Ent-Abietane-type diterpenoids from the roots of Euphorbia ebracteolata with their inhibitory activities on LPS-induced NO production in RAW 264.7 macrophages

Bioorganic and Medicinal Chemistry Letters

Volumn 26, Issue 1, 2016, Pages 1-5

  Liu, Zhi Guo ^a   Li, Zhan Lin ^a   Li, Da Hong ^a   Li, Ning ^a   Bai, Jiao ^a   Zhao, Feng ^b   Meng, Da Li ^a   Hua, Hui Ming ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b YANTAI UNIVERSITY   (China)

Author keywords

Anti inflammation; Ent abietane diterpenoids; Euphorbia ebracteolata

Indexed keywords

11BETA HYDROXY 8,14 EPOXY ENT ABIETA 13(15)EN 16,12BETA OLIDE; 11BETA HYDROXY ENT ABIETA 8(14),13915)DIEN 16,12BETA OLIDE; ABIETANE DERIVATIVE; ANTIINFLAMMATORY AGENT; DITERPENOID; JOLKINOLIDE A; JOLKINOLIDE B; LIPOPOLYSACCHARIDE; NITRIC OXIDE; UNCLASSIFIED DRUG; YUEXIANDAJISU D; YUEXIANDAJISU E;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; EUPHORBIA; EUPHORBIA EBRACTEOLATA; HETERONUCLEAR MULTIPLE BOND CORRELATION; HUMAN; HUMAN CELL; IC50; MACROPHAGE; NUCLEAR MAGNETIC RESONANCE; PLANT ROOT; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TISSUES; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CHEMISTRY; CONFORMATION; DOSE RESPONSE; DRUG EFFECTS; ISOLATION AND PURIFICATION; METABOLISM; MOUSE;

ANIMALS; DITERPENES, ABIETANE; DOSE-RESPONSE RELATIONSHIP, DRUG; EUPHORBIA; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MOLECULAR CONFORMATION; NITRIC OXIDE; PLANT ROOTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84949543515     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.11.080     Document Type: Article

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