An antimicrobial peptide essential for bacterial survival in the nitrogen-fixing symbiosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 49, 2015, Pages 15238-15243

  Kim, Minsoo ^a   Chen, Yuhui ^b   Xi, Jiejun ^c   Waters, Christopher ^a   Chen, Rujin ^b   Wang, Dong ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b PLANT BIOLOGY DIVISION   (United States)

^c NORTHWEST A F UNIVERSITY   (China)

Author keywords

Legume; Medicago truncatula; NCR antimicrobial peptides; Nitrogen fixing symbiosis; Sinorhizobium meliloti

Indexed keywords

LEGHEMOGLOBIN; POLYPEPTIDE ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; PEPTIDE;

ARTICLE; BACTERIAL GENE; BACTERIAL OUTER MEMBRANE; BACTERIAL SURVIVAL; BACTERIUM MUTANT; BARREL MEDIC; CONTROLLED STUDY; DIFFERENTIATION; DNF4 GENE; GENE EXPRESSION PROFILING; HOST CELL; LINKAGE ANALYSIS; NITROGEN FIXATION; NITROGEN FIXING SYMBIOSIS; NONHUMAN; PHENOTYPE; PLANT GENE; PLANT GROWTH; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SINORHIZOBIUM MELILOTI; SYMBIOSIS; TRANSGENIC PLANT; PHYSIOLOGY; RHIZOBIUM;

ANTI-INFECTIVE AGENTS; NITROGEN FIXATION; PEPTIDES; RHIZOBIUM; SYMBIOSIS;

EID: 84949309774     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1500123112     Document Type: Article

References (29)

1. Vasse J, de Billy F, Camut S, Truchet G (1990) Correlation between ultrastructural differentiation of bacteroids and nitrogen fixation in alfalfa nodules. J Bacteriol 172(8):4295-4306.
2. Gavrin A, et al. (2014) Adjustment of host cells for accommodation of symbiotic bacteria: Vacuole defunctionalization, HOPS suppression, and TIP1g retargeting in Medicago. Plant Cell 26(9):3809-3822.
3. Cebolla A, et al. (1999) The mitotic inhibitor ccs52 is required for endoreduplication and ploidy-dependent cell enlargement in plants. EMBO J 18(16):4476-4484.
4. Kondorosi E, Kondorosi A (2004) Endoreduplication and activation of the anaphase-promoting complex during symbiotic cell development. FEBS Lett 567(1):152-157.
5. Van de Velde W, et al. (2010) Plant peptides govern terminal differentiation of bacteria in symbiosis. Science 327(5969):1122-1126.
6. Wang D, et al. (2010) A nodule-specific protein secretory pathway required for nitrogen-fixing symbiosis. Science 327(5969):1126-1129.
7. Fedorova M, et al. (2002) Genome-wide identification of nodule-specific transcripts in the model legume Medicago truncatula. Plant Physiol 130(2):519-537.
8. Mergaert P, et al. (2003) A novel family in Medicago truncatula consisting of more than 300 nodule-specific genes coding for small, secreted polypeptides with conserved cysteine motifs. Plant Physiol 132(1):161-173.
9. Maróti G, Kondorosi E (2014) Nitrogen-fixing Rhizobium-legume symbiosis: Are polyploidy and host peptide-governed symbiont differentiation general principles of endosymbiosis? Front Microbiol 5:326.
10. Farkas A, et al. (2014) Medicago truncatula symbiotic peptide NCR247 contributes to bacteroid differentiation through multiple mechanisms. Proc Natl Acad Sci USA 111(14):5183-5188.
11. Penterman J, et al. (2014) Host plant peptides elicit a transcriptional response to control the Sinorhizobium meliloti cell cycle during symbiosis. Proc Natl Acad Sci USA 111(9):3561-3566.
12. Starker CG, Parra-Colmenares AL, Smith L, Mitra RM, Long SR (2006) Nitrogen fixation mutants of Medicago truncatula fail to support plant and bacterial symbiotic gene expression. Plant Physiol 140(2):671-680.
13. Bourcy M, et al. (2013) Medicago truncatula DNF2 is a PI-PLC-XD-containing protein required for bacteroid persistence and prevention of nodule early senescence and defense-like reactions. New Phytol 197(4):1250-1261.
14. Petersen TN, Brunak S, von Heijne G, Nielsen H (2011) SignalP 4.0: Discriminating signal peptides from transmembrane regions. Nat Methods 8(10):785-786.
15. Xi J, Chen Y, Nakashima J, Wang SM, Chen R (2013) Medicago truncatula esn1 defines a genetic locus involved in nodule senescence and symbiotic nitrogen fixation. Mol Plant Microbe Interact 26(8):893-902.
16. Nallu S, et al. (2013) Regulatory patterns of a large family of defensin-like genes expressed in nodules of Medicago truncatula. PLoS One 8(4):e60355.
17. Roux B, et al. (2014) An integrated analysis of plant and bacterial gene expression in symbiotic root nodules using laser-capture microdissection coupled to RNA sequencing. Plant J 77(6):817-837.
18. Zhang N, et al. (2004) Solution structure of BmKK2, a new potassium channel blocker from the venom of Chinese scorpion Buthus martensi Karsch. Proteins 55(4):835-845.
19. Zhou P, et al. (2013) Detecting small plant peptides using SPADA (Small Peptide Alignment Discovery Application). BMC Bioinformatics 14:335.
20. Oono R, Denison RF (2010) Comparing symbiotic efficiency between swollen versus nonswollen rhizobial bacteroids. Plant Physiol 154(3):1541-1548.
21. Leong SA, Williams PH, Ditta GS (1985) Analysis of the 5′ regulatory region of the gene for delta-aminolevulinic acid synthetase of Rhizobium meliloti. Nucleic Acids Res 13(16):5965-5976.
22. Gage DJ (2002) Analysis of infection thread development using Gfp-and DsRed-expressing Sinorhizobium meliloti. J Bacteriol 184(24):7042-7046.
23. Curtis MD, Grossniklaus U (2003) A gateway cloning vector set for high-throughput functional analysis of genes in planta. Plant Physiol 133(2):462-469.
24. Smit P, et al. (2005) NSP1 of the GRAS protein family is essential for rhizobial Nod factor-induced transcription. Science 308(5729):1789-1791.
25. Hong SW, Vierling E (2000) Mutants of Arabidopsis thaliana defective in the acquisition of tolerance to high-temperature stress. Proc Natl Acad Sci USA 97(8):4392-4397.
26. Thorvaldsdóttir H, Robinson JT, Mesirov JP (2013) Integrative Genomics Viewer (IGV): High-performance genomics data visualization and exploration. Brief Bioinform 14(2):178-192.
27. Boisson-Dernier A, et al. (2001) Agrobacterium rhizogenes-transformed roots of Medicago truncatula for the study of nitrogen-fixing and endomycorrhizal symbiotic associations. Mol Plant Microbe Interact 14(6):695-700.
28. Horváth B, et al. (2015) Loss of the nodule-specific cysteine rich peptide, NCR169, abolishes symbiotic nitrogen fixation in the Medicago truncatula dnf7 mutant. Proc Natl Acad Sci USA 112:15232-15237.
29. Price PA, et al. (2015) Rhizobial peptidase HrrP cleaves host-encoded signaling peptides and mediates symbiotic compatibility. Proc Natl Acad Sci USA 112:15244-15249.