Electrospray mass spectrometry and fragmentation of N-linked carbohydrates derivatized at the reducing terminus

Journal of the American Society for Mass Spectrometry

Volumn 11, Issue 10, 2000, Pages 900-915

  Harvey, David J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINATION; ESTERS; HYDROGEN; IONS; MASS SPECTROMETRY; SUGARS;

FRAGMENTATION;

CARBOHYDRATES;

2 AMINOACRIDONE; 2 AMINOBENZAMIDE; 2 AMINOPYRIDINE; 3 AMINOQUINOLINE; 4 AMINOBENZOIC ACID; CARBOHYDRATE DERIVATIVE; GLYCOPROTEIN; SUGAR; UNCLASSIFIED DRUG;

MASS SPECTROMETRY;

AMINATION; ARTICLE; CARBOHYDRATE ANALYSIS; CHEMICAL REACTION KINETICS; DERIVATIZATION; ENERGY; FLUORESCENCE; IONIZATION; MASS SPECTROMETRY;

AMINATION; CARBOHYDRATE SEQUENCE; CARBOHYDRATES; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; POLYSACCHARIDES; REDUCING AGENTS; SCHIFF BASES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 0034475474     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1044-0305(00)00156-2     Document Type: Article

References (49)

1. Precolumn derivatization for chromatographic and electrophoretic analysis of carbohydrates
2. Desorption mass spectrometry of oligosaccharides coupled with hydrophobic chromophores
3. Sensitive analysis of oligosaccharides derivatised with 4-aminobenzoic acid 2-(diethylamino)ethyl ester by matrix-assisted laser desorption/ionization mass spectrometry
4. Reexamination of the pyridylamination used for fluorescence labelling of oligosaccharides and its application to glycoproteins
5. Large scale preparation of PA-oligosaccharides from glycoproteins using an improved extraction method
6. Analysis of oligosaccharides by on-line high-performance liquid chromatography and ion-spray mass spectrometry
7. Electrospray ionization mass spectrometry of pyridylaminated oligosaccharide derivatives; sensitivity and in-source fragmentation
8. High-sensitivity detection and postsource decay of 2-aminopyridine-derivatized oligosaccharides with matrix-assisted laser desorption-ionization mass spectrometry
9. Sensitive detection and structural characterization of trimethyl(p-aminophenyl)-ammonium-derivatized oligosaccharides by electrospray ionization-mass spectrometry and tandem mass spectrometry
10. Comparison of the sensitivities of various derivatives of oligosaccharides in LC/MS with fast atom bombardment and electrospray ionization interfaces
11. Nonselective and efficient fluorescent labeling of glycans using 2-aminobenzamide and anthranilic acid
12. High resolution and high sensitivity methods for oligosaccharide mapping and characterization by normal phase high performance liquid chromatography following derivatization with highly fluorescent anthranilic acid
13. Collision-induced fragmentation of 2-aminobenzamide-labelled neutral N-linked glycans
14. A coordinated high-performance liquid chromatographic, capillary electrophoretic, and mass spectrometric approach for the analysis of oligosaccharide mixtures with 2-aminoacridone
15. High-performance liquid chromatographic analysis of complex N-linked glycans derivatized with 2-aminoacridone
16. Direct structural analysis of 2-aminoacridone derivatised oligosaccharides by high-performance liquid chromatography/mass spectrometric detection
17. Positive and negative ion matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of complex glycans released from hen ovalbumin and derivatized with 2-aminoacridone
18. Profiling of 2-aminoacridone derivatised glycans by electrospray ionization mass spectrometry
19. Carbohydrate release from picomole quantities of glycoprotein and characterisation of glycans by high-performance liquid chromatography and mass spectrometry
20. Analysis of oligosaccharides by microbore high-performance liquid chromatography
21. A probe for the versatile analysis and characterization of N-linked oligosaccharides
22. Cationic derivatization of oligosaccharides with Girard's T reagent for improved performance in matrix-assisted laser desorption/ionization and electrospray mass spectrometry
23. Rapid, sensitive structure analysis of oligosaccharides
24. A systematic nomenclature for carbohydrate fragmentations in FAB-MS/MS spectra of glycoconjugates
25. Structural analysis of oligosaccharides by tandem mass spectrometry; Collisional activation of sodium adduct ions
26. Structure analysis of branched oligosaccharides using post-source decay in matrix-assisted laser desorption/ionization mass spectrometry
27. Collision-induced dissociation of alkali m cationized and permethylated oligosaccharides: influence of the collision energy and of the collision gas for the assignment of linkage position
28. High-energy collision-induced fragmentation of complex oligosaccharides ionized by matrix-assisted laser desorption/ionization mass spectrometry
29. Linkage position determination in oligosaccharides; MS/MS study of lithium-cationised carbohydrates
30. Linkage position determination in lithium-catonised disaccharides; tandem mass spectrometry and semiempirical calculations
31. Oligosaccharide characterization with high-energy collision-induced dissociation mass spectrometry
32. Carbohydrate molecular weight profiling, sequence, linkage and branching data; ES-MS and CID
33. Use of hydrazine to release in intact and unreduced form both N- and O-linked oligosaccharides from glycoproteins
34. Enzymatic sequence analysis of glycoprotein glycans
35. Quantitative aspects of the matrix-assisted laser desorption mass spectrometry of complex oligosaccharides
36. Structural analysis of oligosaccharides derivatized with 4-aminobenzoic acid 2-(diethylamino)ethyl ester by matrix-assisted laser desorption/ionization mass spectrometry
37. A detailed structural characterization of ribonuclease B oligosaccharides by 1H NMR spectroscopy and mass spectrometry
38. Comparison of fragmentation modes for the structural determination of complex oligosaccharides ionized by matrix-assisted laser desorption/ionization mass spectrometry
39. Post-source decay fragmentation of N-linked carbohydrates from ovalbumin and related glycoproteins
40. Structural study of the carbohydrate moiety of hen ovomucoid; occurrence of a series of pentaantennary complex-type asparagine-linked sugar chains
41. Structural studies of the sugar chains of hen ovomucoid; Evidence that they are formed mainly by the alternate biosynthetic pathway of asparagine-linked sugar chains
42. 1H-NMR characterization of a hen ovalbumin tyrosinamide N-linked oligosaccharide library
43. Coordination of alkali metals to oligosaccharides dictates fragmentation behavior in matrix assisted laser desorption ionization/Fourier transform mass spectrometry
44. N-[2-Diethylamino)ethyl-4-aminobenzamide derivatives for high sensitivity mass spectrometric detection and structure determination of N-linked carbohydrates
45. Fragmentation reactions in the mass spectrometry analysis of neutral oligosaccharides
46. Effect of structure on the signal strength of oligosaccharides in matrix-assisted laser desorption/ionization mass spectrometry on time-of-flight and magnetic sector instruments
47. Stabilisation of sialic acids in N-linked oligosaccharides and gangliosides for analysis by positive ion matrix-assisted laser desorption-ionization mass spectrometry