Cytotoxic diterpenoids from the roots of Euphorbia ebracteolata

Planta Medica

Volumn 71, Issue 4, 2005, Pages 349-354

  Shi, Hai Ming ^a   Williams, Ian D ^b   Sung, Herman H Y ^b   Zhu, Hua Xu ^a   Ip, Nancy Y ^b   Min, Zhi Da ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

Cytotoxic activity; Diterpenoids; Euphorbia ebracteolata; Euphorbiaceae; Yuexiandajisus D F

Indexed keywords

DITERPENOID; ENT 11ALPHA HYDROXYABIETA 8(14),13(15) DIEN 16,12ALPHA OLIDE; ENT 13 HYDROXYATIS 16 ENE 3,14 DIONE; ENT 16ALPHA,17 DIHYDROXYATISAN 3 ONE; ENT 3 OXOKAURANE 16ALPHA,17 DIOL; ENT 3BETA DIHDROXYATIS 16 EN 14 ONE; ENT ATISANE 3BETA,16ALPHA,17 TRIOL; EUPHORBIA EXTRACT; JOLKINOLIDE A; JOLKINOLIDE B; UNCLASSIFIED DRUG; YUEXIANDAJISU;

ARTICLE; CYTOTOXICITY; EUPHORBIA; EUPHORBIA EBRACTEOLATA; HUMAN; HUMAN CELL; IC 50; PLANT ROOT; SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; TUMOR CELL; X RAY DIFFRACTION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; DITERPENES; EUPHORBIA; HUMANS; INHIBITORY CONCENTRATION 50; MICE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; STRUCTURE-ACTIVITY RELATIONSHIP; X-RAY DIFFRACTION;

EUPHORBIA; EUPHORBIA EBRACTEOLATA; EUPHORBIACEAE;

EID: 18744401356     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-864102     Document Type: Article

References (18)

1. Jiangsu College of New Medicine. A Dictionary of the Traditional Chinese Medicines. Shanghai Science and Technology Press, Shanghai; 1986: p 1898
2. Wang WX, Ding XB. Studies on diterpenoids from the roots of Euphorbia ebracteolata. Acta Pharmaceutica Sinica 1998; 33: 128-31
3. Xu ZH, Sun J, Xu RS, Qin GW. Casbane diterpenoids from Euphorbia ebracteolata. Phytochemistry 1998; 49: 149-51
4. Xu ZH, Qin GW, Xu RS. An isopimarane diterpene from Euphorbia ebracteolata Hayata. Journal of Asian Natural Products Research 2000; 2: 257-61
5. Zhang HQ, Ding YM, Chen GY, Dong YF, Zhu YL. Studies on active constituents of root of Euphorbia ebracteolata Hayata. Acta Botanica Sinica 1987; 29: 429-31
6. Dong YF, Ding YM. Acylploroglucinol derivatives from the root of Euphorbia ebracteolata Hayata. Journal of Plant Resources and Environment 1992; 1: 1-3
7. Zhang HQ, Ding YM. Studies on the active compounds B and C in the root of Euphorbia ebracteolata Hayata. Journal of Plant Resources and Environment 1992; 1: 6-9
8. Lee SC, Ahn BT, Park WY, Lee SH, Ro JS, Lee KS, Ryu EK. Pharmacognostic study on Euphorbia ebracteolata (1). Flavonoid constituents. Saengyak Hakhoechi 1992; 23: 126-31
9. Ahn BT, Lee SC, Park WY, Lee SH, Ro JS, Lee KS, Ryu EK. Pharmacognostic study on Euphorbia ebracteolata (II). On the chemical study of the tannins and related compounds. Saengyak Hakhoechi 1992; 23: 211-7
10. Ahn BT, Oh KJ, Ro JS, Lee KS. A new flavonoid from Euphorbia ebracteolata. Planta Medica 1996; 62: 383-4
11. Ahn BT, Lee KS. Phenolic compounds from Euphorbia ebracteolata. Saengyak Hakhoechi 1996; 27: 136-41
12. Mdee LK, Waibel R, Nkunya MHH, Jonker SA, Achenbach H. Rosane diterpenes and bis-dinorditerpenes from Hugonia casteneifolia. Phytochemistry 1998; 49: 1107-13
13. Lal AR, Cambie RC, Rutledge PS, Woodgate PD. Ent-pimarane and Ent-abietane diterpenes from Euphorbia fidjiana. Phytochemistry 1990; 29: 2239-46
14. Lal AR, Cambie RC, Rutledge PS, Woodgate PD. Ent-atisane diterpenes from Euphorbia fidjiana. Phytochemistry 1990; 29: 1925-35
15. Ding YL, Jia ZJ. Tetracyclic diterpenols from Euphorbia sieboldiana. Phytochemistry 1991; 30: 2413-5
16. Satti NK, Suri OP, Thaper RK, Kachroo PL. Ent-atisane-3β,16α, 17-triol, a diterpene from Euphorbia acaulis. Phytochemistry 1988; 27: 1530-1
17. Kigoshi H, Ichino T, Yamada K, Ijuin Y, Makita SF, Uemura D. Stereo-structure and Bioactivities of Jolkinolide D. Chemistry Letters 2001; 30: 518-9
18. Che CT, Zhou TX, Ma QG, Qin GW, Williams ID, Wu HM, Shi ZS. Diterpenes and aromatic compounds from Euphorbia fischeriana. Phytochemistry 1999; 52: 117-21