메뉴 건너뛰기




Volumn 28, Issue 12, 2015, Pages 1535-1544

Tumor PD-L1 expression, immune cell correlates and PD-1+ lymphocytes in sentinel lymph node melanoma metastases

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; LYMPHOCYTE ANTIBODY; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; TRANSCRIPTION FACTOR FOXP3; CD274 PROTEIN, HUMAN; PDCD1 PROTEIN, HUMAN; TUMOR MARKER;

EID: 84949539261     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2015.110     Document Type: Article
Times cited : (73)

References (39)
  • 1
    • 84893730461 scopus 로고    scopus 로고
    • Final trial report of sentinel-node biopsy versus nodal observation in melanoma
    • Morton DL, Thompson JF, Cochran AJ, et al. Final trial report of sentinel-node biopsy versus nodal observation in melanoma. New Engl J Med 2014; 370: 599-609
    • (2014) New Engl J Med , vol.370 , pp. 599-609
    • Morton, D.L.1    Thompson, J.F.2    Cochran, A.J.3
  • 2
    • 74949143594 scopus 로고    scopus 로고
    • Final version of 2009 AJCC melanoma staging and classification
    • Balch CM, Gershenwald JE, Soong S-j, et al. Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol 2009 27: 6199-6206
    • (2009) J Clin Oncol , vol.27 , pp. 6199-6206
    • Balch, C.M.1    Gershenwald, J.E.2    Soong, S.-J.3
  • 3
    • 46749103710 scopus 로고    scopus 로고
    • Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: Final results of EORTC 18991 a randomised phase III trial
    • Eggermont AM, Suciu S, Santinami M, et al. Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial. Lancet 2008; 372: 117-126
    • (2008) Lancet , vol.372 , pp. 117-126
    • Eggermont, A.M.1    Suciu, S.2    Santinami, M.3
  • 4
    • 77950576363 scopus 로고    scopus 로고
    • Interferon alpha adjuvant therapy in patients with high-risk melanoma: A systematic review and meta-Analysis
    • Mocellin S, Pasquali S, Rossi CR, et al. Interferon alpha adjuvant therapy in patients with high-risk melanoma: a systematic review and meta-Analysis. J Nat Cancer I 2010; 102: 493-501
    • (2010) J Nat Cancer i , vol.102 , pp. 493-501
    • Mocellin, S.1    Pasquali, S.2    Rossi, C.R.3
  • 5
    • 0030030347 scopus 로고    scopus 로고
    • Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: The Eastern Cooperative Oncology Group Trial EST 1684
    • Kirkwood JM, Strawderman MH, Ernstoff MS, et al. Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684. J Clin Oncol 1996; 14: 7-17
    • (1996) J Clin Oncol , vol.14 , pp. 7-17
    • Kirkwood, J.M.1    Strawderman, M.H.2    Ernstoff, M.S.3
  • 6
    • 1842533233 scopus 로고    scopus 로고
    • A pooled analysis of eastern cooperative oncology group and intergroup trials of adjuvant high-dose interferon for melanoma
    • Kirkwood JM, Manola J, Ibrahim J, et al. A pooled analysis of eastern cooperative oncology group and intergroup trials of adjuvant high-dose interferon for melanoma. Clin Cancer Res 2004; 10: 1670-1677
    • (2004) Clin Cancer Res , vol.10 , pp. 1670-1677
    • Kirkwood, J.M.1    Manola, J.2    Ibrahim, J.3
  • 7
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. New Engl J Med 2010; 363: 711-723
    • (2010) New Engl J Med , vol.363 , pp. 711-723
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3
  • 8
    • 79959795786 scopus 로고    scopus 로고
    • Improved survival with vemurafenib in melanoma with BRAF V600E mutation
    • Chapman PB, Hauschild A, Robert C, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. New Engl J Med 2011; 364: 2507-2516
    • (2011) New Engl J Med , vol.364 , pp. 2507-2516
    • Chapman, P.B.1    Hauschild, A.2    Robert, C.3
  • 9
    • 84864285704 scopus 로고    scopus 로고
    • Dabrafenib in BRAF-mutated metastatic melanoma: A multicentre, open-label, phase 3 randomised controlled trial
    • Hauschild A, Grob J-J, Demidov LV, et al. Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial. Lancet 2012; 380: 358-365
    • (2012) Lancet , vol.380 , pp. 358-365
    • Hauschild, A.1    Grob, J.-J.2    Demidov, L.V.3
  • 10
    • 84908257665 scopus 로고    scopus 로고
    • Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma
    • Long GV, Stroyakovskiy D, Gogas H, et al. Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma. New Engl J Med 2014; 371: 1877-1888
    • (2014) New Engl J Med , vol.371 , pp. 1877-1888
    • Long, G.V.1    Stroyakovskiy, D.2    Gogas, H.3
  • 11
    • 84920394727 scopus 로고    scopus 로고
    • Improved overall survival in melanoma with combined dabrafenib and trametinib
    • Robert C, Karaszewska B, Schachter J, et al. Improved overall survival in melanoma with combined dabrafenib and trametinib. New Engl J Med 2015; 372: 30-39
    • (2015) New Engl J Med , vol.372 , pp. 30-39
    • Robert, C.1    Karaszewska, B.2    Schachter, J.3
  • 12
    • 84908245075 scopus 로고    scopus 로고
    • Combined vemurafenib and cobimetinib in BRAF-mutated melanoma
    • Larkin J, Ascierto PA, Dréno B, et al. Combined vemurafenib and cobimetinib in BRAF-mutated melanoma. New Engl J Med 2014; 371: 1867-1876
    • (2014) New Engl J Med , vol.371 , pp. 1867-1876
    • Larkin, J.1    Ascierto, P.A.2    Dréno, B.3
  • 13
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. New Engl J Med 2012; 366: 2443-2454
    • (2012) New Engl J Med , vol.366 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3
  • 14
    • 84879759020 scopus 로고    scopus 로고
    • Safety and tumor responses with lambrolizumab (anti-pd-1) in melanoma
    • Hamid O, Robert C, Daud A, et al. Safety and Tumor Responses with Lambrolizumab (Anti-PD-1) in Melanoma. New Engl J Med 2013; 369: 134-144
    • (2013) New Engl J Med , vol.369 , pp. 134-144
    • Hamid, O.1    Robert, C.2    Daud, A.3
  • 15
    • 0026700235 scopus 로고
    • Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death
    • Ishida Y, Agata Y, Shibahara K, et al. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J 1992; 11: 3887
    • (1992) EMBO J , vol.11 , pp. 3887
    • Ishida, Y.1    Agata, Y.2    Shibahara, K.3
  • 16
    • 42649125225 scopus 로고    scopus 로고
    • PD-1 and its ligands in tolerance and immunity
    • Keir ME, Butte MJ, Freeman GJ, et al. PD-1 and its ligands in tolerance and immunity. Annu Rev Immunol 2008; 26: 677-704
    • (2008) Annu Rev Immunol , vol.26 , pp. 677-704
    • Keir, M.E.1    Butte, M.J.2    Freeman, G.J.3
  • 17
    • 0034596948 scopus 로고    scopus 로고
    • Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
    • Freeman GJ, Long AJ, Iwai Y, et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 2000; 192: 1027-1034
    • (2000) J Exp Med , vol.192 , pp. 1027-1034
    • Freeman, G.J.1    Long, A.J.2    Iwai, Y.3
  • 18
    • 0032736029 scopus 로고    scopus 로고
    • B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
    • Dong H, Zhu G, Tamada K, et al. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med 1999; 5: 1365-1369
    • (1999) Nat Med , vol.5 , pp. 1365-1369
    • Dong, H.1    Zhu, G.2    Tamada, K.3
  • 19
    • 5844264920 scopus 로고    scopus 로고
    • PD-L2 is a second ligand for PD-1 and inhibits T cell activation
    • Latchman Y, Wood CR, Chernova T, et al. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol 2001; 2: 261-268
    • (2001) Nat Immunol , vol.2 , pp. 261-268
    • Latchman, Y.1    Wood, C.R.2    Chernova, T.3
  • 20
    • 0035794314 scopus 로고    scopus 로고
    • B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells
    • Tseng S-Y, Otsuji M, Gorski K, et al. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J Exp Med 2001; 193: 839-846
    • (2001) J Exp Med , vol.193 , pp. 839-846
    • Tseng, S.-Y.1    Otsuji, M.2    Gorski, K.3
  • 21
    • 0037111483 scopus 로고    scopus 로고
    • Expression of programmed death 1 ligands by murine T cells and APC
    • Yamazaki T, Akiba H, Iwai H, et al. Expression of programmed death 1 ligands by murine T cells and APC. J Immunol 2002; 169: 5538-5545
    • (2002) J Immunol , vol.169 , pp. 5538-5545
    • Yamazaki, T.1    Akiba, H.2    Iwai, H.3
  • 22
    • 0037126021 scopus 로고    scopus 로고
    • Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
    • Iwai Y, Ishida M, Tanaka Y, et al. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci USA 2002; 99: 12293-12297
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12293-12297
    • Iwai, Y.1    Ishida, M.2    Tanaka, Y.3
  • 23
    • 18544380239 scopus 로고    scopus 로고
    • Tumor-Associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
    • Dong H, Strome SE, Salomao DR, et al. Tumor-Associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med 2002; 8: 793-800
    • (2002) Nat Med , vol.8 , pp. 793-800
    • Dong, H.1    Strome, S.E.2    Salomao, D.R.3
  • 24
    • 84863393623 scopus 로고    scopus 로고
    • Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma
    • Wilmott JS, Long GV, Howle JR, et al. Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma. Clin Cancer Res 2012; 18: 1386-1394
    • (2012) Clin Cancer Res , vol.18 , pp. 1386-1394
    • Wilmott, J.S.1    Long, G.V.2    Howle, J.R.3
  • 25
    • 84937629331 scopus 로고    scopus 로고
    • PD-L1 Expression and tumor-infiltrating lymphocytes define different subsets of mapk inhibitor-treated melanoma patients
    • Kakavand H, Wilmott JS, Menzies AM, et al. PD-L1 Expression and Tumor-Infiltrating Lymphocytes Define Different Subsets of MAPK Inhibitor-Treated Melanoma Patients. Clin Cancer Res 2015; 21: 3140-3148
    • (2015) Clin Cancer Res , vol.21 , pp. 3140-3148
    • Kakavand, H.1    Wilmott, J.S.2    Menzies, A.M.3
  • 26
    • 84920956732 scopus 로고    scopus 로고
    • PD-1 blockade induces responses by inhibiting adaptive immune resistance
    • Tumeh PC, Harview CL, Yearley JH, et al. PD-1 blockade induces responses by inhibiting adaptive immune resistance. Nature 2014; 515: 568-571
    • (2014) Nature , vol.515 , pp. 568-571
    • Tumeh, P.C.1    Harview, C.L.2    Yearley, J.H.3
  • 27
    • 33749053823 scopus 로고    scopus 로고
    • Sentinelnode biopsy or nodal observation in melanoma
    • Morton DL, Thompson JF, Cochran AJ, et al. Sentinelnode biopsy or nodal observation in melanoma. New Engl J Med 2006; 355: 1307-1317
    • (2006) New Engl J Med , vol.355 , pp. 1307-1317
    • Morton, D.L.1    Thompson, J.F.2    Cochran, A.J.3
  • 28
    • 84907521156 scopus 로고    scopus 로고
    • Ipilimumab versus placebo after complete resection of stage III melanoma: Initial efficacy and safety results from the EORTC 18071 phase III trial
    • Chicago, IL, USA. American Society of Clinical Oncology Chicago, IL, USA, 2014
    • Eggermont AM (ed). Ipilimumab versus placebo after complete resection of stage III melanoma: Initial efficacy and safety results from the EORTC 18071 phase III trial. Proceedings of the ASCO Annual Meeting; 30 May-03 June 2014; Chicago, IL, USA. American Society of Clinical Oncology: Chicago, IL, USA, 2014
    • (2014) Proceedings of the ASCO Annual Meeting; 30 May-03 June
    • Eggermont, A.M.1
  • 29
    • 84926678589 scopus 로고    scopus 로고
    • PD-L1 expression in melanoma shows marked heterogeneity within and between patients: Implications for anti-PD-1/PD-L1 clinical trials
    • Madore J, Vilain RE, Menzies AM, et al. PD-L1 expression in melanoma shows marked heterogeneity within and between patients: implications for anti-PD-1/PD-L1 clinical trials. Pigm Cell Mel Res 2014; 28: 245-253
    • (2014) Pigm Cell Mel Res , vol.28 , pp. 245-253
    • Madore, J.1    Vilain, R.E.2    Menzies, A.M.3
  • 30
    • 84859128199 scopus 로고    scopus 로고
    • Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape
    • 127ra37-1ra37r
    • Taube JM, Anders RA, Young GD, et al. Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Sci Transl Med 2012; 4: 127ra37-1ra37r
    • (2012) Sci Transl Med , vol.4
    • Taube, J.M.1    Anders, R.A.2    Young, G.D.3
  • 31
    • 79955518331 scopus 로고    scopus 로고
    • Overall survival and PD-L1 expression in metastasized malignant melanoma
    • Gadiot J, Hooijkaas AI, Kaiser ADM, et al. Overall survival and PD-L1 expression in metastasized malignant melanoma. Cancer 2011; 117: 2192-2201
    • (2011) Cancer , vol.117 , pp. 2192-2201
    • Gadiot, J.1    Hooijkaas, A.I.2    Kaiser, A.D.M.3
  • 32
    • 84925222119 scopus 로고    scopus 로고
    • Nivolumab in previously untreated melanoma without BRAF mutation
    • Robert C, Long GV, Brady B, et al. Nivolumab in previously untreated melanoma without BRAF mutation. New Engl J Med 2015; 372: 320-330
    • (2015) New Engl J Med , vol.372 , pp. 320-330
    • Robert, C.1    Long, G.V.2    Brady, B.3
  • 33
    • 84907973066 scopus 로고    scopus 로고
    • Clinical efficacy and correlation with tumor PD-L1 expression in patients (pts) with melanoma (MEL) treated with the anti-PD-1 monoclonal antibody MK-3475
    • 30 May-03 June Chicago, IL, USA. American Society of Clinical Oncology Chicago, IL, USA, 2014
    • Kefford R (ed). Clinical efficacy and correlation with tumor PD-L1 expression in patients (pts) with melanoma (MEL) treated with the anti-PD-1 monoclonal antibody MK-3475. Proceedings of the ASCO Annual Meeting; 30 May-03 June 2014; Chicago, IL, USA. American Society of Clinical Oncology: Chicago, IL, USA, 2014
    • (2014) Proceedings of the ASCO Annual Meeting
    • Kefford, R.1
  • 34
    • 84949532353 scopus 로고    scopus 로고
    • A study of MPDL3280A, an engineered PD-L1 antibody in patients with locally advanced or metastatic tumors
    • 31 May-04 June Chicago, IL, USA. American Society of Clinical Oncology Chicago, IL, USA, 2013
    • Herbst RS (ed). A study of MPDL3280A, an engineered PD-L1 antibody in patients with locally advanced or metastatic tumors. Proceedings of the ASCO Annual Meeting; 31 May-04 June 2013; Chicago, IL, USA. American Society of Clinical Oncology: Chicago, IL, USA, 2013
    • (2013) Proceedings of the ASCO Annual Meeting
    • Herbst, R.S.1
  • 35
    • 84920956735 scopus 로고    scopus 로고
    • Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
    • Herbst RS, Soria J-C, Kowanetz M, et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature 2014; 515: 563-567
    • (2014) Nature , vol.515 , pp. 563-567
    • Herbst, R.S.1    Soria, J.-C.2    Kowanetz, M.3
  • 36
    • 84864059882 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocyte grade is an independent predictor of sentinel lymph node status and survival in patients with cutaneous melanoma
    • Azimi F, Scolyer RA, Rumcheva P, et al. Tumor-Infiltrating Lymphocyte Grade Is an Independent Predictor of Sentinel Lymph Node Status and Survival in Patients With Cutaneous Melanoma. J Clin Oncol 2012; 30: 2678-2683
    • (2012) J Clin Oncol , vol.30 , pp. 2678-2683
    • Azimi, F.1    Scolyer, R.A.2    Rumcheva, P.3
  • 37
    • 0029925375 scopus 로고    scopus 로고
    • Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma
    • Clemente CG, Mihm MC, Bufalino R, et al. Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma. Cancer 1996; 77: 1303-1310
    • (1996) Cancer , vol.77 , pp. 1303-1310
    • Clemente, C.G.1    Mihm, M.C.2    Bufalino, R.3
  • 38
    • 0030052833 scopus 로고    scopus 로고
    • Tumor infiltrating lymphocytes in lymph node melanoma metastases: A histopathologic prognostic indicator and an expression of local immune response
    • Mihm MC Jr, Clemente CG, Cascinelli N. Tumor infiltrating lymphocytes in lymph node melanoma metastases: a histopathologic prognostic indicator and an expression of local immune response. Lab Invest 1996; 74: 43-47
    • (1996) Lab Invest , vol.74 , pp. 43-47
    • Mihm, M.C.1    Clemente, C.G.2    Cascinelli, N.3
  • 39
    • 3142737258 scopus 로고    scopus 로고
    • Foxp3 expressing CD4+ CD25high regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells
    • Viguier M, Lemaître F, Verola O, et al. Foxp3 expressing CD4+ CD25high regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells. J Immunol 2004; 173: 1444-1453
    • (2004) J Immunol , vol.173 , pp. 1444-1453
    • Viguier, M.1    Lemaître, F.2    Verola, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.