Personalized medicine beyond genomics: alternative futures in big data—proteomics, environtome and the social proteome

Journal of Neural Transmission

Volumn 124, Issue 1, 2017, Pages 25-32

  Özdemir, Vural ^a,b   Dove, Edward S ^c   Gürsoy, Ulvi K ^d   Şardaş, Semra ^e   Yıldırım, Arif ^f   Yılmaz, Şenay Görücü ^a   Omer Barlas I ^g   Güngör, Kıvanç ^a   Mete, Alper ^a   Srivastava, Sanjeeva ^h  

^a GAZIANTEP UNIVERSITY   (Turkey)

^b AMRITA UNIVERSITY   (India)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d UNIVERSITY OF TURKU   (Finland)

^e MARMARA UNIVERSITY   (Turkey)

^f NAMIK KEMAL UNIVERSITY   (Turkey)

^g MERSIN UNIVERSITY   (Turkey)

^h INDIAN INSTITUTE OF TECHNOLOGY BOMBAY   (India)

Author keywords

Big data; Futures studies; Innovation management systems; Precision medicine; Proteomics; Technology foresight

Indexed keywords

BIOLOGICAL MARKER; PROTEOME;

ENVIRONMENTAL TEMPERATURE; ETHICIST; GENOMICS; GOVERNMENT; HUMAN; MARKET; MICROBIOME; PERSONALIZED MEDICINE; POLICY; PRIORITY JOURNAL; PROTEOMICS; PSYCHIATRY; REIMBURSEMENT; REVIEW; SCIENTIST; SOCIAL NORM; WEATHER; DEVICES; MENTAL DISEASE; METABOLISM; PROCEDURES;

HUMANS; MENTAL DISORDERS; PRECISION MEDICINE; PROTEOME; PROTEOMICS; PSYCHIATRY;

EID: 84949505812     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-015-1489-y     Document Type: Review

References (41)

1. Al Awam K, Haußleiter IS, Dudley E, Donev R, Brüne M, Juckel G, Thome J (2015) Multiplatform metabolome and proteome profiling identifies serum metabolite and protein signatures as prospective biomarkers for schizophrenia. J Neural Transm 122(Suppl 1):S111–S122
2. Anderson NG, Matheson A, Anderson NL (2001) Back to the future: the human protein index (HPI) and the agenda for post-proteomic biology. Proteomics 1:3–12
3. Bourdieu P, Wacquant L (1992) Invitation to reflexive sociology. Chicago University Press, Chicago
4. Calimlioglu B, Karagoz K, Sevimoglu T, Kilic E, Gov E, Arga KY (2015) Tissue-specific molecular biomarker signatures of type 2 diabetes: an integrative analysis of transcriptomics and protein–protein interaction data. OMICS 19(9):563–573
5. Collingridge D (1980) The social control of technology. St. Martin’s Press, New York
6. De Vries R (2004) How can we help? From ‘sociology in’ bioethics to ‘sociology of’ bioethics. J Law Med Ethics 32:279–292
7. Diderot D (1988) Supplément au voyage de Bougainville. Jimack P (trans). Grant & Cutler, London
8. Dimitrakopoulou K, Dimitrakopoulos GN, Sgarbas KN, Bezerianos A (2014) Tamoxifen integromics and personalized medicine: dynamic modular transformations underpinning response to tamoxifen in breast cancer treatment. OMICS 2014 18:15–33
9. Domschke K, Müller DJ, Serretti A (2015) Personalized therapies in psychiatry: promises, pitfalls and perspectives. J Neural Transm (Vienna) 122(1):1–3
10. Dove ES, Özdemir V (2014) The epiknowledge of socially responsible innovation. EMBO Rep 15:462–463
11. Dove ES, Özdemir V (2015) What role for law, human rights, and bioethics in an age of Big Data, consortia science, and consortia ethics? The importance of trustworthiness. Laws 4(3):515–540. http://www.mdpi.com/2075-471X/4/3/515. Accessed 18 Nov 2015
12. Ghidoni R, Paterlini A, Benussi L (2013) Translational proteomics in Alzheimer’s disease and related disorders. Clin Biochem 46(6):480–486
13. Haffeld J, Siem H (2013) The post-2015 agenda: complexity theory-based governance of the global health system in the era of postgenomics and personalized medicine. Curr Pharmacogenomics Person Med 11:309–311
14. Higdon R, Earl RK, Stanberry L, Hudac CM, Montague E, Stewart E, Janko I, Choiniere J, Broomall W, Kolker N, Bernier RA, Kolker E (2015) The promise of multi-omics and clinical data integration to identify and target personalized healthcare approaches in autism spectrum disorders. OMICS 19(4):197–208
15. Hogan JM, Higdon R, Kolker E (2006) Experimental standards for high-throughput proteomics. OMICS 10(2):152–157
16. Jain A, Rakhi NK, Bagler G (2015) Analysis of food pairing in regional cuisines of India. PLoS ONE 10(10):e0139539
17. Jehmlich N, Dinh KH, Gesell-Salazar M, Hammer E, Steil L, Dhople VM, Schurmann C, Holtfreter B, Kocher T, Völker U (2013) Quantitative analysis of the intra- and inter-subject variability of the whole salivary proteome. J Periodontal Res 48(3):392–403
18. Kasthuri RS, Verneris MR, Ibrahim HN, Jilma B, Nelsestuen GL (2006) Studying multiple protein profiles over time to assess biomarker validity. Expert Rev Proteomics 3(4):455–464
19. López JL, Lunau J (2012) ELSIfication in Canada: legal modes of reasoning. Sci Cult 21:77–99
20. Ma Y, Sun Z, de Matos R, Zhang J, Odunsi K, Lin B (2014) Towards an animal model of ovarian cancer: cataloging chicken blood proteins using combinatorial peptide ligand libraries coupled with shotgun proteomic analysis for translational research. OMICS 18(5):280–297
21. McCarty MF, Barroso-Aranda J, Contreras F (2009) Regular thermal therapy may promote insulin sensitivity while boosting expression of endothelial nitric oxide synthase—effects comparable to those of exercise training. Med Hypotheses 73(1):103–105
22. McNally R (2005) Sociomics! Using the IssueCrawler to map, monitor and engage with the global proteomics research network. Proteomics 5(12):3010–3016
23. Mehta SM, Banerjee SM, Chowdhary AS (2015) Postgenomics biomarkers for rabies—the next decade of proteomics. OMICS 19(2):67–79
24. Miles I (2010) The development of technology foresight: a review. Technol Forecast Soc Chang 77(9):1448–1456
25. Ostrom E (1990) Governing the commons: the evolution of institutions for collective action. Cambridge University Press, Cambridge
26. Ostrom E (1999) Coping with tragedies of the commons. Annu Rev Polit Sci 2:493–535
27. Özdemir V (2014) Personalized medicine across disciplines and without borders. Vural Özdemir speaks to Hannah Wilson, Commissioning Editor. Per Med 11(7):687–691. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481090/. Accessed 18 Nov 2015
28. Ozdemir V, Endrenyi L, Aynacıoğlu S, Bragazzi NL, Dandara C, Dove ES et al (2014) Bernard Lerer: recipient of the 2014 inaugural Werner Kalow responsible innovation prize in global omics and personalized medicine (Pacific Rim Association for clinical pharmacogenetics). OMICS 18(4):211–221
29. Özdemir V, Faris J, Srivastava S (2015a) Crowdfunding 2.0: the next generation philanthropy. A new approach for philanthropists and citizens to co-fund disruptive innovation in global health. EMBO Rep 16(3):267–271
30. Özdemir V, Kılıç H, Yıldırım A et al (2015b) A code of ethics for ethicists: what would Pierre Bourdieu say? “Do not misuse social capital in the age of consortia ethics”. Am J Bioethics 15(5):64–67
31. Patel S (2014) Role of proteomics in biomarker discovery: prognosis and diagnosis of neuropsychiatric disorders. Adv Protein Chem Struct Biol 94:39–75
32. Pavlidis C, Lanara Z, Balasopoulou A, Nebel JC, Katsila T, Patrinos GP (2015) Meta-analysis of genes in commercially available nutrigenomic tests denotes lack of association with dietary intake and nutrient-related pathologies. OMICS 19(9):512–520
33. Petersen A (2013) From bioethics to a sociology of bio-knowledge. Soc Sci Med 98:264–270
34. Ravetz JR (1971) Scientific knowledge and its social problems. Clarendon Press, Oxford
35. Reddy PJ, Ray S, Srivastava S (2015) The quest of the human proteome and the missing proteins: digging deeper. OMICS 19(5):276–282
36. Sclove RE (1989) From alchemy to atomic war: Frederick Soddy’s “Technology Assessment” of Atomic Energy, 1900–1915. Sci Technol Human Values 14(2):163–194
37. Sokolowska I, Ngounou Wetie AG, Wormwood K, Thome J, Darie CC, Woods AG (2015) The potential of biomarkers in psychiatry: focus on proteomics. J Neural Transm (Vienna) 122(Suppl 1):S9–S18
38. Taleb NN (2010) The black swan: the impact of the highly improbable, 2nd edn. Random House, New York
39. Thoreau F, Delvenne P (2012) Have STS fallen into a political void? Depoliticisation and engagement in the case of nanotechnologies. Politica Sociedade 11:205–226
40. Wood SL, Knowles MA, Thompson D, Selby PJ, Banks RE (2013) Proteomic studies of urinary biomarkers for prostate, bladder and kidney cancers. Nat Rev Urol 10(4):206–218
41. Zhao F, Chen Y, Ge S, Yu X, Shao S, Black M, Wang Y, Zhang J, Song M, Wang W (2014) A quantitative analysis of the mass media coverage of genomics medicine in china: a call for science journalism in the developing world. OMICS 18(4):222–230