Chronic cigarette smoking impairs erectile function through increased oxidative stress and apoptosis, decreased nNOS, endothelial and smooth muscle contents in a rat model

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Huang, Yun Ching ^a,b   Chin, Chih Chien ^a   Chen, Chih Shou ^a   Shindel, Alan W ^c   Ho, Dong Ru ^a   Lin, Ching Shwun ^d   Shi, Chung Sheng ^b  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIGARETTE SMOKE; NEURONAL NITRIC OXIDE SYNTHASE; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; ELECTROSTIMULATION; ENDOTHELIUM; ERECTILE DYSFUNCTION; IN VIVO STUDY; INTRACAVERNOUS PRESSURE; MALE; MEAN ARTERIAL PRESSURE; MEDICAL PARAMETERS; NERVE STIMULATION; NONHUMAN; OXIDATIVE STRESS; PENIS ERECTION; PILOT STUDY; RAT; SMOKING; SMOOTH MUSCLE; TESTOSTERONE BLOOD LEVEL; URINALYSIS; ANIMAL; BLOOD; BODY WEIGHT; DISEASE MODEL; ENZYMOLOGY; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; TUNEL ASSAY; URINE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BODY WEIGHT; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; ENDOTHELIUM; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MALE; MUSCLE, SMOOTH; NITRIC OXIDE SYNTHASE TYPE I; OXIDATIVE STRESS; PENILE ERECTION; RATS, SPRAGUE-DAWLEY; SMOKING; TESTOSTERONE;

EID: 84949442327     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0140728     Document Type: Article

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