ESI-LC-MS Method for Haptoglobin Fucosylation Analysis in Hepatocellular Carcinoma and Liver Cirrhosis

Journal of Proteome Research

Volumn 14, Issue 12, 2015, Pages 5388-5395

  Zhang, Yiwei ^a,b   Zhu, Jianhui ^a   Yin, Haidi ^a   Marrero, Jorge ^c   Zhang, Xin Xiang ^b   Lubman, David M ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b PEKING UNIVERSITY   (China)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

cirrhosis; electrospray ionization; fucosylation; hepatocellular cancer; Liquid chromatography mass spectrometry; Meladrazine

Indexed keywords

GLYCAN; HAPTOGLOBIN; FUCOSE; HP PROTEIN, HUMAN; POLYSACCHARIDE; TUMOR MARKER;

ARTICLE; CLINICAL ARTICLE; ELECTROSPRAY; FUCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYDROPHILIC INTERACTION CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MASS SPECTROMETRY; PRIORITY JOURNAL; SERUM; BLOOD; CHEMICAL STRUCTURE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; GLYCOSYLATION; LIMIT OF DETECTION; LIVER TUMOR; PROCEDURES; REPRODUCIBILITY; STATISTICS AND NUMERICAL DATA;

BIOMARKERS, TUMOR; CARCINOMA, HEPATOCELLULAR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FUCOSE; GLYCOSYLATION; HAPTOGLOBINS; HUMANS; LIMIT OF DETECTION; LIVER CIRRHOSIS; LIVER NEOPLASMS; MOLECULAR STRUCTURE; POLYSACCHARIDES; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84949009930     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/acs.jproteome.5b00792     Document Type: Article

References (18)

1. Tan, Z. J.; Yin, H. D.; Nie, S.; Lin, Z. X.; Zhu, J. H.; Ruffin, M. T.; Anderson, M. A.; Simeone, D. M.; Lubman, D. M. Large-Scale Identification of Core-Fucosylated Glycopeptide Sites in Pancreatic Cancer Serum Using Mass Spectrometry J. Proteome Res. 2015, 14, 1968-1978 10.1021/acs.jproteome.5b00068
2. Wu, J.; Xie, X. L.; Liu, Y. S.; He, J. T.; Benitez, R.; Buckanovich, R. J.; Lubman, D. M. Identification and Confirmation of Differentially Expressed Fucosylated Glycoproteins in the Serum of Ovarian Cancer Patients Using a Lectin Array and LC-MS/MS J. Proteome Res. 2012, 11, 4541-4552 10.1021/pr300330z
3. Li, Q. K.; Gabrielson, E.; Zhang, H. Application of glycoproteomics for the discovery of biomarkers in lung cancer Proteomics: Clin. Appl. 2012, 6, 244-256 10.1002/prca.201100042
4. Marrero, J. A.; Feng, Z. D.; Wang, Y. H.; Nguyen, M. H.; Befeler, A. S.; Roberts, L. R.; Reddy, K. R.; Harnois, D.; Llovet, J. M.; Normolle, D.; Dalhgren, J.; Chia, D.; Lok, A. S.; Wagner, P. D.; Srivastava, S.; Schwartz, M. alpha-Fetoprotein, Des-gamma Carboxyprothrombin, and Lectin-Bound alpha-Fetoprotein in Early Hepatocellular Carcinoma Gastroenterology 2009, 137, 110-118 10.1053/j.gastro.2009.04.005
5. Lee, H. J.; Cha, H. J.; Lim, J. S.; Lee, S. H.; Song, S. Y.; Kim, H.; Hancock, W. S.; Yoo, J. S.; Paik, Y. K. Abundance-Ratio-Based Semiquantitative Analysis of Site-Specific N-Linked Glycopeptides Present in the Plasma of Hepatocellular Carcinoma Patients J. Proteome Res. 2014, 13 (5) 2328-2338 10.1021/pr4011519
6. Fanayan, S.; Hincapie, M.; Hancock, W. S. Using lectins to harvest the plasma/serum glycoproteome Electrophoresis 2012, 33, 1746-1754 10.1002/elps.201100567
7. Sato, Y.; Nakata, K.; Kato, Y.; Shima, M.; Ishii, N.; Koji, T.; Taketa, K.; Endo, Y.; Nagataki, S. Early Recognition of Hepatocellular-Carcinoma Based on Altered Profiles of Alpha-Fetoprotein N. Engl. J. Med. 1993, 328, 1802-1806 10.1056/NEJM199306243282502
8. Nakagawa, T.; Miyoshi, E.; Yakushijin, T.; Hiramatsu, N.; Igura, T.; Hayashi, N.; Taniguchi, N.; Kondo, A. Glycomic analysis of alpha-fetoprotein L3 in hepatoma cell lines and hepatocellular carcinoma patients J. Proteome Res. 2008, 7, 2222-2233 10.1021/pr700841q
9. Yin, H. D.; Lin, Z. X.; Nie, S.; Wu, J.; Tan, Z. J.; Zhu, J. H.; Dai, J. L.; Feng, Z. D.; Marrero, J.; Lubman, D. M. Mass-Selected Site-Specific Core-Fucosylation of Ceruloplasmin in Alcohol-Related Hepatocellular Carcinoma J. Proteome Res. 2014, 13, 2887-2896 10.1021/pr500043k
10. Zhu, J. H.; Lin, Z. X.; Wu, J.; Yin, H. D.; Dai, J. L.; Feng, Z. D.; Marrero, J.; Lubman, D. M. Analysis of Serum Haptoglobin Fucosylation in Hepatocellular Carcinoma and Liver Cirrhosis of Different Etiologies J. Proteome Res. 2014, 13, 2986-2997 10.1021/pr500128t
11. Ciucanu, I.; Kerek, F. A simple and rapid method for the permethylation of carbohydrates Carbohydr. Res. 1984, 131, 209-217 10.1016/0008-6215(84)85242-8
12. Harvey, D. J. Electrospray mass spectrometry and fragmentation of N-linked carbohydrates derivatized at the reducing terminus J. Am. Soc. Mass Spectrom. 2000, 11, 900-915 10.1016/S1044-0305(00)00156-2
13. Tie, C.; Zhang, X. X. A new labelling reagent for glycans analysis by capillary electrophoresis-mass spectrometry Anal. Methods 2012, 4, 357-359 10.1039/c2ay05741g
14. Zhu, J. H.; Wu, J.; Yin, H. D.; Marrero, J.; Lubman, D. M. Mass spectrometric N-glycan analysis of haptoglobin from patient serum samples using a 96-well plate format J. Proteome Res. 2015, 10.1021/acs.jproteome.5b00662
15. Zhao, M.-Z.; Zhang, Y.-W.; Yuan, F.; Deng, Y.; Liu, J.-X.; Zhou, Y.-L.; Zhang, X.-X. Hydrazino-s-triazine based labelling reagents for highly sensitive glycan analysis via liquid chromatography-electrospray mass spectrometry Talanta 2015, 144, 992-997 10.1016/j.talanta.2015.07.045
16. Ceroni, A.; Maass, K.; Geyer, H.; Geyer, R.; Dell, A.; Haslam, S. M. GlycoWorkbench: A Tool for the Computer-Assisted Annotation of Mass Spectra of Glycans J. Proteome Res. 2008, 7, 1650-1659 10.1021/pr7008252
17. McCarthy, C.; Saldova, R.; O'Brien, M. E.; Bergin, D. A.; Carroll, T. P.; Keenan, J.; Meleady, P.; Henry, M.; Clynes, M.; Rudd, P. M.; Reeves, E. P.; McElvaney, N. G. Increased Outer Arm and Core Fucose Residues on the N-Glycans of Mutated Alpha-1 Antitrypsin Protein from Alpha-1 Antitrypsin Deficient Individuals J. Proteome Res. 2014, 13, 596-605 10.1021/pr400752t
18. Lin, Z. X.; Yin, H. D.; Lo, A.; Ruffin, M. T.; Anderson, M. A.; Simeone, D. M.; Lubman, D. M. Label-free relative quantification of alpha-2-macroglobulin site-specific core-fucosylation in pancreatic cancer by LC-MS/MS Electrophoresis 2014, 35, 2108-2115 10.1002/elps.201300376