-
1
-
-
0032748385
-
Antitumor activity of thalidomide in refractory multiple myeloma
-
Singhal S, Mehta J, Desikan R, et al. Antitumor activity of thalidomide in refractory multiple myeloma. N Engl J Med. 1999;341(21): 1565-1571.
-
(1999)
N Engl J Med
, vol.341
, Issue.21
, pp. 1565-1571
-
-
Singhal, S.1
Mehta, J.2
Desikan, R.3
-
2
-
-
36349010285
-
Multiple Myeloma (009) Study Investigators. Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America
-
Weber DM, Chen C, Niesvizky R, et al; Multiple Myeloma (009) Study Investigators. Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America. N Engl J Med. 2007; 357(21):2133-2142.
-
(2007)
N Engl J Med
, vol.357
, Issue.21
, pp. 2133-2142
-
-
Weber, D.M.1
Chen, C.2
Niesvizky, R.3
-
3
-
-
70450230539
-
Long-term follow-up on overall survival from the MM-009 and MM-010 phase III trials of lenalidomide plus dexamethasone in patients with relapsed or refractory multiple myeloma
-
Dimopoulos MA, Chen C, Spencer A, et al. Long-term follow-up on overall survival from the MM-009 and MM-010 phase III trials of lenalidomide plus dexamethasone in patients with relapsed or refractory multiple myeloma. Leukemia. 2009;23(11):2147-2152.
-
(2009)
Leukemia
, vol.23
, Issue.11
, pp. 2147-2152
-
-
Dimopoulos, M.A.1
Chen, C.2
Spencer, A.3
-
4
-
-
34548539381
-
Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: Combination therapy improves time to progression
-
Orlowski RZ, Nagler A, Sonneveld P, et al. Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: combination therapy improves time to progression. J Clin Oncol. 2007;25(25): 3892-3901.
-
(2007)
J Clin Oncol
, vol.25
, Issue.25
, pp. 3892-3901
-
-
Orlowski, R.Z.1
Nagler, A.2
Sonneveld, P.3
-
6
-
-
75149186681
-
Lenalidomide, bortezomib, and dexamethasone in relapsed/refractory multiple myeloma (MM): Encouraging outcomes and tolerability in a phase II study
-
Anderson KC, Jagannath S, Jakubowiak A, et al. Lenalidomide, bortezomib, and dexamethasone in relapsed/refractory multiple myeloma (MM): encouraging outcomes and tolerability in a phase II study. J Clin Oncol. 2009;2009(15S):8536.
-
(2009)
J Clin Oncol
, vol.2009
, Issue.15 S
, pp. 8536
-
-
Anderson, K.C.1
Jagannath, S.2
Jakubowiak, A.3
-
7
-
-
84873337611
-
Lenalidomide (Revlimid), bortezomib (Velcade) and dexamethasone for heavily pretreated relapsed or refractory multiple myeloma
-
Jimenez-Zepeda VH, Reece DE, Trudel S, Chen C, Tiedemann R, Kukreti V. Lenalidomide (Revlimid), bortezomib (Velcade) and dexamethasone for heavily pretreated relapsed or refractory multiple myeloma. Leuk Lymphoma. 2013;54(3):555-560.
-
(2013)
Leuk Lymphoma
, vol.54
, Issue.3
, pp. 555-560
-
-
Jimenez-Zepeda, V.H.1
Reece, D.E.2
Trudel, S.3
Chen, C.4
Tiedemann, R.5
Kukreti, V.6
-
8
-
-
84860898706
-
Cyclophosphamide-bortezomibdexamethasone (CyBorD) produces rapid and complete hematologic response in patients with AL amyloidosis
-
Mikhael JR, Schuster SR, Jimenez-Zepeda VH, et al. Cyclophosphamide-bortezomibdexamethasone (CyBorD) produces rapid and complete hematologic response in patients with AL amyloidosis. Blood. 2012;119(19):4391-4394.
-
(2012)
Blood
, vol.119
, Issue.19
, pp. 4391-4394
-
-
Mikhael, J.R.1
Schuster, S.R.2
Jimenez-Zepeda, V.H.3
-
9
-
-
67650882695
-
Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: High response rates in a phase II clinical trial
-
Reeder CB, Reece DE, Kukreti V, et al. Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: high response rates in a phase II clinical trial. Leukemia. 2009;23(7):1337-1341.
-
(2009)
Leukemia
, vol.23
, Issue.7
, pp. 1337-1341
-
-
Reeder, C.B.1
Reece, D.E.2
Kukreti, V.3
-
10
-
-
77951453409
-
Once- versus twice-weekly bortezomib induction therapy with CyBorD in newly diagnosed multiple myeloma
-
Reeder CB, Reece DE, Kukreti V, et al. Once- versus twice-weekly bortezomib induction therapy with CyBorD in newly diagnosed multiple myeloma. Blood. 2010;115(16):3416-3417.
-
(2010)
Blood
, vol.115
, Issue.16
, pp. 3416-3417
-
-
Reeder, C.B.1
Reece, D.E.2
Kukreti, V.3
-
11
-
-
84938970441
-
Phase III trial of bortezomib, cyclophosphamide and dexamethasone (VCD) versus bortezomib, doxorubicin and dexamethasone (PAd) in newly diagnosed myeloma
-
Mai EK, Bertsch U, Dürig J, et al. Phase III trial of bortezomib, cyclophosphamide and dexamethasone (VCD) versus bortezomib, doxorubicin and dexamethasone (PAd) in newly diagnosed myeloma. Leukemia. 2015;29(8): 1721-1729.
-
(2015)
Leukemia
, vol.29
, Issue.8
, pp. 1721-1729
-
-
Mai, E.K.1
Bertsch, U.2
Dürig, J.3
-
12
-
-
73349115580
-
Multicenter, phase I, dose-escalation trial of lenalidomide plus bortezomib for relapsed and relapsed/refractory multiple myeloma
-
Richardson PG, Weller E, Jagannath S, et al. Multicenter, phase I, dose-escalation trial of lenalidomide plus bortezomib for relapsed and relapsed/refractory multiple myeloma. J Clin Oncol. 2009;27(34):5713-5719.
-
(2009)
J Clin Oncol
, vol.27
, Issue.34
, pp. 5713-5719
-
-
Richardson, P.G.1
Weller, E.2
Jagannath, S.3
-
13
-
-
77954618168
-
Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma
-
Richardson PG, Weller E, Lonial S, et al. Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma. Blood. 2010;116(5): 679-686.
-
(2010)
Blood
, vol.116
, Issue.5
, pp. 679-686
-
-
Richardson, P.G.1
Weller, E.2
Lonial, S.3
-
14
-
-
84893289821
-
A phase 2 trial of lenalidomide, bortezomib, and dexamethasone in patients with relapsed and relapsed/refractory myeloma
-
Richardson PG, Xie W, Jagannath S, et al. A phase 2 trial of lenalidomide, bortezomib, and dexamethasone in patients with relapsed and relapsed/refractory myeloma. Blood. 2014; 123(10):1461-1469.
-
(2014)
Blood
, vol.123
, Issue.10
, pp. 1461-1469
-
-
Richardson, P.G.1
Xie, W.2
Jagannath, S.3
-
15
-
-
84920599743
-
Carfilzomib lenalidomide and dexamethasone for relapsed multiple myeloma
-
Stewart AK, Rajkumar SV, Dimopoulos MA, et al; ASPIRE Investigators. Carfilzomib, lenalidomide, and dexamethasone for relapsed multiple myeloma. N Engl J Med. 2015;372(2):142-152.
-
(2015)
N Engl J Med
, vol.372
, Issue.2
, pp. 142-152
-
-
ASPIRE Investigators1
Stewart, A.K.2
Rajkumar, S.V.3
Dimopoulos, M.A.4
-
16
-
-
84883472160
-
U. S. Food and Drug Administration approval: Carfilzomib for the treatment of multiple myeloma
-
Herndon TM, Deisseroth A, Kaminskas E, et al. U. S. Food and Drug Administration approval: carfilzomib for the treatment of multiple myeloma. Clin Cancer Res. 2013;19(17):4559-4563.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.17
, pp. 4559-4563
-
-
Herndon, T.M.1
Deisseroth, A.2
Kaminskas, E.3
-
17
-
-
84867295563
-
A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma
-
Siegel DS, Martin T, Wang M, et al. A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma. Blood. 2012;120(14):2817-2825.
-
(2012)
Blood
, vol.120
, Issue.14
, pp. 2817-2825
-
-
Siegel, D.S.1
Martin, T.2
Wang, M.3
-
18
-
-
84862507585
-
An open-label, single-arm, phase 2 (PX-171-004) study of singleagent carfilzomib in bortezomib-naive patients with relapsed and/or refractory multiple myeloma
-
Vij R, Wang M, Kaufman JL, et al. An open-label, single-arm, phase 2 (PX-171-004) study of singleagent carfilzomib in bortezomib-naive patients with relapsed and/or refractory multiple myeloma. Blood. 2012;119(24):5661-5670.
-
(2012)
Blood
, vol.119
, Issue.24
, pp. 5661-5670
-
-
Vij, R.1
Wang, M.2
Kaufman, J.L.3
-
19
-
-
84865552564
-
An openlabel, single-arm, phase 2 study of single-agent carfilzomib in patients with relapsed and/or refractory multiple myeloma who have been previously treated with bortezomib
-
Vij R, Siegel DS, Jagannath S, et al. An openlabel, single-arm, phase 2 study of single-agent carfilzomib in patients with relapsed and/or refractory multiple myeloma who have been previously treated with bortezomib. Br J Haematol. 2012;158(6):739-748.
-
(2012)
Br J Haematol
, vol.158
, Issue.6
, pp. 739-748
-
-
Vij, R.1
Siegel, D.S.2
Jagannath, S.3
-
20
-
-
4344693453
-
Phase i study of an immunomodulatory thalidomide analog, CC-4047, in relapsed or refractory multiple myeloma
-
Schey SA, Fields P, Bartlett JB, et al. Phase I study of an immunomodulatory thalidomide analog, CC-4047, in relapsed or refractory multiple myeloma. J Clin Oncol. 2004;22(16): 3269-3276.
-
(2004)
J Clin Oncol
, vol.22
, Issue.16
, pp. 3269-3276
-
-
Schey, S.A.1
Fields, P.2
Bartlett, J.B.3
-
21
-
-
84892576029
-
Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells
-
Krönke J, Udeshi ND, Narla A, et al. Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells. Science. 2014; 343(6168):301-305.
-
(2014)
Science
, vol.343
, Issue.6168
, pp. 301-305
-
-
Krönke, J.1
Udeshi, N.D.2
Narla, A.3
-
22
-
-
84892593087
-
The myeloma drug lenalidomide promotes the cereblondependent destruction of Ikaros proteins
-
Lu G, Middleton RE, Sun H, et al. The myeloma drug lenalidomide promotes the cereblondependent destruction of Ikaros proteins. Science. 2014;343(6168):305-309.
-
(2014)
Science
, vol.343
, Issue.6168
, pp. 305-309
-
-
Lu, G.1
Middleton, R.E.2
Sun, H.3
-
23
-
-
84988241358
-
International uniform response criteria for multiple myeloma
-
Durie BG, Harousseau JL, Miguel JS, et al; International Myeloma Working Group. International uniform response criteria for multiple myeloma. Leukemia. 2006;20(9):1467-1473.
-
(2006)
Leukemia
, vol.20
, Issue.9
, pp. 1467-1473
-
-
Durie, B.G.1
Harousseau, J.L.2
Miguel, J.S.3
-
24
-
-
18244428600
-
Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant
-
Bladé J, Samson D, Reece D, et al. Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant. Br J Haematol. 1998;102(5): 1115-1123.
-
(1998)
Br J Haematol
, vol.102
, Issue.5
, pp. 1115-1123
-
-
Bladé, J.1
Samson, D.2
Reece, D.3
-
25
-
-
84877089105
-
Phase Ib dose-escalation study (PX-171-006) of carfilzomib, lenalidomide, and low-dose dexamethasone in relapsed or progressive multiple myeloma
-
Niesvizky R, Martin TG III, Bensinger WI, et al. Phase Ib dose-escalation study (PX-171-006) of carfilzomib, lenalidomide, and low-dose dexamethasone in relapsed or progressive multiple myeloma. Clin Cancer Res. 2013;19(8): 2248-2256.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.8
, pp. 2248-2256
-
-
Niesvizky, R.1
Martin, T.G.2
Bensinger, W.I.3
-
26
-
-
84906043062
-
A phase I/II trial of cyclophosphamide, carfilzomib, thalidomide and dexamethasone (CYCLONE) in patients with newly diagnosed multiple myeloma: Final results of MTD expansion cohort [abstract]
-
Mikhael JR, Reeder CB, Libby EN, et al. A phase I/II trial of cyclophosphamide, carfilzomib, thalidomide and dexamethasone (CYCLONE) in patients with newly diagnosed multiple myeloma: final results of MTD expansion cohort [abstract]. Blood. 2013;122(21):3179.
-
(2013)
Blood
, vol.122
, Issue.21
, pp. 3179
-
-
Mikhael, J.R.1
Reeder, C.B.2
Libby, E.N.3
-
27
-
-
84905721292
-
Dose escalation phase 2 trial of carfilzomib combined with thalidomide and low-dose dexamethasone in newly diagnosed transplant eligible patients with multiple myeloma. A trial of the European Myeloma Network [abstract]
-
Sonneveld P, Asselberg-Hacker E, Zweegman S, et al. Dose escalation phase 2 trial of carfilzomib combined with thalidomide and low-dose dexamethasone in newly diagnosed, transplant eligible patients with multiple myeloma. A trial of the European Myeloma Network [abstract]. Blood. 2013;122(21):688.
-
(2013)
Blood
, vol.122
, Issue.21
, pp. 688
-
-
Sonneveld, P.1
Asselberg-Hacker, E.2
Zweegman, S.3
-
28
-
-
84906053160
-
A phase II study with carfilzomib, cyclophosphamide and dexamethasone (CCd) for newly diagnosed multiple myeloma [abstract]
-
Bringhen S, Cerrato C, Petrucci MT, et al. A phase II study with carfilzomib, cyclophosphamide and dexamethasone (CCd) for newly diagnosed multiple myeloma [abstract]. Blood. 2013;122(21): 685.
-
(2013)
Blood
, vol.122
, Issue.21
, pp. 685
-
-
Bringhen, S.1
Cerrato, C.2
Petrucci, M.T.3
-
29
-
-
84948972919
-
Phase 1/1b study of the efficacy and safety of the combination of panobinostat 1 carfilzomib in patients with relapsed and/or refractory multiple myeloma [abstract]
-
Abstract 4081
-
Shah JJ, Thomas SK, Weber DM, et al. Phase 1/1b study of the efficacy and safety of the combination of panobinostat 1 carfilzomib in patients with relapsed and/or refractory multiple myeloma [abstract]. Blood. 2012;120(21). Abstract 4081.
-
(2012)
Blood
, vol.120
, Issue.21
-
-
Shah, J.J.1
Thomas, S.K.2
Weber, D.M.3
-
30
-
-
84948956404
-
Phase I/II study of panobinostat and carfilzomib in patients (pts) with relapsed or refractory multiple myeloma (MM), interim phase i safety analysis [abstract]
-
Abstract 4048
-
Berdeja JG, Hart L, Lamar R, Murphy P, Morgan S, Flinn IW. Phase I/II study of panobinostat and carfilzomib in patients (pts) with relapsed or refractory multiple myeloma (MM), interim phase I safety analysis [abstract]. Blood. 2012;120(21). Abstract 4048.
-
(2012)
Blood
, vol.120
, Issue.21
-
-
Berdeja, J.G.1
Hart, L.2
Lamar, R.3
Murphy, P.4
Morgan, S.5
Flinn, I.W.6
-
31
-
-
84856719479
-
Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib: A multicenter international myeloma working group study [published correction appears in Leukemia. 2012; 26(5): 1153]
-
Kumar SK, Lee JH, Lahuerta JJ, et al; International Myeloma Working Group. Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib: a multicenter international myeloma working group study [published correction appears in Leukemia. 2012;26(5):1153]. Leukemia. 2012;26(1):149-157.
-
(2012)
Leukemia
, vol.26
, Issue.1
, pp. 149-157
-
-
Kumar, S.K.1
Lee, J.H.2
Lahuerta, J.J.3
-
32
-
-
78149468560
-
Pomalidomide (CC4047) plus low dose dexamethasone (Pom/dex) is active and well tolerated in lenalidomide refractory multiple myeloma (MM)
-
Lacy MQ, Hayman SR, Gertz MA, et al. Pomalidomide (CC4047) plus low dose dexamethasone (Pom/dex) is active and well tolerated in lenalidomide refractory multiple myeloma (MM). Leukemia. 2010;24(11): 1934-1939.
-
(2010)
Leukemia
, vol.24
, Issue.11
, pp. 1934-1939
-
-
Lacy, M.Q.1
Hayman, S.R.2
Gertz, M.A.3
-
33
-
-
80052937408
-
Pomalidomide plus low-dose dexamethasone in myeloma refractory to both bortezomib and lenalidomide: Comparison of 2 dosing strategies in dual-refractory disease
-
Lacy MQ, Allred JB, Gertz MA, et al. Pomalidomide plus low-dose dexamethasone in myeloma refractory to both bortezomib and lenalidomide: comparison of 2 dosing strategies in dual-refractory disease. Blood. 2011;118(11): 2970-2975.
-
(2011)
Blood
, vol.118
, Issue.11
, pp. 2970-2975
-
-
Lacy, M.Q.1
Allred, J.B.2
Gertz, M.A.3
-
34
-
-
84884702483
-
Pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone alone for patients with relapsed and refractory multiple myeloma (MM-003): A randomised, open-label, phase 3 trial
-
San Miguel J, Weisel K, Moreau P, et al. Pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone alone for patients with relapsed and refractory multiple myeloma (MM-003): a randomised, open-label, phase 3 trial. Lancet Oncol. 2013;14(11): 1055-1066.
-
(2013)
Lancet Oncol
, vol.14
, Issue.11
, pp. 1055-1066
-
-
San Miguel, J.1
Weisel, K.2
Moreau, P.3
-
35
-
-
84897668614
-
Pomalidomide plus low-dose dexamethasone in relapsed or refractory multiple myeloma (RRMM) with deletion (del)17p and/or translocation t(4;14) [abstract]
-
Leleu X, Karlin L, Macro M, et al. Pomalidomide plus low-dose dexamethasone in relapsed or refractory multiple myeloma (RRMM) with deletion (del)17p and/or translocation t(4;14) [abstract]. Blood. 2013;122(21):689.
-
(2013)
Blood
, vol.122
, Issue.21
, pp. 689
-
-
Leleu, X.1
Karlin, L.2
Macro, M.3
|