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Volumn 123, Issue 10, 2014, Pages 1461-1469

A phase 2 trial of lenalidomide, bortezomib, and dexamethasone in patients with relapsed and relapsed/refractory myeloma

(26)  Richardson, Paul G a   Xie, Wanling a   Jagannath, Sundar b   Jakubowiak, Andrzej c   Lonial, Sagar d   Raje, Noopur S e   Alsina, Melissa f   Ghobrial, Irene M a   Schlossman, Robert L a   Munshi, Nikhil C a   Mazumder, Amitabha g   Vesole, David H h   Kaufman, Jonathan L d   Colson, Kathleen a   McKenney, Mary a   Lunde, Laura E a   Feather, John a   Maglio, Michelle E a   Warren, Diane a   Francis, Dixil d   more..


Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; DEXAMETHASONE; LENALIDOMIDE;

EID: 84893289821     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-07-517276     Document Type: Article
Times cited : (172)

References (50)
  • 1
    • 59449106820 scopus 로고    scopus 로고
    • Expected long-term survival of patients diagnosed with multiple myeloma in 2006-2010
    • Brenner H, Gondos A, Pulte D. Expected long-term survival of patients diagnosed with multiple myeloma in 2006-2010. Haematologica. 2009;94(2):270-275.
    • (2009) Haematologica , vol.94 , Issue.2 , pp. 270-275
    • Brenner, H.1    Gondos, A.2    Pulte, D.3
  • 2
    • 41949130070 scopus 로고    scopus 로고
    • Improved survival in multiple myeloma and the impact of novel therapies
    • Kumar SK, Rajkumar SV, Dispenzieri A, et al. Improved survival in multiple myeloma and the impact of novel therapies. Blood. 2008;111(5):2516- 2520.
    • (2008) Blood , vol.111 , Issue.5 , pp. 2516-2520
    • Kumar, S.K.1    Rajkumar, S.V.2    Dispenzieri, A.3
  • 8
    • 0035300479 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
    • Hideshima T, Richardson P, Chauhan D, et al. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res. 2001;61(7):3071-3076. (Pubitemid 32691956)
    • (2001) Cancer Research , vol.61 , Issue.7 , pp. 3071-3076
    • Hideshima, T.1    Richardson, P.2    Chauhan, D.3    Palombella, V.J.4    Elliott, P.J.5    Adams, J.6    Anderson, K.C.7
  • 9
    • 82155178738 scopus 로고    scopus 로고
    • Bortezomib plus dexamethasone versus reduced-dose bortezomib, thalidomide plus dexamethasone as induction treatment before autologous stem cell transplantation in newly diagnosed multiple myeloma
    • questions 5982
    • Moreau P, Avet-Loiseau H, Facon T, et al. Bortezomib plus dexamethasone versus reduced-dose bortezomib, thalidomide plus dexamethasone as induction treatment before autologous stem cell transplantation in newly diagnosed multiple myeloma. Blood. 2011;118(22):5752-5758, questions 5982.
    • (2011) Blood , vol.118 , Issue.22 , pp. 5752-5758
    • Moreau, P.1    Avet-Loiseau, H.2    Facon, T.3
  • 10
    • 78049488759 scopus 로고    scopus 로고
    • Bortezomib plus dexamethasone is superior to vincristine plus doxorubicin plus dexamethasone as induction treatment prior to autologous stemcell transplantation in newly diagnosed multiple myeloma: Results of the IFM 2005-01 phase III trial
    • Harousseau JL, Attal M, Avet-Loiseau H, et al. Bortezomib plus dexamethasone is superior to vincristine plus doxorubicin plus dexamethasone as induction treatment prior to autologous stemcell transplantation in newly diagnosed multiple myeloma: results of the IFM 2005-01 phase III trial. J Clin Oncol. 2010;28(30):4621-4629.
    • (2010) J Clin Oncol , vol.28 , Issue.30 , pp. 4621-4629
    • Harousseau, J.L.1    Attal, M.2    Avet-Loiseau, H.3
  • 11
    • 79960666079 scopus 로고    scopus 로고
    • Lenalidomide, bortezomib, pegylated liposomal doxorubicin, and dexamethasone in newly diagnosed multiple myeloma: A phase 1/2 Multiple Myeloma Research Consortium trial
    • Jakubowiak AJ, Griffith KA, Reece DE, et al. Lenalidomide, bortezomib, pegylated liposomal doxorubicin, and dexamethasone in newly diagnosed multiple myeloma: a phase 1/2 Multiple Myeloma Research Consortium trial. Blood. 2011;118(3):535-543.
    • (2011) Blood , vol.118 , Issue.3 , pp. 535-543
    • Jakubowiak, A.J.1    Griffith, K.A.2    Reece, D.E.3
  • 12
    • 73249146496 scopus 로고    scopus 로고
    • Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: An open-label randomised controlled trial
    • Eastern Cooperative Oncology Group
    • Rajkumar SV, Jacobus S, Callander NS, et al Eastern Cooperative Oncology Group. Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial. Lancet Oncol. 2010;11(1):29-37.
    • (2010) Lancet Oncol , vol.11 , Issue.1 , pp. 29-37
    • Rajkumar, S.V.1    Jacobus, S.2    Callander, N.S.3
  • 13
    • 77954618168 scopus 로고    scopus 로고
    • Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma
    • Richardson PG, Weller E, Lonial S, et al. Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma. Blood. 2010;116(5):679-686.
    • (2010) Blood , vol.116 , Issue.5 , pp. 679-686
    • Richardson, P.G.1    Weller, E.2    Lonial, S.3
  • 14
    • 78649686431 scopus 로고    scopus 로고
    • Lenalidomide and high-dose dexamethasone compared with dexamethasone as initial therapy for multiple myeloma: A randomized Southwest Oncology Group trial (S0232)
    • Zonder JA, Crowley J, Hussein MA, et al. Lenalidomide and high-dose dexamethasone compared with dexamethasone as initial therapy for multiple myeloma: a randomized Southwest Oncology Group trial (S0232). Blood. 2010;116(26):5838-5841.
    • (2010) Blood , vol.116 , Issue.26 , pp. 5838-5841
    • Zonder, J.A.1    Crowley, J.2    Hussein, M.A.3
  • 15
    • 78650303860 scopus 로고    scopus 로고
    • Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: A randomised phase 3 study
    • GIMEMA Italian Myeloma Network
    • Cavo M, Tacchetti P, Patriarca F, et al GIMEMA Italian Myeloma Network. Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised phase 3 study. Lancet. 2010;376(9758):2075-2085.
    • (2010) Lancet , vol.376 , Issue.9758 , pp. 2075-2085
    • Cavo, M.1    Tacchetti, P.2    Patriarca, F.3
  • 16
    • 84864055971 scopus 로고    scopus 로고
    • Superiority of the triple combination of bortezomib-thalidomide- dexamethasone over the dual combination of thalidomide-dexamethasone in patients with multiple myeloma progressing or relapsing after autologous transplantation: The MMVAR/IFM 2005-04 Randomized Phase III Trial from the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation
    • Garderet L, Iacobelli S, Moreau P, et al. Superiority of the triple combination of bortezomib-thalidomide-dexamethasone over the dual combination of thalidomide-dexamethasone in patients with multiple myeloma progressing or relapsing after autologous transplantation: the MMVAR/IFM 2005-04 Randomized Phase III Trial from the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation. J Clin Oncol. 2012;30(20):2475-2482.
    • (2012) J Clin Oncol , vol.30 , Issue.20 , pp. 2475-2482
    • Garderet, L.1    Iacobelli, S.2    Moreau, P.3
  • 17
    • 84865444078 scopus 로고    scopus 로고
    • Superiority of bortezomib, thalidomide, and dexamethasone (VTD) as induction pretransplantation therapy in multiple myeloma: A randomized phase 3 PETHEMA/GEM study
    • Programa para el Estudio y la Terapéutica de las Hemopatías Malignas/Grupo Español de Mieloma (PETHEMA/GEM) group
    • Rosiñol L, Oriol A, Teruel AI, et al; Programa para el Estudio y la Terapéutica de las Hemopatías Malignas/Grupo Español de Mieloma (PETHEMA/GEM) group. Superiority of bortezomib, thalidomide, and dexamethasone (VTD) as induction pretransplantation therapy in multiple myeloma: a randomized phase 3 PETHEMA/GEM study. Blood. 2012;120(8):1589-1596.
    • (2012) Blood , vol.120 , Issue.8 , pp. 1589-1596
    • Rosiñol, L.1    Oriol, A.2    Teruel, A.I.3
  • 18
    • 84867337239 scopus 로고    scopus 로고
    • (Bortezomib plus lenalidomide/thalidomide)- vs. (bortezomib or lenalidomide/thalidomide)-containing regimens as induction therapy in newly diagnosed multiple myeloma: A meta-analysis of randomized controlled trials
    • Wang A, Duan Q, Liu X, et al. (Bortezomib plus lenalidomide/thalidomide)- vs. (bortezomib or lenalidomide/thalidomide)-containing regimens as induction therapy in newly diagnosed multiple myeloma: a meta-analysis of randomized controlled trials. Ann Hematol. 2012;91(11):1779-1784.
    • (2012) Ann Hematol , vol.91 , Issue.11 , pp. 1779-1784
    • Wang, A.1    Duan, Q.2    Liu, X.3
  • 19
    • 73349115580 scopus 로고    scopus 로고
    • Multicenter, phase I, dose-escalation trial of lenalidomide plus bortezomib for relapsed and relapsed/refractory multiple myeloma
    • Richardson PG, Weller E, Jagannath S, et al. Multicenter, phase I, dose-escalation trial of lenalidomide plus bortezomib for relapsed and relapsed/refractory multiple myeloma. J Clin Oncol. 2009;27(34):5713-5719.
    • (2009) J Clin Oncol , vol.27 , Issue.34 , pp. 5713-5719
    • Richardson, P.G.1    Weller, E.2    Jagannath, S.3
  • 20
    • 18244428600 scopus 로고    scopus 로고
    • Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation
    • DOI 10.1046/j.1365-2141.1998.00930.x
    • Bladé J, Samson D, Reece D, et al Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant. Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Br J Haematol. 1998;102(5):1115-1123. (Pubitemid 28435189)
    • (1998) British Journal of Haematology , vol.102 , Issue.5 , pp. 1115-1123
    • Blade, J.1    Samson, D.2    Reece, D.3    Apperley, J.4    Bjorkstrand, B.5    Gahrton, G.6    Gertz, M.7    Giralt, S.8    Jagannath, S.9    Vesole, D.10
  • 21
    • 84873990173 scopus 로고    scopus 로고
    • A prospective, international phase 2 study of bortezomib retreatment in patients with relapsed multiple myeloma
    • Petrucci MT, Giraldo P, Corradini P, et al. A prospective, international phase 2 study of bortezomib retreatment in patients with relapsed multiple myeloma. Br J Haematol. 2013;160(5):649-659.
    • (2013) Br J Haematol , vol.160 , Issue.5 , pp. 649-659
    • Petrucci, M.T.1    Giraldo, P.2    Corradini, P.3
  • 22
    • 79952105543 scopus 로고    scopus 로고
    • Bortezomib retreatment in relapsed multiple myeloma - Results from a retrospective multicentre survey in Germany and Switzerland
    • Hrusovsky I, Emmerich B, von Rohr A, et al. Bortezomib retreatment in relapsed multiple myeloma - results from a retrospective multicentre survey in Germany and Switzerland. Oncology. 2010;79(3-4):247-254.
    • (2010) Oncology , vol.79 , Issue.3-4 , pp. 247-254
    • Hrusovsky, I.1    Emmerich, B.2    Von Rohr, A.3
  • 23
    • 70349515834 scopus 로고    scopus 로고
    • Retreatment with bortezomib alone or in combination for patients with multiple myeloma following an initial response to bortezomib
    • Sood R, Carloss H, Kerr R, et al. Retreatment with bortezomib alone or in combination for patients with multiple myeloma following an initial response to bortezomib. Am J Hematol. 2009;84(10):657-660.
    • (2009) Am J Hematol , vol.84 , Issue.10 , pp. 657-660
    • Sood, R.1    Carloss, H.2    Kerr, R.3
  • 24
    • 58149235237 scopus 로고    scopus 로고
    • Utility of bortezomib retreatment in relapsed or refractory multiple myeloma patients: A multicenter case series
    • Wolf J, Richardson PG, Schuster M, LeBlanc A, Walters IB, Battleman DS. Utility of bortezomib retreatment in relapsed or refractory multiple myeloma patients: a multicenter case series. Clin Adv Hematol Oncol. 2008;6(10):755-760.
    • (2008) Clin Adv Hematol Oncol , vol.6 , Issue.10 , pp. 755-760
    • Wolf, J.1    Richardson, P.G.2    Schuster, M.3    LeBlanc, A.4    Walters, I.B.5    Battleman, D.S.6
  • 28
    • 84877089105 scopus 로고    scopus 로고
    • Phase Ib dose-escalation study (PX-171-006) of carfilzomib, lenalidomide, and low-dose dexamethasone in relapsed or progressive multiple myeloma
    • Niesvizky R, Martin TG III, Bensinger WI, et al. Phase Ib dose-escalation study (PX-171-006) of carfilzomib, lenalidomide, and low-dose dexamethasone in relapsed or progressive multiple myeloma. Clin Cancer Res. 2013;19(8):2248-2256.
    • (2013) Clin Cancer Res , vol.19 , Issue.8 , pp. 2248-2256
    • Niesvizky, R.1    Martin III, T.G.2    Bensinger, W.I.3
  • 29
    • 84887609779 scopus 로고    scopus 로고
    • Phase 2 dose-expansion study (PX-171-006) of carfilzomib, lenalidomide, and low-dose dexamethasone in relapsed or progressive multiple myeloma
    • Wang M, Martin T, Bensinger W, et al. Phase 2 dose-expansion study (PX-171-006) of carfilzomib, lenalidomide, and low-dose dexamethasone in relapsed or progressive multiple myeloma. Blood. 2013;122(18):3122-3128.
    • (2013) Blood , vol.122 , Issue.18 , pp. 3122-3128
    • Wang, M.1    Martin, T.2    Bensinger, W.3
  • 30
    • 84868096248 scopus 로고    scopus 로고
    • Updated survival analysis of a randomized phase III study of subcutaneous versus intravenous bortezomib in patients with relapsed multiple myeloma
    • Arnulf B, Pylypenko H, Grosicki S, et al. Updated survival analysis of a randomized phase III study of subcutaneous versus intravenous bortezomib in patients with relapsed multiple myeloma. Haematologica. 2012;97(12):1925-1928.
    • (2012) Haematologica , vol.97 , Issue.12 , pp. 1925-1928
    • Arnulf, B.1    Pylypenko, H.2    Grosicki, S.3
  • 31
    • 79955461011 scopus 로고    scopus 로고
    • Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: A randomised, phase 3, non-inferiority study
    • Moreau P, Pylypenko H, Grosicki S, et al. Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomised, phase 3, non-inferiority study. Lancet Oncol. 2011;12(5):431-440.
    • (2011) Lancet Oncol , vol.12 , Issue.5 , pp. 431-440
    • Moreau, P.1    Pylypenko, H.2    Grosicki, S.3
  • 32
    • 70450230539 scopus 로고    scopus 로고
    • Long-term follow-up on overall survival from the MM-009 and MM-010 phase III trials of lenalidomide plus dexamethasone in patients with relapsed or refractory multiple myeloma
    • Dimopoulos MA, Chen C, Spencer A, et al. Long-term follow-up on overall survival from the MM-009 and MM-010 phase III trials of lenalidomide plus dexamethasone in patients with relapsed or refractory multiple myeloma. Leukemia. 2009;23(11):2147-2152.
    • (2009) Leukemia , vol.23 , Issue.11 , pp. 2147-2152
    • Dimopoulos, M.A.1    Chen, C.2    Spencer, A.3
  • 33
    • 84881016175 scopus 로고    scopus 로고
    • Phase II study of bortezomib-dexamethasone alone or with added cyclophosphamide or lenalidomide for sub-optimal response as secondline treatment for patients with multiple myeloma
    • Dimopoulos MA, Beksac M, Benboubker L, et al. Phase II study of bortezomib-dexamethasone alone or with added cyclophosphamide or lenalidomide for sub-optimal response as secondline treatment for patients with multiple myeloma. Haematologica. 2013;98(8):1264-1272.
    • (2013) Haematologica , vol.98 , Issue.8 , pp. 1264-1272
    • Dimopoulos, M.A.1    Beksac, M.2    Benboubker, L.3
  • 34
    • 84856719479 scopus 로고    scopus 로고
    • Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib: A multicenter international myeloma working group study
    • International Myeloma Working Group published correction appears in Leukemia. 2012;26(5):1153
    • Kumar SK, Lee JH, Lahuerta JJ, et al International Myeloma Working Group. Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib: a multicenter international myeloma working group study [published correction appears in Leukemia. 2012;26(5):1153]. Leukemia. 2012;26(1):149-157.
    • (2012) Leukemia , vol.26 , Issue.1 , pp. 149-157
    • Kumar, S.K.1    Lee, J.H.2    Lahuerta, J.J.3
  • 35
    • 84873337611 scopus 로고    scopus 로고
    • Lenalidomide (Revlimid), bortezomib (Velcade) and dexamethasone for heavily pretreated relapsed or refractory multiple myeloma
    • Jimenez-Zepeda VH, Reece DE, Trudel S, Chen C, Tiedemann R, Kukreti V. Lenalidomide (Revlimid), bortezomib (Velcade) and dexamethasone for heavily pretreated relapsed or refractory multiple myeloma. Leuk Lymphoma. 2013;54(3):555-560.
    • (2013) Leuk Lymphoma , vol.54 , Issue.3 , pp. 555-560
    • Jimenez-Zepeda, V.H.1    Reece, D.E.2    Trudel, S.3    Chen, C.4    Tiedemann, R.5    Kukreti, V.6
  • 36
    • 77952170192 scopus 로고    scopus 로고
    • Rapid control of previously untreated multiple myeloma with bortezomib-lenalidomide dexamethasone (BLD)
    • Wang M, Delasalle K, Giralt S, Alexanian R. Rapid control of previously untreated multiple myeloma with bortezomib-lenalidomide dexamethasone (BLD). Hematology. 2010; 15(2):70-73.
    • (2010) Hematology , vol.15 , Issue.2 , pp. 70-73
    • Wang, M.1    Delasalle, K.2    Giralt, S.3    Alexanian, R.4
  • 38
    • 84859632261 scopus 로고    scopus 로고
    • Management of treatment-emergent peripheral neuropathy in multiple myeloma
    • Richardson PG, Delforge M, Beksac M, et al. Management of treatment-emergent peripheral neuropathy in multiple myeloma. Leukemia. 2012;26(4):595-608.
    • (2012) Leukemia , vol.26 , Issue.4 , pp. 595-608
    • Richardson, P.G.1    Delforge, M.2    Beksac, M.3
  • 39
    • 84881004497 scopus 로고    scopus 로고
    • Bortezomib (Btz)-induced peripheral neuropathy (BiPN) in previously untreated MM: Impact of dexamethasone (Dex) schedule
    • abstract P-416
    • Kumar S, Laubach JP, Sonneveld P, et al. Bortezomib (Btz)-induced peripheral neuropathy (BiPN) in previously untreated MM: impact of dexamethasone (Dex) schedule [abstract P-416]. Clin Lymphoma Myeloma Leuk. 2013; 13(Suppl 1):S235.
    • (2013) Clin Lymphoma Myeloma Leuk , vol.13 , Issue.SUPPL. 1
    • Kumar, S.1    Laubach, J.P.2    Sonneveld, P.3
  • 40
    • 78049528177 scopus 로고    scopus 로고
    • Treatment-related peripheral neuropathy in multiple myeloma: The challenge continues
    • Delforge M, Bladé J, Dimopoulos MA, et al. Treatment-related peripheral neuropathy in multiple myeloma: the challenge continues. Lancet Oncol. 2010;11(11):1086-1095.
    • (2010) Lancet Oncol , vol.11 , Issue.11 , pp. 1086-1095
    • Delforge, M.1    Bladé, J.2    Dimopoulos, M.A.3
  • 41
    • 80052789122 scopus 로고    scopus 로고
    • Low venous thromboembolic risk with bortezomib in multiple myeloma and potential protective effect with thalidomide/lenalidomide-based therapy: Review of data from phase 3 trials and studies of novel combination regimens
    • Zangari M, Fink L, Zhan F, Tricot G. Low venous thromboembolic risk with bortezomib in multiple myeloma and potential protective effect with thalidomide/lenalidomide-based therapy: review of data from phase 3 trials and studies of novel combination regimens. Clin Lymphoma Myeloma Leuk. 2011;11(2):228-236.
    • (2011) Clin Lymphoma Myeloma Leuk , vol.11 , Issue.2 , pp. 228-236
    • Zangari, M.1    Fink, L.2    Zhan, F.3    Tricot, G.4
  • 42
    • 54849413402 scopus 로고    scopus 로고
    • Updated survival analyses after prolonged follow-up of the phase 2, multicenter CREST study of bortezomib in relapsed or refractory multiple myeloma
    • Jagannath S, Barlogie B, Berenson JR, et al. Updated survival analyses after prolonged follow-up of the phase 2, multicenter CREST study of bortezomib in relapsed or refractory multiple myeloma. Br J Haematol. 2008;143(4):537-540.
    • (2008) Br J Haematol , vol.143 , Issue.4 , pp. 537-540
    • Jagannath, S.1    Barlogie, B.2    Berenson, J.R.3
  • 43
    • 44249092118 scopus 로고    scopus 로고
    • The addition of liposomal doxorubicin to bortezomib, thalidomide and dexamethasone significantly improves clinical outcome of advanced multiple myeloma
    • DOI 10.1111/j.1365-2141.2008.07147.x
    • Ciolli S, Leoni F, Casini C, Breschi C, Santini V, Bosi A. The addition of liposomal doxorubicin to bortezomib, thalidomide and dexamethasone significantly improves clinical outcome of advanced multiple myeloma. Br J Haematol. 2008;141(6):814-819. (Pubitemid 351724874)
    • (2008) British Journal of Haematology , vol.141 , Issue.6 , pp. 814-819
    • Ciolli, S.1    Leoni, F.2    Casini, C.3    Breschi, C.4    Santini, V.5    Bosi, A.6
  • 44
    • 84355161833 scopus 로고    scopus 로고
    • Thalidomide, dexamethasone, Doxil and Velcade (ThaDD-V) followed by consolidation/maintenance therapy in patients with relapsedrefractory multiple myeloma
    • Offidani M, Corvatta L, Polloni C, et al. Thalidomide, dexamethasone, Doxil and Velcade (ThaDD-V) followed by consolidation/maintenance therapy in patients with relapsedrefractory multiple myeloma. Ann Hematol. 2011;90(12):1449-1456.
    • (2011) Ann Hematol , vol.90 , Issue.12 , pp. 1449-1456
    • Offidani, M.1    Corvatta, L.2    Polloni, C.3
  • 45
    • 84872460585 scopus 로고    scopus 로고
    • Randomized phase II study of bortezomib, thalidomide, and dexamethasone with or without cyclophosphamide as induction therapy in previously untreated multiple myeloma
    • Ludwig H, Viterbo L, Greil R, et al. Randomized phase II study of bortezomib, thalidomide, and dexamethasone with or without cyclophosphamide as induction therapy in previously untreated multiple myeloma. J Clin Oncol. 2013;31(2):247-255.
    • (2013) J Clin Oncol , vol.31 , Issue.2 , pp. 247-255
    • Ludwig, H.1    Viterbo, L.2    Greil, R.3
  • 46
    • 84860907057 scopus 로고    scopus 로고
    • Randomized, multicenter, phase 2 study (EVOLUTION) of combinations of bortezomib, dexamethasone, cyclophosphamide, and lenalidomide in previously untreated multiple myeloma
    • Kumar S, Flinn I, Richardson PG, et al. Randomized, multicenter, phase 2 study (EVOLUTION) of combinations of bortezomib, dexamethasone, cyclophosphamide, and lenalidomide in previously untreated multiple myeloma. Blood. 2012;119(19):4375-4382.
    • (2012) Blood , vol.119 , Issue.19 , pp. 4375-4382
    • Kumar, S.1    Flinn, I.2    Richardson, P.G.3
  • 47
    • 57849161431 scopus 로고    scopus 로고
    • The combination of bortezomib, melphalan, dexamethasone and intermittent thalidomide is an effective regimen for relapsed/refractory myeloma and is associated with improvement of abnormal bone metabolism and angiogenesis
    • Terpos E, Kastritis E, Roussou M, et al. The combination of bortezomib, melphalan, dexamethasone and intermittent thalidomide is an effective regimen for relapsed/refractory myeloma and is associated with improvement of abnormal bone metabolism and angiogenesis. Leukemia. 2008;22(12):2247-2256.
    • (2008) Leukemia , vol.22 , Issue.12 , pp. 2247-2256
    • Terpos, E.1    Kastritis, E.2    Roussou, M.3
  • 48
    • 84863775772 scopus 로고    scopus 로고
    • A phase 2 study of pegylated liposomal doxorubicin, bortezomib, dexamethasone and lenalidomide for patients with relapsed/refractory multiple myeloma
    • Berenson JR, Yellin O, Kazamel T, et al. A phase 2 study of pegylated liposomal doxorubicin, bortezomib, dexamethasone and lenalidomide for patients with relapsed/refractory multiple myeloma. Leukemia. 2012;26(7):1675-1680.
    • (2012) Leukemia , vol.26 , Issue.7 , pp. 1675-1680
    • Berenson, J.R.1    Yellin, O.2    Kazamel, T.3
  • 49
    • 84865333050 scopus 로고    scopus 로고
    • A phase 1/2 study of carfilzomib in combination with lenalidomide and low-dose dexamethasone as a frontline treatment for multiple myeloma
    • Jakubowiak AJ, Dytfeld D, Griffith KA, et al. A phase 1/2 study of carfilzomib in combination with lenalidomide and low-dose dexamethasone as a frontline treatment for multiple myeloma. Blood. 2012;120(9):1801-1809.
    • (2012) Blood , vol.120 , Issue.9 , pp. 1801-1809
    • Jakubowiak, A.J.1    Dytfeld, D.2    Griffith, K.A.3
  • 50
    • 84879562212 scopus 로고    scopus 로고
    • A phase 1/2 study of weekly MLN9708, an investigational oral proteasome inhibitor, in combination with lenalidomide and dexamethasone in patients with previously untreated multiple myeloma (MM)
    • abstract Abstract 332
    • Kumar SK, Berdeja JD, Niesvizky R, et al. A phase 1/2 study of weekly MLN9708, an investigational oral proteasome inhibitor, in combination with lenalidomide and dexamethasone in patients with previously untreated multiple myeloma (MM) [abstract]. Blood. 2012;120(21) Abstract 332.
    • (2012) Blood , vol.120 , Issue.21
    • Kumar, S.K.1    Berdeja, J.D.2    Niesvizky, R.3


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