Mutations in NONO lead to syndromic intellectual disability and inhibitory synaptic defects

Nature Neuroscience

Volumn 18, Issue 12, 2015, Pages 1731-1736

  Mircsof, Dennis ^a   Langouët, Maéva ^b   Rio, Marlène ^b,c   Moutton, Sébastien ^b   Siquier Pernet, Karine ^b   Bole Feysot, Christine ^b   Cagnard, Nicolas ^b   Nitschke, Patrick ^b   Gaspar, Ludmila ^a   Žnidariɥ, Matej ^a   Alibeu, Olivier ^b   Fritz, Ann Kristina ^a   Wolfer, David P ^a   Schröter, Aileen ^a   Bosshard, Giovanna ^a   Rudin, Markus ^a   Koester, Christina ^a   Crestani, Florence ^a   Seebeck, Petra ^a   Boddaert, Nathalie ^b,c   Prescott, Katrina ^d   Hines, Rochelle ^e   Moss, Steven J ^e   Fritschy, Jean Marc ^a   Munnich, Arnold ^b   Amiel, Jeanne ^b,c   Brown, Steven A ^a   Tyagarajan, Shiva K ^a   Colleaux, Laurence ^b   more..

^a UNIVERSITY OF ZURICH   (Switzerland)

^b PARIS DESCARTES SORBONNE PARIS CITÉ UNIVERSITY   (France)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

^d CHAPEL ALLERTON HOSPITAL   (United Kingdom)

^e TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2; GEPHYRIN; MESSENGER RNA; NONO PROTEIN; REGULATOR PROTEIN; RNA; TRANSCRIPTOME; UNCLASSIFIED DRUG; NONO PROTEIN, HUMAN; NUCLEAR MATRIX PROTEIN; OCTAMER TRANSCRIPTION FACTOR; RNA BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CASE REPORT; COGNITIVE DEFECT; CONTROLLED STUDY; GABAERGIC SYSTEM; GENE EXPRESSION; HUMAN; HUMAN CELL; INTELLECTUAL IMPAIRMENT; LOSS OF FUNCTION MUTATION; MALE; MOOD DISORDER; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN STRUCTURE; SPECIES COMPARISON; SYNAPSE; SYNAPTIC INHIBITION; TRANSCRIPTION REGULATION; ADOLESCENT; ANIMAL; BRAIN; C57BL MOUSE; CELL CULTURE; GENETICS; INTELLECTUAL DISABILITY; MUTATION; NERVE CELL INHIBITION; PATHOLOGY; PEDIGREE; TRANSGENIC MOUSE;

ADOLESCENT; ANIMALS; BRAIN; CELLS, CULTURED; HUMANS; INTELLECTUAL DISABILITY; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; NEURAL INHIBITION; NUCLEAR MATRIX-ASSOCIATED PROTEINS; OCTAMER TRANSCRIPTION FACTORS; PEDIGREE; RNA-BINDING PROTEINS; SYNAPSES;

EID: 84949132230     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.4169     Document Type: Article

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