Body fat patterning, hepatic fat and pancreatic volume of non-obese asian indians with type 2 diabetes in North India: A case-control study

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Misra, Anoop ^a,b,c,d   Anoop, Shajith ^a,b   Gulati, Seema ^a,b   Mani, Kalaivani ^e   Bhatt, Surya Prakash ^a,b   Pandey, Ravindra Mohan ^e  

^a Obesity and Cholesterol Diseases Foundation N DOC   (India)

^b Diabetes Foundation India New Delhi   (India)

^c Fortis C DOC Centre of Excellence for Diabetes Metabolic Diseases and Endocrinology   (India)

^d FORTIS HOSPITAL   (India)

^e ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; ASIAN; BODY FAT; CASE CONTROL STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; FATTY LIVER; FEMALE; HEPATIC FAT; HIP CIRCUMFERENCE; HUMAN; INDIA; INTRAABDOMINAL FAT; LIPID STORAGE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; ORGAN SIZE; PANCREATIC VOLUME; RETROPERITONEAL FAT; SKINFOLD THICKNESS; SUBCUTANEOUS FAT; WAIST CIRCUMFERENCE; ADOLESCENT; BODY FAT DISTRIBUTION; COMPLICATION; METABOLISM; PANCREAS; PATHOLOGY; YOUNG ADULT;

ADOLESCENT; ADULT; BODY FAT DISTRIBUTION; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 2; FATTY LIVER; FEMALE; HUMANS; INDIA; MALE; ORGAN SIZE; PANCREAS; SKINFOLD THICKNESS; YOUNG ADULT;

EID: 84949192612     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0140447     Document Type: Article

References (31)

1. Misra A, Shrivastava U. Obesity and Dyslipidaemia in South Asians. Nutrients.2013; 5: 2708-2733. doi: 10.3390/nu5072708 PMID: 23863826
2. Chen L, Magliano DJ, Zimmet PZ. The worldwide epidemiology of type 2 diabetes mellitus - present and future perspectives. Nat Rev Endocrinol.2011; 8: 228-236. doi: 10.1038/nrendo.2011.183 PMID: 22064493
3. Misra A, Madhavan M, Vikram NK, Pandey RM, Dhingra V, Luthra K. Simple anthropometric measures predict fasting hyperinsulinemia and clustering of cardiovascular risk factors in Asian Indian adolescents. Metabolism.2006; 55:1569-73 PMID: 17142126
4. Frayling TM, Wiltshire S, Hitman GA, Walker M, Levy JC, Sampson M, et al. Young-Onset Type 2 Diabetes families are the major contributors to genetic loci in the diabetes UK Warren 2 genome scan and identify putative novel loci on Chromosomes 8q21, 21q22, and 22q11. Diabetes. 2003; 52: 1857-1863 PMID: 12829657
5. Barker DJ. Intrauterine programming of adult disease. Mol Med Today.1995; 1: 418-423. PMID: 9415190
6. Hattersley AT, Tooke JE. The fetal insulin hypothesis: an alternative explanation of the association of low birth weight with diabetes and vascular disease. Lancet.1999; 353:1789-1792. PMID: 10348008
7. Misra A, Khurana L. Obesity related non-communicable diseases: South Asians vs.White Caucasians. Int J Obesity. 2011; 35: 167-187.
8. Misra A, Alappan NK, Vikram NK, Goel K, Gupta N, Mittal K, et al. Effect of supervised progressive resistance-exercise training protocol on insulin sensitivity, glycemia, lipids, and body composition in Asian Indians with type 2 diabetes. Diabetes Care.2008; 31:1282-1287. doi: 10.2337/dc07-2316 PMID: 18316394
9. Misra A. Impact of ethnicity on body fat patterning in Asian Indians and Blacks: Relationship with insulin resistance. Nutrition. 2003; 19:815-816 PMID: 12921898
10. Misra A, Wasir JS, Vikram NK, Pandey RM, Kumar P. Cut-offs of abdominal adipose tissue compartments as measured by magnetic resonance imaging for detection of cardiovascular risk factors in apparently healthy adults Asian Indians in North India. Metab Syndr Relat Disord. 2010; 8: 243-247 doi: 10.1089/met.2009.0046 PMID: 20156066
11. Goel K, Misra A, Vikram NK, Poddar P, Gupta N. Subcutaneous abdominal adipose tissue is associated with the metabolic syndrome in Asian Indians independent of intra-abdominal and total body fat. Heart. 2010; 96: 579-583. doi: 10.1136/hrt.2009.183236 PMID: 20357386
12. Nigam P, Bhatt SP, Misra A, Vaidya M, Dasgupta J, Chadha DS. Non-alcoholic fatty liver disease is closely associated with sub-clinical inflammation: A case-control study on Asian Indians in North India. PLoS One. 2013; 8: e49286. doi: 10.1371/journal.pone.0049286 PMID: 23326306
13. Dudeja V, Misra A, Pandey RM, Devina G, Kumar G, Vikram NK. BMI does not accurately predict overweight in Asian Indians in northern India. Brit J Nutr. 2001; 86:105-112. PMID: 11432771
14. Shen W, Wang Z, Punyanita M, Lei J, Sinav A, Kral JG, et al. Adipose Tissue Quantification by Imaging Methods: A Proposed Classification. Obes Res. 2003; 11: 5-16 PMID: 12529479
15. Permutt Z, Le TA, Peterson MR, Seki E, Brenner DA, Sirlin C. Correlation between liver histology and novel magnetic resonance imaging in adult patients with non-alcoholic fatty liver disease - MRI accurately quantifies hepatic steatosis in NAFLD. Aliment Pharmacol and Ther. 2012; 36: 22-29
16. Goda K, Sasaki E, Nagata K, Fukai M, Ohsawa N, Hahafusa T. Pancreatic volume in type 1 and type 2 diabetes mellitus. Acta Diabetologica. 2001; 38: 145-149. PMID: 11827436
17. The IDF consensus worldwide definition of metabolic syndrome. Available: http://www.idf.org/webdata/ docs/MetS-def-update2006.pdf. Accessed 04 August 2015.
18. Chandalia M, Lin P, Seenivasan T, Livingston EH, Snell PG, Grundy SM. Insulin resistance and body fat distribution in South Asian men compared to Caucasian Men. PLoS One. 2007; 2: e812 PMID: 17726542
19. Abate N, Garg A, Peshock RM, Gundersen JS, Grundy SM. Relationships of generalized and regional adiposity to insulin sensitivity in men. J Clin Invest. 1995; 96: 88-98 PMID: 7615840
20. Unger RM. Lipotoxicity in the pathogenesis of obesity-dependent NIDDM: Genetic and clinical implications. Diabetes.1995; 44: 863-870 PMID: 7621989
21. Kim JW, Yoon KH. Glucolipotoxicity in Pancreatic β-Cells. Diabetes Metab J. 2011; 35: 444-450. doi: 10.4093/dmj.2011.35.5.444 PMID: 22111034
22. Kruit JK, Brunham LR, Verchere CB, Hayden MR. HDL and LDL cholesterol significantly influence beta-cell function in type 2 diabetes mellitus. Curr Opin Lipidol. 2010; 21: 178-85. doi: 10.1097/MOL. 0b013e328339387b PMID: 20463468
23. Lindroos AS, Vehkavaara S, Hakkinen AM, Goto T, Westerbacka J, Sovijärvi A. Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men. J Clin Endocrinol Metab. 2002; 87:3023-3028 PMID: 12107194
24. Petersen KF, Dufour S, Feng J, Befroy D, Dziura J, Dalla Man C. Increased prevalence of insulin resistance and non-alcoholic fatty liver disease in Asian-Indian men. Proc Natl Acad Sci USA.2006; 103: 18273-18277 PMID: 17114290
25. Misra A, Sinha S, Kumar M, Jagannathan NR, Pandey RM. Proton magnetic resonance spectroscopy study of soleus muscle in non-obese healthy and type 2 diabetic Asian Northern Indian males: high intra myocellular lipid content correlates with excess body fat and abdominal obesity. Diabet Med. 2003; 20:361-367 PMID: 12752484
26. Perry RJ, Samuel VT, Petersen KF, Shulman GI. The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes. Nature. 2014; 510:84-91 doi: 10.1038/nature13478 PMID: 24899308
27. Bhatt SP, Nigam P, Misra A, Guleria R, Pandey RM, Pasha MA. Genetic variation in patatin - like phospholipase domain containing protein-3 (PNPLA 3) gene in Asian Indians with non-alcoholic fatty liver disease. Metab Syndr Relat Disord. 2013; 11: 329-335. doi: 10.1089/met.2012.0064 PMID: 23734760
28. Abate N, Chandalia M, Snell PG, Grundy SM. Adipose tissue metabolites in non-diabetic Asian Indian men. J Clin Endocrinol Metab.2004; 89:2750-2755 PMID: 15181053
29. Burute N, Nisenbaum R, Jenkins DJ, Mirrahimi A, Anthwal S, Colak E. Pancreas volume measurement in patients with Type 2 diabetes using magnetic resonance based planimetry. Pancreatology. 2014; 14: 268-274 doi: 10.1016/j.pan.2014.04.031 PMID: 25062875
30. Saisho Y, Butler AE, Meier JJ, Monchamp T, Allen-Auerbach M, Rizza RA. Pancreas volumes in humans from birth to age one hundred taking into account sex, obesity, and presence of type-2 diabetes. Clin Anat. 2007; 20: 933-942. PMID: 17879305
31. Lingvay I, Esser V, Legendre JL, Price AL,Wertz KM, Adams-Huet B. Noninvasive quantification of pancreatic fat in humans. J Clin Endocrinol Metab. 2009; 94: 4070-4076. doi: 10.1210/jc.2009-0584 PMID: 19773401