, Bobes J, Stein DJ, Scharwachter I, Faure M,. Paroxetine in social phobia/social anxiety disorder. Randomised, double-blind, placebo-controlled study. Paroxetine study group. Br J Psychiatry 1999; 175: 120-126.
    • (1999) Br J Psychiatry , vol.175 , pp. 120-126
    • Baldwin, D.1    Bobes, J.2    Stein, D.J.3    Scharwachter, I.4    Faure, M.5
  • 30
    • 33748432736 scopus 로고    scopus 로고
    • Escitalopram and paroxetine in the treatment of generalised anxiety disorder: Randomised, placebo-controlled, double-blind study
    • Baldwin DS, Huusom AK, Maehlum E,. Escitalopram and paroxetine in the treatment of generalised anxiety disorder: randomised, placebo-controlled, double-blind study. Br J Psychiatry 2006; 189: 264-272.
    • (2006) Br J Psychiatry , vol.189 , pp. 264-272
    • Baldwin, D.S.1    Huusom, A.K.2    Maehlum, E.3
  • 31
    • 13844306619 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitor treatment for generalized anxiety disorder: A double-blind, prospective comparison between paroxetine and sertraline
    • Ball SG, Kuhn A, Wall D, Shekhar A, Goddard AW,. Selective serotonin reuptake inhibitor treatment for generalized anxiety disorder: a double-blind, prospective comparison between paroxetine and sertraline. J Clin Psychiatry 2005; 66: 94-99.
    • (2005) J Clin Psychiatry , vol.66 , pp. 94-99
    • Ball, S.G.1    Kuhn, A.2    Wall, D.3    Shekhar, A.4    Goddard, A.W.5
  • 32
    • 0031984862 scopus 로고    scopus 로고
    • Double-blind, fixed dose, placebo-controlled study of paroxetine in the treatment of panic disorder
    • Ballenger JC, Wheadon DE, Steiner M, Bushnell W, Gergel IP,. Double-blind, fixed dose, placebo-controlled study of paroxetine in the treatment of panic disorder. Am J Psychiatry 1998; 155: 36-42.
    • (1998) Am J Psychiatry , vol.155 , pp. 36-42
    • Ballenger, J.C.1    Wheadon, D.E.2    Steiner, M.3    Bushnell, W.4    Gergel, I.P.5
  • 33
    • 2342643433 scopus 로고    scopus 로고
    • Sertraline versus paroxetine in the treatment of panic disorder: An acute, double-blind noninferiority comparison
    • Bandelow B, Behnke K, Lenoir S, et al., Sertraline versus paroxetine in the treatment of panic disorder: an acute, double-blind noninferiority comparison. J Clin Psychiatry 2004; 65: 405-413.
    • (2004) J Clin Psychiatry , vol.65 , pp. 405-413
    • Bandelow, B.1    Behnke, K.2    Lenoir, S.3
  • 34
    • 22044432722 scopus 로고    scopus 로고
    • A double-blind comparison of escitalopram and paroxetine in the long-term treatment of generalized anxiety disorder
    • Bielski RJ, Bose A, Chang CC,. A double-blind comparison of escitalopram and paroxetine in the long-term treatment of generalized anxiety disorder. Ann Clin Psychiatry 2005; 17: 65-69.
    • (2005) Ann Clin Psychiatry , vol.17 , pp. 65-69
    • Bielski, R.J.1    Bose, A.2    Chang, C.C.3
  • 35
    • 84870717545 scopus 로고    scopus 로고
    • Vortioxetine (Lu AA21004) in generalized anxiety disorder: Results of an 8-week, multinational, randomized, double-blind, placebo-controlled clinical trial
    • Bidzan L, Mahableshwarkar AR, Jacobsen P, Yan M, Sheehan DV,. Vortioxetine (Lu AA21004) in generalized anxiety disorder: results of an 8-week, multinational, randomized, double-blind, placebo-controlled clinical trial. Eur Neuropsychopharmacol 2012; 22: 847-857.
    • (2012) Eur Neuropsychopharmacol , vol.22 , pp. 847-857
    • Bidzan, L.1    Mahableshwarkar, A.R.2    Jacobsen, P.3    Yan, M.4    Sheehan, D.V.5
  • 36
    • 0023672570 scopus 로고
    • Effect of a serotonin and noradrenaline uptake inhibitor in panic disorder; A double-blind comparative study with fluvoxamine and maprotiline
    • Den Boer JA, Westenberg HG,. Effect of a serotonin and noradrenaline uptake inhibitor in panic disorder; a double-blind comparative study with fluvoxamine and maprotiline. Int Clin Psychopharmacol 1988; 3: 59-74.
    • (1988) Int Clin Psychopharmacol , vol.3 , pp. 59-74
    • Den Boer, J.A.1    Westenberg, H.G.2
  • 37
    • 55549138381 scopus 로고    scopus 로고
    • Randomized placebo-controlled trial of escitalopram and venlafaxine XR in the treatment of generalized anxiety disorder
    • Bose A, Korotzer A, Gommoll C, Li D,. Randomized placebo-controlled trial of escitalopram and venlafaxine XR in the treatment of generalized anxiety disorder. Depress Anxiety 2008; 25: 854-861.
    • (2008) Depress Anxiety , vol.25 , pp. 854-861
    • Bose, A.1    Korotzer, A.2    Gommoll, C.3    Li, D.4
  • 38
    • 26644432917 scopus 로고    scopus 로고
    • Venlafaxine extended-release capsules in panic disorder: Flexible-dose, double-blind, placebo-controlled study
    • Bradwejn J, Ahokas A, Stein DJ, et al., Venlafaxine extended-release capsules in panic disorder: flexible-dose, double-blind, placebo-controlled study. Br J Psychiatry 2005; 187: 352-359.
    • (2005) Br J Psychiatry , vol.187 , pp. 352-359
    • Bradwejn, J.1    Ahokas, A.2    Stein, D.J.3
  • 39
    • 33745877173 scopus 로고    scopus 로고
    • Sertraline treatment for generalized anxiety disorder: A randomized, double-blind, placebo-controlled study
    • Brawman-Mintzer O, Knapp RG, Rynn M, Carter RE, Rickels K,. Sertraline treatment for generalized anxiety disorder: a randomized, double-blind, placebo-controlled study. J Clin Psychiatry 2006; 67: 874-881.
    • (2006) J Clin Psychiatry , vol.67 , pp. 874-881
    • Brawman-Mintzer, O.1    Knapp, R.G.2    Rynn, M.3    Carter, R.E.4    Rickels, K.5
  • 40
    • 0032933022 scopus 로고    scopus 로고
    • Comparative effects of low and high doses of clomipramine and placebo in panic disorder: A double-blind controlled study. French University Antidepressant Group
    • Caillard V, Rouillon F, Viel JF, Markabi S,. Comparative effects of low and high doses of clomipramine and placebo in panic disorder: a double-blind controlled study. French University Antidepressant Group. Acta Psychiatr Scand 1999; 99: 51-58.
    • (1999) Acta Psychiatr Scand , vol.99 , pp. 51-58
    • Caillard, V.1    Rouillon, F.2    Viel, J.F.3    Markabi, S.4
  • 41
    • 3543042491 scopus 로고    scopus 로고
    • Escitalopram in the treatment of generalized anxiety disorder: Double-blind, placebo controlled, flexible-dose study
    • Davidson JR, Bose A, Korotzer A, Zheng H,. Escitalopram in the treatment of generalized anxiety disorder: double-blind, placebo controlled, flexible-dose study. Depress Anxiety 2004; 19: 234-240.
    • (2004) Depress Anxiety , vol.19 , pp. 234-240
    • Davidson, J.R.1    Bose, A.2    Korotzer, A.3    Zheng, H.4
  • 42
    • 1642307074 scopus 로고    scopus 로고
    • Fluvoxamine-controlled release formulation for the treatment of generalized social anxiety disorder
    • Davidson J, Yaryura-Tobias J, DuPont R, et al., Fluvoxamine-controlled release formulation for the treatment of generalized social anxiety disorder. J Clin Psychopharmacol 2004; 24: 118-125.
    • (2004) J Clin Psychopharmacol , vol.24 , pp. 118-125
    • Davidson, J.1    Yaryura-Tobias, J.2    DuPont, R.3
  • 43
    • 0022633377 scopus 로고
    • Effect of a selective serotonin uptake inhibitor in agoraphobia with panic attacks. A double-blind comparison of zimeldine, imipramine and placebo
    • Evans L, Kenardy J, Schneider P, Hoey H,. Effect of a selective serotonin uptake inhibitor in agoraphobia with panic attacks. A double-blind comparison of zimeldine, imipramine and placebo. Acta Psychiatr Scand 1986; 73: 49-53.
    • (1986) Acta Psychiatr Scand , vol.73 , pp. 49-53
    • Evans, L.1    Kenardy, J.2    Schneider, P.3    Hoey, H.4
  • 44
    • 0034697886 scopus 로고    scopus 로고
    • Efficacy of venlafaxine extended-release capsules in nondepressed outpatients with generalized anxiety disorder: A 6-month randomized controlled trial
    • Gelenberg AJ, Lydiard RB, Rudolph RL, et al., Efficacy of venlafaxine extended-release capsules in nondepressed outpatients with generalized anxiety disorder: a 6-month randomized controlled trial. J Am Med Assoc 2000; 283: 3082-3088.
    • (2000) J Am Med Assoc , vol.283 , pp. 3082-3088
    • Gelenberg, A.J.1    Lydiard, R.B.2    Rudolph, R.L.3
  • 45
    • 84929511999 scopus 로고    scopus 로고
    • A double-blind, randomized, placebo-controlled, fixed-dose phase III study of vilazodone in patients with generalized anxiety disorder
    • Gommoll C, Durgam S, Mathews M, et al., A double-blind, randomized, placebo-controlled, fixed-dose phase III study of vilazodone in patients with generalized anxiety disorder. Depress Anxiety 2015; 32: 451-459.
    • (2015) Depress Anxiety , vol.32 , pp. 451-459
    • Gommoll, C.1    Durgam, S.2    Mathews, M.3
  • 46
    • 14844291585 scopus 로고    scopus 로고
    • Escitalopram in the treatment of social anxiety disorder: Randomised, placebo-controlled, flexible-dosage study
    • Kasper S, Stein DJ, Loft H, Nil R,. Escitalopram in the treatment of social anxiety disorder: randomised, placebo-controlled, flexible-dosage study. Br J Psychiatry 2005; 186: 222-226.
    • (2005) Br J Psychiatry , vol.186 , pp. 222-226
    • Kasper, S.1    Stein, D.J.2    Loft, H.3    Nil, R.4
  • 47
    • 33646677754 scopus 로고    scopus 로고
    • Comparison of venlafaxine extended release versus paroxetine for treatment of patients with generalized anxiety disorder
    • Kim TS, Pae CU, Yoon SJ, et al., Comparison of venlafaxine extended release versus paroxetine for treatment of patients with generalized anxiety disorder. Psychiatry Clin Neurosci 2006; 60: 347-351.
    • (2006) Psychiatry Clin Neurosci , vol.60 , pp. 347-351
    • Kim, T.S.1    Pae, C.U.2    Yoon, S.J.3
  • 49
    • 0031712911 scopus 로고    scopus 로고
    • A multicentre double-blind comparison of hydroxyzine, buspirone and placebo in patients with generalized anxiety disorder
    • Lader M, Scotto JC,. A multicentre double-blind comparison of hydroxyzine, buspirone and placebo in patients with generalized anxiety disorder. Psychopharmacology (Berl) 1998; 139: 402-406.
    • (1998) Psychopharmacology (Berl) , vol.139 , pp. 402-406
    • Lader, M.1    Scotto, J.C.2
  • 50
    • 3543043767 scopus 로고    scopus 로고
    • Efficacy and tolerability of escitalopram in 12- and 24-week treatment of social anxiety disorder: Randomised, double-blind, placebo-controlled, fixed-dose study
    • Lader M, Stender K, Burger V, Nil R,. Efficacy and tolerability of escitalopram in 12- and 24-week treatment of social anxiety disorder: randomised, double-blind, placebo-controlled, fixed-dose study. Depress Anxiety 2004; 19: 241-248.
    • (2004) Depress Anxiety , vol.19 , pp. 241-248
    • Lader, M.1    Stender, K.2    Burger, V.3    Nil, R.4
  • 51
    • 0031049248 scopus 로고    scopus 로고
    • A comparison of paroxetine, clomipramine and placebo in the treatment of panic disorder. Collaborative Paroxetine Panic Study Investigators
    • Lecrubier Y, Bakker A, Dunbar G, Judge R,. A comparison of paroxetine, clomipramine and placebo in the treatment of panic disorder. Collaborative Paroxetine Panic Study Investigators. Acta Psychiatr Scand 1997; 95: 145-152.
    • (1997) Acta Psychiatr Scand , vol.95 , pp. 145-152
    • Lecrubier, Y.1    Bakker, A.2    Dunbar, G.3    Judge, R.4
  • 52
    • 0033632126 scopus 로고    scopus 로고
    • Citalopram controls phobic symptoms in patients with panic disorder: Randomized controlled trial
    • Leinonen E, Lepola U, Koponen H, et al., Citalopram controls phobic symptoms in patients with panic disorder: randomized controlled trial. J Psychiatry Neurosci 2000; 25: 24-32.
    • (2000) J Psychiatry Neurosci , vol.25 , pp. 24-32
    • Leinonen, E.1    Lepola, U.2    Koponen, H.3
  • 53
    • 0141990724 scopus 로고    scopus 로고
    • A double-blind, randomised, placebo controlled study of venlafaxine XL in patients with generalised anxiety disorder in primary care
    • Lenox-Smith AJ, Reynolds A,. A double-blind, randomised, placebo controlled study of venlafaxine XL in patients with generalised anxiety disorder in primary care. Br J Gen Pract 2003; 53: 772-777.
    • (2003) Br J Gen Pract , vol.53 , pp. 772-777
    • Lenox-Smith, A.J.1    Reynolds, A.2
  • 54
    • 1842866930 scopus 로고    scopus 로고
    • Controlled-release paroxetine in the treatment of patients with social anxiety disorder
    • Lepola U, Bergtholdt B, St Lambert J, Davy KL, Ruggiero L,. Controlled-release paroxetine in the treatment of patients with social anxiety disorder. J Clin Psychiatry 2004; 65: 222-229.
    • (2004) J Clin Psychiatry , vol.65 , pp. 222-229
    • Lepola, U.1    Bergtholdt, B.2    St Lambert, J.3    Davy, K.L.4    Ruggiero, L.5
  • 55
    • 0042306153 scopus 로고    scopus 로고
    • Efficacy of sertraline in severe generalized social anxiety disorder: Results of a double-blind, placebo-controlled study
    • Liebowitz MR, DeMartinis NA, Weihs K, et al., Efficacy of sertraline in severe generalized social anxiety disorder: results of a double-blind, placebo-controlled study. J Clin Psychiatry 2003; 64: 785-792.
    • (2003) J Clin Psychiatry , vol.64 , pp. 785-792
    • Liebowitz, M.R.1    DeMartinis, N.A.2    Weihs, K.3
  • 56
    • 13244255707 scopus 로고    scopus 로고
    • Venlafaxine extended release vs. Placebo and paroxetine in social anxiety disorder
    • Liebowitz MR, Gelenberg AJ, Munhack D,. Venlafaxine extended release vs. placebo and paroxetine in social anxiety disorder. Arch Gen Psychiatry 2005; 62: 190-198.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 190-198
    • Liebowitz, M.R.1    Gelenberg, A.J.2    Munhack, D.3
  • 57
    • 14644404240 scopus 로고    scopus 로고
    • SAD study group. A randomized controlled trial of venlafaxine extended release in generalized anxiety disorder
    • Liebowitz MR, Mangano RM, Bradwejn J, Asnis G, SAD study group. A randomized controlled trial of venlafaxine extended release in generalized anxiety disorder. J Clin Psychiatry 2005; 66: 238-247.
    • (2005) J Clin Psychiatry , vol.66 , pp. 238-247
    • Liebowitz, M.R.1    Mangano, R.M.2    Bradwejn, J.3    Asnis, G.4
  • 58
    • 0026516493 scopus 로고
    • Phenelzine vs. Atenolol in social phobia. A placebo-controlled comparison
    • Liebowitz MR, Schneier F, Campeas R, et al., Phenelzine vs. atenolol in social phobia. A placebo-controlled comparison. Arch Gen Psychiatry 1992; 49: 290-300.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 290-300
    • Liebowitz, M.R.1    Schneier, F.2    Campeas, R.3
  • 59
    • 0031808125 scopus 로고    scopus 로고
    • Sertraline in the treatment of panic disorder. A multi-site, double-blind, placebo-controlled, fixed-dose investigation
    • Londborg PD, Wolkow R, Smith WT, et al., Sertraline in the treatment of panic disorder. A multi-site, double-blind, placebo-controlled, fixed-dose investigation. Br J Psychiatry 1998; 173: 54-60.
    • (1998) Br J Psychiatry , vol.173 , pp. 54-60
    • Londborg, P.D.1    Wolkow, R.2    Smith, W.T.3
  • 60
    • 0027521901 scopus 로고
    • Preliminary report: Placebo-controlled, double-blind study of the clinical and metabolic effects of desipramine in panic disorder
    • Lydiard RB, Morton WA, Emmanuel NP, et al., Preliminary report: placebo-controlled, double-blind study of the clinical and metabolic effects of desipramine in panic disorder. Psychopharmacol Bull 1993; 29: 183-188.
    • (1993) Psychopharmacol Bull , vol.29 , pp. 183-188
    • Lydiard, R.B.1    Morton, W.A.2    Emmanuel, N.P.3
  • 61
    • 0028934076 scopus 로고
    • Imipramine treatment of panic disorder with agoraphobia: Dose ranging and plasma level-response relationships
    • Mavissakalian MR, Perel JM,. Imipramine treatment of panic disorder with agoraphobia: dose ranging and plasma level-response relationships. Am J Psychiatry 1995; 152: 673-682.
    • (1995) Am J Psychiatry , vol.152 , pp. 673-682
    • Mavissakalian, M.R.1    Perel, J.M.2
  • 62
    • 18244388510 scopus 로고    scopus 로고
    • Efficacy of usual antidepressant dosing regimens of fluoxetine in panic disorder: Randomised, placebo-controlled trial
    • Michelson D, Allgulander C, Dantendorfer K, et al., Efficacy of usual antidepressant dosing regimens of fluoxetine in panic disorder: randomised, placebo-controlled trial. Br J Psychiatry 2001; 179: 514-518.
    • (2001) Br J Psychiatry , vol.179 , pp. 514-518
    • Michelson, D.1    Allgulander, C.2    Dantendorfer, K.3
  • 63
    • 0031731533 scopus 로고    scopus 로고
    • Outcome assessment and clinical improvement in panic disorder: Evidence from a randomized controlled trial of fluoxetine and placebo. The Fluoxetine Panic Disorder Study Group
    • Michelson D, Lydiard RB, Pollack MH, et al., Outcome assessment and clinical improvement in panic disorder: evidence from a randomized controlled trial of fluoxetine and placebo. The Fluoxetine Panic Disorder Study Group. Am J Psychiatry 1998; 155: 1570-1577.
    • (1998) Am J Psychiatry , vol.155 , pp. 1570-1577
    • Michelson, D.1    Lydiard, R.B.2    Pollack, M.H.3
  • 64
    • 0026650901 scopus 로고
    • Superiority of clomipramine over imipramine in the treatment of panic disorder: A placebo-controlled trial
    • Modigh K, Westburg P, Eriksson E,. Superiority of clomipramine over imipramine in the treatment of panic disorder: a placebo-controlled trial. J Clin Psychopharmacol 1992; 12: 251-261.
    • (1992) J Clin Psychopharmacol , vol.12 , pp. 251-261
    • Modigh, K.1    Westburg, P.2    Eriksson, E.3
  • 65
    • 0030320611 scopus 로고    scopus 로고
    • Comparison of fluvoxamine, imipramine, and placebo in the treatment of outpatients with panic disorder
    • Nair NP, Bakish D, Saxena B, et al., Comparison of fluvoxamine, imipramine, and placebo in the treatment of outpatients with panic disorder. Anxiety 1996; 2: 192-198.
    • (1996) Anxiety , vol.2 , pp. 192-198
    • Nair, N.P.1    Bakish, D.2    Saxena, B.3
  • 66
    • 8644241902 scopus 로고    scopus 로고
    • Remission rates with venlafaxine extended release in Greek outpatients with generalized anxiety disorder. A double-blind, randomized, placebo controlled study
    • Nimatoudis I, Zissis NP, Kogeorgos J, et al., Remission rates with venlafaxine extended release in Greek outpatients with generalized anxiety disorder. A double-blind, randomized, placebo controlled study. Int Clin Psychopharmacol 2004; 19: 331-336.
    • (2004) Int Clin Psychopharmacol , vol.19 , pp. 331-336
    • Nimatoudis, I.1    Zissis, N.P.2    Kogeorgos, J.3
  • 67
    • 8944256864 scopus 로고
    • Paroxetine in the treatment of panic disorder. A randomised, double-blind, placebo-controlled study
    • Oehrberg S, Christiansen PE, Behnke K, et al., Paroxetine in the treatment of panic disorder. A randomised, double-blind, placebo-controlled study. Br J Psychiatry 1995; 167: 374-379.
    • (1995) Br J Psychiatry , vol.167 , pp. 374-379
    • Oehrberg, S.1    Christiansen, P.E.2    Behnke, K.3
  • 68
    • 0024561664 scopus 로고
    • Serotonergic anxiolytics in the treatment of panic disorder: A controlled study with buspirone
    • Pohl R, Balon R, Yeragani VK, Gershon S,. Serotonergic anxiolytics in the treatment of panic disorder: a controlled study with buspirone. Psychopathology 1989; 22 Suppl 1: 60-67.
    • (1989) Psychopathology , vol.22 , pp. 60-67
    • Pohl, R.1    Balon, R.2    Yeragani, V.K.3    Gershon, S.4
  • 69
    • 33847108539 scopus 로고    scopus 로고
    • A double-blind study of the efficacy of velafaxine extended-release, paroxetine, and placebo in the treatment of panic disorder
    • Pollack MH, Lepola U, Koponen H, et al., A double-blind study of the efficacy of velafaxine extended-release, paroxetine, and placebo in the treatment of panic disorder. Depress Anxiety 2007; 24: 1-14.
    • (2007) Depress Anxiety , vol.24 , pp. 1-14
    • Pollack, M.H.1    Lepola, U.2    Koponen, H.3
  • 70
    • 34648815011 scopus 로고    scopus 로고
    • A randomized controlled trial of velafaxine ER and paroxetine in the treatment of outpatients with panic disorder
    • Pollack M, Mangano R, Entusuah R, et al., A randomized controlled trial of velafaxine ER and paroxetine in the treatment of outpatients with panic disorder. Psychopharmacology (Berl) 2007; 194: 233-242.
    • (2007) Psychopharmacology (Berl) , vol.194 , pp. 233-242
    • Pollack, M.1    Mangano, R.2    Entusuah, R.3
  • 72
    • 0034965985 scopus 로고    scopus 로고
    • Paroxetine in the treatment of generalized anxiety disorder: Results of a placebo-controlled, flexible-dosage trial
    • Pollack MH, Zaninelli R, Goddard A, et al., Paroxetine in the treatment of generalized anxiety disorder: results of a placebo-controlled, flexible-dosage trial. J Clin Psychiatry 2001; 62: 350-357.
    • (2001) J Clin Psychiatry , vol.62 , pp. 350-357
    • Pollack, M.H.1    Zaninelli, R.2    Goddard, A.3
  • 73
    • 0034748048 scopus 로고    scopus 로고
    • Mirtazapine versus fluoxetine in the treatment of panic disorder
    • Ribeiro L, Busnello JV, Kauer-Sant'Anna M, et al., Mirtazapine versus fluoxetine in the treatment of panic disorder. Braz J Med Biol Res 2001; 34: 1303-1307.
    • (2001) Braz J Med Biol Res , vol.34 , pp. 1303-1307
    • Ribeiro, L.1    Busnello, J.V.2    Kauer-Sant'Anna, M.3
  • 74
    • 4644343737 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study of a flexible dose of venlafaxine ER in adult outpatients with generalized social anxiety disorder
    • Rickels K, Mangano R, Khan A,. A double-blind, placebo-controlled study of a flexible dose of venlafaxine ER in adult outpatients with generalized social anxiety disorder. J Clin Psychopharmacol 2004; 24: 488-496.
    • (2004) J Clin Psychopharmacol , vol.24 , pp. 488-496
    • Rickels, K.1    Mangano, R.2    Khan, A.3
  • 75
    • 0034044185 scopus 로고    scopus 로고
    • Efficacy of extended-release venlafaxine in nondepressed outpatients with generalized anxiety disorder
    • Rickels K, Pollack MH, Sheehan DV, Haskins JT,. Efficacy of extended-release venlafaxine in nondepressed outpatients with generalized anxiety disorder. Am J Psychiatry 2000; 157: 968-974.
    • (2000) Am J Psychiatry , vol.157 , pp. 968-974
    • Rickels, K.1    Pollack, M.H.2    Sheehan, D.V.3    Haskins, J.T.4
  • 76
    • 0038811891 scopus 로고    scopus 로고
    • Paroxetine treatment of generalized anxiety disorder: A double-blind placebo-controlled study
    • Rickels K, Zaninelli R, McCafferty J, Bellew K, Iyengar M, Sheehan D,. Paroxetine treatment of generalized anxiety disorder: a double-blind placebo-controlled study. Am J Psychiatry 2003; 160: 749-756.
    • (2003) Am J Psychiatry , vol.160 , pp. 749-756
    • Rickels, K.1    Zaninelli, R.2    McCafferty, J.3    Bellew, K.4    Iyengar, M.5    Sheehan, D.6
  • 77
    • 84870671939 scopus 로고    scopus 로고
    • Vortioxetine (Lu AA21004) 5 mg in generalized anxiety disorder: Results of an 8-week randomized, double-blind, placebo-controlled clinical trial in the United States
    • Rothschild AJ, Mahableshwarkar AR, Jacobsen P, Yan M, Sheehan DV,. Vortioxetine (Lu AA21004) 5 mg in generalized anxiety disorder: results of an 8-week randomized, double-blind, placebo-controlled clinical trial in the United States. Eur Neuropsychopharmacol 2012; 22: 858-866.
    • (2012) Eur Neuropsychopharmacol , vol.22 , pp. 858-866
    • Rothschild, A.J.1    Mahableshwarkar, A.R.2    Jacobsen, P.3    Yan, M.4    Sheehan, D.V.5
  • 78
    • 41849137610 scopus 로고    scopus 로고
    • Efficacy and safety of duloxetine in the treatment of generalized anxiety disorder: A flexible-dose, progressive-titration, placebo-controlled trial
    • Rynn M, Russell J, Erikson J, et al., Efficacy and safety of duloxetine in the treatment of generalized anxiety disorder: a flexible-dose, progressive-titration, placebo-controlled trial. Depress Anxiety 2008; 25: 182-189
    • (2008) Depress Anxiety , vol.25 , pp. 182-189
    • Rynn, M.1    Russell, J.2    Erikson, J.3
  • 79
    • 0027287576 scopus 로고
    • The relative efficacy of high-dose buspirone and alprazolam in the treatment of panic disorder: A double-blind placebo-controlled study
    • Sheehan DV, Raj AB, Harnett-Sheehan K, Soto S, Knapp E,. The relative efficacy of high-dose buspirone and alprazolam in the treatment of panic disorder: a double-blind placebo-controlled study. Acta Psychiatr Scand 1993; 88: 1-11.
    • (1993) Acta Psychiatr Scand , vol.88 , pp. 1-11
    • Sheehan, D.V.1    Raj, A.B.2    Harnett-Sheehan, K.3    Soto, S.4    Knapp, E.5
  • 80
    • 0345413412 scopus 로고    scopus 로고
    • Escitalopram in the treatment of panic disorder: A randomized, double-blind, placebo-controlled trial
    • Stahl SM, Gergel I, Li D,. Escitalopram in the treatment of panic disorder: a randomized, double-blind, placebo-controlled trial. J Clin Psychiatry 2003; 64: 1322-1327.
    • (2003) J Clin Psychiatry , vol.64 , pp. 1322-1327
    • Stahl, S.M.1    Gergel, I.2    Li, D.3
  • 81
    • 0032894805 scopus 로고    scopus 로고
    • Fluvoxamine treatment of social phobia (social anxiety disorder): A double-blind, placebo-controlled study
    • Stein MB, Fyer AJ, Davidson JR, Pollack MH, Wiita B,. Fluvoxamine treatment of social phobia (social anxiety disorder): a double-blind, placebo-controlled study. Am J Psychiatry 1999; 156: 756-760.
    • (1999) Am J Psychiatry , vol.156 , pp. 756-760
    • Stein, M.B.1    Fyer, A.J.2    Davidson, J.R.3    Pollack, M.H.4    Wiita, B.5
  • 82
    • 0032569245 scopus 로고    scopus 로고
    • Paroxetine treatment of generalized social phobia (social anxiety disorder): A randomized controlled trial
    • Stein MB, Liebowitz MR, Lydiard RB, et al., Paroxetine treatment of generalized social phobia (social anxiety disorder): a randomized controlled trial. J Am Med Assoc 1998; 280: 708-713.
    • (1998) J Am Med Assoc , vol.280 , pp. 708-713
    • Stein, M.B.1    Liebowitz, M.R.2    Lydiard, R.B.3
  • 83
    • 0035146313 scopus 로고    scopus 로고
    • Sertraline treatment of generalized social phobia: A 20-week, double-blind, placebo-controlled study
    • Van Ameringen MA, Lane RM, Walker JR, et al., Sertraline treatment of generalized social phobia: a 20-week, double-blind, placebo-controlled study. Am J Psychiatry 2001; 158: 275-281.
    • (2001) Am J Psychiatry , vol.158 , pp. 275-281
    • Van Ameringen, M.A.1    Lane, R.M.2    Walker, J.R.3
  • 84
    • 33847609653 scopus 로고    scopus 로고
    • Nefazodone in the treatment of generalized social phobia: A randomized, placebo-controlled trial
    • Van Ameringen M, Mancini C, Oakman J, et al., Nefazodone in the treatment of generalized social phobia: a randomized, placebo-controlled trial. J Clin Psychiatry 2007; 68: 288-295.
    • (2007) J Clin Psychiatry , vol.68 , pp. 288-295
    • Van Ameringen, M.1    Mancini, C.2    Oakman, J.3
  • 87
    • 1642539050 scopus 로고    scopus 로고
    • A double-blind placebo-controlled study of controlled release fluvoxamine for the treatment of generalized social anxiety disorder
    • Westenberg HG, Stein DJ, Yang H, Li D, Barbato LM,. A double-blind placebo-controlled study of controlled release fluvoxamine for the treatment of generalized social anxiety disorder. J Clin Psychopharmacol 2004; 24: 49-55.
    • (2004) J Clin Psychopharmacol , vol.24 , pp. 49-55
    • Westenberg, H.G.1    Stein, D.J.2    Yang, H.3    Li, D.4    Barbato, L.M.5
  • 88
    • 80054871307 scopus 로고    scopus 로고
    • Duloxetine versus placebo in the treatment of patients with generalized anxiety disorder in China
    • Wu W, Wang G, Ball S, Desaiah D, Ang Q,. Duloxetine versus placebo in the treatment of patients with generalized anxiety disorder in China. Chin Med J 2011; 124: 3260-3268.
    • (2011) Chin Med J , vol.124 , pp. 3260-3268
    • Wu, W.1    Wang, G.2    Ball, S.3    Desaiah, D.4    Ang, Q.5
  • 89
    • 34548584073 scopus 로고    scopus 로고
    • A systematic review of placebo response in studies of bipolar mania
    • Sysko R, Walsh BT,. A systematic review of placebo response in studies of bipolar mania. J Clin Psychiatry 2007; 68: 1213-1217.
    • (2007) J Clin Psychiatry , vol.68 , pp. 1213-1217
    • Sysko, R.1    Walsh, B.T.2
  • 90
    • 59749096824 scopus 로고    scopus 로고
    • Placebo response in randomized controlled trials of antidepressants for pediatric major depressive disorder
    • Bridge JA, Birmaher B, Iyengar S, Barbe RP, Brent DA,. Placebo response in randomized controlled trials of antidepressants for pediatric major depressive disorder. Am J Psychiatry 2009; 166: 42-49.
    • (2009) Am J Psychiatry , vol.166 , pp. 42-49
    • Bridge, J.A.1    Birmaher, B.2    Iyengar, S.3    Barbe, R.P.4    Brent, D.A.5
  • 91
    • 84887478908 scopus 로고    scopus 로고
    • Meta-regression analysis of placebo response in antipsychotic trials, 1970-2010
    • Agid O, Siu CO, Potkin SG, et al., Meta-regression analysis of placebo response in antipsychotic trials, 1970-2010. Am J Psychiatry 2013; 170: 1335-1344.
    • (2013) Am J Psychiatry , vol.170 , pp. 1335-1344
    • Agid, O.1    Siu, C.O.2    Potkin, S.G.3
  • 92
    • 84887500644 scopus 로고    scopus 로고
    • Increasing placebo response in antipsychotic drug trials: Let's stop the vicious circle
    • Leucht S, Heres S, Davis JM,. Increasing placebo response in antipsychotic drug trials: let's stop the vicious circle. Am J Psychiatry 2013; 170: 1232-1234.
    • (2013) Am J Psychiatry , vol.170 , pp. 1232-1234
    • Leucht, S.1    Heres, S.2    Davis, J.M.3
  • 93
    • 0025037021 scopus 로고
    • Characteristics of placebo response during long-term treatment of panic disorder
    • Dager SR, Khan A, Cowley D, et al., Characteristics of placebo response during long-term treatment of panic disorder. Psychopharmacol Bull 1990; 26: 273-278.
    • (1990) Psychopharmacol Bull , vol.26 , pp. 273-278
    • Dager, S.R.1    Khan, A.2    Cowley, D.3
  • 94
    • 0025155253 scopus 로고
    • Drug treatment of panic disorder: Early response to treatment as a predictor of final outcome
    • Albus M, Lecrubier Y, Maier W, et al., Drug treatment of panic disorder: early response to treatment as a predictor of final outcome. Acta Psychiatr Scand 1990; 82: 359-365.
    • (1990) Acta Psychiatr Scand , vol.82 , pp. 359-365
    • Albus, M.1    Lecrubier, Y.2    Maier, W.3
  • 95
    • 0027933111 scopus 로고
    • Does a placebo run-in or a placebo treatment cell affect the efficacy of antidepressant medications?
    • Trivedi M, Rush J,. Does a placebo run-in or a placebo treatment cell affect the efficacy of antidepressant medications? Neuropsychopharmacology 1995; 11: 33-43.
    • (1995) Neuropsychopharmacology , vol.11 , pp. 33-43
    • Trivedi, M.1    Rush, J.2
  • 96
    • 33746910224 scopus 로고    scopus 로고
    • Rater bias in a blinded randomized placebo-controlled psychiatry trial
    • Marcus SM, Gorman JM, Tu X,. Rater bias in a blinded randomized placebo-controlled psychiatry trial. Stat Med 2006; 25: 2762-2770.
    • (2006) Stat Med , vol.25 , pp. 2762-2770
    • Marcus, S.M.1    Gorman, J.M.2    Tu, X.3
  • 97
    • 33846245890 scopus 로고    scopus 로고
    • Why do clinical trials fail? the problem of measurement error in clinical trials: Time to test new paradigms?
    • Kobak KA, Kane JM, Thase ME, Nierenberg AA,. Why do clinical trials fail? The problem of measurement error in clinical trials: time to test new paradigms? J Clin Psychopharmacol 2007; 27: 1-5.
    • (2007) J Clin Psychopharmacol , vol.27 , pp. 1-5
    • Kobak, K.A.1    Kane, J.M.2    Thase, M.E.3    Nierenberg, A.A.4
  • 98
    • 84857071610 scopus 로고    scopus 로고
    • Antidepressant clinical trials and subject recruitment: Just who are symptomatic volunteers?
    • Brody B, Leon AC, Kocsis JH,. Antidepressant clinical trials and subject recruitment: just who are symptomatic volunteers? Am J Psychiatry 2011; 168: 1245-1247.
    • (2011) Am J Psychiatry , vol.168 , pp. 1245-1247
    • Brody, B.1    Leon, A.C.2    Kocsis, J.H.3
  • 99
    • 34147198524 scopus 로고    scopus 로고
    • Therapeutic effect of follow-up assessments on antidepressant and placebo response rates in antidepressant efficacy trials
    • Posternak MA, Zimmerman M,. Therapeutic effect of follow-up assessments on antidepressant and placebo response rates in antidepressant efficacy trials. Br J Psychiatry 2007; 190: 287-292.
    • (2007) Br J Psychiatry , vol.190 , pp. 287-292
    • Posternak, M.A.1    Zimmerman, M.2


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