Factors associated with clinical research recruitment in a pediatric Academic Medical Center-A web-based survey

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Denhoff, Erica Rose ^a   Milliren, Carly E ^a   De Ferranti, Sarah D ^a   Steltz, Sarah K ^a   Osganian, Stavroula K ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; CHI SQUARE TEST; CHILD; CLINICAL RESEARCH; CONTROLLED STUDY; DOCTOR PATIENT RELATION; FAMILY; FAMILY STUDY; HUMAN; HUMAN EXPERIMENT; INSTITUTIONAL REVIEW; LOGISTIC REGRESSION ANALYSIS; MANTEL HAENSZEL TEST; PEDIATRIC HOSPITAL; PREDICTOR VARIABLE; STUDY DESIGN; UNITED STATES; CLINICAL TRIAL (TOPIC); FEMALE; INTERNET; MALE; QUESTIONNAIRE;

ADULT; CLINICAL TRIALS AS TOPIC; FEMALE; HUMANS; INTERNET; MALE; SURVEYS AND QUESTIONNAIRES;

EID: 84949225533     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0140768     Document Type: Article

References (18)

1. Anderson DL. A Guide to Patient Recruitment-Today's Best Practices and Proven Strategies. Boston: CenterWatch; 2002.
2. Treweek S, Pitkethly M, Cook J, Kjeldstram M, Taskila T, Johansen M, et al. Strategies to improve recruitment to randomised controlled trials. Cochrane Database Syst Rev. 2010; 14;43.
3. Hunninghake DB, Darby CA, Probstfield JL. Recruitment experience in clinical trials: literature summary and annotated bibliography. Control Clin Trials. 1987; 8 (4 Suppl): 6S-30S.
4. Ross S, Grant A, Counsell C, Gillespie W, Russell I, Prescott R. Barriers to participation in randomised controlled trials: a systematic review. J Clin Epidemiol. 1999; 52(12):1143-56. PMID: 10580777
5. Fayter D, McDaid C, Eastwood A. A systematic review highlights threats to validity in studies of barriers tocancertrial participation. J Clin Epidemiol. 2007; 60(10):990-1001. PMID: 17884592
6. Tishler CL, Reiss NS. Pediatric drug-trial recruitment: enticement without coercion. Pediatrics.2011; 127(5):949-54. doi: 10.1542/peds.2010-2585 PMID: 21464193
7. Treweek S, Lockhart P, Pitkethly M, Cook JA, Kjeldstram M, Johansen M, et al. Methods to improve recruitment to randomised controlled trials: Cochrane systematic review and meta-analysis. BMJ Open. 2013 Feb 7; 3(2)pii: e002360. doi: 10.1136/bmjopen-2012-002360 PMID: 23396504
8. Caldwell PH, Hamilton S, Tan A, Craig JC. Strategies for increasing recruitment to randomised controlled trials: systematic review. PLoSMed. 2010 Nov 9; 7(11):e1000368. doi: 10.1371/journal.pmed. 1000368 PMID: 21085696
9. Spaar A, Frey M, Turk A, Karner W, Puhan MA: Recruitment barriers in a randomized controlled trial from the physicians' perspective: a postal survey. BMC Medical Research Methodology. 2009; 9:14 doi: 10.1186/1471-2288-9-14 PMID: 19254374
10. Pinnow E, Ritchey ME, Van Dole KB, Loyo-berrios N. Identifying Obstacles and Opportunities for Recruitment and Retention in Clinical Research. Monitor. 2010;59-64.
11. Shamliyan T, Kane RL. Clinical research involving children: registration, completeness, and publication. Pediatrics. 2012; 129(5):e1291-300. doi: 10.1542/peds.2010-2847 PMID: 22529271
12. Kasenda B, von Elm E, You J, Blümle A, Tomonaga Y, Saccilotto R, et al. Prevalence, characteristics, and publication of discontinued randomized trials. JAMA. 2014; 311(10):1045-51. doi: 10.1001/jama. 2014.1361 PMID: 24618966
13. Kitterman DR, Cheng SK, Dilts DM, Orwoll ES. The prevalence and economic impact of low-enrolling clinical studies at an academic medical center. Acad Med. 2011; 86(11):1360-6. doi: 10.1097/ACM. 0b013e3182306440 PMID: 21952064
14. Kost RG, Lee LM, Yessis J, Wesley RA, Henderson DK, Coller BS. Assessing participant-centered outcomes to improve clinical research. N Engl J Med. 2013; 369(23):2179-81. doi: 10.1056/NEJMp1311461 PMID: 24304050
15. Felsen CB, Shaw EK, Ferrante JM, Lacroix LJ, Crabtree BF. Strategies for in-person recruitment: lessons learned from a New Jersey primary care research network (NJPCRN) study. J Am Board Fam Med. 2010 Jul-Aug; 23(4):523-33. doi: 10.3122/jabfm.2010.04.090096 PMID: 20616295
16. Menon K, Ward RE, Gaboury I, Thomas M, Joffe A, Burns K, Cook D. Factors affecting consent in pediatric critical care research. Intensive Care Med. 2012; 38(1):153-9. doi: 10.1007/s00134-011-2412-0 PMID: 22120768
17. Saldaña SN, Hooper DK, Froehlich TE, Campbell KM, Prows CA, Sadhasivam S, et al. Characteristics of successful recruitment in prospective pediatric pharmacogenetic studies. Clin Ther. 2011; 33 (12):2072-81. doi: 10.1016/j.clinthera.2011.10.026 PMID: 22136977
18. Kaguelidou F, Amiel P, Blachier A, Iliescu C, Rozé JC, Tsimaratos M, et al. Recruitment in pediatric clinical research was influenced by study characteristics and pediatricians' perceptions: a multicenter survey. J Clin Epidemiol. 2013; 66(10):1151-7. doi: 10.1016/j.jclinepi.2013.04.015 PMID: 23856188