메뉴 건너뛰기




Volumn 2, Issue 1, 2015, Pages

Association of the interferon signature metric with serological disease manifestations but not global activity scores in multiple cohorts of patients with SLE

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; B CELL ACTIVATING FACTOR; CELL NUCLEUS ANTIGEN; INTERFERON; RITUXIMAB; RONTALIZUMAB; TUMOR NECROSIS FACTOR;

EID: 84949212787     PISSN: None     EISSN: 20538790     Source Type: Journal    
DOI: 10.1136/lupus-2014-000080     Document Type: Article
Times cited : (106)

References (30)
  • 1
    • 0015124633 scopus 로고
    • Systemic lupus erythematosus: Prototype of immune complex nephritis in man
    • Koffler D, Agnello V, Thoburn R, et al. Systemic lupus erythematosus: prototype of immune complex nephritis in man. J Exp Med 1971;134:169s-79s.
    • (1971) J Exp Med , vol.134 , pp. 169s-179s
    • Koffler, D.1    Agnello, V.2    Thoburn, R.3
  • 2
    • 37349066319 scopus 로고    scopus 로고
    • Complement deficiencies and systemic lupus erythematosus
    • Truedsson L, Bengtsson AA, Sturfelt G. Complement deficiencies and systemic lupus erythematosus. Autoimmunity 2007;40:560-6.
    • (2007) Autoimmunity , vol.40 , pp. 560-566
    • Truedsson, L.1    Bengtsson, A.A.2    Sturfelt, G.3
  • 3
    • 39549111438 scopus 로고    scopus 로고
    • Anti-DNA antibodies in the pathogenesis of lupus nephritis-the emerging mechanisms
    • Yung S, Chan TM. Anti-DNA antibodies in the pathogenesis of lupus nephritis-the emerging mechanisms. Autoimmun Rev 2008;7:317-21.
    • (2008) Autoimmun Rev , vol.7 , pp. 317-321
    • Yung, S.1    Chan, T.M.2
  • 4
    • 80051729839 scopus 로고    scopus 로고
    • Measuring outcomes in systemic lupus erythematosus clinical trials
    • Strand V, Chu AD. Measuring outcomes in systemic lupus erythematosus clinical trials. Exp Rev Pharmacoec Outcomes Res 2011;11:455-68.
    • (2011) Exp Rev Pharmacoec Outcomes Res , vol.11 , pp. 455-468
    • Strand, V.1    Chu, A.D.2
  • 5
    • 10044261111 scopus 로고    scopus 로고
    • Defining response in systemic lupus erythematosus: A study by the Systemic Lupus International Collaborating Clinics group
    • Wollaston SJ, Farewell VT, Isenberg DA, et al. Defining response in systemic lupus erythematosus: A study by the Systemic Lupus International Collaborating Clinics group. J Rheum 2004;31:2390-4.
    • (2004) J Rheum , vol.31 , pp. 2390-2394
    • Wollaston, S.J.1    Farewell, V.T.2    Isenberg, D.A.3
  • 6
    • 84873404949 scopus 로고    scopus 로고
    • The interferon signature in autoimmune diseases
    • Ronnblom L, Eloranta ML. The interferon signature in autoimmune diseases. Curr Opin Rheum 2013;25:248-53.
    • (2013) Curr Opin Rheum , vol.25 , pp. 248-253
    • Ronnblom, L.1    Eloranta, M.L.2
  • 7
    • 33748447541 scopus 로고    scopus 로고
    • Type i interferon in systemic lupus erythematosus and other autoimmune diseases
    • Banchereau J, Pascual V. Type I interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity 2006;25:383-92.
    • (2006) Immunity , vol.25 , pp. 383-392
    • Banchereau, J.1    Pascual, V.2
  • 8
    • 79955694610 scopus 로고    scopus 로고
    • Type i interferon in organ-targeted autoimmune and inflammatory diseases
    • Crow MK. Type I interferon in organ-targeted autoimmune and inflammatory diseases. Arth Res Ther 2010;12(Suppl 1):S5.
    • (2010) Arth Res Ther , vol.12 , pp. S5
    • Crow, M.K.1
  • 9
    • 84867745567 scopus 로고    scopus 로고
    • The genetics of type i interferon in systemic lupus erythematosus
    • Bronson PG, Chaivorapol C, Ortmann W, et al. The genetics of type I interferon in systemic lupus erythematosus. Curr Opin Immun 2012;24:530-7.
    • (2012) Curr Opin Immun , vol.24 , pp. 530-537
    • Bronson, P.G.1    Chaivorapol, C.2    Ortmann, W.3
  • 10
    • 0344492212 scopus 로고    scopus 로고
    • Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
    • Baechler EC, Batliwalla FM, Karypis G, et al. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc Nat Acad Sci 2003;100:2610-5.
    • (2003) Proc Nat Acad Sci , vol.100 , pp. 2610-2615
    • Baechler, E.C.1    Batliwalla, F.M.2    Karypis, G.3
  • 11
    • 0037451167 scopus 로고    scopus 로고
    • Interferon and granulopoiesis signatures in systemic lupus erythematosus blood
    • Bennett L, Palucka AK, Arce E, et al. Interferon and granulopoiesis signatures in systemic lupus erythematosus blood. J Exp Med 2003;197:711-23.
    • (2003) J Exp Med , vol.197 , pp. 711-723
    • Bennett, L.1    Palucka, A.K.2    Arce, E.3
  • 12
    • 80053495592 scopus 로고    scopus 로고
    • Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type i interferon pathway
    • Higgs BW, Liu Z, White B, et al. Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway. Ann Rheum Dis 2011;70:2029-36.
    • (2011) Ann Rheum Dis , vol.70 , pp. 2029-2036
    • Higgs, B.W.1    Liu, Z.2    White, B.3
  • 13
    • 32444451688 scopus 로고    scopus 로고
    • The type i interferon system in systemic lupus erythematosus
    • Ronnblom L, Eloranta ML, Alm GV. The type I interferon system in systemic lupus erythematosus. Arthritis Rheum 2006;54:408-20.
    • (2006) Arthritis Rheum , vol.54 , pp. 408-420
    • Ronnblom, L.1    Eloranta, M.L.2    Alm, G.V.3
  • 14
    • 84861235405 scopus 로고    scopus 로고
    • Emerging therapies for systemic lupus erythematosus-focus on targeting interferon-alpha
    • Lichtman EI, Helfgott SM, Kriegel MA. Emerging therapies for systemic lupus erythematosus-focus on targeting interferon-alpha. Clin Immunol 2012;143:210-21.
    • (2012) Clin Immunol , vol.143 , pp. 210-221
    • Lichtman, E.I.1    Helfgott, S.M.2    Kriegel, M.A.3
  • 15
    • 79961110602 scopus 로고    scopus 로고
    • Association of endogenous anti-interferon-alpha autoantibodies with decreased interferonpathway and disease activity in patients with systemic lupus erythematosus
    • Morimoto AM, Flesher DT, Yang J, et al. Association of endogenous anti-interferon-alpha autoantibodies with decreased interferonpathway and disease activity in patients with systemic lupus erythematosus. Arthritis Rheum 2011;63:2407-15.
    • (2011) Arthritis Rheum , vol.63 , pp. 2407-2415
    • Morimoto, A.M.1    Flesher, D.T.2    Yang, J.3
  • 16
    • 84868144947 scopus 로고    scopus 로고
    • Safety and pharmacodynamics of rontalizumab in patients with systemic lupus erythematosus: Results of a phase I, placebo-controlled, double-blind, dose-escalation study
    • McBride JM, Jiang J, Abbas AR, et al. Safety and pharmacodynamics of rontalizumab in patients with systemic lupus erythematosus: results of a phase I, placebo-controlled, double-blind, dose-escalation study. Arthritis Rheum 2012;64:3666-76.
    • (2012) Arthritis Rheum , vol.64 , pp. 3666-3676
    • McBride, J.M.1    Jiang, J.2    Abbas, A.R.3
  • 17
    • 74849131972 scopus 로고    scopus 로고
    • Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: The randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial
    • Merrill JT, Neuwelt CM, Wallace DJ, et al. Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: The randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial. Arthritis Rheum 2010;62:222-33.
    • (2010) Arthritis Rheum , vol.62 , pp. 222-233
    • Merrill, J.T.1    Neuwelt, C.M.2    Wallace, D.J.3
  • 18
    • 79957617387 scopus 로고    scopus 로고
    • Assessment of flares in lupus patients enrolled in a phase II/III study of rituximab (EXPLORER)
    • Merrill J, Buyon J, Furie R, et al. Assessment of flares in lupus patients enrolled in a phase II/III study of rituximab (EXPLORER). Lupus 2011;20:709-16.
    • (2011) Lupus , vol.20 , pp. 709-716
    • Merrill, J.1    Buyon, J.2    Furie, R.3
  • 19
    • 84954384327 scopus 로고    scopus 로고
    • A Phase II study of the efficacy and safety of rontalizumab (rhuMAb interferon-?) in systemic lupus erythematosus patients (ROSE)
    • Kalunian KC, Merrill JT, Maciuca R, et al. A Phase II study of the efficacy and safety of rontalizumab (rhuMAb interferon-?) in systemic lupus erythematosus patients (ROSE). Ann Rheum Dis 2015. doi: 10.1136/annrheumdis-2014-206090.
    • (2015) Ann Rheum Dis
    • Kalunian, K.C.1    Merrill, J.T.2    Maciuca, R.3
  • 20
    • 77953095629 scopus 로고    scopus 로고
    • Independent filtering increases detection power for high-throughput experiments
    • Bourgon R, Gentleman R, Huber W. Independent filtering increases detection power for high-throughput experiments. Proc Natl Acad Sci 2010;107:9546-51.
    • (2010) Proc Natl Acad Sci , vol.107 , pp. 9546-9551
    • Bourgon, R.1    Gentleman, R.2    Huber, W.3
  • 21
    • 0031692656 scopus 로고    scopus 로고
    • The proximal interferon-stimulated response elements are essential for interferon responsiveness: A promoter analysis of the antiviral MxA gene
    • Ronni T, Matikainen S, Lehtonen A, et al. The proximal interferon-stimulated response elements are essential for interferon responsiveness: A promoter analysis of the antiviral MxA gene. J Interferon Cytokine Res 1998;18:773-81.
    • (1998) J Interferon Cytokine Res , vol.18 , pp. 773-781
    • Ronni, T.1    Matikainen, S.2    Lehtonen, A.3
  • 22
    • 0035905409 scopus 로고    scopus 로고
    • A pivotal role for the natural interferon alpha-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus
    • Ronnblom L, Alm GV. A pivotal role for the natural interferon alpha-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus. J Exp Med 2001;194:F59-63.
    • (2001) J Exp Med , vol.194 , pp. F59-63
    • Ronnblom, L.1    Alm, G.V.2
  • 23
    • 85047693371 scopus 로고    scopus 로고
    • Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9
    • Means TK, Latz E, Hayashi F, et al. Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9. J Clin Invest 2005;115:407-17.
    • (2005) J Clin Invest , vol.115 , pp. 407-417
    • Means, T.K.1    Latz, E.2    Hayashi, F.3
  • 24
    • 58049202272 scopus 로고    scopus 로고
    • Innate immunity to virus infection
    • Takeuchi O, Akira S. Innate immunity to virus infection. Immunol Rev 2009;227:75-86.
    • (2009) Immunol Rev , vol.227 , pp. 75-86
    • Takeuchi, O.1    Akira, S.2
  • 25
    • 84873711885 scopus 로고    scopus 로고
    • Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type i interferon pathway
    • Sun L, Wu J, Du F, et al. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 2013;339:786-91.
    • (2013) Science , vol.339 , pp. 786-791
    • Sun, L.1    Wu, J.2    Du, F.3
  • 26
    • 77953723966 scopus 로고    scopus 로고
    • TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus
    • Guiducci C, Gong M, Xu Z, et al. TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus. Nature 2010;465:937-41.
    • (2010) Nature , vol.465 , pp. 937-941
    • Guiducci, C.1    Gong, M.2    Xu, Z.3
  • 27
    • 84875697484 scopus 로고    scopus 로고
    • Sifalimumab, a human anti-interferon-alpha monoclonal antibody, in systemic lupus erythematosus: A phase i randomized, controlled, dose-escalation study
    • Petri M, Wallace DJ, Spindler A, et al. Sifalimumab, a human anti-interferon-alpha monoclonal antibody, in systemic lupus erythematosus: A phase I randomized, controlled, dose-escalation study. Arthritis Rheum 2013;65:1011-21.
    • (2013) Arthritis Rheum , vol.65 , pp. 1011-1021
    • Petri, M.1    Wallace, D.J.2    Spindler, A.3
  • 28
    • 84901641596 scopus 로고    scopus 로고
    • Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type i and type II interferon signatures
    • Chiche L, Jourde-Chiche N, Whalen E, et al. Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures. Arthritis Rheumatol 2014;66:1583-95.
    • (2014) Arthritis Rheumatol , vol.66 , pp. 1583-1595
    • Chiche, L.1    Jourde-Chiche, N.2    Whalen, E.3
  • 29
    • 84859992161 scopus 로고    scopus 로고
    • The JAK-STAT pathway at twenty
    • Stark GR, Darnell JE Jr. The JAK-STAT pathway at twenty. Immunity 2012;36:503-14.
    • (2012) Immunity , vol.36 , pp. 503-514
    • Stark, G.R.1    Darnell, J.E.2
  • 30
    • 84913559696 scopus 로고    scopus 로고
    • Lymphotoxin-LIGHT pathway regulates the interferon signature in rheumatoid arthritis
    • Bienkowska J, Allaire N, Thai A, et al. Lymphotoxin-LIGHT pathway regulates the interferon signature in rheumatoid arthritis. PLoS One 2014;9:e112545.
    • (2014) PLoS One , vol.9 , pp. e112545
    • Bienkowska, J.1    Allaire, N.2    Thai, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.