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Volumn 46, Issue , 2015, Pages S47-S50

The challenge of Clostridium difficile infection: Overview of clinical manifestations, diagnostic tools and therapeutic options

Author keywords

Antibiotic associated diarrhoea; Clostridium difficile; Colitis; Diagnosis; Therapy

Indexed keywords

ANTIBIOTIC AGENT; ANTITOXIN; BACTERIAL TOXIN; IMMUNOGLOBULIN; METRONIDAZOLE; NITAZOXANIDE; RAMOPLANIN; RIFAXIMIN; TEICOPLANIN; TIGECYCLINE; VANCOMYCIN;

EID: 84949530056     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2015.11.001     Document Type: Article
Times cited : (18)

References (50)
  • 1
    • 0017801430 scopus 로고
    • Antibiotic-associated pseudomembranous colitis due to toxin-producing clostridia
    • J.G. Bartlett, T.W. Chang, M. Gurwith, S.L. Gorbach, and A.B. Onderdonk Antibiotic-associated pseudomembranous colitis due to toxin-producing clostridia N Engl J Med 298 1978 531 534
    • (1978) N Engl J Med , vol.298 , pp. 531-534
    • Bartlett, J.G.1    Chang, T.W.2    Gurwith, M.3    Gorbach, S.L.4    Onderdonk, A.B.5
  • 3
    • 84908178824 scopus 로고    scopus 로고
    • The rise in Clostridium difficile infection incidence among hospitalized adults in the United States: 2001-2010
    • K.R. Reveles, G.C. Lee, N.K. Boyd, and C.R. Frei The rise in Clostridium difficile infection incidence among hospitalized adults in the United States: 2001-2010 Am J Infect Control 42 2014 1028 1032
    • (2014) Am J Infect Control , vol.42 , pp. 1028-1032
    • Reveles, K.R.1    Lee, G.C.2    Boyd, N.K.3    Frei, C.R.4
  • 4
    • 36549073638 scopus 로고    scopus 로고
    • Outcomes of Clostridium difficile-associated disease treated with metronidazole or vancomycin before and after the emergence of NAP1/027
    • J. Pépin, L. Valiquette, S. Gagnon, S. Routhier, and I. Brazeau Outcomes of Clostridium difficile-associated disease treated with metronidazole or vancomycin before and after the emergence of NAP1/027 Am J Gastroenterol 102 2007 2781 2788
    • (2007) Am J Gastroenterol , vol.102 , pp. 2781-2788
    • Pépin, J.1    Valiquette, L.2    Gagnon, S.3    Routhier, S.4    Brazeau, I.5
  • 5
    • 0033604532 scopus 로고    scopus 로고
    • Epidemics of diarrhea caused by a clindamycin-resistant strain of Clostridium difficile in four hospitals
    • S. Johnson, M.H. Samore, K.A. Farrow, G.E. Killgore, F.C. Tenover, D. Lyras, and et al. Epidemics of diarrhea caused by a clindamycin-resistant strain of Clostridium difficile in four hospitals N Engl J Med 341 1999 1645 1651
    • (1999) N Engl J Med , vol.341 , pp. 1645-1651
    • Johnson, S.1    Samore, M.H.2    Farrow, K.A.3    Killgore, G.E.4    Tenover, F.C.5    Lyras, D.6
  • 6
    • 27444437759 scopus 로고    scopus 로고
    • Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea: A cohort study during an epidemic in Quebec
    • J. Pépin, N. Saheb, M.A. Coulombe, M.E. Alary, M.P. Corriveau, S. Authier, and et al. Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea: a cohort study during an epidemic in Quebec Clin Infect Dis 41 2005 1254 1260
    • (2005) Clin Infect Dis , vol.41 , pp. 1254-1260
    • Pépin, J.1    Saheb, N.2    Coulombe, M.A.3    Alary, M.E.4    Corriveau, M.P.5    Authier, S.6
  • 7
    • 0017609086 scopus 로고
    • Diarrhea associated with clindamycin and ampicillin therapy: Preliminary results of a cooperative study
    • M.J. Gurwith, H.R. Rabin, and K. Love Diarrhea associated with clindamycin and ampicillin therapy: preliminary results of a cooperative study J Infect Dis 135 Suppl 1977 S104 S110
    • (1977) J Infect Dis , vol.135 , pp. S104-S110
    • Gurwith, M.J.1    Rabin, H.R.2    Love, K.3
  • 10
    • 84855422347 scopus 로고    scopus 로고
    • The epidemiology of community-acquired Clostridium difficile infection: A population-based study
    • Erratum in: Am J Gastroenterol 2012;107:150
    • S. Khanna, D.S. Pardi, S.L. Aronson, P.P. Kammer, R. Orenstein, J.L. St Sauver, and et al. The epidemiology of community-acquired Clostridium difficile infection: a population-based study Am J Gastroenterol 107 2012 89 95 Erratum in: Am J Gastroenterol 2012;107:150
    • (2012) Am J Gastroenterol , vol.107 , pp. 89-95
    • Khanna, S.1    Pardi, D.S.2    Aronson, S.L.3    Kammer, P.P.4    Orenstein, R.5    St Sauver, J.L.6
  • 11
    • 84889582557 scopus 로고    scopus 로고
    • Health care-associated infections: A meta-analysis of costs and financial impact on the US health care system
    • E. Zimlichman, D. Henderson, O. Tamir, C. Franz, P. Song, C.K. Yamin, and et al. Health care-associated infections: a meta-analysis of costs and financial impact on the US health care system JAMA Intern Med 173 2013 2039 2046
    • (2013) JAMA Intern Med , vol.173 , pp. 2039-2046
    • Zimlichman, E.1    Henderson, D.2    Tamir, O.3    Franz, C.4    Song, P.5    Yamin, C.K.6
  • 12
    • 55249105923 scopus 로고    scopus 로고
    • Clostridium difficile-more difficult than ever
    • C.P. Kelly, and J.T. LaMont Clostridium difficile-more difficult than ever N Engl J Med 359 2008 1932 1940
    • (2008) N Engl J Med , vol.359 , pp. 1932-1940
    • Kelly, C.P.1    LaMont, J.T.2
  • 13
    • 84921767408 scopus 로고    scopus 로고
    • Diagnosis and treatment of Clostridium difficile in adults: A systematic review
    • N. Bagdasarian, K. Rao, and P.N. Malani Diagnosis and treatment of Clostridium difficile in adults: a systematic review JAMA 313 2015 398 408
    • (2015) JAMA , vol.313 , pp. 398-408
    • Bagdasarian, N.1    Rao, K.2    Malani, P.N.3
  • 14
    • 0034525733 scopus 로고    scopus 로고
    • Effects of Clostridium difficile toxins on epithelial cell barrier
    • C. Pothoulakis Effects of Clostridium difficile toxins on epithelial cell barrier Ann N Y Acad Sci 915 2000 347 356
    • (2000) Ann N y Acad Sci , vol.915 , pp. 347-356
    • Pothoulakis, C.1
  • 15
    • 0036241355 scopus 로고    scopus 로고
    • Changes in predominant bacterial populations in human faeces with age and with Clostridium difficile infection
    • M.J. Hopkins, and G.T. Macfarlane Changes in predominant bacterial populations in human faeces with age and with Clostridium difficile infection J Med Microbiol 51 2002 448 454
    • (2002) J Med Microbiol , vol.51 , pp. 448-454
    • Hopkins, M.J.1    Macfarlane, G.T.2
  • 16
    • 84903950312 scopus 로고    scopus 로고
    • Prevalence and risk factors for asymptomatic Clostridium difficile carriage
    • F. Alasmari, S. Seile, T. Hink, C. Burnham, and E. Dubberke Prevalence and risk factors for asymptomatic Clostridium difficile carriage Clin Infect Dis 59 2014 216 222
    • (2014) Clin Infect Dis , vol.59 , pp. 216-222
    • Alasmari, F.1    Seile, S.2    Hink, T.3    Burnham, C.4    Dubberke, E.5
  • 17
    • 0034628426 scopus 로고    scopus 로고
    • Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A
    • L. Kyne, M. Warny, A. Qamar, and C.P. Kelly Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A N Engl J Med 34 2000 390 397
    • (2000) N Engl J Med , vol.34 , pp. 390-397
    • Kyne, L.1    Warny, M.2    Qamar, A.3    Kelly, C.P.4
  • 18
  • 19
    • 34848846245 scopus 로고    scopus 로고
    • Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents
    • M.M. Riggs, A.K. Sethi, T.F. Zabarsky, E.C. Eckstein, R.L. Jump, and C.J. Donskey Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents Clin Infect Dis 45 2007 992 998
    • (2007) Clin Infect Dis , vol.45 , pp. 992-998
    • Riggs, M.M.1    Sethi, A.K.2    Zabarsky, T.F.3    Eckstein, E.C.4    Jump, R.L.5    Donskey, C.J.6
  • 20
    • 0032574193 scopus 로고    scopus 로고
    • Primary symptomless colonisation by Clostridium difficile and decreased risk of subsequent diarrhoea
    • J.K. Shim, S. Johnson, M.H. Samore, D.Z. Blizz, and D.N. Gerding Primary symptomless colonisation by Clostridium difficile and decreased risk of subsequent diarrhoea Lancet 351 1998 633 636
    • (1998) Lancet , vol.351 , pp. 633-636
    • Shim, J.K.1    Johnson, S.2    Samore, M.H.3    Blizz, D.Z.4    Gerding, D.N.5
  • 21
    • 0037097647 scopus 로고    scopus 로고
    • Conditions associated with leukocytosis in a tertiary care hospital, with particular attention to the role of infection caused by Clostridium difficile
    • A. Wanahita, E.A. Goldsmith, and D.M. Musher Conditions associated with leukocytosis in a tertiary care hospital, with particular attention to the role of infection caused by Clostridium difficile Clin Infect Dis 34 2002 1585 1592
    • (2002) Clin Infect Dis , vol.34 , pp. 1585-1592
    • Wanahita, A.1    Goldsmith, E.A.2    Musher, D.M.3
  • 22
    • 0019979693 scopus 로고
    • Pseudomembranous colitis: Pathogenesis and therapy
    • F.J. Tedesco Pseudomembranous colitis: pathogenesis and therapy Med Clin North Am 66 1982 655 664
    • (1982) Med Clin North Am , vol.66 , pp. 655-664
    • Tedesco, F.J.1
  • 23
    • 84887259304 scopus 로고    scopus 로고
    • European Society of Clinical Microbiology and Infectious Diseases: Update of the treatment guidance document for Clostridium difficile infection
    • S.B. Debast, M.P. Bauer, and E.J. Kuijper European Society of Clinical Microbiology and Infectious Diseases: update of the treatment guidance document for Clostridium difficile infection Clin Microbiol Infect 20 Suppl 2 2014 1 26
    • (2014) Clin Microbiol Infect , vol.20 , pp. 1-26
    • Debast, S.B.1    Bauer, M.P.2    Kuijper, E.J.3
  • 24
    • 84905057299 scopus 로고    scopus 로고
    • Vancomycin, metronidazole, or tolevamer for Clostridium difficile infection: Results from two multinational, randomized, controlled trials
    • S. Johnson, T.J. Louie, D.N. Gerding, O.A. Cornely, S. Chasan-Taber, D. Fitts, and et al. Vancomycin, metronidazole, or tolevamer for Clostridium difficile infection: results from two multinational, randomized, controlled trials Clin Infect Dis 59 2014 345 354
    • (2014) Clin Infect Dis , vol.59 , pp. 345-354
    • Johnson, S.1    Louie, T.J.2    Gerding, D.N.3    Cornely, O.A.4    Chasan-Taber, S.5    Fitts, D.6
  • 27
    • 0031016896 scopus 로고    scopus 로고
    • Recurrent Clostridium difficile diarrhea: Characteristics of and risk factors for patients enrolled in a prospective, randomized, double-blinded trial
    • R. Fekety, L.V. McFarland, C.M. Surawicz, R.N. Greenberg, G.W. Elmer, and M.E. Mulligan Recurrent Clostridium difficile diarrhea: characteristics of and risk factors for patients enrolled in a prospective, randomized, double-blinded trial Clin Infect Dis 24 1997 324 333
    • (1997) Clin Infect Dis , vol.24 , pp. 324-333
    • Fekety, R.1    McFarland, L.V.2    Surawicz, C.M.3    Greenberg, R.N.4    Elmer, G.W.5    Mulligan, M.E.6
  • 28
    • 0036311186 scopus 로고    scopus 로고
    • Breaking the cycle: Treatment strategies for 163 cases of recurrent Clostridium difficile disease
    • L.V. McFarland, G.W. Elmer, and C.M. Surawicz Breaking the cycle: treatment strategies for 163 cases of recurrent Clostridium difficile disease Am J Gastroenterol 97 2002 1769 1775
    • (2002) Am J Gastroenterol , vol.97 , pp. 1769-1775
    • McFarland, L.V.1    Elmer, G.W.2    Surawicz, C.M.3
  • 29
    • 65449165706 scopus 로고    scopus 로고
    • Treatment of Clostridium difficile-associated disease
    • D.A. Leffler, and J.T. Lamont Treatment of Clostridium difficile-associated disease Gastroenterology 136 2009 1899 1912
    • (2009) Gastroenterology , vol.136 , pp. 1899-1912
    • Leffler, D.A.1    Lamont, J.T.2
  • 30
    • 62949146399 scopus 로고    scopus 로고
    • Prospective derivation and validation of a clinical prediction rule for recurrent Clostridium difficile infection
    • M.Y. Hu, K. Katchar, L. Kyne, S. Maroo, S. Tummala, V. Dreisbach, and et al. Prospective derivation and validation of a clinical prediction rule for recurrent Clostridium difficile infection Gastroenterology 136 2009 1206 1214
    • (2009) Gastroenterology , vol.136 , pp. 1206-1214
    • Hu, M.Y.1    Katchar, K.2    Kyne, L.3    Maroo, S.4    Tummala, S.5    Dreisbach, V.6
  • 31
    • 84863676557 scopus 로고    scopus 로고
    • Treatment of first recurrence of Clostridium difficile infection: Fidaxomicin versus vancomycin
    • O.A. Cornely, M.A. Miller, T.J. Louie, D.W. Crook, and S.L. Gorbach Treatment of first recurrence of Clostridium difficile infection: fidaxomicin versus vancomycin Clin Infect Dis 55 Suppl 2 2012 S154 S161
    • (2012) Clin Infect Dis , vol.55 , pp. S154-S161
    • Cornely, O.A.1    Miller, M.A.2    Louie, T.J.3    Crook, D.W.4    Gorbach, S.L.5
  • 32
    • 33846436449 scopus 로고    scopus 로고
    • Impact of emergency colectomy on survival of patients with fulminant Clostridium difficile colitis during an epidemic caused by a hypervirulent strain
    • F. Lamontagne, A.C. Labbé, O. Haeck, O. Lesur, M. Lalancette, C. Patino, and et al. Impact of emergency colectomy on survival of patients with fulminant Clostridium difficile colitis during an epidemic caused by a hypervirulent strain Ann Surg 245 2007 267 272
    • (2007) Ann Surg , vol.245 , pp. 267-272
    • Lamontagne, F.1    Labbé, A.C.2    Haeck, O.3    Lesur, O.4    Lalancette, M.5    Patino, C.6
  • 33
    • 36549073638 scopus 로고    scopus 로고
    • Outcomes of Clostridium difficile-associated disease treated with metronidazole or vancomycin before and after the emergence of NAP1/027
    • J. Pépin, L. Valiquette, S. Gagnon, S. Routhier, and I. Brazeau Outcomes of Clostridium difficile-associated disease treated with metronidazole or vancomycin before and after the emergence of NAP1/027 Am J Gastroenterol 102 2007 2781 2788
    • (2007) Am J Gastroenterol , vol.102 , pp. 2781-2788
    • Pépin, J.1    Valiquette, L.2    Gagnon, S.3    Routhier, S.4    Brazeau, I.5
  • 34
    • 77951026738 scopus 로고    scopus 로고
    • Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA)
    • S.H. Cohen, D.N. Gerding, S. Johnson, C.P. Kelly, V.G. Loo, L.C. McDonald, and et al. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA) Infect Control Hosp Epidemiol 31 2010 431 455
    • (2010) Infect Control Hosp Epidemiol , vol.31 , pp. 431-455
    • Cohen, S.H.1    Gerding, D.N.2    Johnson, S.3    Kelly, C.P.4    Loo, V.G.5    McDonald, L.C.6
  • 36
    • 84859007390 scopus 로고    scopus 로고
    • Fidaxomicin versus vancomycin for infection with Clostridium difficile in Europe, Canada, and the USA: A double-blind, non-inferiority, randomised controlled trial
    • O.A. Cornely, D.W. Crook, R. Esposito, A. Poirier, M.S. Somero, K. Weiss, and et al. Fidaxomicin versus vancomycin for infection with Clostridium difficile in Europe, Canada, and the USA: a double-blind, non-inferiority, randomised controlled trial Lancet Infect Dis 12 2012 281 289
    • (2012) Lancet Infect Dis , vol.12 , pp. 281-289
    • Cornely, O.A.1    Crook, D.W.2    Esposito, R.3    Poirier, A.4    Somero, M.S.5    Weiss, K.6
  • 37
    • 0037105769 scopus 로고    scopus 로고
    • Adjunctive intracolonic vancomycin for severe Clostridium difficile colitis: Case series and review of the literature
    • A. Apisarnthanarak, B. Razavi, and L.M. Mundy Adjunctive intracolonic vancomycin for severe Clostridium difficile colitis: case series and review of the literature Clin Infect Dis 35 2002 690 696
    • (2002) Clin Infect Dis , vol.35 , pp. 690-696
    • Apisarnthanarak, A.1    Razavi, B.2    Mundy, L.M.3
  • 38
    • 0036192008 scopus 로고    scopus 로고
    • Fulminant Clostridium difficile: An underappreciated and increasing cause of death and complications
    • R.M. Dallal, B.G. Harbrecht, A.J. Boujoukas, C.A. Sirio, L.M. Farkas, K.K. Lee, and et al. Fulminant Clostridium difficile: an underappreciated and increasing cause of death and complications Ann Surg 235 2002 363 372
    • (2002) Ann Surg , vol.235 , pp. 363-372
    • Dallal, R.M.1    Harbrecht, B.G.2    Boujoukas, A.J.3    Sirio, C.A.4    Farkas, L.M.5    Lee, K.K.6
  • 39
    • 80052277400 scopus 로고    scopus 로고
    • Diverting loop ileostomy and colonic lavage: An alternative to total abdominal colectomy for the treatment of severe, complicated Clostridium difficile associated disease
    • M.D. Neal, J.C. Alverdy, D.E. Hall, R.L. Simmons, and B.S. Zuckerbraun Diverting loop ileostomy and colonic lavage: an alternative to total abdominal colectomy for the treatment of severe, complicated Clostridium difficile associated disease Ann Surg 254 2011 423 427
    • (2011) Ann Surg , vol.254 , pp. 423-427
    • Neal, M.D.1    Alverdy, J.C.2    Hall, D.E.3    Simmons, R.L.4    Zuckerbraun, B.S.5
  • 40
    • 84937028983 scopus 로고    scopus 로고
    • Clostridium difficile infection
    • D.A. Leffler, and J.T. Lamont Clostridium difficile infection N Engl J Med 373 2015 287 288
    • (2015) N Engl J Med , vol.373 , pp. 287-288
    • Leffler, D.A.1    Lamont, J.T.2
  • 41
    • 84875952542 scopus 로고    scopus 로고
    • Fecal microbiota transplantation for Clostridium difficile infection: Systematic review and meta-analysis
    • Z. Kassam, C.H. Lee, Y. Yuan, and R.H. Hunt Fecal microbiota transplantation for Clostridium difficile infection: systematic review and meta-analysis Am J Gastroenterol 108 2013 500 508
    • (2013) Am J Gastroenterol , vol.108 , pp. 500-508
    • Kassam, Z.1    Lee, C.H.2    Yuan, Y.3    Hunt, R.H.4
  • 43
    • 84928009180 scopus 로고    scopus 로고
    • Intestinal microbiota transplantation, a simple and effective treatment for severe and refractory Clostridium difficile infection
    • H. Zainah, M. Hassan, L. Shiekh-Sroujieh, S. Hassan, G. Alangaden, and M. Ramesh Intestinal microbiota transplantation, a simple and effective treatment for severe and refractory Clostridium difficile infection Dig Dis Sci 60 2015 181 185
    • (2015) Dig Dis Sci , vol.60 , pp. 181-185
    • Zainah, H.1    Hassan, M.2    Shiekh-Sroujieh, L.3    Hassan, S.4    Alangaden, G.5    Ramesh, M.6
  • 44
    • 84903894091 scopus 로고    scopus 로고
    • Fecal microbiota transplant for treatment of Clostridium difficile infection in immuno-compromised patients
    • C.R. Kelly, C. Ihunnah, M. Fischer, A. Khoruts, C. Surawicz, A. Afzali, and et al. Fecal microbiota transplant for treatment of Clostridium difficile infection in immuno-compromised patients Am J Gastroenterol 109 2014 1065 1071
    • (2014) Am J Gastroenterol , vol.109 , pp. 1065-1071
    • Kelly, C.R.1    Ihunnah, C.2    Fischer, M.3    Khoruts, A.4    Surawicz, C.5    Afzali, A.6
  • 45
    • 0018844685 scopus 로고
    • Binding of Clostridium difficile cytotoxin and vancomycin by anion-exchange resins
    • N.S. Taylor, and J.G. Bartlett Binding of Clostridium difficile cytotoxin and vancomycin by anion-exchange resins J Infect Dis 141 1980 92 97
    • (1980) J Infect Dis , vol.141 , pp. 92-97
    • Taylor, N.S.1    Bartlett, J.G.2
  • 47
    • 0018075282 scopus 로고
    • Treatment of antibiotic-associated pseudomembranous colitis with cholestyramine resin
    • E.W. Kreutzer, and F.D. Milligan Treatment of antibiotic-associated pseudomembranous colitis with cholestyramine resin Johns Hopkins Med J 143 1978 67 72
    • (1978) Johns Hopkins Med J , vol.143 , pp. 67-72
    • Kreutzer, E.W.1    Milligan, F.D.2
  • 48
    • 0020065163 scopus 로고
    • Treatment of recurrent antibiotic-associated pseudomembranous colitis
    • F.J. Tedesco Treatment of recurrent antibiotic-associated pseudomembranous colitis Am J Gastroenterol 77 1982 220 221
    • (1982) Am J Gastroenterol , vol.77 , pp. 220-221
    • Tedesco, F.J.1
  • 49
    • 33847150865 scopus 로고    scopus 로고
    • Clinical outcomes of intravenous immune globulin in severe Clostridium difficile-associated diarrhea
    • P. Juang, S.J. Skledar, N.K. Zgheib, D.L. Paterson, E.N. Vergis, W.D. Shannon, and et al. Clinical outcomes of intravenous immune globulin in severe Clostridium difficile-associated diarrhea Am J Infect Control 35 2007 131 137
    • (2007) Am J Infect Control , vol.35 , pp. 131-137
    • Juang, P.1    Skledar, S.J.2    Zgheib, N.K.3    Paterson, D.L.4    Vergis, E.N.5    Shannon, W.D.6
  • 50
    • 70349895519 scopus 로고    scopus 로고
    • Hospital and societal costs of antimicrobial-resistant infections in a Chicago teaching hospital: Implications for antibiotic stewardship
    • R.R. Roberts, B. Hota, I. Ahmad, R.D.2nd Scott, S.D. Foster, F. Abbasi, and et al. Hospital and societal costs of antimicrobial-resistant infections in a Chicago teaching hospital: implications for antibiotic stewardship Clin Infect Dis 49 2009 1175 1184
    • (2009) Clin Infect Dis , vol.49 , pp. 1175-1184
    • Roberts, R.R.1    Hota, B.2    Ahmad, I.3    Scott, R.D.4    Foster, S.D.5    Abbasi, F.6


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