Mechanisms of corneal allograft rejection

Ocular Surface

Volumn 3, Issue 4, 2005, Pages S165-S168

  Coster, Douglas J ^a   Jessup, Claire F ^a   Williams, Keryn A ^a  

^a FLINDERS UNIVERSITY   (Australia)

Author keywords

Antigen presentation; Corneal transplantation; Engineered antibodies; Gene transfer; Rejection

Indexed keywords

MONOCLONAL ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; CORNEA ALLOGRAFT REJECTION; CORNEA TRANSPLANTATION; DNA MODIFICATION; GENE THERAPY; GRAFT REJECTION; GRAFT SURVIVAL; HUMAN; IMMUNE RESPONSE; NONHUMAN;

EID: 84949116118     PISSN: 15420124     EISSN: 19375913     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Williams KA, Hornsby NB, Bartlett CM, et al (eds). The Australian corneal graft registry 2004 report. Adelaide, Snap Printing, 2004: pp 1-192
2. http://www.anzdata.org.au/ANZDATA/anzdatawelcome.htm
3. Katami M, Madden PW, White DJ, et al. The extent of immunological privilege of orthotopic corneal grafts in the inbred rat. Transplantation 1989;48:371-6
4. Niederkorn JY. Mechanisms of corneal graft rejection: the sixth annual Thygeson Lecture. Cornea 2001;20:675-9
5. Williams KA, White MA, Ash JK, Coster DJ. Leucocytes in the graft bed are associated with corneal graft failure: analysis by immunohistology and actuarial graft survival. Ophthalmology 1989;96:38-44
6. Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989;7:145-73
7. Thiel MA, Coster DJ, Williams KA. The potential of antibodybased immunosuppressive agents for corneal transplantation. Immunol Cell Biol 2003;81:93-105
8. Thiel MA, Coster DJ, Standfield SD, et al. Penetration of engineered antibody fragments into the eye. Clin Exp Immunol 2002;128:67-74
9. Williams KA, Standfield SD, Mills RA, et al. A new model of orthotopic penetrating corneal transplantation in the sheep: graft survival, phenotypes of infiltrating cells and local cytokine production. Aust NZ J Ophthalmol 1999;27:127-35
10. Klebe S, Sykes PJ, Coster DJ, et al. Prolongation of sheep corneal allograft survival by transfer of the gene encoding ovine interleukin 10. Transplantation 2001;71:1214-20