Parainfluenza virus infections in hematopoietic cell transplant recipients and hematologic malignancy patients: A systematic review

Cancer Letters

Volumn 370, Issue 2, 2016, Pages 358-364

  Shah, Dimpy P ^a   Shah, Pankil K ^a   Azzi, Jacques M ^a   Chemaly, Roy F ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Antiviral therapy; Cancer; Leukemia; PIV; Pneumonia; Stem cell transplant

Indexed keywords

ANTIVIRUS AGENT; BCX 2798; BCX 2855; DAS 181; IMMUNOGLOBULIN; PARAINFLUENZA VACCINE; RIBAVIRIN; UNCLASSIFIED DRUG;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANTIVIRAL THERAPY; ASYMPTOMATIC INFECTION; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; BRONCHIOLITIS OBLITERANS; HAND WASHING; HEMATOLOGIC MALIGNANCY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HOSPITAL INFECTION; HUMAN; IMMUNOCOMPROMISED PATIENT; INCIDENCE; INFECTION CONTROL; LABORATORY DIAGNOSIS; LOWER RESPIRATORY TRACT INFECTION; LUNG BIOPSY; MORTALITY; PARAINFLUENZA VIRUS INFECTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTECTIVE EQUIPMENT; SHORT SURVEY; SYSTEMATIC REVIEW; VIRAL RESPIRATORY TRACT INFECTION; ADVERSE EFFECTS; COMPLICATION; HEMATOLOGIC DISEASE; PARAMYXOVIRIDAE INFECTIONS; RISK FACTOR;

ANTIVIRAL AGENTS; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; INCIDENCE; PARAMYXOVIRIDAE INFECTIONS; RISK FACTORS;

EID: 84949532990     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2015.11.014     Document Type: Review

References (55)

1. Chemaly R.F., Hanmod S.S., Rathod D.B., Ghantoji S.S., Jiang Y., Doshi A., et al. The characteristics and outcomes of parainfluenza virus infections in 200 patients with leukemia or recipients of hematopoietic stem cell transplantation. Blood 2012, 119:2738-2745. quiz 2969.
2. Chakrabarti S., Avivi I., Mackinnon S., Ward K., Kottaridis P.D., Osman H., et al. Respiratory virus infections in transplant recipients after reduced-intensity conditioning with Campath-1H: high incidence but low mortality. Br. J. Haematol 2002, 119:1125-1132.
3. Fazekas T., Eickhoff P., Rauch M., Verdianz M., Attarbaschi A., Dworzak M., et al. Prevalence and clinical course of viral upper respiratory tract infections in immunocompromised pediatric patients with malignancies or after hematopoietic stem cell transplantation. J. Pediatr. Hematol. Oncol 2012, 34:442-449.
4. Wasserman R., August C.S., Plotkin S.A. Viral infections in pediatric bone marrow transplant patients. Pediatr. Infect. Dis. J. 1988, 7:109-115.
5. Lujan-Zilbermann J., Benaim E., Tong X., Srivastava D.K., Patrick C.C., DeVincenzo J.P. Respiratory virus infections in pediatric hematopoietic stem cell transplantation. Clin. Infect. Dis 2001, 33:962-968.
6. Srinivasan A., Wang C., Yang J., Shenep J.L., Leung W.H., Hayden R.T. Symptomatic parainfluenza virus infections in children undergoing hematopoietic stem cell transplantation. Biol. Blood Marrow Transplant 2011, 17:1520-1527.
7. Lee J.H., Jang J.H., Lee S.H., Kim Y.J., Yoo K.H., Sung K.W., et al. Respiratory viral infections during the first 28 days after transplantation in pediatric hematopoietic stem cell transplant recipients. Clin. Transplant 2012, 26:736-740.
8. Choi J.H., Choi E.H., Kang H.J., Park K.D., Park S.S., Shin H.Y., et al. Respiratory viral infections after hematopoietic stem cell transplantation in children. J. Korean Med. Sci 2013, 28:36-41.
9. Srinivasan A., Gu Z.M., Smith T., Morgenstern M., Sunkara A., Kang G.L., et al. Prospective detection of respiratory pathogens in symptomatic children with cancer. Pediatr. Infect. Dis. J. 2013, 32:E99-E104.
10. Lewis V.A., Champlin R., Englund J., Couch R., Goodrich J.M., Rolston K., et al. Respiratory disease due to parainfluenza virus in adult bone marrow transplant recipients. Clin. Infect. Dis 1996, 23:1033-1037.
11. Whimbey E., Champlin R.E., Couch R.B., Englund J.A., Goodrich J.M., Raad I., et al. Community respiratory virus infections among hospitalized adult bone marrow transplant recipients. Clin. Infect. Dis 1996, 22:778-782.
12. Williamson E.C.M., Millar M.R., Steward C.G., Cornish J.M., Foot A.B.M., Oakhill A., et al. Infections in adults undergoing unrelated donor bone marrow transplantation. Br. J. Haematol 1999, 104:560-568.
13. Roghmann M., Ball K., Erdman D., Lovchik J., Anderson L.J., Edelman R. Active surveillance for respiratory virus infections in adults who have undergone bone marrow and peripheral blood stem cell transplantation. Bone Marrow Transplant 2003, 32:1085-1088.
14. Hassan I.A., Chopra R., Swindell R., Mutton K.J. Respiratory viral infections after bone marrow/peripheral stem-cell transplantation: the Christie hospital experience. Bone Marrow Transplant 2003, 32:73-77.
15. Martino R., Porras R.P., Rabella N., Williams J.V., Ramila E., Margall N., et al. Prospective study of the incidence, clinical features, and outcome of symptomatic upper and lower respiratory tract infections by respiratory viruses in adult recipients of hematopoietic stem cell transplants for hematologic malignancies. Biol. Blood Marrow Transplant 2005, 11:781-796.
16. Dignan F., Alvares C., Riley U., Ethell M., Cunningham D., Treleaven J., et al. Parainfluenza type 3 infection post stem cell transplant: high prevalence but low mortality. J. Hosp. Infect 2006, 63:452-458.
17. Schiffer J.T., Kirby K., Sandmaier B., Storb R., Corey L., Boeckh M. Timing and severity of community acquired respiratory virus infections after myeloablative versus non-myeloablative hematopoietic stem cell transplantation. Haematologica 2009, 94:1101-1108.
18. Ljungman P., Gleaves C.A., Meyers J.D. Respiratory virus infection in immunocompromised patients. Bone Marrow Transplant 1989, 4:35-40.
19. Wendt C.H., Weisdorf D.J., Jordan M.C., Balfour H.H., Hertz M.I. Parainfluenza virus respiratory infection after bone marrow transplantation. N. Engl. J. Med 1992, 326:921-926.
20. Elizaga J., Olavarria E., Apperley J., Goldman J., Ward K. Parainfluenza virus 3 infection after stem cell transplant: relevance to outcome of rapid diagnosis and ribavirin treatment. Clin. Infect. Dis 2001, 32:413-418.
21. Nichols W.G., Gooley T., Boeckh M. Community-acquired respiratory syncytial virus and parainfluenza virus infections after hematopoietic stem cell transplantation: the Fred Hutchinson Cancer Research Center experience. Biol. Blood Marrow Transplant 2001, 7(Suppl.):11S-15S.
22. Ljungman P., Ward K.N., Crooks B.N.A., Parker A., Martino R., Shaw P.J., et al. Respiratory virus infections after stem cell transplantation: a prospective study from the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant 2001, 28:479-484.
23. Crippa F., Holmberg L., Carter R.A., Hooper H., Marr K.A., Bensinger W., et al. Infectious complications after autologous CD34-selected peripheral blood stem cell transplantation. Biol. Blood Marrow Transplant 2002, 8:281-289.
24. Machado C.M., Boas L.S.V., Mendes A.V.A., Santos M.F.M., da Rocha I.F., Sturaro D., et al. Low mortality rates related to respiratory virus infections after bone marrow transplantation. Bone Marrow Transplant 2003, 31:695-700.
25. Raboni S.M., Nogueira M.B., Tsuchiya L.R.V., Takahashi G.A., Pereira L.A., Pasquini R., et al. Respiratory tract viral infections in bone marrow transplant patients. Transplantation 2003, 76:142-146.
26. Peck A.J., Englund J.A., Kuypers J., Guthrie K.A., Corey L., Morrow R., et al. Respiratory virus infection among hematopoietic cell transplant recipients: evidence for asymptomatic parainfluenza virus infection. Blood 2007, 110:1681-1688.
27. Ustun C., Slabý J., Shanley R.M., Vydra J., Smith A.R., Wagner J.E., et al. Human parainfluenza virus infection after hematopoietic stem cell transplantation: risk factors, management, mortality, and changes over time. Biol. Blood Marrow Transplant 2012, 18:1580-1588.
28. Craft A.W., Reid M.M., Gardner P.S. Virus infections in children with acute lymphoblastic leukemia. Arch. Dis. Child 1979, 54:755-759.
29. Mottonen M., Uhari M., Lanning M., Tuokko H. Prospective controlled survey of viral infections in children with acute lymphoblastic leukemia during chemotherapy. Cancer 1995, 75:1712-1717.
30. Srinivasan A., Wang C., Yang J., Inaba H., Shenep J.L., Leung W.H., et al. Parainfluenza virus infections in children with hematologic malignancies. Pediatr. Infect. Dis. J. 2011, 30:855-859.
31. Marcolini J.A., Malik S., Suki D., Whimbey E., Bodey G.P. Respiratory disease due to parainfluenza virus in adult leukemia patients. Eur. J. Clin. Microbiol. Infect. Dis 2003, 22:79-84.
32. Martino R., Ramila E., Rabella N., Munoz J.M., Peyret M., Portos J.M., et al. Respiratory virus infections in adults with hematologic malignancies: a prospective study. Clin. Infect. Dis 2003, 36:1-8.
33. Park S.Y., Baek S., Lee S.O., Choi S.H., Kim Y.S., Woo J.H., et al. Efficacy of oral ribavirin in hematologic disease patients with paramyxovirus infection: analytic strategy using propensity scores. Antimicrob. Agents Chemother 2013, 57:983-989.
34. Chemaly R.F., Ghosh S., Bodey G.P., Rohatgi N., Safdar A., Keating M.J., et al. Respiratory viral infections in adults with hematologic malignancies and human stem cell transplantation recipients: a retrospective study at a major cancer center. Medicine 2006, 85:278-287.
35. Couch R.B., Englund J.A., Whimbey E. Respiratory viral infections in immunocompetent and immunocompromised persons. Am. J. Med 1997, 102:2-9. discussion 25-26.
36. Garrett Nichols W., Corey L., Gooley T., Davis C., Boeckh M. Parainfluenza virus infections after hematopoietic stem cell transplantation: risk factors, response to antiviral therapy, and effect on transplant outcome. Blood 2001, 98:573-578.
37. Versluys A.B., Rossen J.W., van Ewijk B., Schuurman R., Bierings M.B., Boelens J.J. Strong association between respiratory viral infection early after hematopoietic stem cell transplantation and the development of life-threatening acute and chronic alloimmune lung syndromes. Biol. Blood Marrow Transplant 2010, 16:782-791.
38. Au B.K., Au M.A., Chien J.W. Bronchiolitis obliterans syndrome epidemiology after allogeneic hematopoietic cell transplantation. Biol. Blood Marrow Transplant 2011, 17:1072-1078.
39. Ray C.G., Minnich L.L. Efficiency of immunofluorescence for rapid detection of common respiratory viruses. J. Clin. Microbiol 1987, 25:355-357.
40. Osiowy C. Direct detection of respiratory syncytial virus, parainfluenza virus, and adenovirus in clinical respiratory specimens by a multiplex reverse transcription-PCR assay. J. Clin. Microbiol 1998, 36:3149-3154.
41. Fan J., Henrickson K.J., Savatski L.L. Rapid simultaneous diagnosis of infections with respiratory syncytial viruses A and B, influenza viruses A and B, and human parainfluenza virus types 1, 2, and 3 by multiplex quantitative reverse transcription-polymerase chain reaction-enzyme hybridization assay (Hexaplex). Clin. Infect. Dis 1998, 26:1397-1402.
42. Kuypers J., Campbell A.P., Cent A., Corey L., Boeckh M. Comparison of conventional and molecular detection of respiratory viruses in hematopoietic cell transplant recipients. Transpl. Infect. Dis 2009, 11:298-303.
43. Miller W.T., Mickus T.J., Barbosa E., Mullin C., Van Deerlin V.M., Shiley K.T. CT of viral lower respiratory tract infections in adults: comparison among viral organisms and between viral and bacterial infections. AJR Am. J. Roentgenol 2011, 197:1088-1095.
44. Shiley K.T., Van Deerlin V.M., Miller W.T. Chest CT features of community-acquired respiratory viral infections in adult inpatients with lower respiratory tract infections. J. Thorac. Imaging 2010, 25:68-75.
45. Kanne J.P., Godwin J.D., Franquet T., Escuissato D.L., Muller N.L. Viral pneumonia after hematopoietic stem cell transplantation: high-resolution CT findings. J. Thorac. Imaging 2007, 22:292-299.
46. Chen Y.-B., Driscoll J.P., McAfee S.L., Spitzer T.R., Rosenberg E.S., Sanders R., et al. Treatment of parainfluenza 3 infection with DAS181 in a patient after allogeneic stem cell transplantation. Clin. Infect. Dis 2011, 53:e77-e80.
47. Alymova I.V., Taylor G., Takimoto T., Lin T.H., Chand P., Babu Y.S., et al. Efficacy of novel hemagglutinin-neuraminidase inhibitors BCX 2798 and BCX 2855 against human parainfluenza viruses in vitro and in vivo. Antimicrob. Agents Chemother 2004, 48:1495-1502.
48. Guzman-Suarez B.B., Buckley M.W., Gilmore E.T., Vocca E., Moss R., Marty F.M., et al. Clinical potential of DAS181 for treatment of parainfluenza-3 infections in transplant recipients. Transpl. Infect. Dis 2012, 14:427-433.
49. Moscona A., Porotto M., Palmer S., Tai C., Aschenbrenner L., Triana-Baltzer G., et al. A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo. J. Infect. Dis 2010, 202:234-241.
50. Otczyk D.C., Cripps A.W. Mucosal immunization: a realistic alternative. Hum. Vaccin 2010, 6:978-1006.
51. Aliyu Z.Y., Bordner M.A., Henderson D.K., Sloand E.M., Young N.S., Childs R., et al. Low morbidity but prolonged viral shedding characterize parainfluenza virus 3 infections in allogeneic peripheral stem cell transplant recipients. Blood 2004, 104:614A.
52. Gilbert B.E., Knight V. Biochemistry and clinical applications of ribavirin. Antimicrob. Agents Chemother 1986, 30:201-205.
53. McIntosh K., Kurachek S.C., Cairns L.M. Treatment of respiratory viral infection in an immunodeficient infant with ribavirin aerosol. Am. J. Dis. Child 1984, 138:305-308.
54. Sidwell R.W., Khare G.P., Allen L.B., Huffman J.G., Witkowski J.T., Simon L.N., et al. In vitro and in vivo effect of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (ribavirin) on types 1 and 3 parainfulenza virus infections. Chemotherapy 1975, 21:205-220.
55. Seo S., Xie H., Campbell A.P., Kuypers J.M., Leisenring W.M., Englund J.A., et al. Parainfluenza virus lower respiratory tract disease after hematopoietic cell transplant: viral detection in the lung predicts outcome. Clin. Infect. Dis 2014, 58:1357-1368.