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Volumn 59, Issue 4, 2015, Pages 2086-2093

Synergistic suppression of dengue virus replication using a combination of nucleoside analogs and nucleoside synthesis inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

BREQUINAR; INX 08189; NUCLEOSIDE ANALOG; RIBAVIRIN; UNCLASSIFIED DRUG; VIRUS RNA; ANTIVIRUS AGENT; BETA INTERFERON; DEHYDROOROTATE DEHYDROGENASE; DRUG COMBINATION; INTERFERON INDUCING AGENT; NUCLEOSIDE; OXIDOREDUCTASE;

EID: 84949114816     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.04779-14     Document Type: Article
Times cited : (51)

References (45)
  • 7
    • 84871380932 scopus 로고    scopus 로고
    • Characterization of 8-hydroxyquinoline derivatives containing aminobenzothiazole as inhibitors of dengue virus type 2 protease in vitro
    • Lai H, Sridhar Prasad G, Padmanabhan R. 2013. Characterization of 8-hydroxyquinoline derivatives containing aminobenzothiazole as inhibitors of dengue virus type 2 protease in vitro. Antiviral Res 97:74-80. http://dx.doi.org/10.1016/j.antiviral.2012.10.009.
    • (2013) Antiviral Res , vol.97 , pp. 74-80
    • Lai, H.1    Sridhar Prasad, G.2    Padmanabhan, R.3
  • 8
    • 84867236960 scopus 로고    scopus 로고
    • Structural biology of dengue virus enzymes: Towards rational design of therapeutics
    • Noble CG, Shi P-Y. 2012. Structural biology of dengue virus enzymes: towards rational design of therapeutics. Antiviral Res 96:115-126. http://dx.doi.org/10.1016/j.antiviral.2012.09.007.
    • (2012) Antiviral Res , vol.96 , pp. 115-126
    • Noble, C.G.1    Shi, P.-Y.2
  • 10
    • 80055106240 scopus 로고    scopus 로고
    • Inhibition of dengue virus by targeting viral NS4B protein
    • Xie X, Wang Q-Y, Xu HY, Qing M, Kramer L, Yuan Z, Shi P-Y. 2011. Inhibition of dengue virus by targeting viral NS4B protein. J Virol 85: 11183-11195. http://dx.doi.org/10.1128/JVI.05468-11.
    • (2011) J Virol , vol.85 , pp. 11183-11195
    • Xie, X.1    Wang, Q.-Y.2    Xu, H.Y.3    Qing, M.4    Kramer, L.5    Yuan, Z.6    Shi, P.-Y.7
  • 11
    • 35348920605 scopus 로고    scopus 로고
    • Virtual screening and bioassay study of novel inhibitors for dengue virus mRNA cap (nucleoside-2′O)-methyltransferase
    • Luzhkov VB, Selisko B, Nordqvist A, Peyrane F, Decroly E, Alvarez K, Karlen A, Canard B, Qvist J. 2007. Virtual screening and bioassay study of novel inhibitors for dengue virus mRNA cap (nucleoside-2′O)-methyltransferase. Bioorg Med Chem 15:7795-7802. http://dx.doi.org/10.1016/j.bmc.2007.08.049.
    • (2007) Bioorg Med Chem , vol.15 , pp. 7795-7802
    • Luzhkov, V.B.1    Selisko, B.2    Nordqvist, A.3    Peyrane, F.4    Decroly, E.5    Alvarez, K.6    Karlen, A.7    Canard, B.8    Qvist, J.9
  • 15
    • 84876340250 scopus 로고    scopus 로고
    • Conformational flexibility of the dengue virus RNA-dependent RNA polymerase revealed by a complex with an inhibitor
    • Noble CG, Lim SP, Chen Y-L, Liew CW, Yap L, Lescar J, Shi P-Y. 2013. Conformational flexibility of the dengue virus RNA-dependent RNA polymerase revealed by a complex with an inhibitor. J Virol 87:5291-5295. http://dx.doi.org/10.1128/JVI.00045-13.
    • (2013) J Virol , vol.87 , pp. 5291-5295
    • Noble, C.G.1    Lim, S.P.2    Chen, Y.-L.3    Liew, C.W.4    Yap, L.5    Lescar, J.6    Shi, P.-Y.7
  • 17
    • 84864925701 scopus 로고    scopus 로고
    • Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial
    • Watanabe S, Rathore APS, Sung C, Lu F, Khoo YM, Connolly J, Low J, Ooi EE, Lee HS, Vasudevan SG. 2012. Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial. Antiviral Res 96:32-35. http://dx.doi.org/10.1016/j.antiviral.2012.07.008.
    • (2012) Antiviral Res , vol.96 , pp. 32-35
    • Watanabe, S.1    Rathore, A.P.S.2    Sung, C.3    Lu, F.4    Khoo, Y.M.5    Connolly, J.6    Low, J.7    Ooi, E.E.8    Lee, H.S.9    Vasudevan, S.G.10
  • 19
    • 78149265507 scopus 로고    scopus 로고
    • A randomized controlled trial of chloroquine for the treatment of dengue in Vietnamese adults
    • Tricou V, Minh NN, Van TP, Lee SJ, Farrar J, Wills B, Tran HT, Simmons CP. 2010. A randomized controlled trial of chloroquine for the treatment of dengue in Vietnamese adults. PLoS Negl Trop Dis 4:e785. http://dx.doi.org/10.1371/journal.pntd.0000785.
    • (2010) PLoS Negl Trop Dis , vol.4 , pp. e785
    • Tricou, V.1    Minh, N.N.2    Van, T.P.3    Lee, S.J.4    Farrar, J.5    Wills, B.6    Tran, H.T.7    Simmons, C.P.8
  • 21
    • 0035738110 scopus 로고    scopus 로고
    • Antiviral activity and mode of action studies of ribavirin and mycophenolic acid against orthopoxviruses in vitro
    • Smee DF, Bray M, Huggins JW. 2001. Antiviral activity and mode of action studies of ribavirin and mycophenolic acid against orthopoxviruses in vitro. Antivir Chem Chemother 12:327-335.
    • (2001) Antivir Chem Chemother , vol.12 , pp. 327-335
    • Smee, D.F.1    Bray, M.2    Huggins, J.W.3
  • 23
    • 0019471668 scopus 로고
    • Inhibitors of IMP dehydrogenase prevent Sindbis virus replication and reduce GTP levels in Aedes albopictus cells
    • Malinoski F, Stollar V. 1981. Inhibitors of IMP dehydrogenase prevent Sindbis virus replication and reduce GTP levels in Aedes albopictus cells. Virology 110:281-289. http://dx.doi.org/10.1016/0042-6822(81)90060-X.
    • (1981) Virology , vol.110 , pp. 281-289
    • Malinoski, F.1    Stollar, V.2
  • 24
    • 13744258758 scopus 로고    scopus 로고
    • The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase
    • Leyssen P, Balzarini J, De Clercq E, Neyts J. 2005. The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase. J Virol 79:1943-1947. http://dx.doi.org/10.1128/JVI.79.3.1943-1947.2005.
    • (2005) J Virol , vol.79 , pp. 1943-1947
    • Leyssen, P.1    Balzarini, J.2    De Clercq, E.3    Neyts, J.4
  • 25
    • 0035811016 scopus 로고    scopus 로고
    • RNA virus error catastrophe: Direct molecular test by using ribavirin
    • Crotty S, Cameron CE, Andino R. 2001. RNA virus error catastrophe: direct molecular test by using ribavirin. Proc Natl Acad Sci USA 98:6895-6900. http://dx.doi.org/10.1073/pnas.111085598.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6895-6900
    • Crotty, S.1    Cameron, C.E.2    Andino, R.3
  • 26
    • 78751545582 scopus 로고    scopus 로고
    • Ribavirin potentiates interferon action by augmenting interferon-stimulated gene induction in hepatitis C virus cell culture models
    • Thomas E, Feld JJ, Li Q, Hu Z, Fried MW, Liang TJ. 2011. Ribavirin potentiates interferon action by augmenting interferon-stimulated gene induction in hepatitis C virus cell culture models. Hepatology 53:32-41. http://dx.doi.org/10.1002/hep.23985.
    • (2011) Hepatology , vol.53 , pp. 32-41
    • Thomas, E.1    Feld, J.J.2    Li, Q.3    Hu, Z.4    Fried, M.W.5    Liang, T.J.6
  • 29
    • 0034650342 scopus 로고    scopus 로고
    • Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents
    • Liu S, Neidhardt EA, Grossman TH, Ocain T, Clardy J. 2000. Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents. Structure 8:25-33. http://dx.doi.org/10.1016/S0969-2126 (00)00077-0.
    • (2000) Structure , vol.8 , pp. 25-33
    • Liu, S.1    Neidhardt, E.A.2    Grossman, T.H.3    Ocain, T.4    Clardy, J.5
  • 30
    • 0032958286 scopus 로고    scopus 로고
    • Inhibitors of dihydroorotate dehydrogenase
    • Batt DG. 1999. Inhibitors of dihydroorotate dehydrogenase. Expert Opin Ther Pat 9:41-54. http://dx.doi.org/10.1517/13543776.9.1.41.
    • (1999) Expert Opin Ther Pat , vol.9 , pp. 41-54
    • Batt, D.G.1
  • 31
    • 35349023246 scopus 로고    scopus 로고
    • Construction and characterization of a stable subgenomic dengue virus type 2 replicon system for antiviral compound and siRNA testing
    • Ng CY, Gu F, Phong WY, Chen Y-L, Lim SP, Davidson A, Vasudevan SG. 2007. Construction and characterization of a stable subgenomic dengue virus type 2 replicon system for antiviral compound and siRNA testing. Antiviral Res 76:222-231. http://dx.doi.org/10.1016/j.antiviral.2007.06.007.
    • (2007) Antiviral Res , vol.76 , pp. 222-231
    • Ng, C.Y.1    Gu, F.2    Phong, W.Y.3    Chen, Y.-L.4    Lim, S.P.5    Davidson, A.6    Vasudevan, S.G.7
  • 33
    • 33748794547 scopus 로고    scopus 로고
    • Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
    • Chou T-C. 2006. Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol Rev 58:621-681. http://dx.doi.org/10.1124/pr.58.3.10.
    • (2006) Pharmacol Rev , vol.58 , pp. 621-681
    • Chou, T.-C.1
  • 34
    • 15944377364 scopus 로고    scopus 로고
    • Assessing in vitro combinations of antifungal drugs against yeasts and filamentous fungi: Comparison of different drug interaction models
    • Meletiadis J, Verweij PE, TeDorsthorst DT, Meis JF, Mouton JW. 2005. Assessing in vitro combinations of antifungal drugs against yeasts and filamentous fungi: comparison of different drug interaction models. Med Mycol 43:133-152. http://dx.doi.org/10.1080/13693780410001731547.
    • (2005) Med Mycol , vol.43 , pp. 133-152
    • Meletiadis, J.1    Verweij, P.E.2    Tedorsthorst, D.T.3    Meis, J.F.4    Mouton, J.W.5
  • 35
    • 84873326152 scopus 로고    scopus 로고
    • Understanding synergy
    • Geary N. 2013. Understanding synergy. Am J Physiol Endocrinol Metab 304:E237-E253. http://dx.doi.org/10.1152/ajpendo.00308.2012.
    • (2013) Am J Physiol Endocrinol Metab , vol.304 , pp. E237-E253
    • Geary, N.1
  • 37
    • 84903774295 scopus 로고    scopus 로고
    • Investigational nucleoside and nucleotide polymerase inhibitors and their use in treating hepatitis C virus
    • Gentile I, Coppola N, Buonomo AR, Zappulo E, Borgia G. 2014. Investigational nucleoside and nucleotide polymerase inhibitors and their use in treating hepatitis C virus. Expert Opin Investig Drugs 23:1211-1223. http://dx.doi.org/10.1517/13543784.2014.921680.
    • (2014) Expert Opin Investig Drugs , vol.23 , pp. 1211-1223
    • Gentile, I.1    Coppola, N.2    Buonomo, A.R.3    Zappulo, E.4    Borgia, G.5
  • 39
    • 0034110319 scopus 로고    scopus 로고
    • Potentiation of the anti-HIV activity of zalcitabine and lamivudine by a CTP synthase inhibitor, 3-deazauridine
    • Gao WY, Johns DG, Mitsuya H. 2000. Potentiation of the anti-HIV activity of zalcitabine and lamivudine by a CTP synthase inhibitor, 3-deazauridine. Nucleosides Nucleotides Nucleic Acids 19:371-377. http://dx.doi.org/10.1080/15257770008033015.
    • (2000) Nucleosides Nucleotides Nucleic Acids , vol.19 , pp. 371-377
    • Gao, W.Y.1    Johns, D.G.2    Mitsuya, H.3
  • 40
    • 33645396484 scopus 로고    scopus 로고
    • Functional classification of drugs by properties of their pairwise interactions
    • Yeh P, Tschumi AI, Kishony R. 2006. Functional classification of drugs by properties of their pairwise interactions. Nat Genet 38:489-494. http://dx.doi.org/10.1038/ng1755.
    • (2006) Nat Genet , vol.38 , pp. 489-494
    • Yeh, P.1    Tschumi, A.I.2    Kishony, R.3
  • 42
    • 84860536610 scopus 로고    scopus 로고
    • Susceptibility and response of human blood monocyte subsets to primary dengue virus infection
    • Wong KL, Chen W, Balakrishnan T, Toh YX, Fink K, Wong S-C. 2012. Susceptibility and response of human blood monocyte subsets to primary dengue virus infection. PLoS One 7:e36435. http://dx.doi.org/10.1371/journal.pone.0036435.
    • (2012) PLoS One , vol.7 , pp. e36435
    • Wong, K.L.1    Chen, W.2    Balakrishnan, T.3    Toh, Y.X.4    Fink, K.5    Wong, S.-C.6
  • 44
    • 33747620519 scopus 로고    scopus 로고
    • Systems biology and combination therapy in the quest for clinical efficacy
    • Fitzgerald JB, Schoeberl B, Nielsen UB, Sorger PK. 2006. Systems biology and combination therapy in the quest for clinical efficacy. Nat Chem Biol 2:458-466. http://dx.doi.org/10.1038/nchembio817.
    • (2006) Nat Chem Biol , vol.2 , pp. 458-466
    • Fitzgerald, J.B.1    Schoeberl, B.2    Nielsen, U.B.3    Sorger, P.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.