Structural biology of dengue virus enzymes: Towards rational design of therapeutics

Antiviral Research

Volumn 96, Issue 2, 2012, Pages 115-126

  Noble, Christian G ^a   Shi, Pei Yong ^a  

^a NOVARTIS INSTITUTE FOR TROPICAL DISEASES   (Singapore)

Author keywords

Crystal structure; Dengue virus; Enzyme; Flavivirus; Structure based design

Indexed keywords

AURINTRICARBOXYLIC ACID; HINOKIFLAVONE; METHYLTRANSFERASE; NONSTRUCTURAL PROTEIN 1; NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4; NONSTRUCTURAL PROTEIN 4A; PROTEINASE; RNA POLYMERASE; SINEFUNGIN; VIRUS ENZYME; VIRUS RNA;

ANTIVIRAL ACTIVITY; BINDING AFFINITY; CRYSTAL STRUCTURE; DENGUE; DENGUE VIRUS; DRUG DESIGN; ENZYME BINDING; ENZYME STRUCTURE; HUMAN; NONHUMAN; PRIORITY JOURNAL; REVIEW; RNA STRUCTURE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANTIVIRAL AGENTS; CRYSTALLOGRAPHY, X-RAY; DENGUE VIRUS; DRUG DESIGN; HUMANS; METHYLTRANSFERASES; MODELS, MOLECULAR; PEPTIDE HYDROLASES; PROTEIN CONFORMATION; RNA REPLICASE; VIRAL PROTEINS;

DENGUE VIRUS; FLAVIVIRUS;

EID: 84867236960     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2012.09.007     Document Type: Review

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