A novel antagonist of CXCR4 prevents bone marrow-derived mesenchymal stem cell-mediated osteosarcoma and hepatocellular carcinoma cell migration and invasion

Cancer Letters

Volumn 370, Issue 1, 2016, Pages 100-107

  Fontanella, Raffaela ^a   Pelagalli, Alessandra ^a,b   Nardelli, Anna ^a   D'Alterio, Crescenzo ^c   Ieranò, Caterina ^c   Cerchia, Laura ^d   Lucarelli, Enrico ^e   Scala, Stefania ^c   Zannetti, Antonella ^a  

^a CNR   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c NATIONAL CANCER INSTITUTE   (Italy)

^d CNR   (Italy)

^e RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

Author keywords

Bone marrow derived mesenchymal stem cells (BM MSCs); Chemokine receptor type 4 (CXCR4); Novel CXCR4 inhibitor; Tumor invasion

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTAGONIST; MITOGEN ACTIVATED PROTEIN KINASE; PEPTIDE R; PLERIXAFOR; PROTEIN KINASE B; UNCLASSIFIED DRUG; CXCR4 PROTEIN, HUMAN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CANCER GROWTH; CARCINOGENESIS; CELL FUNCTION; CELL INTERACTION; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CARCINOMA; METASTASIS POTENTIAL; MIGRATION INHIBITION; OSTEOSARCOMA; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SNU 398 CELL LINE; U2OS CELL LINE; ANTAGONISTS AND INHIBITORS; BONE NEOPLASMS; CARCINOMA, HEPATOCELLULAR; CELL MOTION; EPITHELIAL MESENCHYMAL TRANSITION; LIVER NEOPLASMS; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE; TUMOR INVASION; WOUND HEALING;

BONE NEOPLASMS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL MOVEMENT; EPITHELIAL-MESENCHYMAL TRANSITION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; LIVER NEOPLASMS; MESENCHYMAL STROMAL CELLS; NEOPLASM INVASIVENESS; OSTEOSARCOMA; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, CXCR4; WOUND HEALING;

EID: 84949455030     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2015.10.018     Document Type: Article

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